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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WTATSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCC
TNYQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTF
PNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQ
WLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTE
FLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRR
WHVARKPLDVYKKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLL
RTNTFRPTMPDEVSRPNYPGIMYLQSEFDLGCTCDDKVENKLEELNKRLHTKGSTKERHLLYGRPAVLYRTSYDILYHTD
FESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAF
LVTNMVPMYPAFKRVWAYFQRVLVKKYASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITSCLD
FTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLH
TYESEIGG

The query sequence (length=808) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5s9m:A 809 809 0.9963 0.9951 0.9951 0.0 8c3o:A, 5dlt:A, 9ent:A, 9eu5:A, 5hrt:A, 5ijq:A, 5ijs:A, 5lia:A, 3nkm:A, 3nkp:A, 5s9l:A, 5s9n:A, 6w35:A, 3wav:A, 3wax:A, 2xr9:A, 7z0n:AAA, 7z3k:AAA, 7z3l:AAA
2 3way:A 787 803 0.9505 0.9759 0.9564 0.0 8c3o:B, 8c3p:A, 8c3p:B, 8c4w:A, 8c7r:A, 5dlv:A, 5dlv:B, 5dlw:A, 5inh:A, 5l0b:A, 5l0b:B, 5l0e:A, 5l0e:B, 5l0k:A, 5l0k:B, 6leh:A, 5lqq:A, 5m0d:A, 5m0e:A, 5m0m:A, 5m0s:A, 7mfh:A, 5mhp:A, 3nkn:A, 3nko:A, 3nkq:A, 3nkr:A, 5ohi:A, 5olb:A, 7p0k:AAA, 7p4j:A, 7p4o:A, 3waw:A, 6y5m:A, 4zg7:A
3 2xrg:A 758 797 0.9369 0.9987 0.9498 0.0
4 4zg9:B 764 802 0.8936 0.9450 0.9002 0.0 5kxa:A, 5m7m:A, 4zg6:A, 4zg6:B, 4zg9:A, 4zga:A
5 6c01:A 819 822 0.4629 0.4567 0.4550 0.0 6c01:B, 6c02:A, 6c02:B
6 5gz4:A 804 817 0.4839 0.4863 0.4786 0.0 7cba:A, 7cba:B, 5gz5:A
7 6wev:AbA 817 824 0.4703 0.4651 0.4612 0.0 8ghr:A, 8ghr:B, 6wet:AaA, 6wet:BaB, 6weu:AbA, 6weu:BbB, 6wev:BbB, 6wew:AbA, 6wew:BaB, 6wfj:AcA, 6wfj:BcB
8 6g4g:D 781 822 0.4579 0.4738 0.4501 0.0 6g4g:A
9 4b56:A 816 821 0.4480 0.4436 0.4409 0.0 6aek:A, 6ael:A, 4b56:B
10 6g4g:B 759 822 0.4480 0.4769 0.4404 0.0
11 6g4g:C 742 815 0.4455 0.4852 0.4417 0.0
12 6f2t:B 722 735 0.4220 0.4723 0.4639 0.0 6f2t:A, 6f2v:A, 6f2v:B, 6f2y:A, 6f2y:B, 6f30:A, 6f30:B, 6f33:A, 6f33:B
13 4gtw:A 706 731 0.3948 0.4518 0.4364 0.0 4gtw:B, 4gtx:A, 4gtx:B, 4gty:A, 4gty:B, 4gtz:A, 4gtz:B, 6xkd:B
14 6xkd:A 679 728 0.3899 0.4639 0.4327 0.0
15 4lqy:A 379 396 0.1671 0.3562 0.3409 3.75e-56 4lr2:A
16 5vem:A 383 387 0.1498 0.3159 0.3127 6.83e-55 5vem:B, 5vem:C
17 5ven:A 382 386 0.1473 0.3115 0.3083 8.22e-55 5ven:B, 5veo:A
18 5tcd:A 388 402 0.1597 0.3325 0.3209 7.36e-51 5udy:A
19 7mw8:C 385 387 0.1399 0.2935 0.2920 1.13e-49 2gsn:A, 2gsn:B, 2gso:A, 2gso:B, 2gsu:A, 2gsu:B, 7mw8:A, 7mw8:D, 7mw8:B, 7mw8:E, 7mw8:F, 7n1s:A, 7n1s:B, 2rh6:A, 2rh6:B
20 5egh:B 393 402 0.1374 0.2824 0.2761 1.81e-47 5ege:A, 5ege:B, 5ege:C, 5ege:D, 5egh:A
21 3szy:A 413 247 0.0767 0.1501 0.2510 2.53e-06 3szz:A, 3t00:A, 3t01:A, 3t02:A
22 1ei6:A 404 238 0.0656 0.1312 0.2227 0.010 1ei6:B, 1ei6:C, 1ei6:D
23 1n2l:A 483 69 0.0297 0.0497 0.3478 0.032 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
24 6s21:A 486 40 0.0210 0.0350 0.4250 0.059 6s21:B, 6s21:C
25 6hhm:A 459 30 0.0161 0.0283 0.4333 0.42
26 7shg:A 591 190 0.0594 0.0812 0.2526 0.82 7shg:B
27 5tj3:A 520 135 0.0433 0.0673 0.2593 1.4 5too:A
28 8ooc:J 448 51 0.0223 0.0402 0.3529 3.0 6fhs:J, 8oof:J, 8oor:J, 8oot:J
29 8eg3:A 554 65 0.0260 0.0379 0.3231 3.0 1p49:A
30 7oz9:BBB 483 47 0.0161 0.0269 0.2766 3.0 7oz9:AAA
31 6b11:A 385 90 0.0334 0.0701 0.3000 3.2 6b11:B
32 5nd5:A 669 65 0.0272 0.0329 0.3385 4.3 5nd5:B
33 4fdi:A 494 61 0.0186 0.0304 0.2459 4.4 4fdi:B, 4fdj:A, 4fdj:B
34 8di0:B 426 30 0.0136 0.0258 0.3667 4.7
35 1y1p:A 342 64 0.0248 0.0585 0.3125 5.3 1y1p:B
36 6vrc:A 1007 74 0.0260 0.0209 0.2838 6.8
37 6vrb:A 1031 74 0.0260 0.0204 0.2838 7.0
38 5fql:A 507 81 0.0285 0.0454 0.2840 8.0 6ioz:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218