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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WSYSQTLSANIQVNALQRYQEMIGGGCSGAFGWACQQFPTGLTPENQEEVTKILFDENIGGLSIVRNDIGSSPGSTILPT
CPATPAGPFNYQWDGSDSCQFNLTKTALKYNPELYVYANAWSAPGCMKTVGTENDGGQICGVRGTNCTYDWRQAYADYLV
QYVKFYQAEGIDISLLGAWNEPDFNPVTYESMESDGFQAKDFLEILYPTVKKAFPNLDVSCCDATGARQERNILYEVQQA
GGEHFFDVATWHNYQSSPERPFNVVGKPNIMTEWADGSGPWNTTWDVSGQLAEGLQWALYMHNAFTNSDTSGYNHWWCAG
GGADNVLISITGNSYEVSSRLWAFASYFRFARPGSVRIGATSSVENVYVSAYENKNGTVSIPVINAAHFPYEVTIDLQGL
KARKRVSTFLTDNSHNVTLMDQSELHGSVLKATVPPRAVQVFWLE

The query sequence (length=445) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8idp:A 446 446 1.0000 0.9978 0.9978 0.0 8idp:C, 8idp:B, 8idp:D, 8idq:A, 8idq:B, 8idq:C, 8idq:D
2 6krn:A 456 452 0.3910 0.3816 0.3850 8.97e-89
3 8cbc:A 455 456 0.3596 0.3516 0.3509 4.70e-74 8c48:A, 8c48:B, 8cbc:B, 7o0e:A, 7o0e:G, 8p67:A, 8p67:B
4 6m5z:A 433 436 0.3551 0.3649 0.3624 1.62e-72 6m5z:B
5 7n6o:A 433 456 0.2742 0.2818 0.2675 1.50e-27 7n6o:B
6 5ngl:B 454 416 0.2337 0.2291 0.2500 4.44e-18 5ngl:A, 5ngl:C
7 2y24:A 383 354 0.2000 0.2324 0.2514 2.11e-13
8 4uqa:A 391 336 0.1843 0.2097 0.2440 1.53e-11 5a6l:A, 5a6m:A, 4ckq:A, 4uqc:A
9 4qaw:A 537 335 0.1820 0.1508 0.2418 2.09e-11 4qaw:B, 4qaw:C, 4qaw:D, 4qaw:E, 4qaw:F, 4qaw:G, 4qaw:H, 4qb1:A, 4qb2:A, 4qb6:A
10 3kl0:A 397 349 0.1933 0.2166 0.2464 1.89e-09 3kl3:A, 3kl3:B, 3kl5:A, 3kl5:B, 3kl5:C
11 2wnw:B 445 80 0.0629 0.0629 0.3500 5.69e-07 2wnw:A
12 9fa6:A 501 437 0.2112 0.1876 0.2151 1.95e-06 8awk:AAA, 8awr:AAA, 8ax3:A, 8ax3:B, 9f9z:A, 9fa3:A, 9fad:A, 9fal:A, 9fay:A, 9faz:A, 9fb2:A, 9fdi:A, 3gxf:B, 3gxf:D, 5lvx:C, 5lvx:B, 5lvx:A, 5lvx:D, 6moz:A, 2nsx:A, 2nsx:B, 2nsx:C, 2nsx:D, 2nt0:A, 2nt0:B, 2nt0:C, 2nt0:D, 7nwv:AAA, 7nwv:BBB, 8p3e:B, 8p41:A, 8p41:B, 6q1n:A, 6q1n:B, 6q1p:A, 6q1p:B, 6q6k:A, 6q6k:B, 6q6l:A, 6q6l:B, 6q6n:A, 6q6n:B, 3rik:B, 3rik:D, 3ril:A, 3ril:B, 3ril:C, 3ril:D, 6t13:B, 6t13:C, 6t13:A, 6t13:D, 6tjq:BBB, 6tn1:AAA, 2v3d:A, 2v3d:B, 2v3e:A, 2v3e:B, 2vt0:A, 2vt0:B, 2wcg:A, 2wcg:B, 2xwd:A, 2xwd:B, 2xwe:A, 2xwe:B, 1y7v:A, 1y7v:B, 6ytp:AAA, 6ytp:BBB, 6ytr:AAA, 6ytr:BBB, 6yut:AAA, 6yut:BBB, 6yv3:AAA, 6yv3:BBB, 6z39:AAA, 6z39:BBB, 6z3i:BBB
13 5nxb:A 644 145 0.0854 0.0590 0.2621 0.027 4ccc:A, 4ccd:A, 4cce:A, 5nxb:B, 4ufh:A, 4ufi:A, 4ufj:A, 4ufk:A, 4ufl:A, 4ufm:A, 6y6s:A, 6y6t:A, 3zr5:A, 3zr6:A
14 5agd:B 344 69 0.0517 0.0669 0.3333 0.40 5agd:A, 4boj:A, 4boj:B, 4boj:C, 4d4b:A, 4d4b:B, 4d4c:A, 4d4c:B, 4d4d:A, 4d4d:B, 5m77:A, 5m77:B, 5n0f:A, 5n0f:B, 7nl5:A, 6zbm:A, 6zbw:A, 6zbw:B, 6zbx:A, 6zbx:B
15 7whg:G 221 54 0.0472 0.0950 0.3889 0.52
16 7u0e:H 224 204 0.1101 0.2188 0.2402 2.0 7u0e:A
17 7o4x:A 103 24 0.0247 0.1068 0.4583 2.9
18 7mi4:A 554 159 0.0944 0.0758 0.2642 3.0 7mi4:B, 7mi4:C, 7mi4:D, 7mi5:A, 7mi5:B, 7mi5:D, 7mi5:C, 7mi9:A, 7mi9:B, 7mi9:C, 7mi9:D, 7mib:A, 7mib:B, 7mib:C, 7mib:D, 7mid:A, 7mid:B
19 7lsu:A 765 81 0.0517 0.0301 0.2840 5.5 7lsa:A, 7lsr:A, 7lst:A
20 5e6f:A 130 23 0.0247 0.0846 0.4783 6.8 5e6f:B
21 5a6q:A 114 50 0.0360 0.1404 0.3200 7.1 5a6q:B, 5a6q:C, 5a6q:D, 5a6x:A, 5a6x:B, 5a6x:C, 5a6x:D, 5a6y:B, 5a6y:C, 5a6y:D, 5a6y:A, 5a6z:A, 5a6z:B, 5a6z:C, 5a6z:D, 5a70:A, 5a70:B, 5a70:C, 5a70:D, 5may:A, 5may:B, 5may:C, 5may:D, 5maz:A, 5maz:B, 5maz:C, 5maz:D, 5mb1:A, 5mb1:B, 5mb1:C, 5mb1:D, 4ut5:A, 4ut5:B, 4ut5:C, 4ut5:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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