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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDN
PTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELG
SSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFD
LMSRRVIAANNRILAERIAKEIQVIP

The query sequence (length=266) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6giu:A 275 266 1.0000 0.9673 1.0000 0.0 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
2 2bji:A 274 266 0.8797 0.8540 0.8797 0.0 2bji:B
3 4as5:A 274 266 0.8609 0.8358 0.8609 6.35e-177 4as5:B, 4as5:C, 4as5:D
4 2czi:A 259 265 0.5188 0.5328 0.5208 2.39e-108 2czh:B
5 6ib8:B 270 257 0.3158 0.3111 0.3268 2.89e-45 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
6 8wdq:A 273 255 0.3083 0.3004 0.3216 3.15e-42 8wdq:B
7 3lv0:A 258 263 0.3421 0.3527 0.3460 1.25e-38 3luz:A, 3lv0:B
8 2p3n:A 256 249 0.2932 0.3047 0.3133 4.97e-36 2p3n:B, 2p3n:C, 2p3n:D
9 3luz:B 234 247 0.3083 0.3504 0.3320 1.52e-34
10 5dw8:A 260 225 0.2594 0.2654 0.3067 5.71e-31 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
11 1dk4:A 252 194 0.2218 0.2341 0.3041 4.54e-20 1dk4:B, 1g0h:A, 1g0h:B, 1g0i:A, 1g0i:B
12 5eyg:B 265 247 0.2293 0.2302 0.2470 5.94e-16 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
13 5eq9:B 260 270 0.2594 0.2654 0.2556 3.86e-15 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
14 5zon:A 256 242 0.2556 0.2656 0.2810 9.49e-15 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
15 6b5z:A 252 200 0.1917 0.2024 0.2550 4.74e-14 6b5z:B, 6b60:A, 6b60:B, 6b61:A, 6b61:B, 6b62:A, 6b62:B, 6b63:A, 6b63:B, 6b64:A, 6b64:B, 6b65:A, 6b65:B, 6b66:A, 6b66:B, 1lbx:A, 1lbx:B, 1lby:A, 1lby:B, 1lbz:A, 1lbz:B
16 4hxv:A 317 304 0.2744 0.2303 0.2401 1.85e-11 4o7i:A
17 4qxd:B 289 256 0.2368 0.2180 0.2461 1.22e-07 4qxd:A
18 8f9y:A 352 212 0.1917 0.1449 0.2406 4.32e-07
19 1k9y:A 354 200 0.1992 0.1497 0.2650 1.75e-06 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
20 2wef:A 303 271 0.2444 0.2145 0.2399 2.93e-06 1jp4:A
21 5djj:A 257 211 0.2030 0.2101 0.2559 2.21e-04 5djg:A, 5djh:A, 5dji:A, 5djk:A
22 3geh:A 442 75 0.0639 0.0385 0.2267 2.1
23 4xf6:A 273 119 0.1278 0.1245 0.2857 3.7 4xf6:B, 4xf7:A, 4xf7:B
24 2ykt:A 225 145 0.1391 0.1644 0.2552 4.5
25 7naf:y 167 37 0.0526 0.0838 0.3784 6.2
26 3rmj:B 308 43 0.0451 0.0390 0.2791 8.8 3rmj:A
27 4dn1:A 389 67 0.0902 0.0617 0.3582 9.4 4dn1:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218