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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMN
ALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSN
PGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFI
VTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADINKWRIKLDDYSTQELGKTIVYL
DGSSQSCRFRECNMGNLICDAMINNNLHVSMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAF
EHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDEL
LRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS

The query sequence (length=514) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7jv8:C 529 523 0.9981 0.9698 0.9809 0.0 7bbj:A, 7bbj:B, 4h1s:A, 4h1s:B, 4h1y:P, 4h2b:A, 4h2f:A, 4h2g:A, 4h2i:A, 6hxw:A, 6hxw:B, 7jv8:A, 7jv8:B, 7jv8:D, 7jv9:A, 7jv9:B, 7p9n:A, 7p9r:A, 7p9t:A, 7pa4:A, 7pb5:A, 7pba:A, 7pbb:A, 7pby:A, 7pcp:A, 7pd9:A, 7qga:A, 7qgl:A, 7qgm:A, 7qgo:A, 6s7f:A, 6s7h:A, 6tve:P, 6tvg:A, 6tvx:A, 6tw0:A, 6twa:A, 6twf:A, 6vc9:A, 6xue:A, 6xue:B, 6xug:A, 6xug:B, 6xuq:A, 6ye1:A, 6ye1:B, 6ye2:A, 6ye2:B, 6z9b:A, 6z9d:A
2 5h7w:B 529 524 0.6926 0.6730 0.6794 0.0 7d0v:A, 7d0v:B, 5h7w:A
3 2z1a:A 507 517 0.3949 0.4004 0.3926 5.48e-106
4 3ztv:A 565 526 0.3054 0.2779 0.2985 2.35e-49 3zu0:A
5 3zu0:B 505 498 0.2879 0.2931 0.2972 5.86e-47
6 3ivd:A 499 508 0.2588 0.2665 0.2618 3.96e-34 3ivd:B, 3ive:A
7 1ho5:A 525 536 0.2665 0.2610 0.2556 1.53e-29 1ho5:B, 1hp1:A, 1hpu:A, 1hpu:B, 1hpu:C, 1hpu:D, 1oi8:A, 1oi8:B, 1ush:A, 2ush:A, 2ush:B, 4wwl:A
8 3gve:A 334 321 0.1809 0.2784 0.2897 2.16e-23 3gve:B
9 4q7f:A 510 467 0.1984 0.2000 0.2184 1.45e-14 3qfk:A
10 5eqv:A 336 292 0.1479 0.2262 0.2603 2.88e-10
11 3jyf:A 336 300 0.1401 0.2143 0.2400 5.12e-10 3jyf:B
12 4uwq:A 548 206 0.1051 0.0985 0.2621 4.99e-09 4uwq:D, 4uwq:G, 4uwq:J, 2wdc:A, 2wdd:A, 2wde:A, 2wdf:A
13 6g90:T 462 81 0.0350 0.0390 0.2222 1.0 7dco:u, 4dgw:A, 5nrl:T, 5zwm:u
14 5cot:A 340 85 0.0525 0.0794 0.3176 1.4 5cou:A, 6vt1:A, 6vt1:B, 6vt1:C, 6vt1:D, 6vt6:A, 6vt8:A, 6vt9:A, 6vtb:A, 6vtd:A, 6vte:A, 6vtf:A, 6vtf:B, 6vtf:C, 6vtf:D
15 6clx:B 342 97 0.0506 0.0760 0.2680 4.9 6clx:A
16 6tj7:A 134 20 0.0214 0.0821 0.5500 5.0
17 8aaf:a 848 45 0.0214 0.0130 0.2444 6.2 8agt:a, 8agu:a, 8agv:a, 8agw:a, 8agx:a, 8agz:a
18 7eap:A 755 67 0.0370 0.0252 0.2836 8.5 5yot:A, 5yot:B, 5yqs:A, 5yqs:B
19 7nhk:H 207 46 0.0292 0.0725 0.3261 9.7 6o8w:D, 6o8x:D, 6o8y:D, 6o8z:D, 6o90:D, 7p7q:H, 7p7r:H, 7p7s:H, 7p7t:H, 7p7u:H, 6w6p:D, 6wu9:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218