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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WDKLLNTKPMKRQVQPNPPTNETRALNLGNTFRSPAFKFLGTLKRSKDPSGLRLGFYGRKADDFMARSIAMQAKASAAGS
GVYTTQCSEGASKGMAENARTASLAKQFRQAQRSAREMSFDYYEGRKYAMKAVGHICNYEEKIFQQYNKTAAAYVMGKQE
TLLSCDRYAQPANKAEEYIQKSVQMQMKKRSIPYGVYTTSCADGTVKGMAENARVAKESANFRARQMSAGAKAAARFNAR
RVANDWHNNGCNYEEKLTSRFPAAASSVRPTTNRY

The query sequence (length=275) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7y4l:MI 275 275 1.0000 1.0000 1.0000 0.0 7ezx:MA, 7ezx:MG, 7ezx:MN, 7ezx:MQ, 6kgx:M1, 6kgx:21, 6kgx:M4, 6kgx:24, 7y4l:ZI, 7y4l:M9, 7y4l:Z9, 7y5e:Z9, 7y5e:M5, 7y5e:Z5, 7y5e:M9, 7y7a:MH, 7y7a:ZH, 7y7a:Ma, 7y7a:Mf, 7y7a:Za, 7y7a:Zf, 7y7a:Mh, 7y7a:Zh
2 7ezx:AB 238 216 0.3527 0.4076 0.4491 1.07e-55 7ezx:wJ, 7ezx:xJ, 7ezx:wL, 7ezx:xL, 7ezx:AM, 6kgx:A8, 6kgx:AA, 6kgx:wE, 6kgx:xE, 6kgx:wG, 6kgx:xG, 7y4l:wF, 7y4l:AH, 7y4l:A4, 7y4l:w8, 7y4l:x8, 7y4l:xF, 7y5e:wF, 7y5e:AJ, 7y5e:wK, 7y5e:AM, 7y5e:xF, 7y5e:xK, 7y7a:A3, 7y7a:w6, 7y7a:x6, 7y7a:AC, 7y7a:wQ, 7y7a:xQ, 7y7a:wT, 7y7a:xT, 7y7a:AV, 7y7a:wb, 7y7a:xb, 7y7a:Ap
3 7ezx:AB 238 99 0.1636 0.1891 0.4545 1.35e-17 7ezx:wJ, 7ezx:xJ, 7ezx:wL, 7ezx:xL, 7ezx:AM, 6kgx:A8, 6kgx:AA, 6kgx:wE, 6kgx:xE, 6kgx:wG, 6kgx:xG, 7y4l:wF, 7y4l:AH, 7y4l:A4, 7y4l:w8, 7y4l:x8, 7y4l:xF, 7y5e:wF, 7y5e:AJ, 7y5e:wK, 7y5e:AM, 7y5e:xF, 7y5e:xK, 7y7a:A3, 7y7a:w6, 7y7a:x6, 7y7a:AC, 7y7a:wQ, 7y7a:xQ, 7y7a:wT, 7y7a:xT, 7y7a:AV, 7y7a:wb, 7y7a:xb, 7y7a:Ap
4 5y6p:lz 251 253 0.3709 0.4064 0.4032 7.45e-54 5y6p:ly, 5y6p:hY, 5y6p:hZ
5 7ezx:A1 257 216 0.3273 0.3502 0.4167 3.20e-50 7ezx:A7, 7ezx:A9, 7ezx:AF, 7ezx:AI, 7ezx:AK, 6kgx:A2, 6kgx:Y3, 6kgx:A6, 6kgx:A7, 6kgx:A9, 6kgx:AB, 6kgx:YD, 6kgx:AF, 6kgx:AI, 6kgx:AJ, 7y4l:AB, 7y4l:AC, 7y4l:AD, 7y4l:AE, 7y4l:AJ, 7y4l:YK, 7y4l:Y1, 7y4l:A2, 7y4l:A5, 7y4l:A6, 7y5e:YA, 7y5e:AD, 7y5e:AE, 7y5e:AG, 7y5e:AH, 7y5e:AO, 7y5e:AQ, 7y5e:A1, 7y5e:A4, 7y5e:Y7, 7y7a:A1, 7y7a:A2, 7y7a:A4, 7y7a:Y5, 7y7a:A8, 7y7a:YD, 7y7a:AF, 7y7a:AI, 7y7a:AK, 7y7a:AM, 7y7a:AP, 7y7a:AR, 7y7a:AS, 7y7a:Ac, 7y7a:Ae, 7y7a:Yg, 7y7a:Yi, 7y7a:Aj, 7y7a:Al, 7y7a:An
6 5y6p:C2 245 246 0.3127 0.3510 0.3496 2.36e-37 5y6p:D2, 5y6p:c3, 5y6p:d3, 5y6p:44, 5y6p:Z5, 5y6p:e8, 5y6p:c8, 5y6p:d8, 5y6p:e9, 5y6p:c9, 5y6p:d9, 5y6p:T8, 5y6p:Y9, 5y6p:aZ, 5y6p:bZ
7 7ezx:BB 250 217 0.3055 0.3360 0.3871 1.21e-36 7ezx:yJ, 7ezx:yL, 7ezx:BM, 6kgx:B8, 6kgx:BA, 6kgx:yE, 6kgx:yG, 7y4l:yF, 7y4l:BH, 7y4l:B4, 7y4l:y8, 7y5e:yF, 7y5e:BJ, 7y5e:yK, 7y5e:BM, 7y7a:B3, 7y7a:y6, 7y7a:BC, 7y7a:yQ, 7y7a:yT, 7y7a:BV, 7y7a:yb, 7y7a:Bp
8 7ezx:BB 250 95 0.1345 0.1480 0.3895 8.36e-12 7ezx:yJ, 7ezx:yL, 7ezx:BM, 6kgx:B8, 6kgx:BA, 6kgx:yE, 6kgx:yG, 7y4l:yF, 7y4l:BH, 7y4l:B4, 7y4l:y8, 7y5e:yF, 7y5e:BJ, 7y5e:yK, 7y5e:BM, 7y7a:B3, 7y7a:y6, 7y7a:BC, 7y7a:yQ, 7y7a:yT, 7y7a:BV, 7y7a:yb, 7y7a:Bp
9 5y6p:A2 277 210 0.2545 0.2527 0.3333 8.36e-31 5y6p:a3, 5y6p:34, 5y6p:Y5, 5y6p:b8, 5y6p:b9, 5y6p:U8, 5y6p:Z9, 5y6p:aY, 5y6p:bY, 5y6p:dw, 5y6p:dx, 5y6p:ey, 5y6p:ez
10 5y6p:A2 277 124 0.1636 0.1625 0.3629 2.48e-13 5y6p:a3, 5y6p:34, 5y6p:Y5, 5y6p:b8, 5y6p:b9, 5y6p:U8, 5y6p:Z9, 5y6p:aY, 5y6p:bY, 5y6p:dw, 5y6p:dx, 5y6p:ey, 5y6p:ez
11 5y6p:eZ 309 219 0.3127 0.2783 0.3927 1.71e-30 5y6p:eY
12 5y6p:gy 260 220 0.2509 0.2654 0.3136 1.37e-25 5y6p:gz
13 9fjl:A 168 164 0.1273 0.2083 0.2134 0.78
14 8ps2:G 2036 32 0.0436 0.0059 0.3750 0.85 3hmj:G, 3hmj:H, 3hmj:I, 8prv:G, 8prw:G, 8prw:J, 8prw:I, 8prw:H, 8prw:K, 8prw:L, 8ps1:G, 8ps9:G, 8psa:G, 8psf:G, 8psg:G, 8psj:G, 8psk:G, 8psl:G, 8psm:G, 8psp:G, 6ql5:I, 6ql5:G, 6ql5:H, 6ql5:L, 6ql5:J, 6ql5:K, 6ql6:G, 6ql6:H, 6ql6:I, 6ql6:J, 6ql6:K, 6ql6:L, 6ql9:G, 6ql9:H, 6ql9:I, 6ql9:J, 6ql9:K, 6ql9:L, 6ta1:G, 6ta1:C, 6ta1:E, 6ta1:L, 6ta1:H, 6ta1:J, 6u5t:G, 6u5u:G, 2uv8:G, 2uv8:H, 2uv8:I, 2vkz:G, 2vkz:H, 2vkz:I
15 8fl2:LK 117 62 0.0691 0.1624 0.3065 1.6 8fkp:LK, 8fkq:LK, 8fkr:LK, 8fks:LK, 8fkt:LK, 8fku:LK, 8fkv:LK, 8fkw:LK, 8fkx:LK, 8fky:LK, 8fkz:LK, 8fl3:LK, 8fl4:LK, 8ink:L, 8ipd:L, 8ipx:L, 8ipy:L, 8ir1:L
16 8ie3:L 131 62 0.0691 0.1450 0.3065 3.0
17 8kgf:A 1261 49 0.0509 0.0111 0.2857 3.9
18 7a01:q2 147 62 0.0691 0.1293 0.3065 4.8 8a3d:U, 5aj0:Aa, 8b5l:a, 8b6c:a, 9bdl:AL28, 9bdn:AL28, 9bdp:AL28, 7bhp:La, 8bhf:N1, 8bpo:Z2, 8btk:Ba, 7cpu:La, 7cpv:La, 4d5y:a, 4d67:a, 6d90:a, 6d9j:a, 9f1b:Ba, 9f1c:Ba, 9f1d:Ba, 7f5s:La, 8fl6:LK, 8fl7:LK, 8fl9:LK, 8fla:LK, 8flb:LK, 8flc:LK, 8fld:LK, 8fle:LK, 8flf:LK, 6frk:a, 6ftg:a, 6fti:a, 6ftj:a, 8g5y:La, 8g5z:La, 8g60:La, 8g61:La, 8g6j:La, 8glp:La, 6gz3:Aa, 6gz4:Aa, 6gz5:Aa, 6hcf:a3, 6hcj:a3, 6hcm:a3, 6hcq:a3, 8idt:L, 8idy:L, 8ifd:2U, 8ife:2U, 8ine:L, 8inf:L, 6ip5:2U, 6ip6:2U, 6ip8:2U, 8ir3:L, 3j7o:a, 3j7p:a, 3j7q:a, 3j7r:a, 3j92:a, 3jag:a, 3jah:a, 3jai:a, 3jaj:a, 3jan:a, 8jdj:f, 8jdk:f, 8jdl:f, 8jdm:f, 8k2c:La, 5lks:La, 6lqm:L, 6lsr:L, 6lss:L, 7ls1:U2, 7ls2:U2, 6lu8:L, 5lzs:a, 5lzt:a, 5lzu:a, 5lzv:a, 5lzw:a, 5lzx:a, 5lzy:a, 5lzz:a, 7mdz:a, 6mtb:a, 6mtc:a, 6mtd:a, 6mte:a, 7nfx:a, 7nwg:a3, 7nwh:a, 7nwi:a, 7o7y:Ba, 7o7z:Ba, 7o80:Ba, 7o81:Ba, 7obr:a, 8ohd:La, 8oj0:La, 8oj5:La, 8oj8:La, 6ole:b, 6olf:b, 6olg:Aa, 6oli:b, 6olz:Aa, 6om0:b, 6om7:b, 7ow7:U, 7oyc:a1, 7oyd:a, 8p2k:Ba, 6p5i:Aa, 6p5j:Aa, 6p5k:Aa, 6p5n:Aa, 8q7z:Ba, 8q87:Ba, 8qfd:a, 7qgg:b, 8qoi:La, 7qvp:La, 7qvp:Ma, 7qwq:a, 7qwr:a, 7qws:a, 6qzp:La, 6r5q:a, 6r6g:a, 6r6p:a, 6r7q:a, 8rjb:a, 8rjc:a, 8rjd:a, 8scb:a, 6sgc:a2, 6swa:Y, 5t2c:U, 6t59:a3, 7tm3:a, 7toq:AL28, 7tor:AL28, 7tut:a, 7ucj:a, 7uck:a, 4ug0:La, 4ujc:Ba, 4ujd:Aa, 4uje:Ca, 4v6x:Ca, 6w6l:b, 6xa1:La, 7xnx:La, 7xny:La, 8xsx:La, 8xsy:La, 8xsz:La, 6y0g:La, 8y0w:La, 8y0x:La, 6y2l:La, 6y57:La, 6y6x:La, 8yoo:La, 8yop:La, 6z6l:La, 6z6m:La, 6z6n:La, 7zjw:Ld, 7zjx:Ld, 6zm7:La, 6zme:La, 6zmi:La, 6zmo:La, 6zvk:q2
19 7tui:B 2033 32 0.0436 0.0059 0.3750 6.7 6u5v:B, 6u5w:B
20 7zzk:B 489 63 0.0582 0.0327 0.2540 7.2 7zzk:A
21 6bum:B 363 60 0.0727 0.0551 0.3333 9.1 6bum:A, 6bum:C, 6bum:D, 6bun:A, 6bun:B, 6bun:C, 6bun:D, 6buo:A, 6buo:D, 6buo:B, 6buo:C, 6bup:A, 6bup:B, 6bup:C, 6bup:D, 6buq:A, 6buq:D, 6buq:B, 6buq:C, 6bur:A, 6bur:B, 6bur:C, 6bur:D, 6cwj:A, 6cwj:B, 6cwj:C, 6cwj:D
22 6vwp:A 435 84 0.0764 0.0483 0.2500 9.1 6vwo:A, 6vwp:B, 6vwp:C, 6vwp:D, 6vwp:E, 6vwp:F, 6vwp:G, 6vwp:H
23 4v58:G 2060 32 0.0400 0.0053 0.3438 9.8 4v58:H, 4v58:I, 4v58:J, 4v58:K, 4v58:L, 4v59:G, 4v59:H, 4v59:I, 4v59:J, 4v59:K, 4v59:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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