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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VYDMPTEIDVRADGALRIITLNRPDSLNSVNDDLHVGLARLWQRLTDDPTARAAVITGAGRAFSAGGDFGYLKELSADAD
LRAKTIRDGREIVLGMARCRIPVVAAVNGPAVGLGCSLVALSDIVYIAENAYLADPHVQVGLVAADGGPLTWPLHISLLL
AKEYALTGTRISAQRAVELGLANHVADDPVAEAIACAKKILELPQQAVESTKRVLNIHLERAVLASLDYALSAESQSFVT
EDFRSIVTKL

The query sequence (length=250) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3rrv:B 254 250 1.0000 0.9843 1.0000 0.0 3rrv:A, 3rrv:C, 3rrv:D, 3rrv:E, 3rrv:F
2 2hw5:C 260 233 0.3040 0.2923 0.3262 5.13e-31
3 1dub:A 260 234 0.2960 0.2846 0.3162 4.98e-29 1dub:B, 1dub:C, 1dub:E, 1dub:F, 1dub:D, 2dub:A, 2dub:B, 2dub:C, 2dub:E, 2dub:F, 2dub:D, 1ey3:A, 1ey3:B, 1ey3:C, 1ey3:D, 1ey3:E, 1ey3:F, 1mj3:A, 1mj3:B, 1mj3:C, 1mj3:E, 1mj3:F
4 5zai:C 259 246 0.3320 0.3205 0.3374 1.81e-26 5zai:A, 5zai:B, 5zai:E
5 3h81:A 256 238 0.3120 0.3047 0.3277 5.65e-26 3h81:C, 3q0g:C, 3q0g:D, 3q0g:F, 3q0j:C, 3q0j:F
6 6slb:AAA 257 207 0.2880 0.2802 0.3478 1.34e-25 6sla:AAA, 6sla:BBB, 6sla:CCC, 6sla:DDD, 6sla:EEE, 6sla:FFF
7 2j5s:A 250 193 0.2160 0.2160 0.2798 8.03e-20 2j5s:B
8 1szo:D 251 231 0.2560 0.2550 0.2771 1.29e-17 1szo:A, 1szo:B, 1szo:C, 1szo:E, 1szo:F, 1szo:G, 1szo:H, 1szo:I, 1szo:J, 1szo:K, 1szo:L
9 5duf:A 245 210 0.2880 0.2939 0.3429 4.14e-17 5dtw:A, 5dtw:D, 5du4:A, 5du6:A, 5du6:B, 5du6:C, 5du8:A, 5du8:B, 5du8:C, 5duc:A, 5duc:B, 5duc:C
10 2a81:A 235 212 0.2560 0.2723 0.3019 6.64e-17
11 3pe8:A 219 197 0.2640 0.3014 0.3350 1.05e-16
12 3t3w:F 248 219 0.2720 0.2742 0.3105 2.01e-16 3t3w:A, 3t3w:B, 3t3w:C, 3t3w:D, 3t3w:E
13 1k39:B 271 213 0.2280 0.2103 0.2676 5.25e-16 1hnu:A, 1k39:A, 1k39:C, 4zdb:A, 4zdb:B, 4zdb:C, 4zdc:A, 4zdc:B, 4zdc:C
14 7bor:A 247 212 0.2560 0.2591 0.3019 1.00e-15 7bor:C
15 5jbx:B 261 217 0.2720 0.2605 0.3134 1.84e-15 5jbx:A
16 3p85:A 224 200 0.2560 0.2857 0.3200 9.74e-15
17 3ome:C 247 215 0.2360 0.2389 0.2744 4.50e-14 3ome:A, 3ome:B, 3ome:D, 3ome:E, 3ome:F
18 3bpt:A 362 225 0.2480 0.1713 0.2756 8.03e-14
19 6iun:B 692 184 0.2120 0.0766 0.2880 3.29e-13 6iun:A
20 2vss:B 247 202 0.2160 0.2186 0.2673 4.69e-13 6l3p:A, 6l3p:B, 2vss:D, 2vss:E, 2vss:F, 2vsu:A, 2vsu:B, 2vsu:D, 2vsu:E, 2vsu:F
21 4izc:B 266 202 0.2400 0.2256 0.2970 8.80e-12 4izc:A, 4izd:A, 4izd:B
22 4jvt:A 257 185 0.2480 0.2412 0.3351 2.95e-10 4omr:A
23 6p5u:E 246 189 0.2000 0.2033 0.2646 8.83e-09 6p5u:A, 6p5u:B, 6p5u:C, 6p5u:D, 6p5u:F
24 6ysw:A 707 227 0.2360 0.0835 0.2599 2.85e-08
25 2uzf:A 260 201 0.2040 0.1962 0.2537 1.29e-07
26 4i42:A 285 210 0.2280 0.2000 0.2714 3.64e-07 4els:A, 4els:B, 4els:C, 4els:D, 4els:E, 4els:F, 4elw:A, 4elw:B, 4elw:C, 4elw:D, 4elw:E, 4elw:F, 4elx:A, 4elx:B, 4elx:C, 4elx:D, 4elx:F, 3h02:A, 3h02:B, 3h02:C, 3h02:D, 3h02:E, 3h02:F, 4i42:F, 4i42:B, 4i42:D, 4i42:C, 4i42:E, 4i42:G, 4i42:L, 4i42:H, 4i42:J, 4i42:I, 4i42:K, 3t88:A, 3t88:E, 3t88:B, 3t88:F, 3t88:C, 3t88:D
27 4hdt:A 340 178 0.2000 0.1471 0.2809 1.37e-06
28 3zwa:A 727 208 0.2280 0.0784 0.2740 2.56e-06 5mgb:A, 5mgb:B, 5omo:A, 5omo:B, 2x58:A, 2x58:B, 6z5f:AAA, 6z5f:BBB, 6z5o:AAA, 6z5v:AAA, 6z5v:BBB, 6zib:AAA, 6zib:BBB, 6zic:AAA, 6zic:BBB, 3zw9:A, 3zw9:B, 3zwa:B, 3zwb:A, 3zwb:B, 3zwc:A, 3zwc:B
29 1wdl:A 715 224 0.2160 0.0755 0.2411 1.36e-05 2d3t:A, 2d3t:B, 1wdk:A, 1wdk:B, 1wdl:B, 1wdm:A, 1wdm:B
30 1jxz:B 269 190 0.1880 0.1747 0.2474 2.38e-05 1jxz:A, 1jxz:C, 1nzy:A, 1nzy:B, 1nzy:C
31 5kag:D 423 236 0.2600 0.1537 0.2754 4.40e-05 5kag:A, 5kag:B, 5kag:C, 5kag:E, 5kag:F, 5kag:G, 5kag:H, 5kag:I, 5kag:J, 5kag:K, 5kag:L, 5kah:A, 5kah:B, 5kah:C, 5kah:D, 5kah:E, 5kah:F, 5kah:G, 5kah:H, 5kah:I, 5kah:J, 5kah:K, 5kah:L, 5kaj:A, 5kaj:B, 5kaj:C, 5kaj:D, 5kaj:E, 5kaj:F, 5kaj:G, 5kaj:H, 5kaj:I, 5kaj:J, 5kaj:K, 5kaj:L, 2np9:A, 2np9:B, 2np9:C, 2pg8:A, 2pg8:B, 2pg8:C, 4ylh:A, 4ylh:B, 4ylh:C, 4ylh:D, 4ylh:E, 4ylh:F, 4ylh:G, 4ylh:H, 4ylh:I, 4ylh:J, 4ylh:K, 4ylh:L
32 1ef9:A 261 179 0.1800 0.1724 0.2514 6.23e-05 6n92:A, 6n92:B, 6n92:C, 6n92:D, 6n92:E, 6n92:F, 6n93:A, 6n93:B, 6n93:C, 6n93:D, 6n93:E, 6n93:F, 6n94:A, 6n94:B, 6n94:C, 6n94:D, 6n94:E, 6n94:F, 6n95:A, 6n95:B, 6n95:C, 6n95:D, 6n95:E, 6n95:F, 6n96:A, 6n96:B, 6n96:C, 6n96:D, 6n96:E, 6n96:F, 6n97:A, 6n97:B, 6n97:C, 6n97:D, 6n97:E, 6n97:F
33 7xwt:B 277 239 0.2200 0.1986 0.2301 6.77e-05 7xwv:A, 7xwv:B
34 4i4z:A 275 217 0.2240 0.2036 0.2581 6.98e-05 4eml:A, 4eml:B, 4eml:C, 4eml:D, 4eml:E, 4eml:F, 4i4z:F, 4i4z:B, 4i4z:D, 4i4z:C, 4i4z:E, 4i4z:G, 4i4z:H, 4i4z:I, 4i52:A, 4i52:B, 4i52:C, 4i52:D, 4i52:E, 4i52:F, 4i52:G, 4i52:H, 4i52:I
35 6tnm:A 719 85 0.1000 0.0348 0.2941 1.01e-04
36 4qii:B 301 250 0.2440 0.2027 0.2440 0.002 1q51:B, 4qii:A, 4qii:F, 4qii:E, 4qii:C, 4qii:D, 4qii:G, 4qii:L, 4qii:H, 4qii:K, 4qii:I, 4qii:J, 4qij:A, 4qij:F, 4qij:B, 4qij:E, 4qij:C, 4qij:D, 4qij:G, 4qij:K, 4qij:H, 4qij:J, 4qij:I, 4qij:L
37 4fnb:A 232 80 0.1120 0.1207 0.3500 0.017 4fn8:A, 4fnd:A
38 1rjn:B 275 240 0.2120 0.1927 0.2208 0.019 1q51:A, 1q51:C, 1q51:D, 1q51:E, 1q51:F, 1q51:G, 1q51:H, 1q51:I, 1q51:J, 1q51:K, 1q51:L, 1rjm:A, 1rjm:B, 1rjm:C, 1rjn:A, 1rjn:C, 3t8a:B, 3t8a:C
39 1sg4:B 258 202 0.2000 0.1938 0.2475 0.17
40 3qur:A 249 63 0.0800 0.0803 0.3175 0.32 3qun:A
41 3vr1:A 516 55 0.0600 0.0291 0.2727 0.59 3vqt:A, 3vqt:B, 3vqt:C, 3vqt:D, 3vr1:B, 3vr1:C, 3vr1:D
42 1xx4:A 254 172 0.1560 0.1535 0.2267 1.1
43 8oqs:B 735 118 0.1200 0.0408 0.2542 1.2 4b3i:A, 4b3i:B, 4b3j:A, 4b3j:B, 7o4s:A, 7o4s:B, 7o4t:A, 7o4t:B, 7o4u:A, 7o4u:B, 7o4v:B, 7o4v:A, 8opu:A, 8opu:B, 8opv:A, 8opv:B, 8oql:A, 8oql:B, 8oqn:A, 8oqn:B, 8oqo:A, 8oqo:B, 8oqp:A, 8oqp:B, 8oqq:A, 8oqq:B, 8oqr:A, 8oqr:B, 8oqs:A, 8oqt:B, 8oqt:A, 8oqu:A, 8oqu:B, 8oqv:A, 8oqv:B, 8pf8:A, 8pf8:B
44 6eqo:A 1804 179 0.1880 0.0261 0.2626 2.6 6eqo:B
45 6slf:A 398 109 0.1400 0.0879 0.3211 3.5 6slf:B, 6slf:C, 6slf:D
46 3h4l:B 344 32 0.0560 0.0407 0.4375 4.1 3h4l:A
47 9bkd:a 99 54 0.0600 0.1515 0.2778 5.1 7a01:E3, 7a09:u, 5a2q:K, 5aj0:BK, 9bdl:AS10, 9bdn:AS10, 9bdp:AS10, 8bhf:L3, 9bln:a, 8btk:Aj, 7cpu:SK, 7cpv:SK, 4d5l:K, 4d61:K, 6d90:LL, 6d9j:LL, 9f1b:Aj, 9f1c:Aj, 9f1d:Aj, 6fec:t, 5flx:K, 6g51:K, 6g53:K, 6g5h:K, 6g5i:K, 8g5y:SK, 8g5z:SK, 8g60:SK, 8g61:SK, 8g6j:SK, 8glp:SK, 6gz3:BK, 6gz4:BK, 6gz5:BK, 6hcf:L1, 6hcj:L2, 6hcm:L1, 6hcq:L2, 8ifd:2u, 8ife:2u, 6ip5:2u, 6ip6:2u, 6ip8:2u, 3j7p:SK, 3j7r:SK, 3jag:KK, 3jah:KK, 3jai:KK, 3jaj:SK, 3jan:SK, 8jdj:7, 8jdk:7, 8jdl:7, 8jdm:7, 7jqb:L, 7jqc:L, 5k0y:t, 8k2c:SK, 7k5i:K, 4kzx:K, 4kzy:K, 4kzz:K, 5lks:SK, 7ls1:v2, 7ls2:v2, 5lzs:KK, 5lzt:KK, 5lzu:KK, 5lzv:KK, 5lzw:KK, 5lzx:KK, 5lzy:KK, 5lzz:KK, 7mdz:KK, 6mtb:KK, 6mtc:KK, 6mtd:KK, 6mte:KK, 7nwg:L2, 7nwh:KK, 7nwi:KK, 7o7y:Aj, 7o7z:Aj, 7o80:Aj, 7o81:Aj, 5oa3:K, 6ole:SK, 6olf:SK, 6olg:BK, 6oli:SK, 6olz:BK, 6om0:SK, 6om7:SK, 7oya:K2, 7oyb:K2, 7oyc:K2, 7oyd:KK, 8oz0:i, 8p03:M, 8p09:M, 8p2k:Aj, 6p4g:L, 6p4h:L, 6p5i:L, 6p5j:L, 6p5k:L, 6p5n:L, 8pj1:a, 8pj2:a, 8pj3:a, 8pj4:a, 8pj5:a, 8pj6:a, 8ppk:K, 8ppl:AK, 8q7z:Aj, 8q87:Aj, 7qgg:SK, 8qoi:SK, 7qp6:a, 7qp7:a, 7qvp:SK, 7qvp:RK, 6qzp:SK, 7r4x:K, 6r5q:SS, 6r6g:SS, 6r6p:SS, 6r7q:SS, 8scb:KK, 6sgc:L1, 7syg:L, 7syh:L, 7syi:L, 7syj:L, 7syk:L, 7syl:L, 7sym:L, 7syn:L, 7syo:L, 7syp:L, 7syq:L, 7syr:L, 7sys:L, 7syt:L, 7syu:L, 7syv:L, 7syw:L, 7syx:L, 5t2c:Av, 8t4s:K, 7toq:AS10, 7tor:AS10, 7tql:M, 7ucj:KK, 7uck:KK, 4ug0:SK, 4ujc:CK, 4ujd:CK, 4uje:BK, 4v6x:AK, 5vyc:K1, 5vyc:K2, 5vyc:K3, 5vyc:K4, 5vyc:K5, 5vyc:K6, 6w2s:L, 6w2t:L, 6xa1:SK, 7xnx:SK, 7xny:SK, 8xsx:SK, 8xsy:SK, 8xsz:SK, 8xxl:SK, 8xxm:SK, 8xxn:SK, 6y0g:SK, 8y0w:SK, 8y0x:SK, 6y2l:SK, 6y57:SK, 6yal:M, 6yam:M, 6yan:M, 6ybs:a, 8yoo:SK, 8yop:SK, 6z6l:SK, 6z6m:SK, 6z6n:SK, 7zjw:SV, 7zjx:SV, 6zlw:M, 6zm7:SK, 6zme:SK, 6zmi:SK, 6zmo:SK, 6zmt:M, 6zmw:a, 6zn5:M, 6zoj:K, 6zol:K, 6zon:u, 6zp4:u, 6zuo:K, 6zv6:K, 6zvh:K, 6zvj:u, 6zvk:E3, 6zxd:K, 6zxe:K, 6zxf:K, 6zxg:K, 6zxh:K
48 207l:A 130 18 0.0360 0.0692 0.5000 7.4 208l:A, 1d6q:A, 1hnl:A, 1i22:A, 1i22:B, 1i22:C, 1i22:D, 3lhm:A, 5lsh:A, 1re2:A, 1rem:A, 1rez:A, 1ubz:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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