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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADKMVPRFLLLSAASMLVMRYWFWRLFETLPPP
ALDASFLFALLLFAVETFSISIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAAAKNMIYPARL
RTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCRELGVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPS
RDFLARTVGYFVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRWGGAFFCGSAAVLRRRALDEA
GGFAGETITEDAETALEIHSRGWKSLYIDRAMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLN
SMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLVQNALFARQRWPLVSEVYEVAQAPYLARAIV
TTLLRPRSARFAVTAKDETLSENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLNVLLVGFALRA
VAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDASTSGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERM
VRGRIRSARREGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHGMARILWMAAASLPKTARDFM
DEPARRRRRHEEPKEKQAHLLAFGTDF

The query sequence (length=747) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4hg6:A 747 747 1.0000 1.0000 1.0000 0.0 5eiy:A, 5ej1:A, 5ejz:A, 4p00:A, 4p02:A
2 6yv8:A 346 233 0.0830 0.1792 0.2661 1.56e-10 6yv8:B, 6yv9:A, 6yv9:B
3 8g27:I 720 339 0.1044 0.1083 0.2301 4.88e-08 8g27:C, 8g27:D, 8g2j:C, 8g2j:D, 8g2j:I, 6wlb:A, 6wlb:C, 6wlb:B
4 7d5k:A 727 303 0.0977 0.1004 0.2409 1.58e-07 7d5k:B, 7d5k:C
5 7ck2:A 352 184 0.0616 0.1307 0.2500 0.24 7ck2:B
6 5tze:C 349 131 0.0402 0.0860 0.2290 1.1 5tze:E, 5tzj:C, 5tzj:A, 5tzk:C
7 1xmt:A 95 42 0.0187 0.1474 0.3333 1.4 2il4:A, 2q4y:A
8 8gkf:G 197 43 0.0201 0.0761 0.3488 2.4
9 8ujg:A 530 45 0.0201 0.0283 0.3333 2.7 8uhz:A, 8ui1:A, 8ui6:A, 8uje:A, 8ujf:A, 8ujf:B, 8ujg:B, 8ujh:A
10 7b9v:H 453 53 0.0214 0.0353 0.3019 3.6 7dco:V, 5gm6:Z, 5gmk:Z, 6j6g:Z, 6j6h:Z, 6j6n:Z, 6j6q:Z, 5wsg:Z, 5ylz:S
11 7y1u:A 723 82 0.0268 0.0277 0.2439 3.6
12 2hps:A 184 46 0.0228 0.0924 0.3696 3.7 2hq8:A, 2hq8:B
13 2z86:C 603 47 0.0201 0.0249 0.3191 9.8 2z86:A, 2z86:B, 2z86:D, 2z87:A, 2z87:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218