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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VVPLKRIDKIRWEIPKFDKRMRVPGRVYADEVLLEKMKNDRTLEQATNVAMLPGIYKYSIVMPDGHQGYGFPIGGVAAFD
VKEGVISPGGIGYDINCGVRLIRTNLTEKEVRPRIKQLVDTLFKNVPSGVRIKLHWTQIDDVLVDGAKWAVDNGYGWERD
LERLEEGGRMEGADPEAVSQRAKQRGAPQLGSLGSGNHFLEVQVVDKIFDPEVAKAYGLFEGQVVVMVHTGSRGLGHQVA
SDYLRIMERAIRKYRIPWPDRELVSVPFQSEEGQRYFSAMKAAANFAWANRQMITHWVRESFQEVFKQDPEGDLGMDIVY
DVAHNIGKVEEHEVDGKRVKVIVHRKGATRAFPPGHEAVPRLYRDVGQPVLIPGSMGTASYILAGTEGAMKETFGSTCHG
AGRVLSRKAATRQYRGDRIRQELLNRGIYVRAASMRVVAEEAPGAYKNVDNVVKVVSEAGIAKLVARMRPIGVAKGAAAL
E

The query sequence (length=481) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4dwr:B 486 485 1.0000 0.9897 0.9918 0.0 8dc9:A, 8dc9:B, 8dca:A, 8dca:B, 8dcb:A, 8dcb:B, 8dcd:A, 8dcd:B, 8dcf:A, 8dcf:B, 8dcg:A, 8dcg:B, 4dwq:A, 4dwq:B, 4dwr:A, 4dwr:C, 4isj:A, 4isj:B, 4isz:A, 4isz:B, 4it0:A, 4it0:B, 7lfq:A, 1uc2:A, 1uc2:B
2 8odp:A 505 495 0.4990 0.4752 0.4848 4.20e-160 8btt:A, 8odo:A, 8odo:C, 8odo:E, 8odo:G, 8odp:C, 8odp:E, 8odp:G, 7p3b:A, 7p3b:B
3 8btt:B 484 487 0.4802 0.4773 0.4743 9.12e-150
4 8ryo:E 243 106 0.0686 0.1358 0.3113 0.013 2iam:D, 2ian:E, 2ian:J, 2ian:O, 2ian:T, 7qpj:B, 8rym:E, 8ryn:E
5 3btp:A 386 87 0.0582 0.0725 0.3218 0.20
6 6qi8:A 317 119 0.0728 0.1104 0.2941 1.7 7aho:B, 6qi8:B, 6qi9:A, 6qi9:B
7 3fwn:A 467 103 0.0437 0.0450 0.2039 2.1 3fwn:B, 2zya:A, 2zya:B, 2zyd:A, 2zyd:B
8 4zoh:A 701 232 0.1102 0.0756 0.2284 3.5
9 7phr:B 285 57 0.0374 0.0632 0.3158 6.7 5euo:H, 5euo:F, 5hhm:E, 5hhm:J, 5hho:E, 5isz:E, 5jhd:E, 5jhd:J, 6mtm:E, 7n6e:J, 7n6e:H, 5nht:B, 5nqk:B, 1oga:E, 2vlj:E, 2vlk:E, 2vlr:E, 2vlr:J
10 2zxr:A 616 109 0.0561 0.0438 0.2477 7.6
11 9ema:A 326 117 0.0707 0.1043 0.2906 7.7 7aho:A, 7aho:C, 2c9o:C, 9ema:B, 9ema:C, 9emc:A, 9emc:B, 9emc:C, 6fo1:A, 6fo1:B, 6fo1:C, 6k0r:A, 6k0r:B, 6k0r:C, 6k0r:G, 6k0r:H, 6k0r:I, 7p6x:A, 7p6x:B, 7p6x:C, 6qi8:C, 6qi9:C, 2xsz:A, 2xsz:B, 2xsz:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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