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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTN
FHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGS
TLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHG

The query sequence (length=214) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7d4i:SC 242 214 1.0000 0.8843 1.0000 1.43e-159 7a1g:Q, 7ajt:DA, 7aju:DA, 7b7d:Q, 8bn3:S1, 8bqd:Q, 8bqx:Q, 8c00:Q, 8c01:Q, 8cah:Q, 8cas:Q, 8cbj:B, 8ccs:e, 8cdl:e, 8cdr:e, 8ceh:e, 8cf5:e, 8cg8:e, 8cgn:e, 8civ:e, 8cku:e, 8cmj:e, 7d5t:SC, 7d63:SC, 5dat:S1, 5dat:s1, 5dc3:S1, 5dc3:s1, 5dge:S1, 5dge:s1, 5dgf:S1, 5dgf:s1, 5dgv:S1, 5dgv:s1, 6eml:Q, 8eub:BB, 8evp:BB, 8evq:BB, 8evr:BB, 8evs:BB, 8evt:BB, 8ewb:BB, 8ewc:BB, 6fai:B, 5fci:S1, 5fci:s1, 5fcj:S1, 5fcj:s1, 6fyx:B, 6fyy:B, 6gq1:r, 6gqb:r, 6gqv:r, 6gsm:B, 6gsn:B, 6hhq:s1, 6hhq:C, 5i4l:S1, 5i4l:s1, 6i7o:Q, 6i7o:Qb, 8i7j:B, 5it7:B, 5it9:B, 3j6x:S1, 3j6y:S1, 3j77:S1, 3j78:S1, 3j80:B, 3j81:B, 3jam:B, 3jap:B, 5juo:YA, 5jup:YA, 5jus:YA, 5jut:YA, 5juu:YA, 8k2d:SB, 8k82:SB, 6ke6:SC, 5ll6:Q, 6lqp:SC, 6lqq:SC, 6lqr:SC, 6lqs:SC, 6lqt:SC, 5lyb:S1, 5lyb:s1, 5m1j:B2, 5mc6:Q, 5mei:s1, 5mei:C, 7mpi:BB, 7mpj:BB, 7n8b:BB, 5ndg:S1, 5ndg:s1, 5ndv:S1, 5ndv:s1, 5ndw:S1, 5ndw:s1, 7nrc:SQ, 7nrd:SQ, 5obm:S1, 5obm:s1, 5on6:s1, 5on6:C, 7osa:eS1, 7osm:eS1, 6q8y:Q, 6rbd:B, 6rbe:B, 7rr5:SB, 8rw1:B, 6s47:BC, 8s8d:B, 8s8e:B, 8s8f:B, 8s8g:B, 8s8h:B, 8s8i:B, 8s8j:B, 6snt:B, 6sv4:Q, 6sv4:Qb, 6sv4:Qc, 6t4q:SB, 6t7i:SB, 6t7t:SB, 6t83:Ba, 6t83:c, 5tbw:s1, 5tbw:C, 6tb3:Q, 5tga:S1, 5tga:s1, 5tgm:S1, 5tgm:s1, 6tnu:Q, 4u3m:S1, 4u3m:s1, 4u3n:S1, 4u3n:s1, 4u3u:S1, 4u3u:s1, 4u4n:S1, 4u4n:s1, 4u4o:S1, 4u4o:s1, 4u4q:S1, 4u4q:s1, 4u4r:S1, 4u4r:s1, 4u4u:S1, 4u4u:s1, 4u4y:S1, 4u4y:s1, 4u4z:S1, 4u4z:s1, 4u50:S1, 4u50:s1, 4u51:S1, 4u51:s1, 4u52:S1, 4u52:s1, 4u53:S1, 4u53:s1, 4u55:S1, 4u55:s1, 4u56:S1, 4u56:s1, 4u6f:S1, 4u6f:s1, 4uer:4, 6uz7:B, 4v88:AB, 4v88:CB, 4v8y:AB, 4v8z:AB, 4v92:BB, 6woo:BB, 7wtl:SB, 7wtm:SB, 7wtn:SB, 7wto:SB, 7wtp:SB, 7wtq:SB, 7wtr:SB, 5wyj:SC, 5wyk:SC, 6xiq:r, 6xir:r, 8y0u:SB, 6y7c:B, 6z6j:SB, 6z6k:SB, 6zce:C, 7zpq:AB, 6zqa:DA, 6zqb:DA, 6zqc:DA, 6zqd:DA, 6zqe:DA, 6zqf:DA, 6zqg:DA, 7zrs:AB, 6zu9:Q, 7zuw:AB, 7zux:DB, 6zvi:j, 7zw0:sQ
2 8c3a:D 214 214 0.7850 0.7850 0.7850 1.05e-131 8c3a:CO, 8cq7:D, 8cq7:CO, 8cqw:D, 8cqw:CO, 8cre:D, 8cre:CO, 8oeq:D, 8oeq:CO, 7pzy:C, 7q08:C, 7q0f:C, 7q0p:C, 7q0r:C, 8q5i:C
3 7olc:SB 232 214 0.7336 0.6767 0.7336 7.18e-120 7old:SB, 8oo0:SB, 5oql:l, 7r81:C2, 6rxt:Ca, 6rxu:Ca, 6rxv:Ca, 6rxx:Ca, 7z3n:SB, 7z3o:SB
4 8jiw:BB 213 211 0.6262 0.6291 0.6351 1.12e-99 8ip8:bb, 8ip9:bb, 8ipa:bb, 8ipb:bb, 8r6f:B, 4v7e:BB
5 8auv:F 216 212 0.6215 0.6157 0.6274 6.69e-99 8b2l:F1, 7qix:F, 7qiz:v
6 7mq8:NM 233 214 0.5841 0.5365 0.5841 1.64e-92 7a01:V3, 7a09:p, 5a2q:B, 5aj0:BB, 9bdl:AS01, 9bdn:AS01, 9bdp:AS01, 8bhf:C3, 9bkd:O, 9bln:O, 8btk:Aa, 7cpu:SB, 7cpv:SB, 4d5l:B, 4d61:B, 6d90:CC, 6d9j:CC, 9f1b:Aa, 9f1c:Aa, 9f1d:Aa, 6fec:i, 5flx:B, 6g18:B, 6g4s:B, 6g4w:B, 6g51:B, 6g53:B, 6g5h:B, 6g5i:B, 8g5y:SB, 8g5z:SB, 8g60:SB, 8g61:SB, 8g6j:SB, 8glp:SB, 6gz3:BB, 6gz4:BB, 6gz5:BB, 6hcf:C1, 6hcj:C2, 6hcm:C1, 6hcq:C2, 8ifd:2o, 8ife:2o, 6ip5:2o, 6ip6:2o, 6ip8:2o, 3j7p:SB, 3j7r:SB, 3jag:BB, 3jah:BB, 3jai:BB, 3jaj:SB, 3jan:SB, 8jdj:y, 8jdk:y, 8jdl:y, 8jdm:y, 7jqb:C, 7jqc:C, 5k0y:i, 8k2c:SB, 7k5i:B, 4kzx:B, 4kzy:B, 4kzz:B, 5lks:SB, 7ls1:p2, 7ls2:p2, 5lzs:BB, 5lzt:BB, 5lzu:BB, 5lzv:BB, 5lzw:BB, 5lzx:BB, 5lzy:BB, 5lzz:BB, 7mdz:BB, 7mq9:NM, 7mqa:NM, 6mtb:BB, 6mtc:BB, 6mtd:BB, 6mte:BB, 7nwg:C2, 7nwh:BB, 7nwi:BB, 7o7y:Aa, 7o7z:Aa, 7o80:Aa, 7o81:Aa, 5oa3:B, 6ole:SB, 6olf:SB, 6olg:BB, 6oli:SB, 6olz:BB, 6om0:SB, 6om7:SB, 7oya:B2, 7oyb:B2, 7oyc:B2, 7oyd:BB, 8oz0:P, 8p03:D, 8p09:D, 8p2k:Aa, 6p4g:C, 6p4h:C, 6p5i:C, 6p5j:C, 6p5k:C, 6p5n:C, 8pj1:O, 8pj2:O, 8pj3:O, 8pj4:O, 8pj5:O, 8pj6:O, 8ppk:B, 8ppl:AB, 8q7z:Aa, 8q87:Aa, 7qgg:SB, 8qoi:SB, 7qp6:O, 7qp7:O, 7qvp:SB, 7qvp:RB, 6qzp:SB, 7r4x:B, 6r5q:u, 6r6g:u, 6r6p:u, 6r7q:u, 8rg0:O, 8scb:BB, 6sgc:C1, 7syg:C, 7syh:C, 7syi:C, 7syj:C, 7syk:C, 7syl:C, 7sym:C, 7syn:C, 7syo:C, 7syp:C, 7syq:C, 7syr:C, 7sys:C, 7syt:C, 7syu:C, 7syv:C, 7syw:C, 7syx:C, 5t2c:Ap, 8t4s:B, 7toq:AS01, 7tor:AS01, 7tql:C, 7ucj:BB, 7uck:BB, 4ug0:SB, 4ujc:CB, 4ujd:CB, 4uje:BB, 4v6x:AB, 5vyc:B1, 5vyc:B2, 5vyc:B3, 5vyc:B4, 5vyc:B5, 5vyc:B6, 6w2s:C, 6w2t:C, 7wts:B, 7wtt:B, 7wtu:B, 7wtv:B, 7wtw:B, 7wtx:B, 7wtz:B, 7wu0:B, 6xa1:SB, 7xnx:SB, 7xny:SB, 8xsx:SB, 8xsy:SB, 8xsz:SB, 8xxl:SB, 8xxm:SB, 8xxn:SB, 6y0g:SB, 8y0w:SB, 8y0x:SB, 6y2l:SB, 6y57:SB, 6yal:D, 6yam:D, 6yan:D, 6ybw:O, 8yoo:SB, 8yop:SB, 6z6l:SB, 6z6m:SB, 6z6n:SB, 7zjw:SM, 7zjx:SM, 6zlw:C, 6zm7:SB, 6zme:SB, 6zmi:SB, 6zmo:SB, 6zmt:C, 6zmw:O, 6zn5:C, 6zoj:B, 6zok:B, 6zon:p, 6zp4:p, 6zuo:B, 6zv6:B, 6zvh:B, 6zvj:p, 6zvk:V3, 6zxd:B, 6zxe:B, 6zxf:B, 6zxg:B, 6zxh:B
7 5xxu:B 212 212 0.5794 0.5849 0.5849 8.42e-88
8 4v6w:AB 220 216 0.5514 0.5364 0.5463 1.51e-84 6xu6:AB, 6xu7:AB, 6xu8:AB
9 9bh5:AB 210 211 0.5561 0.5667 0.5640 5.91e-84 9cai:AB
10 6zj3:SA 221 213 0.5140 0.4977 0.5164 7.29e-75
11 3j7a:B 210 209 0.5140 0.5238 0.5263 1.47e-74 3jbn:B, 3jbo:B, 3jbp:B, 6okk:B, 8tpu:SB
12 4bts:B4 221 218 0.5000 0.4842 0.4908 2.62e-72 4bts:A4, 4bts:C4, 4bts:D4, 5jpq:o, 4v5o:A4, 4v5o:B4
13 8ova:A0 220 212 0.4346 0.4227 0.4387 2.94e-64 8ove:A0, 4v8m:A0
14 8rxh:SA 244 214 0.4159 0.3648 0.4159 2.44e-62 8a3w:SA, 8a98:SA, 6az1:A, 8ovj:SA, 8rxx:SA, 5t2a:0
15 7ase:W 217 215 0.4206 0.4147 0.4186 5.59e-61 5opt:W
16 6rm3:SB0 210 201 0.3925 0.4000 0.4179 1.32e-49
17 7qep:S1 209 198 0.3505 0.3589 0.3788 3.79e-46
18 6zu5:SB0 196 200 0.3785 0.4133 0.4050 1.46e-44
19 8br8:SD 231 213 0.3505 0.3247 0.3521 1.49e-39 8brm:SD, 8bsi:SD, 8bsj:SD, 8btd:SD, 8btr:SD, 8fvy:B, 8g4s:B, 7pwf:B, 7pwo:B1
20 5xyi:B 219 199 0.3271 0.3196 0.3518 3.88e-36
21 8p5d:SB0 204 191 0.3224 0.3382 0.3613 2.99e-35 8p60:SB0, 8p60:RB0, 7qca:SB0
22 5jb3:A 190 203 0.3084 0.3474 0.3251 2.42e-26 5jbh:A, 6sw9:A, 6swc:A, 6swd:A, 4v4n:BA, 4v6u:AA, 7zag:A, 7zah:A, 7zai:A, 7zhg:A
23 6skf:Ad 190 204 0.2944 0.3316 0.3088 4.37e-25 6skg:Ad, 6th6:Ad
24 6tmf:D 184 202 0.2664 0.3098 0.2822 1.14e-22
25 8hkx:S3AE 189 202 0.3084 0.3492 0.3267 1.30e-22 8hky:S3AE, 8hkz:S3AE, 8hl1:S3AE, 8hl2:S3AE, 8hl3:S3AE, 8hl4:S3AE, 8hl5:S3AE, 8wkp:S3AE, 8wq2:S3AE, 8wq4:S3AE
26 3vc6:A 420 50 0.0654 0.0333 0.2800 0.22
27 6vsh:C 320 82 0.0701 0.0469 0.1829 0.38 3gke:C, 3gl0:C, 3gl2:C
28 3gob:A 342 82 0.0701 0.0439 0.1829 0.44 3gb4:A, 3gb4:B, 3gb4:C, 3gke:A, 3gke:B, 3gl0:A, 3gl0:B, 3gl2:A, 3gl2:B, 3gob:B, 3gob:C, 3gte:A, 3gte:B, 3gte:C, 3gts:A, 3gts:B, 3gts:C, 6vsh:A, 6vsh:B
29 6xgw:B 356 38 0.0607 0.0365 0.3421 1.4 6xg8:B, 6xgx:B
30 6xgx:A 402 38 0.0607 0.0323 0.3421 1.5 6xg8:A, 6xgw:A
31 1lfw:A 468 113 0.1355 0.0620 0.2566 2.7
32 4xau:C 374 36 0.0607 0.0348 0.3611 6.5
33 2r8q:A 335 40 0.0654 0.0418 0.3500 6.7 2r8q:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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