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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VTGAVSSVNMRRFQRVPKVSGFSAKVTKKNVNKALDKADMFFAKSVTMEGKAAAIPYGVYGIQCMEGSAKGMAHEKRAMA
LSAAFRMNQRSAAEKTGAMYENRRLALILAQNDHQEKQYIKYPKLAAAALMASTEVTRACQRYAVPESIEEEFLAASVDK
VNKMRGTTASGVYKSSCVEGNAKGQAEQARVAALAVAFRSAQKSASQFAAERYAQSKYGRDLFSSTHFEEGYANTYPAMA
AAKRASSYGY

The query sequence (length=250) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ezx:BB 250 250 1.0000 1.0000 1.0000 0.0 7ezx:yJ, 7ezx:yL, 7ezx:BM, 6kgx:B8, 6kgx:BA, 6kgx:yE, 6kgx:yG, 7y4l:yF, 7y4l:BH, 7y4l:B4, 7y4l:y8, 7y5e:yF, 7y5e:BJ, 7y5e:yK, 7y5e:BM, 7y7a:B3, 7y7a:y6, 7y7a:BC, 7y7a:yQ, 7y7a:yT, 7y7a:BV, 7y7a:yb, 7y7a:Bp
2 7ezx:A1 257 240 0.5520 0.5370 0.5750 8.83e-85 7ezx:A7, 7ezx:A9, 7ezx:AF, 7ezx:AI, 7ezx:AK, 6kgx:A2, 6kgx:Y3, 6kgx:A6, 6kgx:A7, 6kgx:A9, 6kgx:AB, 6kgx:YD, 6kgx:AF, 6kgx:AI, 6kgx:AJ, 7y4l:AB, 7y4l:AC, 7y4l:AD, 7y4l:AE, 7y4l:AJ, 7y4l:YK, 7y4l:Y1, 7y4l:A2, 7y4l:A5, 7y4l:A6, 7y5e:YA, 7y5e:AD, 7y5e:AE, 7y5e:AG, 7y5e:AH, 7y5e:AO, 7y5e:AQ, 7y5e:A1, 7y5e:A4, 7y5e:Y7, 7y7a:A1, 7y7a:A2, 7y7a:A4, 7y7a:Y5, 7y7a:A8, 7y7a:YD, 7y7a:AF, 7y7a:AI, 7y7a:AK, 7y7a:AM, 7y7a:AP, 7y7a:AR, 7y7a:AS, 7y7a:Ac, 7y7a:Ae, 7y7a:Yg, 7y7a:Yi, 7y7a:Aj, 7y7a:Al, 7y7a:An
3 7ezx:AB 238 233 0.4720 0.4958 0.5064 5.25e-66 7ezx:wJ, 7ezx:xJ, 7ezx:wL, 7ezx:xL, 7ezx:AM, 6kgx:A8, 6kgx:AA, 6kgx:wE, 6kgx:xE, 6kgx:wG, 6kgx:xG, 7y4l:wF, 7y4l:AH, 7y4l:A4, 7y4l:w8, 7y4l:x8, 7y4l:xF, 7y5e:wF, 7y5e:AJ, 7y5e:wK, 7y5e:AM, 7y5e:xF, 7y5e:xK, 7y7a:A3, 7y7a:w6, 7y7a:x6, 7y7a:AC, 7y7a:wQ, 7y7a:xQ, 7y7a:wT, 7y7a:xT, 7y7a:AV, 7y7a:wb, 7y7a:xb, 7y7a:Ap
4 5y6p:C2 245 245 0.4000 0.4082 0.4082 5.97e-50 5y6p:D2, 5y6p:c3, 5y6p:d3, 5y6p:44, 5y6p:Z5, 5y6p:e8, 5y6p:c8, 5y6p:d8, 5y6p:e9, 5y6p:c9, 5y6p:d9, 5y6p:T8, 5y6p:Y9, 5y6p:aZ, 5y6p:bZ
5 5y6p:lz 251 212 0.3640 0.3625 0.4292 1.59e-42 5y6p:ly, 5y6p:hY, 5y6p:hZ
6 7y4l:MI 275 217 0.3360 0.3055 0.3871 1.10e-36 7ezx:MA, 7ezx:MG, 7ezx:MN, 7ezx:MQ, 6kgx:M1, 6kgx:21, 6kgx:M4, 6kgx:24, 7y4l:ZI, 7y4l:M9, 7y4l:Z9, 7y5e:Z9, 7y5e:M5, 7y5e:Z5, 7y5e:M9, 7y7a:MH, 7y7a:ZH, 7y7a:Ma, 7y7a:Mf, 7y7a:Za, 7y7a:Zf, 7y7a:Mh, 7y7a:Zh
7 7y4l:MI 275 95 0.1480 0.1345 0.3895 7.60e-12 7ezx:MA, 7ezx:MG, 7ezx:MN, 7ezx:MQ, 6kgx:M1, 6kgx:21, 6kgx:M4, 6kgx:24, 7y4l:ZI, 7y4l:M9, 7y4l:Z9, 7y5e:Z9, 7y5e:M5, 7y5e:Z5, 7y5e:M9, 7y7a:MH, 7y7a:ZH, 7y7a:Ma, 7y7a:Mf, 7y7a:Za, 7y7a:Zf, 7y7a:Mh, 7y7a:Zh
8 5y6p:eZ 309 211 0.3200 0.2589 0.3791 2.53e-28 5y6p:eY
9 5y6p:eZ 309 96 0.1160 0.0939 0.3021 0.054 5y6p:eY
10 5y6p:A2 277 213 0.3080 0.2780 0.3615 2.22e-27 5y6p:a3, 5y6p:34, 5y6p:Y5, 5y6p:b8, 5y6p:b9, 5y6p:U8, 5y6p:Z9, 5y6p:aY, 5y6p:bY, 5y6p:dw, 5y6p:dx, 5y6p:ey, 5y6p:ez
11 5y6p:gy 260 218 0.2600 0.2500 0.2982 1.78e-22 5y6p:gz
12 7lep:G 164 31 0.0480 0.0732 0.3871 2.0 7ldd:G, 7ldd:H, 7lde:G, 7lde:H, 7lep:H
13 5mtv:A 379 62 0.0520 0.0343 0.2097 6.5 5mvf:A
14 1z6o:A 212 50 0.0640 0.0755 0.3200 7.2 1z6o:E, 1z6o:L, 1z6o:B, 1z6o:D, 1z6o:K, 1z6o:C, 1z6o:H, 1z6o:I, 1z6o:F, 1z6o:G, 1z6o:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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