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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VSSHGYRRQTRNLFSQAFRKHGMPNTSTYLTQYAVGEYVDIKVNPAIHKGMPHKYYHGRTGIIKEVNRGSVIVLFNRILA
NKTVERKVIVGIEHIRKSKCQDEYLKRLEINKKIIEEAEKKGEVPVLFKRQPKGPKPAVEMLMNNIIELSYDKVES

The query sequence (length=156) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8p5d:LT0 156 156 1.0000 1.0000 1.0000 4.25e-114 8p60:LT0, 8p60:KT0, 7qca:LT0
2 6zu5:LT0 160 145 0.4487 0.4375 0.4828 1.29e-44
3 7qep:N1 159 152 0.4679 0.4591 0.4803 6.96e-42
4 4v3p:LU 164 159 0.4487 0.4268 0.4403 7.24e-42 8ip8:BA, 8ipa:BA, 8ipb:BA, 8jiv:CT, 4v7e:CT
5 8azw:J 163 156 0.4487 0.4294 0.4487 7.00e-41 8b2l:J3, 7qiw:V, 7qiz:V
6 8hfr:Tl 160 134 0.4038 0.3937 0.4701 5.41e-40 8aaf:G, 8agt:G, 8agu:G, 8agv:G, 8agw:G, 8agx:G, 8agz:G, 5apn:T, 5apo:T, 7azy:u, 7b7d:Lp, 8bip:LT, 8bjq:LT, 8bn3:N1, 8bqd:BJ, 8bqx:BJ, 7bt6:T, 7btb:T, 8ccs:F, 8cdl:F, 8cdr:F, 8ceh:F, 8cf5:F, 8cg8:F, 8cgn:F, 8civ:F, 8cku:F, 8cmj:F, 5dat:N1, 5dat:n1, 5dc3:N1, 5dc3:n1, 5dge:N1, 5dge:n1, 5dgf:N1, 5dgf:n1, 5dgv:N1, 5dgv:n1, 6elz:T, 8eub:AT, 8evp:AT, 8evq:AT, 8evr:AT, 8evs:AT, 8evt:AT, 8ewb:AT, 8ewc:AT, 5fci:N1, 5fci:n1, 5fcj:N1, 5fcj:n1, 6ft6:T, 5gak:V, 6gq1:T, 6gqb:T, 6gqv:T, 5h4p:T, 6hd7:V, 6hhq:2, 6hhq:CV, 5i4l:N1, 5i4l:n1, 6i7o:BJ, 6i7o:YJ, 5it7:TT, 3j6x:61, 3j6y:61, 3j77:71, 3j78:71, 3jct:T, 5jcs:T, 5juo:Y, 5jup:Y, 5jus:Y, 5jut:Y, 5juu:Y, 8k2d:LT, 8k82:LT, 5lyb:N1, 5lyb:n1, 5m1j:T5, 6m62:T, 5mc6:BJ, 5mei:2, 5mei:CV, 7mpi:AT, 7mpj:AT, 6n8j:T, 6n8k:T, 6n8l:T, 6n8m:g, 6n8n:g, 6n8o:g, 7n8b:AT, 7nac:T, 5ndg:N1, 5ndg:n1, 5ndv:N1, 5ndv:n1, 5ndw:N1, 5ndw:n1, 7nrc:LV, 7nrd:LV, 5obm:N1, 5obm:n1, 7of1:T, 7oh3:T, 7ohq:T, 7oht:T, 6oig:T, 5on6:2, 5on6:CV, 7osa:eL21, 7osm:eL21, 8p8m:QT, 8p8n:QT, 8p8u:QT, 8pfr:QT, 6q8y:BJ, 6qik:T, 6qt0:T, 6qtz:T, 7r7a:T, 6r84:V, 6r86:V, 6r87:V, 6ri5:T, 7rr5:LT, 6rzz:T, 6s05:T, 6s47:AV, 6snt:z, 6sv4:BJ, 6sv4:YJ, 6sv4:ZJ, 6t4q:LT, 5t62:g, 5t6r:g, 6t7i:LT, 6t7t:LT, 6t83:Ty, 6t83:E, 5tbw:2, 5tbw:CV, 6tb3:BJ, 5tga:N1, 5tga:n1, 5tgm:N1, 5tgm:n1, 6tnu:BJ, 7too:AL21, 7top:AL21, 4u3m:N1, 4u3m:n1, 4u3n:N1, 4u3n:n1, 4u3u:N1, 4u3u:n1, 4u4n:N1, 4u4n:n1, 4u4o:N1, 4u4o:n1, 4u4q:N1, 4u4q:n1, 4u4r:N1, 4u4r:n1, 4u4u:N1, 4u4u:n1, 4u4y:N1, 4u4y:n1, 4u4z:N1, 4u4z:n1, 4u50:N1, 4u50:n1, 4u51:N1, 4u51:n1, 4u52:N1, 4u52:n1, 4u53:N1, 4u53:n1, 4u55:N1, 4u55:n1, 4u56:N1, 4u56:n1, 4u6f:N1, 4u6f:n1, 7ug6:T, 7uoo:T, 7uqb:T, 7uqz:T, 6uz7:AT, 7v08:T, 4v4b:BQ, 4v6i:BU, 4v7f:T, 4v7h:BQ, 4v7r:BT, 4v7r:DT, 4v88:BT, 4v88:DT, 4v8t:T, 4v8y:BT, 4v8z:BT, 4v91:T, 6woo:T, 6xiq:T, 6xir:T, 8y0u:LT, 6ylg:T, 6ylh:T, 6ylx:T, 6yly:T, 7z34:T, 6z6j:LT, 6z6k:LT, 7zpq:BS, 7zrs:BS, 7zs5:BU, 7zuw:BS, 7zux:ES, 7zw0:LW
7 8eui:T 159 136 0.4038 0.3962 0.4632 3.22e-38 8eug:T
8 8c3a:2 159 134 0.3974 0.3899 0.4627 3.30e-37 8c3a:BO, 8cq7:2, 8cq7:BO, 8cqw:2, 8cqw:BO, 8cre:2, 8cre:BO, 8oeq:2, 8oeq:BO, 7pzy:2, 7q08:2, 7q0f:2, 7q0p:2, 7q0r:2, 8q5i:2
9 6rm3:LT0 159 143 0.3974 0.3899 0.4336 5.81e-37
10 4v8m:BU 158 122 0.3654 0.3608 0.4672 7.57e-37 8ova:BU, 8ove:BU
11 5xxb:S 154 138 0.3846 0.3896 0.4348 8.20e-37
12 4v6w:CT 158 138 0.3974 0.3924 0.4493 1.67e-36 6xu6:CT, 6xu7:CT, 6xu8:CT
13 7olc:LT 158 148 0.3974 0.3924 0.4189 1.73e-35 8i9p:LT, 8i9r:LT, 8i9t:LT, 8i9v:LT, 8i9w:LT, 8i9x:LT, 8i9y:LT, 8i9z:LT, 8ia0:LT, 7old:LT, 8oo0:LT, 8pv1:LT, 8pv2:LT, 8pv3:LT, 8pv4:LT, 8pv5:LT, 8pv6:LT, 8pv7:LT, 8pv8:LT, 8pvk:LT, 8pvl:LT, 7z3n:LT, 7z3o:LT
14 5t5h:U 126 102 0.3333 0.4127 0.5098 1.76e-35
15 9bh5:CT 160 146 0.4038 0.3937 0.4315 3.80e-34 9cai:CT
16 8rxh:LS 158 104 0.3205 0.3165 0.4808 2.98e-33 8a3w:S, 8a98:S, 6az3:S, 3jcs:S, 8ovj:S, 8rxx:LS, 5t2a:S
17 7r81:V1 159 136 0.3718 0.3648 0.4265 6.42e-33
18 4v8p:BP 156 139 0.3974 0.3974 0.4460 7.56e-32 4v8p:CP, 4v8p:EP, 4v8p:GP
19 6zj3:Lh 158 134 0.3462 0.3418 0.4030 1.48e-30
20 8br8:LU 157 155 0.3718 0.3694 0.3742 1.84e-30 8brm:LU, 8bsi:LU, 8bsj:LU, 8btd:LU, 8btr:LU, 8fru:T, 7pwg:T, 7pwo:T2
21 5xy3:T 158 134 0.3526 0.3481 0.4104 1.98e-30
22 7cpu:LT 160 138 0.3718 0.3625 0.4203 3.05e-30 7a01:72, 8a3d:N, 5aj0:AT, 8b5l:T, 8b6c:T, 9bdl:AL21, 9bdn:AL21, 9bdp:AL21, 7bhp:LT, 8bhf:G1, 8bpo:S2, 8btk:BT, 7cpv:LT, 4d5y:T, 4d67:T, 6d90:T, 6d9j:T, 9f1b:BT, 9f1c:BT, 9f1d:BT, 7f5s:LT, 8fkp:LE, 8fkq:LE, 8fkr:LE, 8fks:LE, 8fkt:LE, 8fku:LE, 8fkv:LE, 8fkw:LE, 8fkx:LE, 8fky:LE, 8fkz:LE, 8fl0:LE, 8fl2:LE, 8fl3:LE, 8fl4:LE, 8fl6:LE, 8fl7:LE, 8fl9:LE, 8fla:LE, 8flb:LE, 8flc:LE, 8fld:LE, 8fle:LE, 8flf:LE, 6frk:T, 6ftg:T, 6fti:T, 6ftj:T, 8g5y:LT, 8g5z:LT, 8g60:LT, 8g61:LT, 8g6j:LT, 8glp:LT, 6gz3:AT, 6gz4:AT, 6gz5:AT, 6hcf:T3, 6hcj:T3, 6hcm:T3, 6hcq:T3, 8idt:c, 8idy:c, 8ie3:c, 8ifd:2N, 8ife:2N, 8ine:c, 8inf:c, 8ink:T, 6ip5:2N, 6ip6:2N, 6ip8:2N, 8ipd:T, 8ipx:T, 8ipy:T, 8ir1:c, 8ir3:c, 3j7o:T, 3j7p:T, 3j7q:T, 3j7r:T, 3j92:T, 3jag:T, 3jah:T, 3jai:T, 3jaj:T, 3jan:T, 8jdj:Y, 8jdk:Y, 8jdl:Y, 8jdm:Y, 8k2c:LT, 5lks:LT, 6lqm:c, 6lsr:c, 6lss:c, 7ls1:N2, 7ls2:N2, 6lu8:c, 5lzs:T, 5lzt:T, 5lzu:T, 5lzv:T, 5lzw:T, 5lzx:T, 5lzy:T, 5lzz:T, 7mdz:T, 6mtb:T, 6mtc:T, 6mtd:T, 6mte:T, 7nfx:T, 7nwg:T3, 7nwh:T, 7nwi:T, 7o7y:BT, 7o7z:BT, 7o80:BT, 7o81:BT, 7obr:T, 8ohd:LT, 8oj0:LT, 8oj5:LT, 8oj8:LT, 6ole:U, 6olf:U, 6olg:AT, 6oli:U, 6olz:AT, 6om0:U, 6om7:U, 7ow7:N, 7oyd:T, 8p2k:BT, 6p5i:AT, 6p5j:AT, 6p5k:AT, 6p5n:AT, 8q7z:BT, 8q87:BT, 8qfd:T, 7qgg:U, 8qoi:LT, 7qvp:LT, 7qvp:MT, 7qwq:T, 7qwr:T, 7qws:T, 6qzp:LT, 6r5q:T, 6r6g:T, 6r6p:T, 6r7q:T, 8rjb:T, 8rjc:T, 8rjd:T, 8scb:T, 6sgc:T2, 6swa:R, 5t2c:N, 6t59:T3, 7tm3:T, 7toq:AL21, 7tor:AL21, 7tut:T, 7ucj:T, 7uck:T, 4ug0:LT, 4ujc:BT, 4ujd:AT, 4uje:CT, 4v5z:Bq, 4v6x:CT, 6w6l:U, 6xa1:LT, 7xnx:LT, 7xny:LT, 8xsx:LT, 8xsy:LT, 8xsz:LT, 6y0g:LT, 8y0w:LT, 8y0x:LT, 6y2l:LT, 6y57:LT, 6y6x:LT, 8yoo:LT, 8yop:LT, 6z6l:LT, 6z6m:LT, 6z6n:LT, 7zjw:LW, 7zjx:LW, 6zm7:LT, 6zme:LT, 6zmi:LT, 6zmo:LT, 6zvk:72
23 3j79:V 155 137 0.3782 0.3806 0.4307 3.27e-30 3jbn:AV, 3jbo:AV, 3jbp:AV, 8tpu:AV, 5umd:V
24 7oya:T1 157 138 0.3782 0.3758 0.4275 8.81e-28 7oyb:T1
25 7oyc:T1 157 138 0.3782 0.3758 0.4275 3.88e-27
26 8hku:L21E 97 62 0.1923 0.3093 0.4839 5.64e-16 8hkv:L21E, 8hky:L21E, 8hkz:L21E, 8hl1:L21E, 8hl2:L21E, 8hl3:L21E, 8hl4:L21E, 8hl5:L21E
27 6skf:BU 96 61 0.1603 0.2604 0.4098 1.29e-12 6skg:BU, 6th6:BU, 4v4n:AR, 4v6u:BR
28 3cc2:Q 95 96 0.1474 0.2421 0.2396 0.001 3cc4:Q, 3cc7:Q, 3cce:Q, 3ccj:Q, 3ccl:Q, 3ccm:Q, 3ccq:Q, 3ccr:Q, 3ccs:Q, 3ccu:Q, 3ccv:Q, 3cd6:Q, 3cma:Q, 3cme:Q, 3cpw:P, 3cxc:P, 1ffk:N, 3g4s:Q, 3g6e:Q, 3g71:Q, 3i55:Q, 3i56:Q, 1jj2:P, 1k73:R, 1k8a:R, 1k9m:R, 1kc8:R, 1kd1:R, 1kqs:P, 1m1k:R, 1m90:R, 1n8r:R, 1nji:R, 2otj:Q, 2otl:Q, 3ow2:P, 1q7y:R, 1q81:R, 1q82:R, 1q86:R, 2qa4:Q, 2qex:Q, 1qvf:P, 1qvg:P, 1s72:Q, 4v9f:Q, 1vq4:Q, 1vq5:Q, 1vq6:Q, 1vq7:Q, 1vq8:Q, 1vq9:Q, 1vqk:Q, 1vql:Q, 1vqm:Q, 1vqn:Q, 1vqo:Q, 1vqp:Q, 1w2b:P, 1yhq:Q, 1yi2:Q, 1yij:Q, 1yit:Q, 1yj9:Q, 1yjn:Q, 1yjw:Q
29 7u0h:T 57 29 0.0769 0.2105 0.4138 0.33
30 1f8v:A 355 37 0.1026 0.0451 0.4324 0.83 1f8v:B, 1f8v:C
31 4pu6:B 131 43 0.0962 0.1145 0.3488 2.1
32 4e1o:C 481 48 0.0897 0.0291 0.2917 4.0 4e1o:A, 4e1o:B, 4e1o:D, 4e1o:E, 4e1o:F, 7eiw:A, 7eiw:B, 7eix:A, 7eix:B, 7eiy:A, 7eiy:B
33 8fru:O 196 29 0.0769 0.0612 0.4138 4.3 8br8:LP, 8brm:LP, 8bsi:LP, 8bsj:LP, 8btd:LP, 8btr:LP, 7pwg:O, 7pwo:O2
34 4bxx:B 1097 47 0.0833 0.0119 0.2766 7.6 4bxz:B, 3cqz:B, 1i3q:B, 1i50:B, 1i6h:B, 1k83:B, 1nik:B, 2nvy:B, 1r5u:B, 1r9s:B, 1twa:B, 1twc:B, 1twf:B, 1twg:B, 1twh:B, 5w4u:B, 5w51:B, 1wcm:B
35 3k7a:B 1122 47 0.0833 0.0116 0.2766 7.9
36 6ud7:A 426 66 0.1154 0.0423 0.2727 8.0 6pai:C, 6q0r:B, 6q0r:C, 6q0v:B, 6q0w:B, 6ue5:A
37 2d7d:A 621 50 0.0962 0.0242 0.3000 10.0 2nmv:A, 3v4r:B, 3v4r:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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