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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGENAANI
ASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQALRNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQ
VHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLSTEGQVQELVFPQEYASESSIQLSANTIKQNSRNGVVK
VVFILYNNLGLFLSTENATVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEAKNHFNANCSFW
NYSERSMLGYWSTQGCRLVESNKTHTTCACSHL

The query sequence (length=353) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4dlq:A 353 353 1.0000 1.0000 1.0000 0.0
2 6v55:A 746 356 0.2465 0.1166 0.2444 1.05e-13
3 8hc0:A 360 76 0.0652 0.0639 0.3026 0.013
4 2jnd:A 79 43 0.0510 0.2278 0.4186 0.064
5 6wzg:R 379 163 0.1076 0.1003 0.2331 0.17 7d3s:R, 6wi9:R
6 3n96:A 473 21 0.0312 0.0233 0.5238 0.99 3ehs:A, 3eht:A, 3n93:B, 3n93:A, 3n95:C, 3n95:D, 3n95:A, 3n95:B, 3n96:C, 3n96:D, 3n96:B
7 2e52:A 299 56 0.0510 0.0602 0.3214 1.1 3a4k:A, 3a4k:B, 3a4k:C, 3a4k:D, 2e52:B, 2e52:C, 2e52:D, 3wvg:C, 3wvg:D, 3wvg:A, 3wvg:B, 3wvh:B, 3wvh:A, 3wvh:D, 3wvh:C, 3wvi:A, 3wvi:B, 3wvi:C, 3wvi:D, 3wvk:D, 3wvk:A, 3wvk:B, 3wvk:C, 3wvp:C, 3wvp:D, 3wvp:A, 3wvp:B
8 5kvm:A 355 59 0.0652 0.0648 0.3898 1.9
9 6evm:A 95 52 0.0368 0.1368 0.2500 2.5 6evl:A, 6evn:A, 6evo:A, 6evp:A
10 5trd:A 219 65 0.0567 0.0913 0.3077 2.5 5trd:B
11 5e7p:A 719 88 0.0737 0.0362 0.2955 3.6 5e7p:B
12 8tl6:A 798 36 0.0425 0.0188 0.4167 3.8 8g46:A
13 5dj4:A 366 64 0.0538 0.0519 0.2969 7.0 5dj4:B, 5dj4:C, 5dj4:D, 5dj4:E, 6n0m:A, 6n0m:B, 6n0m:C, 6n0m:D, 6n0m:E, 5t0n:A, 5t0n:B, 5t0n:C, 5t0n:D, 5t0n:E
14 6k31:A 1109 109 0.0708 0.0225 0.2294 9.5 6k31:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218