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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VRKLKFHEQKLLKQVDFLNWEREDYTRYNQLSRAVRELARRLRDLPERDQFRVRASAALLDKLYALGLVPTRGSLELCDF
VTASSFCRRRLPTVLLKLRMAQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHVLEYNEERDDF
DL

The query sequence (length=162) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7mqa:LZ 162 162 1.0000 1.0000 1.0000 2.32e-117
2 7mq8:LZ 183 181 1.0000 0.8852 0.8950 1.32e-112 7mq9:LZ
3 7ajt:CI 182 181 0.5679 0.5055 0.5083 1.76e-60 7aju:CI, 7d4i:5F, 7d5s:5F, 7d5t:5F, 7d63:5F, 6ke6:5F, 6lqp:5F, 6lqq:5F, 6lqr:5F, 6lqs:5F, 6lqt:5F, 6lqu:5F, 6lqv:5F, 6nd4:Z, 7suk:LZ, 5wlc:LZ, 5wxm:A, 5wyj:MA, 5wyk:MA, 6zqa:CI, 6zqb:CI, 6zqc:CI, 6zqd:CI
4 5oql:a 179 179 0.5309 0.4804 0.4804 2.27e-53 6rxt:CJ, 6rxu:CJ, 6rxv:CJ, 6rxx:CJ, 6rxy:CJ, 6rxz:CJ
5 5xxu:J 178 141 0.2963 0.2697 0.3404 5.41e-12
6 5xyi:J 162 111 0.2284 0.2284 0.3333 1.96e-11
7 6skf:Ae 174 86 0.1728 0.1609 0.3256 1.39e-10 6skg:Ae, 6th6:Ae
8 7olc:SJ 179 97 0.2037 0.1844 0.3402 2.25e-09 7old:SJ, 8oo0:SJ, 5oql:r, 7r81:K2, 6rxt:Cg, 6rxu:Cg, 6rxv:Cg, 6rxx:Cg, 6rxy:Cg, 6rxz:Cg, 7z3n:SJ, 7z3o:SJ
9 6zj3:SD 177 113 0.2222 0.2034 0.3186 3.01e-09
10 7qix:Q 184 101 0.2222 0.1957 0.3564 3.29e-09 8auv:b, 8b2l:b1, 7qiz:GA
11 4v8m:A6 186 138 0.2469 0.2151 0.2899 3.74e-09 8a3w:SD, 8a98:SD, 7ase:B, 6az1:D, 5opt:b, 8ova:A6, 8ove:A6, 8ovj:SD, 8rxh:SD, 8rxx:SD, 5t2a:6
12 4v3p:SC 195 115 0.2284 0.1897 0.3217 5.24e-09 8ip8:eb, 8ip9:eb, 8ipa:eb, 8ipb:eb, 8jiw:BJ, 8r6f:J, 4v7e:BJ
13 6sw9:D 175 86 0.1605 0.1486 0.3023 1.12e-08 5jb3:D, 5jbh:D, 6swc:D, 6swd:D, 4v4n:BD, 4v6u:AD, 7zag:D, 7zah:D, 7zai:D, 7zhg:D
14 3j7a:E 185 164 0.2840 0.2486 0.2805 2.08e-08 3jbn:E, 3jbo:E, 3jbp:E, 6okk:E, 8tpu:SE
15 4v6w:AJ 181 97 0.2037 0.1823 0.3402 2.36e-08 6xu6:AJ, 6xu7:AJ, 6xu8:AJ
16 8hkx:AS4P 166 118 0.2099 0.2048 0.2881 2.46e-08 8hky:AS4P, 8hkz:AS4P, 8hl1:AS4P, 8hl2:AS4P, 8hl3:AS4P, 8hl4:AS4P, 8hl5:AS4P, 8wkp:AS4P, 8wq2:AS4P, 8wq4:AS4P
17 6tmf:E 178 90 0.1667 0.1517 0.3000 3.11e-08
18 4bts:AD 180 112 0.1914 0.1722 0.2768 4.83e-08 4bts:BD, 4bts:CD, 4bts:DD, 4v5o:AD, 4v5o:BD
19 9bh5:AJ 177 97 0.2037 0.1864 0.3402 9.34e-08 9cai:AJ
20 8p03:L 188 99 0.2099 0.1809 0.3434 1.20e-07 7a01:d3, 7a09:c, 5a2q:J, 5aj0:BJ, 9bdl:AS09, 9bdn:AS09, 9bdp:AS09, 8bhf:K3, 9bkd:D, 9bln:D, 8btk:Ai, 7cpu:SJ, 7cpv:SJ, 4d5l:J, 4d61:J, 6d90:KK, 6d9j:KK, 9f1b:Ai, 9f1c:Ai, 9f1d:Ai, 6fec:K, 5flx:J, 6g18:J, 6g4s:J, 6g4w:J, 6g51:J, 6g53:J, 6g5h:J, 6g5i:J, 8g5y:SJ, 8g5z:SJ, 8g60:SJ, 8g61:SJ, 8g6j:SJ, 8glp:SJ, 6gz3:BJ, 6gz4:BJ, 6gz5:BJ, 6hcf:K1, 6hcj:K2, 6hcm:K1, 6hcq:K2, 8ifd:3I, 8ife:3I, 6ip5:3I, 6ip6:3I, 6ip8:3I, 3j7p:SJ, 3j7r:SJ, 3jag:JJ, 3jah:JJ, 3jai:JJ, 3jaj:SJ, 3jan:SJ, 8jdj:6, 8jdk:6, 8jdl:6, 8jdm:6, 7jqb:K, 7jqc:K, 5k0y:K, 8k2c:SJ, 7k5i:J, 4kzx:J, 4kzy:J, 4kzz:J, 5lks:SJ, 7ls1:L3, 7ls2:L3, 5lzs:JJ, 5lzt:JJ, 5lzu:JJ, 5lzv:JJ, 5lzw:JJ, 5lzx:JJ, 5lzy:JJ, 5lzz:JJ, 7mdz:JJ, 7mq8:L9, 7mq9:L9, 7mqa:L9, 6mtb:JJ, 6mtc:JJ, 6mtd:JJ, 6mte:JJ, 7nwg:K2, 7nwh:JJ, 7nwi:JJ, 7o7y:Ai, 7o7z:Ai, 7o80:Ai, 7o81:Ai, 5oa3:J, 6ole:SJ, 6olf:SJ, 6olg:BJ, 6oli:SJ, 6olz:BJ, 6om0:SJ, 6om7:SJ, 7oya:J2, 7oyb:J2, 7oyc:J2, 7oyd:JJ, 8oz0:Z, 8p09:L, 8p2k:Ai, 6p4g:K, 6p4h:K, 6p5i:K, 6p5j:K, 6p5k:K, 6p5n:K, 8pj1:D, 8pj2:D, 8pj3:D, 8pj4:D, 8pj5:D, 8pj6:D, 8ppk:J, 8ppl:AJ, 8q7z:Ai, 8q87:Ai, 7qgg:SJ, 8qoi:SJ, 7qp6:D, 7qp7:D, 7qvp:SJ, 7qvp:RJ, 6qzp:SJ, 7r4x:J, 6r5q:DD, 6r6g:DD, 6r6p:XX, 6r7q:DD, 8scb:JJ, 6sgc:K1, 7syg:K, 7syh:K, 7syi:K, 7syj:K, 7syk:K, 7syl:K, 7sym:K, 7syn:K, 7syo:K, 7syp:K, 7syq:K, 7syr:K, 7sys:K, 7syt:K, 7syu:K, 7syv:K, 7syw:K, 7syx:K, 5t2c:AL, 8t4s:J, 7toq:AS09, 7tor:AS09, 7tql:J, 7ucj:JJ, 7uck:JJ, 4ug0:SJ, 4ujc:CJ, 4ujd:CJ, 4uje:BJ, 4v6x:AJ, 5vyc:J1, 5vyc:J2, 5vyc:J3, 5vyc:J4, 5vyc:J5, 5vyc:J6, 6w2s:K, 6w2t:K, 7wts:J, 7wtt:J, 7wtu:J, 7wtv:J, 7wtw:J, 7wtx:J, 7wtz:J, 7wu0:J, 6xa1:SJ, 7xnx:SJ, 7xny:SJ, 8xsx:SJ, 8xsy:SJ, 8xsz:SJ, 8xxl:SJ, 8xxm:SJ, 8xxn:SJ, 6y0g:SJ, 8y0w:SJ, 8y0x:SJ, 6y2l:SJ, 6y57:SJ, 6yal:L, 6yam:L, 6yan:L, 6ybw:D, 8yoo:SJ, 8yop:SJ, 6z6l:SJ, 6z6m:SJ, 6z6n:SJ, 7zjw:SU, 7zjx:SU, 6zlw:J, 6zm7:SJ, 6zme:SJ, 6zmi:SJ, 6zmo:SJ, 6zmt:J, 6zmw:D, 6zn5:J, 6zoj:J, 6zok:J, 6zon:c, 6zp4:c, 6zuo:J, 6zv6:J, 6zvh:J, 6zvj:c, 6zvk:d3, 6zxd:J, 6zxe:J, 6zxf:J, 6zxg:J, 6zxh:J
21 8br8:SK 176 130 0.2284 0.2102 0.2846 2.55e-07 8brm:SK, 8bsi:SK, 8bsj:SK, 8btd:SK, 8btr:SK, 8fvy:J, 8g4s:J, 7pwf:J, 7pwo:J1
22 8c3a:L 178 130 0.2469 0.2247 0.3077 7.76e-07 8c3a:CW, 8cq7:L, 8cq7:CW, 8cqw:L, 8cqw:CW, 8cre:L, 8cre:CW, 8oeq:L, 8oeq:CW, 7pzy:K, 7q08:K, 7q0f:K, 7q0p:K, 7q0r:K, 8q5i:K
23 4v7h:AD 124 121 0.1975 0.2581 0.2645 3.05e-06
24 4v6i:AC 196 128 0.2284 0.1888 0.2891 2.35e-05 7a1g:W, 7ajt:DJ, 7aju:DJ, 7b7d:W, 8bn3:S9, 8bqd:W, 8bqx:W, 8c00:W, 8c01:W, 8c83:W, 8cah:W, 8cas:W, 8cbj:J, 8ccs:m, 8cdl:m, 8cdr:m, 8ceh:m, 8cf5:m, 8cg8:m, 8cgn:m, 8civ:m, 8cku:m, 8cmj:m, 7d4i:SK, 7d5s:SK, 7d5t:SK, 7d63:SK, 5dat:S9, 5dat:s9, 5dc3:S9, 5dc3:s9, 5dge:S9, 5dge:s9, 5dgf:S9, 5dgf:s9, 5dgv:S9, 5dgv:s9, 6eml:W, 8eub:BJ, 8evp:BJ, 8evq:BJ, 8evr:BJ, 8evs:BJ, 8evt:BJ, 8ewb:BJ, 8ewc:BJ, 6fai:J, 5fci:S9, 5fci:s9, 5fcj:S9, 5fcj:s9, 6fyx:J, 6fyy:J, 6gq1:z, 6gqb:z, 6gqv:z, 6gsm:J, 6gsn:J, 6hhq:K, 6hhq:s9, 5i4l:S9, 5i4l:s9, 6i7o:W, 6i7o:Wb, 8i7j:J, 5it7:J, 5it9:J, 3j6x:S9, 3j6y:S9, 3j77:S9, 3j78:S9, 3j80:J, 3j81:J, 3jam:J, 3jap:J, 5juo:GB, 5jup:GB, 5jus:GB, 5jut:GB, 5juu:GB, 8k2d:SJ, 8k82:SJ, 6ke6:SK, 5ll6:W, 6lqp:SK, 6lqq:SK, 6lqr:SK, 6lqs:SK, 6lqt:SK, 6lqu:SK, 6lqv:SK, 5lyb:S9, 5lyb:s9, 5m1j:J2, 5mc6:W, 5mei:s9, 5mei:K, 7mpi:BJ, 7mpj:BJ, 7n8b:BJ, 5ndg:S9, 5ndg:s9, 5ndv:S9, 5ndv:s9, 5ndw:S9, 5ndw:s9, 7nrc:SW, 7nrd:SW, 5obm:S9, 5obm:s9, 5on6:s9, 5on6:K, 7osa:uS4, 7osm:uS4, 6q8y:W, 6rbd:J, 6rbe:J, 7rr5:SJ, 8rw1:J, 6s47:BK, 8s8d:J, 8s8e:J, 8s8f:J, 8s8g:J, 8s8h:J, 8s8i:J, 8s8j:J, 6snt:J, 7suk:L9, 6sv4:W, 6sv4:Wb, 6sv4:Wc, 6t4q:SJ, 6t7i:SJ, 6t7t:SJ, 6t83:Jb, 6t83:k, 5tbw:K, 5tbw:s9, 6tb3:W, 5tga:S9, 5tga:s9, 5tgm:S9, 5tgm:s9, 6tnu:W, 5tzs:9, 4u3m:S9, 4u3m:s9, 4u3n:S9, 4u3n:s9, 4u3u:S9, 4u3u:s9, 4u4n:S9, 4u4n:s9, 4u4o:S9, 4u4o:s9, 4u4q:S9, 4u4q:s9, 4u4r:S9, 4u4r:s9, 4u4u:S9, 4u4u:s9, 4u4y:S9, 4u4y:s9, 4u4z:S9, 4u4z:s9, 4u50:S9, 4u50:s9, 4u51:S9, 4u51:s9, 4u52:S9, 4u52:s9, 4u53:S9, 4u53:s9, 4u55:S9, 4u55:s9, 4u56:S9, 4u56:s9, 4u6f:S9, 4u6f:s9, 4uer:D, 6uz7:J, 4v4b:AD, 4v7r:AE, 4v7r:CE, 4v88:AJ, 4v88:CJ, 4v8y:AJ, 4v8z:AJ, 4v92:BJ, 6wdr:J, 5wlc:L9, 6woo:JJ, 7wtl:SJ, 7wtm:SJ, 7wtn:SJ, 7wto:SJ, 7wtp:SJ, 7wtq:SJ, 7wtr:SJ, 5wyj:SK, 5wyk:SK, 6xiq:z, 6xir:z, 8y0u:SJ, 6y7c:J, 6z6j:SJ, 6z6k:SJ, 6zce:K, 7zpq:AJ, 6zqa:DJ, 6zqb:DJ, 6zqc:DJ, 6zqd:DJ, 6zqe:DJ, 6zqf:DJ, 6zqg:DJ, 7zrs:AJ, 6zu9:W, 7zuw:AJ, 7zux:DJ, 6zvi:r, 7zw0:sW
25 8p5d:SJ0 168 65 0.1173 0.1131 0.2923 6.22e-04 8p60:SJ0, 8p60:RJ0, 7qca:SJ0
26 6zu5:SJ0 164 142 0.2346 0.2317 0.2676 0.002
27 6sqx:B 457 73 0.1296 0.0460 0.2877 1.1
28 5ljf:A 321 88 0.1296 0.0654 0.2386 1.8 5ljf:B, 4m24:A, 7p6h:A, 7p6h:B, 7p6j:A, 7p6j:B, 7p6j:C, 7p6j:D, 6zz3:A, 6zz3:B, 6zz3:C, 6zz3:D
29 6fh4:C 78 43 0.0988 0.2051 0.3721 2.0 6fh4:A, 6fh4:B
30 3kv6:D 448 52 0.0926 0.0335 0.2885 2.6 3kv5:D, 3kv5:A, 3kv6:A, 3kv9:A, 3kva:A, 3u78:A
31 3jce:x 586 66 0.1173 0.0324 0.2879 9.7 3deg:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218