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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQA
AYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTFV
PCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVNIGMDQAHLVGLGRYLILNGVVDR
SLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSADGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFR
NHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDL
DGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPHFAQAAETLANIKEKA
GNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIR
MGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIYTT

The query sequence (length=625) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5a6k:A 626 625 0.9984 0.9968 0.9984 0.0 5a6a:A, 5a6b:A, 5a6b:B, 5a6b:C, 5a6b:D, 5a6k:B, 5ac4:A, 5ac4:B, 5ac5:A, 5ac5:B
2 5a6a:B 597 625 0.9536 0.9983 0.9536 0.0 5a69:A
3 2epn:A 623 624 0.7232 0.7255 0.7244 0.0 2epn:B
4 6k35:A 640 228 0.0832 0.0813 0.2281 0.002 6k35:B
5 4pys:A 492 112 0.0480 0.0610 0.2679 0.22 4pys:B
6 4xwh:A 720 29 0.0208 0.0181 0.4483 0.26
7 1yht:A 344 190 0.0592 0.1076 0.1947 0.54
8 8pxv:B 634 167 0.0496 0.0489 0.1856 0.65 8pxv:C
9 4azc:B 421 160 0.0560 0.0831 0.2188 1.9 4azc:A, 4azc:C, 4azc:D, 4azg:A, 4azg:B, 4azh:A, 4azh:B, 4azh:C, 4azh:D, 4azi:A, 4azi:B, 2yl5:A, 2yl5:C, 2yl9:C, 2yla:B, 2yla:C
10 5ti1:H 430 145 0.0608 0.0884 0.2621 6.6 5ti1:A, 5ti1:B, 5ti1:C, 5ti1:D, 5ti1:E, 5ti1:F, 5ti1:G
11 6n7p:D 544 120 0.0416 0.0478 0.2167 6.7 6g90:E, 6n7r:D, 6n7x:D, 7oqc:E, 7oqe:E, 8w2o:D, 5zwn:T
12 6je8:A 469 115 0.0416 0.0554 0.2261 6.8 6jea:A, 6jeb:A
13 6aqp:C 399 134 0.0560 0.0877 0.2612 8.9 6aqp:A, 6aqp:B, 6aqp:D, 6are:A, 6are:B, 6are:C, 6are:D
14 7yw2:A 206 29 0.0224 0.0680 0.4828 9.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218