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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VREWSGINTFAPATQTKLLELLGNLKQEDVNSLTILVMGKGGVGKSSTVNSIIGERVVSISPFQSEGPRPVMVSRSRAGF
TLNIIDTPGLIEGGYINDMALNIIKSFLLDKTIDVLLYVDRLDAYRVDNLDKLVAKAITDSFGKGIWNKAIVALTHAQFS
PPDGLPYDEFFSKRSEALLQVVRSGASLKKDAQASDIPVVLIENSGRCNKNDSDEKVLPNGIAWIPHLVQTITEVALNKS
ESIFVDKNLIDKLAAA

The query sequence (length=256) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h65:A 257 256 1.0000 0.9961 1.0000 0.0 3bb1:A, 3bb1:B, 3bb1:C, 3bb1:D, 3bb1:E, 3bb1:F, 3bb1:G, 3bb1:H, 1h65:B, 1h65:C
2 2j3e:A 249 246 0.6133 0.6305 0.6382 7.67e-116 3bb3:A, 3bb4:A, 3def:A
3 3zjc:E 286 196 0.1953 0.1748 0.2551 1.23e-05 3zjc:A, 3zjc:B, 3zjc:C, 3zjc:D
4 6z3e:A 237 130 0.1445 0.1561 0.2846 1.87e-05
5 3zjc:F 252 61 0.0977 0.0992 0.4098 6.86e-05
6 6xrs:B 392 50 0.0820 0.0536 0.4200 0.005 6xrs:A, 6xrs:D, 6xrs:C
7 2xto:A 224 136 0.1445 0.1652 0.2721 0.006 2xtm:A, 2xtm:B, 2xtn:A, 2xto:B
8 8fl2:NC 511 84 0.0898 0.0450 0.2738 0.014 8fkz:NC, 8fl0:NC, 8fl3:NC, 8fl4:NC, 8idt:A, 8idy:A, 8ie3:A, 8ine:A, 8inf:A, 8ink:w, 8ipd:w, 8ipx:w, 8ipy:w, 8ir1:w, 8ir3:w
9 3lxx:A 169 149 0.1680 0.2544 0.2886 0.014
10 2qag:C 224 58 0.0742 0.0848 0.3276 0.022
11 5t62:W 306 72 0.0859 0.0719 0.3056 0.032
12 6n8n:W 377 61 0.0820 0.0557 0.3443 0.045 6n8o:W
13 1wf3:A 296 69 0.0859 0.0743 0.3188 0.055
14 8eti:b 391 95 0.1133 0.0742 0.3053 0.062 8esr:b, 8etg:b
15 8etc:b 415 95 0.1133 0.0699 0.3053 0.065 8esq:b, 8etj:b
16 6qtz:o 325 61 0.0820 0.0646 0.3443 0.067 6qik:o, 6ri5:o, 6rzz:o, 6s05:o
17 3j8g:X 418 108 0.1055 0.0646 0.2500 0.100
18 2e87:A 356 78 0.0938 0.0674 0.3077 0.10
19 6yxx:EA 532 67 0.0938 0.0451 0.3582 0.12 7aoi:XL, 6yxy:EA
20 6yxx:EA 532 111 0.1094 0.0526 0.2523 2.9 7aoi:XL, 6yxy:EA
21 8sgd:A 291 78 0.0742 0.0653 0.2436 0.15 8fwp:A, 8pfh:A, 8sgd:C
22 5cyo:A 272 76 0.0820 0.0772 0.2763 0.15 5cyo:B, 4yqf:B, 4yqf:A
23 3ftq:B 252 58 0.0625 0.0635 0.2759 0.18 3ftq:C, 3ftq:D, 2qnr:B, 6upa:A
24 5cyp:A 248 74 0.0859 0.0887 0.2973 0.18 5cyp:B, 5cyp:C
25 4zi2:A 185 72 0.0820 0.1135 0.2917 0.20 3bh6:A, 3bh7:A, 1fzq:A, 4goj:A, 4goj:B, 7ok7:A, 7ok7:B, 7ok7:C, 7ok7:D, 7ok7:E, 7ok7:F, 4zi2:B, 4zi3:A, 4zi3:B
26 3doe:A 189 72 0.0859 0.1164 0.3056 0.20 3dof:A, 4gok:B, 4gok:A, 1ksg:A, 1ksh:A, 1ksj:A
27 2kwi:A 178 76 0.0898 0.1292 0.3026 0.20 2ke5:A, 6zqt:A, 6zqt:B, 6zrn:A, 6zrn:B
28 7btb:m 469 84 0.0781 0.0426 0.2381 0.27 7bt6:m, 6ft6:m, 3jct:m, 6m62:m, 7oh3:m, 7ohq:m, 7oht:m, 7ug6:m, 7uoo:m, 7uqb:m, 7uqz:m, 7uui:m, 7v08:m, 6ylg:m, 6ylh:m
29 6lsr:1 247 85 0.0977 0.1012 0.2941 0.29
30 5de3:A 166 55 0.0742 0.1145 0.3455 0.35 5di3:A
31 8fl4:SR 593 85 0.0859 0.0371 0.2588 0.35 8fkr:SR, 8fks:SR
32 7am2:BU 463 66 0.0664 0.0367 0.2576 0.37
33 5m7h:A 420 56 0.0664 0.0405 0.3036 0.42 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
34 5m7h:A 420 84 0.0898 0.0548 0.2738 4.4 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
35 8ir1:4 620 85 0.0859 0.0355 0.2588 0.44 8fkt:SR, 8fku:SR, 8fkv:SR, 8fkw:SR, 8fkx:SR, 8fky:SR, 8fkz:SR, 8fl0:SR, 8fl2:SR, 8fl3:SR, 8fl6:SR, 8fl7:SR, 8fl9:SR, 8fla:SR, 8flb:SR, 8flc:SR, 8fld:SR, 8fle:SR, 8flf:SR, 8idt:4, 8idy:4, 8ie3:4, 8ine:4, 8inf:4, 8ink:4, 8ipd:4, 8ipx:4, 8ipy:4, 8ir3:4, 6lss:4, 6lu8:4
36 8pv1:Cd 462 82 0.0820 0.0455 0.2561 0.48 8pv2:Cd, 8pv3:Cd, 8pv4:Cd, 8pv5:Cd, 8pv6:Cd, 8pv7:Cd, 8pv8:Cd, 8pvk:Cd, 8pvl:Cd
37 6uqq:C 280 76 0.0938 0.0857 0.3158 0.62 3sop:A, 3sop:B, 6uqq:D, 4z51:A, 4z54:A, 4z54:B
38 5xc3:A 168 57 0.0742 0.1131 0.3333 0.63 5xc5:A
39 6mq9:B 267 76 0.0820 0.0787 0.2763 0.71 6mq9:A, 6mq9:D, 6mq9:C, 6mqb:A, 6mqk:A, 6mqk:D, 6mqk:B, 6mqk:C, 6mql:A
40 5cyp:D 227 67 0.0742 0.0837 0.2836 0.87
41 8hpl:C 384 98 0.1094 0.0729 0.2857 0.94 7cag:C, 7cag:D, 8hpl:D, 8hpm:C, 8hpm:D, 8hpn:C, 8hpn:D, 8hpr:C, 8hpr:D, 8hps:C, 8hps:D
42 8v83:b 423 71 0.0781 0.0473 0.2817 0.96 6elz:b, 6em1:b, 6em5:b, 7ohp:b, 7ohr:b, 7ohs:b, 7ohu:b, 7ohv:b, 8v84:b
43 7m6j:D 273 71 0.0781 0.0733 0.2817 0.98 7m6j:C, 6n0b:C, 6n0b:A, 6n0b:B, 6n0b:D, 6n12:A, 6n12:B, 3t5d:A, 3t5d:C, 6uqq:A, 6uqq:B
44 7ohy:b 375 70 0.0781 0.0533 0.2857 1.1
45 6upq:A 270 70 0.0820 0.0778 0.3000 1.3 3ftq:A, 7m6j:F, 6upr:A
46 3a1s:A 255 92 0.0938 0.0941 0.2609 1.5 3a1s:B, 3a1t:A, 3a1u:A, 3a1u:B
47 3iev:A 302 66 0.0820 0.0695 0.3182 1.5 7c1o:A, 3r9w:A, 3r9x:A
48 6n8j:m 378 84 0.0742 0.0503 0.2262 1.5
49 7m6j:A 234 69 0.0820 0.0897 0.3043 1.6
50 3v70:A 217 22 0.0430 0.0507 0.5000 1.9 3v70:B
51 6ylg:b 613 76 0.0781 0.0326 0.2632 1.9 7nac:b, 7of1:b, 7r7a:b, 6ylh:b
52 3tw4:A 218 59 0.0664 0.0780 0.2881 2.0 3tw4:B
53 7oyd:v 726 52 0.0625 0.0220 0.3077 2.1
54 5dn8:A 405 97 0.1094 0.0691 0.2887 2.2
55 2erx:A 168 84 0.1016 0.1548 0.3095 2.3 2erx:B, 6naz:A
56 8hfr:rA 647 76 0.0781 0.0309 0.2632 2.3 7bt6:b, 7btb:b, 6c0f:W, 6ft6:b, 3jct:b, 5jcs:o, 6m62:b, 6n8j:b, 6n8k:b, 7nad:b, 7oh3:b, 7ohq:b, 7oht:b, 7r72:b, 7u0h:b, 7ug6:b, 7uoo:b, 7uqb:b, 7uqz:b, 7v08:b, 4v7f:o, 8v87:b, 6ylx:b, 6yly:b, 7z34:b
57 2bov:A 173 76 0.0820 0.1214 0.2763 2.4 2a78:A, 2a9k:A, 8fjh:B, 8fji:B, 6p0i:B, 6p0j:B, 6p0k:B, 6p0l:B, 6p0m:B, 6p0n:B, 6p0o:B, 1u8y:A, 1u8y:B, 1u8z:A, 1u8z:B, 1u90:A, 1u90:B, 1uad:A, 1uad:B, 1zc3:A, 1zc3:C, 1zc4:A, 1zc4:C
58 8dkt:A 264 69 0.0703 0.0682 0.2609 2.6
59 3jck:G 257 96 0.0742 0.0739 0.1979 2.9 3j47:V, 4o8x:B, 4ocl:B, 4ocl:E, 4ocm:B, 4ocm:E, 4owp:B, 5u4p:B, 5w83:B
60 3fwy:A 268 30 0.0586 0.0560 0.5000 2.9 3fwy:B, 6uyk:A, 6uyk:B, 6uyk:C, 6uyk:D
61 8osg:B 323 122 0.1328 0.1053 0.2787 2.9 8osf:A, 8osf:B, 8osf:C, 8osf:D, 8osf:E, 8osg:C, 8osg:D, 8osg:E
62 8fkt:NB 387 43 0.0547 0.0362 0.3256 3.1 8fkp:NB, 8fku:NB, 8fkv:NB, 8fkw:NB, 8fkx:NB, 8fky:NB, 8fkz:NB, 8fl0:NB, 8ink:u, 8ipd:u, 8ipx:u, 8ipy:u
63 2vxa:A 66 41 0.0586 0.2273 0.3659 3.4 2vxa:E, 2vxa:K, 2vxa:C, 2vxa:G, 2vxa:D, 2vxa:I, 2vxa:L, 2vxa:F, 2vxa:B, 2vxa:H, 2vxa:J
64 9bht:C 282 63 0.0703 0.0638 0.2857 3.4 9bht:D, 9bhw:A, 9bhw:D
65 7dco:Q 292 40 0.0664 0.0582 0.4250 3.6 6j6g:Q, 6j6h:Q, 6j6n:Q, 6j6q:Q
66 9bhw:B 299 67 0.0703 0.0602 0.2687 3.7 9bhw:C
67 8iue:P 303 63 0.0742 0.0627 0.3016 4.8 7a6h:P, 7ae1:P, 7ae3:P, 7aea:P, 7d58:P, 7d59:P, 7dn3:P, 7du2:P, 7fji:P, 7fjj:P, 8ity:P, 8iuh:P
68 3cnl:A 233 93 0.0938 0.1030 0.2581 5.1 3cnn:A, 3cno:A
69 6kyk:C 169 76 0.0898 0.1361 0.3026 5.2 3brw:D, 1c1y:A, 7c7i:A, 7c7i:B, 7c7j:A, 7c7j:B, 4dxa:A, 1gua:A, 4hdo:B, 4hdq:B, 5kho:C, 5kho:D, 3kuc:A, 4kvg:A, 4kvg:C, 6kyk:D, 6kyk:E, 6kyk:F, 4m8n:E, 4m8n:F, 4m8n:G, 4m8n:H, 6oq3:B, 6oq4:B, 8su8:B, 8t09:B, 8t7v:B, 6uzk:B, 3x1w:A, 3x1x:A, 3x1y:A, 3x1z:A, 3x1z:B
70 2ocb:A 173 59 0.0781 0.1156 0.3390 5.5
71 6mfz:A 1789 35 0.0508 0.0073 0.3714 6.3 5es7:A, 5es8:A, 5es8:B, 5es9:A, 6mfw:A, 6mfx:A, 6mfy:A, 6mg0:A, 6ulz:A
72 6mg0:B 1687 35 0.0508 0.0077 0.3714 6.3
73 2ynm:B 268 35 0.0547 0.0522 0.4000 6.4 2ynm:A
74 5kh0:A 363 99 0.0977 0.0689 0.2525 6.9 5kh0:B, 5kh0:C, 5kh0:D
75 6jsj:A 625 56 0.0703 0.0288 0.3214 7.6 6jsj:B, 6jsj:C
76 8et3:C 353 112 0.1172 0.0850 0.2679 8.0 8e7v:A, 8e7v:B, 8e7v:C, 8e7v:D, 8e7v:E, 8e7v:F, 8e8q:A, 8e8q:B, 8e8q:C, 8e8q:D, 8e8q:E, 8e8q:F, 8e91:A, 8e91:B, 8e91:C, 8e91:D, 8e91:E, 8e91:F, 8et3:A, 8et3:B, 8et3:D, 8et3:E, 8et3:F, 6po1:A, 6po1:B, 6po1:C, 6po1:D, 6po1:E, 6po3:A, 6po3:B, 6po3:C, 6po3:D, 6po3:E, 6po3:F, 6pod:B, 6pod:C, 6pod:D, 6pod:E, 6pod:F, 6pos:B, 6pos:A, 6pos:C, 6pos:D, 6pos:E, 6pos:F, 6pp5:A, 6pp5:B, 6pp5:C, 6pp5:D, 6pp5:E, 6pp6:A, 6pp6:B, 6pp6:C, 6pp6:D, 6pp6:E, 6pp6:F, 6pp7:B, 6pp7:C, 6pp7:D, 6pp7:E, 6pp7:F, 6pp8:B, 6pp8:A, 6pp8:C, 6pp8:D, 6pp8:E, 6pp8:F, 6wrf:B, 6wrf:C, 6wrf:A, 6wrf:D, 6wrf:E, 6wrf:F, 6wsg:B, 6wsg:C, 6wsg:D, 6wsg:E, 6wsg:F
77 1tq6:A 402 30 0.0508 0.0323 0.4333 9.0 5fph:A, 5fph:B, 5fph:C, 5fph:D, 5fph:E, 5fph:F, 5fph:G, 4lv5:B, 4lv8:B, 1tpz:A, 1tpz:B, 1tq2:A, 1tq2:B, 1tq4:A
78 7olc:LT 158 30 0.0508 0.0823 0.4333 9.0 8i9p:LT, 8i9r:LT, 8i9t:LT, 8i9v:LT, 8i9w:LT, 8i9x:LT, 8i9y:LT, 8i9z:LT, 8ia0:LT, 7old:LT, 8oo0:LT, 8pv1:LT, 8pv2:LT, 8pv3:LT, 8pv4:LT, 8pv5:LT, 8pv6:LT, 8pv7:LT, 8pv8:LT, 8pvk:LT, 8pvl:LT, 7z3n:LT, 7z3o:LT
79 8wiv:D 602 63 0.0938 0.0399 0.3810 9.5 8wk0:D
80 5z2g:A 477 77 0.0781 0.0419 0.2597 9.8 5z2g:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218