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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VREEIESLVQDSLMEMVKGVKNTIESDLASKKGLAQSTTEILQLDPTNKAFAKSVLESPNLKGSFLAIGLGYESDATVVE
NDDGWEPNADYDPRKRPWYVDAKRERKLVVTEPYVDISTKKIIISIGTPVYQQSNFVGAMFYDVELTQLAQLVNSVNLFD
AGYLFITTKDGVTIAHPNAENNGEKFSQFLPNVDLKEGTQRIELDGKYYLVKFAQVPSESWYIGAVVDESIAFAMVD

The query sequence (length=237) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ior:A 241 237 1.0000 0.9834 1.0000 2.05e-176 6iop:A, 6iop:B, 6ioq:A, 6ior:B, 6ior:C, 6ior:D, 6ios:A, 6iot:A, 6iot:B, 6iot:C, 6iot:D, 6iou:A, 6iou:B
2 5ave:A 252 239 0.4388 0.4127 0.4351 3.12e-71 5avf:A, 5avf:B, 3c8c:A, 3c8c:B, 6iov:A, 6iov:B
3 5ltx:A 243 241 0.3291 0.3210 0.3237 1.70e-34 5ltx:B, 5t65:A, 5t65:B, 5t7m:A, 5t7m:B
4 5lt9:B 253 233 0.2869 0.2688 0.2918 7.14e-28 5lt9:A, 5lto:A, 5lto:B
5 6py3:B 238 244 0.3165 0.3151 0.3074 5.70e-27 6pxy:A, 6py3:A, 6py4:A, 6py5:A, 6pyi:A, 6q0f:A, 6q0g:A
6 5ltv:D 226 232 0.2911 0.3053 0.2974 4.58e-26 5ltv:A, 5ltv:B, 5ltv:E
7 7k5n:A 237 151 0.1730 0.1730 0.2715 2.03e-10
8 6mni:A 258 153 0.1772 0.1628 0.2745 8.63e-08 6mni:B
9 8bmv:B 249 168 0.1603 0.1526 0.2262 2.35e-06 8bmv:A
10 6w3o:B 252 64 0.0717 0.0675 0.2656 0.007 6w3o:A, 6w3p:A, 6w3p:B, 6w3r:A, 6w3r:B, 6w3s:A, 6w3s:B, 6w3t:A, 6w3t:B, 6w3v:A, 6w3v:B, 6w3x:A, 6w3x:B, 6w3y:A, 6w3y:B, 4xmr:A, 4xmr:B
11 8if3:A 917 101 0.1013 0.0262 0.2376 0.11
12 8x90:B 964 97 0.0970 0.0239 0.2371 0.12 8e59:D, 8e5a:D, 8e5b:D, 8epl:C, 8epm:C, 8fhs:D, 7mix:D, 7miy:D, 7uhf:D, 7uhg:D, 8we6:D, 8we7:D, 8we8:D, 8we9:D, 8wea:D, 8x91:B, 8x93:B
13 8e56:F 973 97 0.0970 0.0236 0.2371 0.13 8e57:F, 8e58:F, 8eog:D, 8fd7:D, 5gjw:F, 6jp5:F, 6jpa:F, 6jpb:F, 7vfs:B, 7vfu:B, 7vfv:B, 7vfw:B, 7xlq:D, 7yg5:D
14 6g18:v 325 205 0.1941 0.1415 0.2244 0.78 6fdm:A, 6fdm:C, 6g51:v, 6hk6:A, 6hk6:B, 6hk6:I, 6hk6:C, 6hk6:D, 6hk6:E, 6hk6:F, 6hk6:G, 6hk6:H, 6hk6:J, 7vbt:A, 7vbt:B, 7wu0:v
15 8he5:O 516 82 0.0759 0.0349 0.2195 1.5
16 8ro0:W 496 97 0.1055 0.0504 0.2577 1.7 8ro1:W
17 6tba:7A 292 33 0.0422 0.0342 0.3030 2.0 6tba:7C, 6tba:7B, 6teh:C
18 8tvy:M 558 39 0.0464 0.0197 0.2821 2.2 5vvr:M
19 4ov9:A 380 176 0.1730 0.1079 0.2330 4.0 4ov4:A
20 3q87:A 122 79 0.1055 0.2049 0.3165 4.1
21 9c20:A 451 92 0.1139 0.0599 0.2935 4.3 8url:A, 8uvv:A
22 7vdv:A 809 98 0.1139 0.0334 0.2755 6.1 7vdt:A
23 7y8r:I 732 98 0.1139 0.0369 0.2755 7.6
24 6rke:A 272 87 0.0844 0.0735 0.2299 7.7 4f6t:A, 6gu5:A, 6guj:A, 6gwb:A, 6gwv:A, 6gwv:P, 6gx4:A, 6h6w:A, 6h73:A, 6h74:A, 6h8b:A, 6h8h:A, 4ndo:A, 4ndp:A, 4ndq:A, 4ndr:A, 5o5w:A, 2ogx:A, 6ris:A, 6rj4:A, 6rj4:C, 6rj4:E, 6rkd:A, 6rkd:C, 6rkd:E, 6rkd:G, 6rkd:I, 6rkd:K, 6rke:C, 6rke:E, 6rke:G, 6rke:I, 6rke:K, 6yt3:A, 7z5j:A, 7z5j:C, 7z5j:E, 7z5j:I, 7z5j:G, 7z5j:K, 7zqq:A, 7zr4:A, 7zse:A
25 8b3f:b 534 39 0.0464 0.0206 0.2821 7.8 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218