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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VRARVISHALKDILAEGDKVIIMGHKRPDLDAIGAAIGVSRFAMMNNLEAYIVLNETDIDPTLRRVMNEIDKKPELRERF
ITSDDAWDMMTSKTTVVIVDTHKPELVLDENVLNKANRKVVIDHHRRESFISNPLLIYMEPYASSTAELVTELLEYQPTE
QRLTRLESTVMYAGIIVDTRNFTLRTGSRTFDAASYLRAHGADTILTQHFLKDDVDTYINRSELIRTVKVEDNGIAIAHG
SDDKIYHPVTVAQAADELLSLEGIEASYVVARREDNLIGISARSLGSVNVQLTMEALGGGGHLTNAATQLKGVTVEEAIA
QLQQAITEQLSR

The query sequence (length=332) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5xsi:A 333 333 1.0000 0.9970 0.9970 0.0 5xsi:B, 5xsn:A, 5xsn:B, 5xsp:A, 5xsp:B, 5xt3:A, 5xt3:B
2 8ioo:A 327 336 0.2470 0.2508 0.2440 5.49e-13 8ioo:B, 8ioo:C
3 3w5w:A 340 330 0.2470 0.2412 0.2485 1.26e-12
4 5o25:B 323 325 0.2349 0.2415 0.2400 6.54e-12 5o1u:A, 5o1u:B, 5o25:A, 5o4z:A, 5o58:A, 5o70:A, 5o7f:A, 5o7f:B
5 5izo:B 320 322 0.2590 0.2687 0.2671 1.94e-11 5ipp:A, 5ipp:C, 5iuf:A, 5iuf:B, 5izo:A, 5izo:C, 5izo:D
6 8iu7:B 323 329 0.2410 0.2477 0.2432 2.04e-11 8iu7:A, 8iu7:C, 8iu7:D
7 3dev:A 316 190 0.1476 0.1551 0.2579 3.98e-06 3dev:B
8 5cet:A 328 326 0.2380 0.2409 0.2423 9.52e-05 5jju:A, 5jju:B
9 1k20:A 310 170 0.1325 0.1419 0.2588 2.28e-04 1k20:B, 1wpp:A, 1wpp:B
10 2eb0:B 307 133 0.1114 0.1205 0.2782 3.07e-04 2eb0:A
11 4rpa:A 308 130 0.1145 0.1234 0.2923 3.52e-04 4rpa:B
12 2enx:A 310 135 0.1024 0.1097 0.2519 0.007 2enx:B
13 1i74:A 309 163 0.1114 0.1197 0.2270 0.036 1i74:B
14 5olp:A 432 57 0.0723 0.0556 0.4211 0.12 5olp:B
15 4ls9:A 319 307 0.2139 0.2226 0.2313 0.14 4ls9:B
16 1k23:D 231 177 0.1235 0.1775 0.2316 0.53
17 2haw:B 308 177 0.1235 0.1331 0.2316 0.71 2haw:A, 2iw4:A, 2iw4:B, 1k23:A, 1k23:B, 1k23:C, 1wpm:A, 1wpm:B, 1wpn:A, 1wpn:B
18 8rjf:A 424 95 0.0753 0.0590 0.2632 1.9 8rjf:B, 8rjf:C, 8rjf:D, 8rjf:E, 8rjf:F, 8rkd:F, 8rkd:A, 8rkd:C, 8rkd:D
19 6ll7:A 306 174 0.1114 0.1209 0.2126 2.9 6ll7:B, 6ll7:C, 6ll7:D, 6ll8:A, 6ll8:B
20 2ji6:A 559 51 0.0482 0.0286 0.3137 4.3 2c31:A, 2c31:B, 2ji6:B, 2ji7:A, 2ji7:B, 2ji8:A, 2ji8:B, 2ji9:A, 2ji9:B, 2jib:A, 2jib:B
21 8ijg:C 250 28 0.0392 0.0520 0.4643 4.7 8ij6:A, 8ij6:B, 8ij6:C, 8ij6:D, 8ijg:A, 8ijg:B, 8ijg:D
22 4wa6:D 415 109 0.0934 0.0747 0.2844 5.2 4w4u:D
23 8ki6:A 1580 34 0.0422 0.0089 0.4118 5.7
24 8ki8:A 1621 34 0.0422 0.0086 0.4118 6.0
25 7pua:F5 620 101 0.0813 0.0435 0.2673 6.8
26 8ki7:A 2003 34 0.0422 0.0070 0.4118 6.9
27 8hub:B 545 62 0.0572 0.0349 0.3065 7.4
28 8hu6:B 629 62 0.0572 0.0302 0.3065 7.7 8hu6:A, 8hu6:C, 8hu6:D
29 8hub:C 572 62 0.0572 0.0332 0.3065 7.8 8hub:D
30 2mkk:A 213 61 0.0663 0.1033 0.3607 9.3
31 5xwm:D 368 92 0.0693 0.0625 0.2500 9.7 5xwm:A, 5xwm:C, 5xwm:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218