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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VPTPAEAALAAQTALAADDSPMGDAARWAMGLLTSSGEDVAARFIPTFAAAGNFAETVREWRSKGPFTVRAYHPVAHKGW
VVLSAPAGVRYILSLTLDSSGLIRILTLKPETVIPDMVTWNDVEETLHTPGVQHSVYAVRLTPDGHEVLHASAPERPMPT
GSAYKLYLMRALVAEIEKGTVGWDEILTLTPELRSLPTGDMQDLPDGTRVTVRETAHKMIALSDNTGADLVADRLGREVV
ERSLAAAGHHDPSLMRPFLTSHEVFELGWGDPERRAEWVRQDEAGRRELLEKMAGVMTVRGSDLGATVHQLGIDWHMDAF
DVVRVLEGLLQDSGRDTSGTVEEILTAYPGLLIDEERWRRVYFKAGSSPGVMMFCWLLQDHAGISYVLVLRQSADEQRLI
GDGLFLRGIGAKIIEAEAKLLSS

The query sequence (length=423) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xf3:B 428 427 1.0000 0.9883 0.9906 0.0 2xf3:A, 2xfs:A, 2xfs:B, 2xh9:A, 2xh9:B
2 2jbf:D 274 79 0.0591 0.0912 0.3165 6.40e-06 2j8y:A, 2j8y:B, 2j8y:C, 2j8y:D, 2jbf:A, 2jbf:B, 2jbf:C
3 2v1z:A 270 129 0.0827 0.1296 0.2713 0.004 1axb:A, 1bt5:A, 8de0:A, 8de0:B, 8de0:C, 8de0:D, 8de1:A, 8de1:B, 8de1:C, 8de1:D, 8de2:A, 8de2:B, 8de2:C, 8de2:D, 1erm:A, 1ero:A, 1erq:A, 1esu:A, 1fqg:A, 1jvj:A, 1jwv:A, 1jwz:A, 1li0:A, 1m40:A, 1nxy:A, 1ny0:A, 1nym:A, 1nyy:A, 4opz:A, 4oq0:A, 4oqg:A, 4oqg:B, 4oqg:C, 4oqg:D, 4oqg:F, 4oqh:A, 1pzo:A, 1pzp:A, 7qlp:A, 7qlp:C, 7qlp:D, 7qlp:E, 7qnk:A, 7qnk:B, 7qnk:C, 7qnk:D, 7qnk:E, 4rva:A, 1tem:A, 2v20:A, 1xpb:A
4 4dxb:A 637 135 0.0827 0.0549 0.2593 0.11 4dxb:B, 4dxc:A
5 8of9:A 254 80 0.0567 0.0945 0.3000 0.61 8rqu:B
6 8he1:A 225 127 0.0780 0.1467 0.2598 0.91 8he2:A, 8he4:A, 8hf9:A
7 5zqa:A 248 110 0.0615 0.1048 0.2364 1.2 5zqb:A, 5zqb:B, 5zqb:C, 5zqb:D, 5zqc:A, 5zqc:B, 5zqc:C, 5zqc:D, 5zqd:A, 5zqd:B, 5zqd:C, 5zqd:D, 5zqd:E, 5zqd:F, 5zqd:G, 5zqd:H, 5zqe:A, 5zqe:B, 5zqe:C, 5zqe:D, 5zqe:E, 5zqe:F, 5zqe:G, 5zqe:H
8 4mf6:A 240 98 0.0709 0.1250 0.3061 1.2 4mf5:A
9 7q8b:A 370 97 0.0591 0.0676 0.2577 4.2 8c47:A, 7q8b:B, 7q8b:C, 7q8b:D, 7q8b:E, 7q8c:A, 7q8c:B, 7q8c:C, 7q8c:D, 7q8c:E, 7q8s:A, 7q8s:C, 7q8s:D, 7q8s:E, 7q8s:F
10 2xgf:A 216 38 0.0331 0.0648 0.3684 5.3 2xgf:B, 2xgf:C
11 4pl7:A 382 54 0.0449 0.0497 0.3519 5.5 4pl7:B, 7zvw:B
12 2ik0:B 286 112 0.0615 0.0909 0.2321 6.2 117e:A, 117e:B, 1e6a:A, 1e6a:B, 1e9g:A, 1e9g:B, 1huj:A, 1huj:B, 1huk:A, 1huk:B, 2ihp:A, 2ihp:B, 2ik0:A, 2ik1:A, 2ik1:B, 2ik2:A, 2ik2:B, 2ik4:A, 2ik4:B, 2ik6:A, 2ik6:B, 2ik7:A, 2ik7:B, 2ik9:A, 1m38:A, 1m38:B, 8prk:A, 8prk:B, 1wgi:A, 1wgi:B, 1wgj:A, 1wgj:B, 1ypp:A, 1ypp:B
13 8ccn:A 372 54 0.0449 0.0511 0.3519 6.6 4cbx:A, 8ccn:B, 8ccn:C, 8ccn:D, 8ccn:E, 8ccn:F, 8cco:A, 8cco:B, 8cco:C, 8cco:D, 8cco:E, 8cco:F, 6i4m:A
14 1c0g:A 368 54 0.0449 0.0516 0.3519 7.0 1dej:A, 8xvg:K, 8xvt:K
15 5f83:A 268 85 0.0567 0.0896 0.2824 7.8 5f83:B, 4gog:A, 4gog:B, 4h8r:A, 4h8r:B, 3nia:A, 6q35:A, 6q35:B, 4qu3:A, 4qu3:B, 8v9g:A, 8v9g:B, 8v9h:A, 8v9h:B
16 6xm7:A 488 44 0.0331 0.0287 0.3182 8.9 6xm6:A, 6xm8:A, 6xm9:A, 6xma:A
17 5xyi:J 162 72 0.0496 0.1296 0.2917 9.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218