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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYTGSGSADQTLTNMN
RALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDD
VEPAPWTSEGIERSRRLCLRLQYPAGY

The query sequence (length=187) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4pw7:E 198 194 1.0000 0.9444 0.9639 1.13e-135 4pw5:A, 4pw5:B, 4pw5:E, 4pw5:F, 4pw6:A, 4pw6:B, 4pw7:A, 4pw7:B, 4pw7:F
2 3clz:B 210 198 0.7540 0.6714 0.7121 1.53e-99 3clz:A, 3clz:C, 3clz:D, 8jig:A, 8jig:B, 6vcs:A, 6vcs:B, 6vcs:E
3 2zkd:A 210 197 0.7380 0.6571 0.7005 2.98e-97 3f8i:A, 3f8i:B, 3f8j:B, 3fde:A, 3fde:B, 6m2v:B, 6m2v:A, 2zkd:B, 2zke:A, 2zkf:A, 2zo0:B, 2zo1:B, 2zo2:B
4 6ghs:A 285 136 0.3262 0.2140 0.4485 5.34e-24
5 4ygi:A 150 173 0.3102 0.3867 0.3353 1.84e-20 3q0b:X, 3q0c:X, 3q0c:A, 3q0d:X, 3q0d:A, 3q0f:A, 3q0f:X
6 6a5n:A 502 160 0.2995 0.1116 0.3500 6.77e-19
7 6a5m:A 488 156 0.2941 0.1127 0.3526 1.77e-17 6a5k:A
8 4qen:A 472 182 0.2995 0.1186 0.3077 3.25e-13 4qeo:A, 4qep:A
9 4nj5:A 482 162 0.2620 0.1017 0.3025 2.25e-07
10 4dr0:B 291 120 0.1551 0.0997 0.2417 0.75 4dr0:A
11 6xyw:Bo 99 82 0.1123 0.2121 0.2561 1.3
12 7fd4:D 779 130 0.1818 0.0436 0.2615 4.9 7fd4:B, 7fd4:C, 7fd4:E, 7fd4:F, 7fd4:A, 7fd5:B, 7fd5:C, 7fd5:E, 7fd5:A, 7fd5:F, 7fd5:D, 7fid:D, 7fid:A, 7fid:B, 7fid:C, 7fid:E, 7fid:F, 7fie:B, 7fie:C, 7fie:D, 7fie:E, 7fie:A, 7fie:F, 7fiz:B, 7fiz:C, 7fiz:E, 7fiz:A, 7fiz:D, 7fiz:F, 8k3y:B, 8k3y:C, 8k3y:D, 8k3y:E, 6wqh:A, 6wqh:B, 6wqh:C, 6wqh:F, 6wqh:D, 6wqh:E, 4ypl:A, 4ypl:B, 4ypl:C, 4ypl:F, 4ypl:D, 4ypl:E, 4ypm:A, 7yph:B, 7yph:D, 7ypi:A, 7ypi:B, 7ypj:A, 7ypj:B, 7ypj:C, 7ypj:D, 7ypk:F, 7ypk:B, 7ypk:E, 7ypk:A, 7ypk:C, 7ypk:D, 7yuv:A, 7yuv:B, 7yuv:C, 7yuw:A, 7yuw:B, 7yuw:C, 7yuw:D, 7yux:A, 7yux:C, 7yux:E, 7yux:D, 7yux:B
13 5cfs:A 176 41 0.0695 0.0739 0.3171 5.0 5cft:A, 5cfu:A, 4wqk:A, 4wql:A, 4xje:A
14 2vn8:A 358 113 0.1444 0.0754 0.2389 7.4 2vn8:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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