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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VPQTHPHPDVDRVLLDEQQIRDRLAELGEQIAADYAEEPPVLVGVLRGAVMVMADLARQIDLKVEMDWMAVSSYGSGTKS
SGVVRILKDLSGDITDRNVLIVEDIIDSGLTLKWLLSNLRSRGPKSVEVAALLRKPDAARVDIDVKYIGFDIPSEFVIGY
GLDYAENYRNLPYVGVLSRSVYED

The query sequence (length=184) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4pfq:C 184 184 1.0000 1.0000 1.0000 2.80e-131 4pfq:A, 4pfq:B, 4pfq:D, 4pfq:E, 4pfq:F, 4pfq:G, 4pfq:H
2 3kb8:A 201 176 0.5163 0.4726 0.5398 1.18e-64 6d9r:A, 6d9r:B, 6d9s:A, 6d9s:B, 3h83:A, 3h83:B, 3kb8:B
3 5kny:B 187 181 0.5543 0.5455 0.5635 1.24e-56 5knp:A, 5knp:B, 5knp:C, 5knp:D, 5knq:A, 5knq:B, 5knq:C, 5knq:D, 5kny:A, 5kny:C, 5kny:D, 4rht:A, 4rht:B, 4rht:C, 4rht:D, 4rhu:A, 4rhu:B, 4rhu:C, 4rhu:D, 4rhu:E, 4rhu:F, 4rhx:A, 4rhx:B, 4rhx:C, 4rhx:D, 4rhy:A, 4rhy:B, 4rhy:C, 4rhy:D
4 2geb:A 184 177 0.5000 0.5000 0.5198 7.31e-56 1r3u:A, 1r3u:B, 1yfz:A, 1yfz:B
5 5knx:B 176 165 0.4620 0.4830 0.5152 3.96e-53 1g9s:A, 1g9s:B, 1g9t:A, 1g9t:B, 1grv:B, 1grv:A, 1j7j:A, 1j7j:B, 5knr:A, 5knr:B, 5kns:A, 5kns:B, 5knt:A, 5knt:B, 5knu:A, 5knu:B, 5knv:A, 5knv:B, 5knx:A
6 4qyi:B 171 167 0.3913 0.4211 0.4311 2.28e-51 4qyi:A, 4qyi:C, 4qyi:D, 4qyi:E
7 3acc:A 166 162 0.4076 0.4518 0.4630 2.42e-42 3acd:A
8 1hgx:A 164 171 0.3587 0.4024 0.3860 1.08e-38
9 7cmj:A 184 182 0.3696 0.3696 0.3736 2.31e-38 1pzm:A, 1pzm:B
10 1p17:B 204 184 0.4022 0.3627 0.4022 6.68e-36 1i0i:A, 1i0i:B, 1i0l:A, 1i0l:B, 1i13:A, 1i13:B, 1i14:A, 1i14:B, 1p17:A, 1p17:C, 1p17:D, 1p18:A, 1p18:B, 1p19:A, 1p19:B, 1p19:C, 1p19:D, 1tc1:A, 1tc1:B, 1tc2:A, 1tc2:B
11 6igs:B 167 166 0.3207 0.3533 0.3554 1.75e-34 6igs:A, 6igs:C, 6igs:D
12 1bzy:A 214 188 0.3750 0.3224 0.3670 2.79e-28 6bnj:A, 6bnj:B, 6bnj:C, 6bnj:D, 5brn:A, 5brn:C, 5brn:D, 1bzy:B, 1bzy:C, 1bzy:D, 1d6n:A, 1d6n:B, 3gep:A, 3gep:B, 3ggc:A, 3ggc:B, 3ggj:A, 3ggj:B, 5hia:A, 5hia:B, 5hia:C, 5hia:D, 1hmp:A, 1hmp:B, 4ijq:A, 4ijq:B, 4ijq:C, 4ijq:D, 4rab:A, 4rab:B, 4rab:C, 4rab:D, 4rac:A, 4rac:B, 4rac:C, 4rac:D, 4rad:A, 4rad:B, 4rad:C, 4rad:D, 4rad:E, 4rad:F, 4rad:G, 4rad:H, 4ran:A, 4ran:B, 4ran:C, 4ran:D, 4rao:A, 4rao:B, 4rao:C, 4rao:D, 4raq:A, 4raq:B, 4raq:C, 4raq:D, 7san:A, 7san:B, 7san:C, 7san:D, 8tpv:A, 8tpv:B, 8tpv:C, 8tpv:D, 5w8v:A, 5w8v:B, 5w8v:C, 5w8v:D
13 5ipf:A 201 181 0.3696 0.3383 0.3757 3.81e-26 5ipf:B, 5ipf:C, 5ipf:D
14 2jbh:B 213 188 0.3533 0.3052 0.3457 4.66e-25 2jbh:A
15 5brn:B 194 178 0.3478 0.3299 0.3596 5.19e-25 5bsk:A, 5bsk:B, 5bsk:C, 5bsk:D, 4kn6:A, 8tpy:A, 8tpy:B, 8tpy:C, 8tpy:D
16 6aps:A 185 178 0.3098 0.3081 0.3202 7.49e-24 6aps:B, 6apt:A, 6apt:B, 6apu:A, 6apu:B, 6apv:A, 6apv:B, 6apv:C, 6apv:D, 5jsq:A, 5jsq:B, 5jv5:A, 5jv5:B, 5k51:A, 5k51:B, 5k51:C, 5k51:D, 5kam:A, 5kam:C, 5kap:A, 5kap:B, 6mxg:A, 6mxg:B, 7sb7:A, 7sb7:B, 8tr1:A, 8tr1:B, 8tr1:C, 8tr1:D, 8ts4:A, 8ts4:B
17 6mxc:C 220 197 0.2989 0.2500 0.2792 1.15e-20 6aqo:A, 6aqo:B, 6aqo:C, 6aqo:D, 6aqo:E, 6aqo:F, 6ar9:A, 6ar9:B, 6ar9:C, 6ar9:D, 6ar9:E, 6ar9:F, 6mxb:A, 6mxb:B, 6mxb:C, 6mxb:D, 6mxb:E, 6mxb:F, 6mxc:A, 6mxc:B, 6mxc:D, 6mxc:E, 6mxc:F, 6mxd:A, 6mxd:B, 6mxd:C, 6mxd:D, 7scr:A, 7scr:C, 7scr:B, 7scr:D, 7scr:E, 7scr:F
18 2vfa:B 205 183 0.3207 0.2878 0.3224 1.84e-20 2vfa:A
19 8fx3:B 223 146 0.2446 0.2018 0.3082 1.48e-19 8fwy:A, 8fwy:B, 8fwz:A, 8fwz:B, 8fx0:A, 8fx0:B, 8fx1:A, 8fx1:B, 8fx2:A, 8fx2:B, 8fx3:A
20 1fsg:A 233 186 0.2772 0.2189 0.2742 6.30e-18 1dbr:A, 1dbr:B, 1dbr:D, 1fsg:C, 1qk3:A, 1qk3:B, 1qk3:C, 1qk3:D, 1qk4:A, 1qk4:B, 1qk4:C, 1qk4:D, 1qk5:A, 1qk5:B
21 3ozf:B 234 179 0.2772 0.2179 0.2849 1.58e-16 1cjb:A, 1cjb:B, 1cjb:C, 1cjb:D, 3ozf:A, 3ozf:C, 3ozf:D, 3ozg:A, 3ozg:B, 3ozg:C, 3ozg:D, 7tux:A, 7tux:B, 7tux:C, 7tux:D
22 5esw:A 190 165 0.2228 0.2158 0.2485 9.13e-16 5esx:A, 5esx:B
23 6bo7:A 220 179 0.2609 0.2182 0.2682 5.64e-15 6bo7:B, 6bo7:C, 6bo7:D, 6bo7:E, 6bo7:F, 6bo7:G, 6bo7:H, 6bo7:I, 6bo7:J, 6bo7:K, 6bo7:L
24 4trb:B 209 157 0.2500 0.2201 0.2930 1.56e-05 4trc:A, 4trc:B, 4ts5:A, 4ts5:B, 4ts7:A, 4ts7:B
25 1dqn:A 230 128 0.1957 0.1565 0.2812 2.39e-05 1dqn:B, 1dqp:A, 1dqp:B
26 4p86:A 177 150 0.2283 0.2373 0.2800 3.35e-05 4p86:B, 4p86:C, 4p86:D
27 4zfn:B 177 132 0.2011 0.2090 0.2803 0.001 5bqp:A, 5bqp:B, 5bqp:C, 5bqp:D, 4z1o:A, 4z1o:B, 4zfn:A
28 7kl6:A 147 135 0.1848 0.2313 0.2519 0.006
29 6asv:C 311 36 0.0815 0.0482 0.4167 0.11 6asv:A, 6asv:B, 4s2u:A, 7xmu:A, 7xmu:F, 7xmu:C, 7xmu:D, 7xmu:B, 7xmu:E, 7xmv:A, 7xmv:F, 7xmv:C, 7xmv:E, 7xmv:B, 7xmv:D, 7xn3:A, 7xn3:E, 7xn3:C, 7xn3:B, 7xn3:D, 7xn3:F
30 1i5e:A 208 51 0.0707 0.0625 0.2549 0.24 1i5e:B
31 6nfe:B 299 88 0.1304 0.0803 0.2727 0.27 6nfe:A
32 1ecf:B 500 72 0.1141 0.0420 0.2917 0.28 6czf:A, 6czf:C, 6czf:B, 6czf:D, 1ecb:A, 1ecb:B, 1ecb:C, 1ecb:D, 1ecc:A, 1ecc:B, 1ecf:A, 1ecg:A, 1ecg:B, 1ecj:A, 1ecj:C, 6ott:A, 6ott:B, 8w7d:A, 8w7d:B, 8w7d:C, 8w7d:D
33 1u9z:A 274 40 0.0815 0.0547 0.3750 0.30 1u9z:B, 1u9z:C, 1u9z:D
34 2igb:B 173 148 0.1793 0.1908 0.2230 0.38 2igb:A, 4p83:A, 4p83:B, 4p83:C, 4p83:D, 1xz8:A, 1xz8:B, 1xzn:A, 1xzn:B
35 5iao:A 171 66 0.1033 0.1111 0.2879 0.39 5iao:C, 5iao:F
36 7m8q:A 515 130 0.1685 0.0602 0.2385 2.1 6d7k:A, 6d7k:E, 7m8q:E, 7m8r:A, 7m8r:E, 1mhy:D, 1mhz:D, 7s6q:A, 7s6q:E, 7s6r:A, 7s6r:E, 7s6s:A, 7s6s:E, 7s6t:A, 7s6t:E, 7s7h:A, 7s7h:E, 6vk4:A, 6vk4:E, 6vk5:A, 6vk5:E, 6vk6:A, 6vk7:A, 6vk8:A, 6vk8:E, 6yd0:D, 6ydi:D, 6ydu:D, 6yy3:D
37 3mbi:A 287 40 0.0761 0.0488 0.3500 2.3 3lpn:A, 3lpn:B, 3lrt:A, 3lrt:B, 3mbi:C, 3mbi:B, 3mbi:D, 3nag:A, 3nag:B
38 4x8x:B 393 64 0.1087 0.0509 0.3125 2.3 4x8x:A, 4x9f:A
39 4xb8:A 391 64 0.1087 0.0512 0.3125 2.3 4xb8:B
40 3dah:C 300 43 0.0707 0.0433 0.3023 2.6 3dah:A, 3dah:B
41 5vog:A 176 64 0.1033 0.1080 0.2969 5.5
42 3boy:A 147 56 0.1033 0.1293 0.3393 6.3 3boy:B, 3boy:C, 4h4l:A, 4h4l:B, 4h4l:C, 4h4l:D, 4h4l:E, 4h4l:F, 4h4l:G, 4h4l:H, 4h4l:I, 4h4l:J, 4h4l:K, 4h4l:L, 1vea:A, 1vea:B, 1wmq:A, 1wmq:B, 1wpu:A, 1wpu:B, 1wpv:A, 1wpv:C, 1wpv:B, 1wrn:A, 1wrn:C, 1wrn:B, 1wro:A, 1wro:C, 1wro:B, 1wrq:A, 1wrq:B
43 1uqw:A 487 42 0.0598 0.0226 0.2619 6.4 1uqw:B
44 5hei:A 246 96 0.1359 0.1016 0.2604 6.9 5hei:B, 5hei:C, 5hei:D, 5hei:E, 5hei:F, 5hei:G, 5hei:H
45 6mlt:A 603 36 0.0543 0.0166 0.2778 9.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218