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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VPNNEYVQHFKDMYAKIHNANNGYFSDEGIPYHAVETLMVEAPDYGHETTSEAFSYYMWLEAMNAKLTGDFSGFKKAWDV
TEKYIIPGETDQPSASMSNYDPNKPATYAAEHPDPSMYPSQLQFGAAVGKDPLYNELKSTYGTSQVYGMHWLLDVDNWYG
FGGATSTSPVYINTFQRGVQESCWETVPQPCKDEMKYGGRNGFLDLFTGDSQYATQFKYTNAPDADARAVQATYYAQLAA
KEWGVDISSYVAKSTKMGDFLRYSFFDKYFRKVGNSTQAGTGYDSAQYLLNWYYAWGGGISSNWSWRIGSSHNHFGYQNP
MAAWILSNTSDFKPKSPNAATDWNNSLKRQIEFYQWLQSAEGGIAGGASNSNGGSYQAWPAGTRTFYGMGYTPHPVYEDP
GSNEWFGMQAWSMQRVAEYYYSSKDPAAKSLLDKWAKWACANVQFDDAAKKFKIPAKLVWTGQPDTWTGSYTGNSNLHVK
VEAYGEDLGVAGSLSNALSYYAKALESSTDAADKVAYNTAKETSRKILDYLWASYQDDKGIAVTETRNDFKRFNQSVYIP
SGWTGKMPNGDVIQSGATFLSIRSKYKQDPSWPNVEAALANGTGVDMTYHRFWGQSDIAIAFGTYGTLFT

The query sequence (length=630) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4xwl:A 634 630 1.0000 0.9937 1.0000 0.0 4xwm:A, 4xwn:A
2 1f9d:A 629 633 0.6317 0.6328 0.6288 0.0 1f9o:A, 1fae:A, 1fbo:A, 1fbw:A, 1fce:A, 1g9g:A, 1g9j:A, 2qno:A
3 6d5d:A 627 633 0.6254 0.6284 0.6224 0.0 4el8:A, 4l0g:A, 4txt:A
4 1l1y:A 642 631 0.5746 0.5639 0.5737 0.0 1l1y:B, 1l1y:C, 1l1y:D, 1l1y:E, 1l1y:F, 1l2a:A, 1l2a:B, 1l2a:C, 1l2a:D, 1l2a:E, 1l2a:F, 5yj6:A
5 4fus:A 635 640 0.5413 0.5370 0.5328 0.0
6 4jjj:A 636 648 0.5302 0.5252 0.5154 0.0
7 7kw6:A 697 698 0.4952 0.4476 0.4470 0.0
8 5bv9:A 701 705 0.5048 0.4536 0.4511 0.0 5cvy:A, 5vma:A
9 2bka:A 231 92 0.0365 0.0996 0.2500 0.51
10 5n6n:C 698 137 0.0460 0.0415 0.2117 1.1 5m4a:A
11 3p5r:A 750 48 0.0286 0.0240 0.3750 1.2 3p5p:A, 3p5r:B
12 4gfr:A 529 129 0.0651 0.0775 0.3178 2.7 8i5j:A, 8i5j:B, 8i5k:A, 1zu0:A
13 5iqc:A 301 52 0.0286 0.0598 0.3462 3.2 5byl:A, 5byl:B, 5byl:C, 5byl:D, 6c5u:A, 6c5u:B, 6c5u:C, 6c5u:D, 6cav:A, 6cav:B, 6cav:C, 6cav:D, 6cey:A, 6cey:B, 6cey:C, 6cey:D, 6cgd:A, 6cgd:B, 6cgd:C, 6cgd:D, 6cgg:A, 6cgg:B, 6cgg:C, 6cgg:D, 6ch4:A, 6ch4:B, 6ch4:C, 6ch4:D, 5iqa:A, 5iqa:B, 5iqa:C, 5iqa:D, 5iqb:A, 5iqb:B, 5iqb:C, 5iqb:D, 5iqc:B, 5iqc:C, 5iqc:D, 5iqd:A, 5iqd:B, 5iqd:C, 5iqd:D, 5iqe:A, 5iqe:B, 5iqe:C, 5iqe:D, 5iqf:A, 5iqf:B, 5iqf:C, 5iqf:D, 5iqg:A, 5iqg:B, 5iqg:C, 5iqg:D, 5iqh:A, 5iqh:B, 5iqh:C, 5iqh:D, 5iqi:A, 5iqi:B, 5iqi:C, 5iqi:D, 4ork:A, 4ork:B, 4ork:C, 4ork:D
14 6gmo:A 439 96 0.0365 0.0524 0.2396 4.7 6gmo:B, 2gwc:A, 2gwc:B, 2gwc:C, 2gwc:D, 2gwc:E, 2gwc:F, 2gwc:G, 2gwc:H, 2gwd:A
15 6ezl:A 392 55 0.0270 0.0434 0.3091 5.3 6ezl:B
16 2jkv:A 482 170 0.0683 0.0892 0.2529 8.6 2jkv:B, 2jkv:C, 2jkv:D, 2jkv:E, 2jkv:F, 1pgn:A, 1pgo:A, 1pgp:A, 1pgq:A, 5uq9:E, 5uq9:F
17 4tx6:B 310 63 0.0270 0.0548 0.2698 9.2 4tx6:A, 2xtk:A, 2xtk:B, 2xuc:A, 2xuc:B, 2xuc:C, 2xvn:A, 2xvn:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218