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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VNVVMTGDMTTRLAFAGEQLKQALVEKGYEVNKRSIYLNLLNKNKERFDISTKGKNTYVTGYDGNGIIYGCRELIDQLDQ
SGTMDFKPVSDAPEMVLRGACIGLQKTTYLPGHAVYEYPYTPESFPWFYDKERWIKYLDMMVENRMNSLYLWNGHPFASL
VKLKDYPFALEVDEETFKKNEEMFSFLTTEAEKRGIFVIQMFYNIIVSKPFADHYGIKTQDRNRPITPLISDYTRKSVAA
FIEKYPNVGLLVCLGEAIGTYEEDVEWFTKTIIPGIKDGLKVLGRTDEPPVLVRAHDTDCKMVIDAALPLYKNLYTMHKY
NGESLTTYEPRGPWAKIHKDLSSLGSVHISNVHILANLEPWRWSSPDFIQKSVKAMHSVHGANALHIYPQANYWDWPYTA
DKLANGEREEQVYRDWAWYKAWGRYAWKADRNRLEEIKYWDKQFGDFYGIPAEMADNIRIAYEESGEIAPKLLRRFGITE
GNRQTLLLGMFMSQFVNPYKYTIHYGFYESCGPGGEKLIEYVEKEWKKQPHVGELPLDIINQVIEHGDKAVAAIDKVVSS
AKKNSDELRRLQNDMHCYREYAYAFYYKVKAAQHVLNYHWGKNMDELDKAVPLMEESLKHYTKLVDLTKDTYLFANSMQT
AQRRIPIGGDDGNNKTWSEMLVHYKAELYNFKENIEMLKDKKVRKCVEVTPLKEADVKILNNLTKVKIEKGAKIFSNIDG
GIDAIAKEITGLTGFVFNGEKQRDDATTIEFECSSPVTMLVAYFKDDHRKFAKAPRLESDASANDYGQAEPVLTNALHVK
GVALADIYPYKFKAGRHTLILPKGYCGVLGFTEDKIKERDVAPDWLFY

The query sequence (length=848) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6hzf:A 860 859 1.0000 0.9860 0.9872 0.0 6hze:A, 6hze:B, 6hzf:B, 6hzg:A
2 8hvc:A 602 114 0.0342 0.0482 0.2544 0.56 8hvb:A, 8hvd:A
3 3rj8:A 473 76 0.0283 0.0507 0.3158 0.63 3rja:A
4 2vrq:A 493 72 0.0248 0.0426 0.2917 0.69 2vrq:B, 2vrq:C, 6zt7:A, 6zt7:B, 6zt7:C, 6zt9:A, 6zt9:B, 6zt9:C
5 1c7s:A 858 106 0.0259 0.0256 0.2075 1.3 1c7t:A
6 2v5d:A 722 182 0.0519 0.0609 0.2418 4.4 2cbi:A, 2cbi:B, 2cbj:A, 2cbj:B, 2j1a:A, 2j1e:A, 2j62:A, 2j62:B, 2j7m:A, 7khv:A, 7khv:B, 7khv:C, 7khv:D, 7khv:E, 7khv:F, 5oxd:A, 6rhe:A, 2v5c:A, 2v5c:B, 2vur:A, 2vur:B, 2wb5:A, 2wb5:B, 2x0y:A, 2x0y:B, 2xpk:A, 2xpk:B, 2ydq:A, 2ydr:A, 2yds:A, 4zxl:A
7 5vo3:A 380 65 0.0248 0.0553 0.3231 4.4 3ic1:A, 3ic1:B, 3isz:A, 3isz:B
8 3upt:A 671 70 0.0236 0.0298 0.2857 5.9 3upt:B
9 8ahu:A 283 51 0.0189 0.0565 0.3137 6.8 7p7x:A, 8raf:A, 8rai:A, 8yrt:A, 8yru:A, 8yrv:A
10 1hr6:D 443 107 0.0354 0.0677 0.2804 8.3 1hr6:B, 1hr6:F, 1hr6:H, 1hr7:B, 1hr7:D, 1hr7:F, 1hr7:H, 1hr8:B, 1hr8:D, 1hr8:F, 1hr8:H, 1hr9:B, 1hr9:D, 1hr9:F, 1hr9:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218