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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCK
VVGCSCVVVKDYGKESQAKDVIEE

The query sequence (length=104) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7a01:e3 124 113 1.0000 0.8387 0.9204 3.87e-68 7a09:v, 5a2q:M, 5aj0:BM, 9bdl:AS12, 9bdn:AS12, 9bdp:AS12, 8bhf:N3, 9bkd:m, 9bln:m, 8btk:Al, 4d5l:M, 4d61:M, 6d90:NN, 6d9j:NN, 9f1b:Al, 9f1c:Al, 9f1d:Al, 6fec:r, 5flx:M, 6g18:M, 6g51:M, 6g53:M, 6g5h:M, 6g5i:M, 8g5y:SM, 8g5z:SM, 8g60:SM, 8g61:SM, 8g6j:SM, 8glp:SM, 6gz3:BM, 6gz4:BM, 6gz5:BM, 6hcf:N1, 6hcj:N2, 6hcm:N1, 6hcq:N2, 8ifd:3J, 8ife:3J, 6ip5:3J, 6ip6:3J, 6ip8:3J, 3j7p:SM, 3j7r:SM, 3jag:MM, 3jah:MM, 3jai:MM, 3jaj:SM, 3jan:SM, 7jqb:N, 7jqc:N, 5k0y:r, 8k2c:SM, 7k5i:M, 4kzx:M, 4kzy:M, 4kzz:M, 5lks:SM, 7ls1:M3, 7ls2:M3, 5lzs:MM, 5lzt:MM, 5lzu:MM, 5lzv:MM, 5lzw:MM, 5lzx:MM, 5lzy:MM, 5lzz:MM, 7mdz:MM, 7mq8:LA, 7mq9:LA, 7mqa:LA, 6mtb:MM, 6mtc:MM, 6mtd:MM, 6mte:MM, 7nwg:N2, 7nwh:MM, 7nwi:MM, 7o7y:Al, 7o7z:Al, 7o80:Al, 7o81:Al, 5oa3:M, 6ole:SM, 6olf:SM, 6olg:BM, 6oli:SM, 6olz:BM, 6om0:SM, 6om7:SM, 8oz0:q, 8p03:O, 8p09:O, 8p2k:Al, 6p4g:N, 6p4h:N, 6p5i:N, 6p5j:N, 6p5k:N, 6p5n:N, 8pj1:m, 8pj2:m, 8pj3:m, 8pj4:m, 8pj5:m, 8pj6:m, 8ppk:M, 8ppl:AM, 8q7z:Al, 8q87:Al, 7qgg:SM, 8qoi:SM, 7qp6:m, 7qp7:m, 6qzp:SM, 7r4x:M, 6r5q:RR, 6r6g:RR, 6r6p:RR, 6r7q:RR, 8scb:MM, 6sgc:N1, 7syg:N, 7syh:N, 7syi:N, 7syj:N, 7syk:N, 7syl:N, 7sym:N, 7syn:N, 7syo:N, 7syp:N, 7syq:N, 7syr:N, 7sys:N, 7syt:N, 7syu:N, 7syv:N, 7syw:N, 7syx:N, 5t2c:AM, 8t4s:M, 7toq:AS12, 7tor:AS12, 7tql:O, 4ug0:SM, 4ujc:CM, 4ujd:CM, 4uje:BM, 4v6x:AM, 5vyc:M1, 5vyc:M2, 5vyc:M3, 5vyc:M4, 5vyc:M5, 5vyc:M6, 6w2s:N, 6w2t:N, 7wtt:M, 7wtu:M, 7wtv:M, 7wtw:M, 7wtx:M, 7wtz:M, 7wu0:M, 6xa1:SM, 7xnx:SM, 7xny:SM, 8xsx:SM, 8xsy:SM, 8xsz:SM, 8xxl:SM, 8xxm:SM, 8xxn:SM, 6y0g:SM, 6yal:O, 6yam:O, 6yan:O, 6ybs:m, 8yoo:SM, 8yop:SM, 6z6l:SM, 6z6m:SM, 6z6n:SM, 7zjw:SX, 7zjx:SX, 6zlw:O, 6zm7:SM, 6zme:SM, 6zmi:SM, 6zmo:SM, 6zmt:O, 6zmw:m, 6zn5:O, 6zoj:M, 6zol:M, 6zon:v, 6zp4:v, 6zuo:M, 6zv6:M, 6zvh:M, 6zvj:v, 6zvk:e3, 6zxd:M, 6zxe:M, 6zxf:M, 6zxg:M, 6zxh:M
2 7qvp:Rf 78 92 0.7500 1.0000 0.8478 5.10e-43 6y57:Sf
3 4v6w:AM 119 113 0.6731 0.5882 0.6195 6.46e-42 6xu6:AM, 6xu7:AM, 6xu8:AM
4 7olc:SM 118 108 0.6538 0.5763 0.6296 8.24e-42 7old:SM, 8oo0:SM, 7r81:N2, 7z3n:SM, 7z3o:SM
5 4v7e:BM 123 111 0.6154 0.5203 0.5766 1.88e-40 8r57:M
6 6zj3:SQ 122 111 0.6154 0.5246 0.5766 1.09e-35
7 9bh5:AM 117 110 0.5962 0.5299 0.5636 7.66e-34 9cai:AM
8 8c3a:CZ 119 112 0.5962 0.5210 0.5536 1.24e-33 8c3a:O, 8cq7:O, 8cq7:CZ, 8cqw:O, 8cqw:CZ, 8cre:O, 8cre:CZ, 8oeq:O, 8oeq:CZ, 7pzy:N, 7q08:N, 7q0f:N, 7q0p:N, 7q0r:N
9 8auv:C 117 113 0.5865 0.5214 0.5398 5.37e-30 8b2l:C1
10 7ase:h 121 108 0.4231 0.3636 0.4074 1.78e-24 5opt:i
11 8i7j:M 122 113 0.4904 0.4180 0.4513 2.76e-23 6fyx:M, 6fyy:M, 6gsm:M, 6gsn:M, 5it7:M, 5it9:M, 3j80:M, 3j81:M, 3jam:M, 3jap:M, 8rw1:M, 8s8d:M, 8s8e:M, 8s8f:M, 8s8g:M, 8s8h:M, 8s8i:M, 8s8j:M, 6uz7:M
12 4v8m:AF 121 108 0.4231 0.3636 0.4074 4.58e-23 8ova:AF
13 8cbj:M 125 83 0.4231 0.3520 0.5301 1.67e-22 7a1g:D, 7b7d:D, 8bqd:D, 8bqx:D, 8cah:D, 8cas:F, 7d5s:SN, 5dat:C2, 5dat:c2, 5dc3:C2, 5dc3:c2, 5dge:C2, 5dge:c2, 5dgf:C2, 5dgf:c2, 5dgv:C2, 5dgv:c2, 6eml:D, 8eub:BM, 8evp:BM, 8evq:BM, 8evr:BM, 8evs:BM, 8evt:BM, 8ewb:BM, 8ewc:BM, 6fai:M, 5fcj:C2, 5fcj:c2, 6gq1:AC, 6gqb:AC, 6gqv:AC, 6hhq:N, 6hhq:c2, 5i4l:C2, 5i4l:c2, 6i7o:D, 6i7o:Db, 3j6x:12, 3j6y:12, 3j77:12, 3j78:12, 5juo:JB, 5jup:JB, 5jus:JB, 5jut:JB, 5juu:JB, 8k2d:SM, 8k82:SM, 6ke6:SN, 6lqp:SN, 6lqu:SN, 5lyb:C2, 5m1j:M2, 5mc6:D, 5mei:c2, 5mei:N, 7mpi:BM, 7mpj:BM, 7n8b:BM, 5ndg:C2, 5ndg:c2, 5ndv:c2, 5ndw:C2, 5ndw:c2, 7nrc:SD, 7nrd:SD, 5obm:C2, 5obm:c2, 5on6:c2, 5on6:N, 7osa:eS12, 6q8y:D, 6rbd:M, 6rbe:M, 7rr5:SM, 6s47:BN, 6snt:M, 6sv4:D, 6sv4:Db, 6sv4:Dc, 6t4q:SM, 6t7i:SM, 6t7t:SM, 6t83:Mb, 6t83:n, 5tbw:N, 5tbw:c2, 6tb3:D, 5tga:C2, 5tga:c2, 5tgm:C2, 5tgm:c2, 6tnu:D, 4u3m:C2, 4u3m:c2, 4u3n:C2, 4u3n:c2, 4u3u:C2, 4u3u:c2, 4u4n:C2, 4u4n:c2, 4u4o:C2, 4u4o:c2, 4u4q:C2, 4u4q:c2, 4u4r:C2, 4u4r:c2, 4u4u:C2, 4u4u:c2, 4u4y:C2, 4u4y:c2, 4u4z:C2, 4u4z:c2, 4u50:C2, 4u50:c2, 4u51:C2, 4u51:c2, 4u52:C2, 4u52:c2, 4u53:C2, 4u53:c2, 4u55:C2, 4u55:c2, 4u56:C2, 4u56:c2, 4u6f:C2, 4u6f:c2, 4uer:U, 4v88:AM, 4v88:CM, 4v8y:AM, 4v8z:AM, 6wdr:M, 6woo:MM, 5wyj:SN, 6y7c:M, 6z6j:SM, 6z6k:SM, 6zce:N, 7zpq:AM, 7zrs:AM, 6zu9:F, 7zuw:AM, 7zux:DM, 6zvi:u, 7zw0:sD
14 6az1:Q 115 108 0.3942 0.3565 0.3796 1.74e-21 8ovj:SQ, 8rxh:SQ, 8rxx:SQ
15 5ndv:C2 102 103 0.4904 0.5000 0.4951 3.01e-20
16 5fci:C2 124 74 0.3942 0.3306 0.5541 7.61e-20 5fci:c2, 5lyb:c2
17 4bts:AU 124 104 0.3269 0.2742 0.3269 6.74e-16 4bts:BU, 4bts:CU, 4bts:DU, 4v5o:AU, 4v5o:BU
18 8fvy:M 103 73 0.2788 0.2816 0.3973 6.29e-11 8g4s:M
19 8p5d:SM0 113 105 0.2981 0.2743 0.2952 2.15e-08 8p60:SM0, 8p60:RM0, 7qca:SM0
20 5xyi:M 103 91 0.2692 0.2718 0.3077 3.81e-08
21 8hku:L7A1 123 98 0.3077 0.2602 0.3265 4.79e-07 8hku:L7A2, 8hkv:L7A1, 8hkv:L7A2, 8hkx:SL7A, 8hky:L7A1, 8hky:L7A2, 8hky:SL7A, 8hkz:L7A1, 8hkz:L7A2, 8hkz:SL7A, 8hl1:SL7A, 8hl1:L7A1, 8hl1:L7A2, 8hl2:L7A1, 8hl2:L7A2, 8hl2:SL7A, 8hl3:L7A1, 8hl3:L7A2, 8hl3:SL7A, 8hl4:L7A1, 8hl4:L7A2, 8hl4:SL7A, 8hl5:L7A1, 8hl5:L7A2, 8hl5:SL7A, 8wkp:SL7A, 8wq2:SL7A, 8wq4:SL7A
22 6rm3:SM0 119 107 0.2596 0.2269 0.2523 9.10e-07
23 6tmf:b 123 75 0.2404 0.2033 0.3333 1.14e-05
24 8rxh:LG 241 78 0.2308 0.0996 0.3077 1.71e-05 8a3w:G, 8a98:G, 6az3:G, 3jcs:G, 8ovj:G, 8rxx:LG, 5t2a:v
25 5gin:C 122 98 0.2692 0.2295 0.2857 5.40e-05 5gin:D, 5gin:L, 5gio:C, 5gio:D, 5gio:L, 5gip:C, 5gip:D, 5gip:M, 5gip:N, 3id5:C, 3id5:G, 5jpq:U, 5jpq:V, 3pla:C, 3pla:D, 3pla:L
26 4v8m:Bx 240 78 0.2212 0.0958 0.2949 7.00e-05 8ova:Bx, 8ove:Bx, 5t5h:x
27 5y7m:A 125 87 0.2500 0.2080 0.2989 1.82e-04 4by9:G, 4by9:J, 4by9:D, 4by9:M, 5dcv:A, 5dcv:C, 3hax:D, 3hay:D, 3hjw:C, 2hvy:D, 5jb3:3, 5jbh:3, 3lwo:C, 3lwp:C, 3lwq:C, 3lwr:C, 3lwv:C, 3nmu:G, 3nmu:C, 3nvi:B, 3nvi:D, 3nvk:E, 3nvk:H, 7ozq:B, 7ozq:D, 7ozq:C, 7ozq:A, 6skf:BH, 6skf:BI, 6skg:BH, 6skg:BI, 6sw9:3, 6swc:3, 6swe:3, 6th6:BH, 6th6:BI, 6tph:A, 4v4n:B3, 4v4n:AG, 4v6u:A3, 4v6u:BG, 4v6u:B4, 5xtm:A, 5xtm:C, 5y7m:C, 7zag:3, 7zah:3, 7zai:3, 7zhg:3
28 7qep:C2 118 97 0.2885 0.2542 0.3093 6.65e-04
29 6q8u:C 122 75 0.2115 0.1803 0.2933 0.001 4bw0:B, 4c4w:C, 4c4w:G, 5fj4:C, 5fj4:G, 5g4u:C, 5g4u:D, 5g4u:G, 5g4u:H, 5g4u:K, 5g4u:L, 5g4v:C, 5g4v:D, 5g4v:G, 5g4v:H, 6hct:C, 6hct:D, 6hct:G, 6q8u:D, 1rlg:A, 1rlg:B
30 2ale:A 132 75 0.1827 0.1439 0.2533 0.025 7ajt:CF, 7ajt:CG, 7aju:CF, 7aju:CG, 7d4i:3G, 7d4i:3H, 7d5s:3G, 7d5s:3H, 7d5t:3G, 7d5t:3H, 7d63:3G, 7d63:3H, 5gan:K, 5gap:K, 3jcm:M, 6ke6:3G, 6ke6:3H, 6lqp:3G, 6lqp:3H, 6lqq:3G, 6lqq:3H, 6lqr:3G, 6lqr:3H, 6lqs:3G, 6lqs:3H, 6lqt:3G, 6lqt:3H, 6lqu:3G, 6lqu:3H, 6lqv:3G, 6lqv:3H, 6nd4:e, 6nd4:f, 5nrl:K, 4nut:A, 7suk:SE, 7suk:SF, 5tzs:f, 5wlc:SE, 5wlc:SF, 5wyj:3G, 5wyj:3H, 5wyk:3G, 5wyk:3H, 6zqa:CF, 6zqb:CF, 6zqb:CG, 6zqc:CF, 6zqc:CG, 6zqd:CF, 6zqd:CG, 6zqe:CF, 6zqe:CG, 5zwm:M, 5zwo:M
31 6zu5:LG0 202 67 0.1731 0.0891 0.2687 0.082
32 6k0a:I 116 86 0.2308 0.2069 0.2791 0.29 6k0a:J, 6k0b:I, 6k0b:J, 1sds:A, 1sds:C, 1sds:B
33 5oql:V 121 66 0.1538 0.1322 0.2424 0.74 5oql:W, 6rxt:CE, 6rxt:CF, 6rxu:CE, 6rxu:CF, 6rxv:CE, 6rxv:CF, 6rxx:CE, 6rxx:CF, 6rxy:CE, 6rxy:CF, 6rxz:CE, 6rxz:CF
34 7qep:L8 197 67 0.1442 0.0761 0.2239 0.82
35 7xdv:A 283 46 0.1538 0.0565 0.3478 2.5 7xdv:B, 7xdw:A, 7xdw:B, 7xdx:A, 7xdx:B, 7xdy:A, 7xdy:B
36 1qz9:A 404 32 0.0962 0.0248 0.3125 2.9
37 6eji:A 360 30 0.1154 0.0333 0.4000 3.3 6eji:B, 6ejj:A, 6ejj:B, 6ejk:A, 6ejk:B
38 6rm3:LG0 195 63 0.1250 0.0667 0.2063 3.8
39 8q87:A 857 81 0.2596 0.0315 0.3333 3.9 6d9j:9, 6gz3:Ct, 6gz4:Ct, 6gz5:Ct, 3j7p:4, 7ls1:m, 7ls2:m, 6mtd:v, 6mte:v, 7oyc:v2, 4v6x:Az, 8xsx:CB, 6z6m:CB, 6z6n:CB
40 3ewd:A 364 66 0.1635 0.0467 0.2576 4.2 3ewc:A, 2pgf:A, 2pgr:A, 2qvn:A
41 6ttl:A 479 15 0.1058 0.0230 0.7333 4.7 6ttl:B
42 3jrv:B 144 31 0.1154 0.0833 0.3871 5.3 3jrv:A
43 6zj3:LV 238 71 0.1731 0.0756 0.2535 8.3
44 8fru:G 197 67 0.1635 0.0863 0.2537 8.6 8br8:LI, 8brm:LI, 8bsi:LI, 8bsj:LI, 8btd:LI, 8btr:LI, 7pwg:G, 7pwo:G2
45 3j79:J 229 59 0.1635 0.0742 0.2881 9.9 3jbn:AJ, 3jbo:AJ, 3jbp:AJ, 8tpu:AJ, 5umd:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218