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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQLGRIMLKGDNITLLQSVS

The query sequence (length=79) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7abg:j 81 79 1.0000 0.9753 1.0000 1.52e-54 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
2 8ro0:e 80 76 0.6456 0.6375 0.6711 2.89e-37 8ro1:e
3 3jb9:H 76 77 0.5190 0.5395 0.5325 9.86e-28 3jb9:m
4 7b9v:p 77 77 0.5063 0.5195 0.5195 6.83e-26 7b9v:e, 6bk8:c, 7dco:i, 6exn:p, 6exn:e, 6g90:e, 6g90:w, 5gan:p, 5gao:p, 5gm6:i, 5gmk:i, 5gmk:u, 6j6g:i, 6j6g:u, 6j6h:i, 6j6h:u, 6j6n:i, 6j6n:u, 6j6q:i, 6j6q:u, 5mps:e, 5mq0:e, 6n7p:O, 6n7r:O, 6n7x:O, 5nrl:w, 5nrl:p, 5nrl:e, 7oqb:w, 7oqc:e, 7oqe:w, 8w2o:O, 5wsg:i, 5wsg:G, 5y88:b, 5y88:i, 5ylz:b, 5ylz:i, 5zwm:T, 5zwm:i, 5zwn:e, 5zwo:T, 5zwo:i
5 1loj:C 77 40 0.2405 0.2468 0.4750 3.77e-06 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
6 1i5l:C 74 76 0.3165 0.3378 0.3289 2.88e-05 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
7 1m8v:A 72 69 0.2785 0.3056 0.3188 5.70e-05 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
8 8ro0:n 77 50 0.2025 0.2078 0.3200 7.01e-05 8ro0:g, 8ro1:g
9 3swn:A 76 73 0.2278 0.2368 0.2466 8.35e-05 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
10 6v4x:G 77 49 0.1772 0.1818 0.2857 1.27e-04 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
11 1lnx:A 74 67 0.2532 0.2703 0.2985 0.001 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
12 6qw6:68 95 51 0.2152 0.1789 0.3333 0.002 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
13 6v4x:B 76 40 0.1899 0.1974 0.3750 0.002
14 6exn:r 75 51 0.2152 0.2267 0.3333 0.002 7b9v:r, 7b9v:g, 6bk8:d, 7dco:k, 6exn:g, 6g90:g, 6g90:y, 5gam:g, 5gan:r, 5gan:g, 5gao:r, 5gm6:j, 5gmk:j, 5gmk:x, 6j6g:j, 6j6g:x, 6j6h:j, 6j6h:x, 6j6n:j, 6j6n:x, 6j6q:j, 6j6q:x, 5lj3:g, 5lj5:g, 5mps:g, 5mq0:g, 6n7p:Q, 6n7r:Q, 6n7x:Q, 5nrl:y, 5nrl:r, 5nrl:g, 7oqb:y, 7oqc:g, 7oqe:y, 8w2o:Q, 5wsg:j, 5wsg:K, 5y88:d, 5y88:k, 5ylz:d, 5ylz:k, 5zwm:V, 5zwm:k, 5zwn:g, 5zwo:k
15 6ppn:C 75 51 0.2152 0.2267 0.3333 0.002 6ppn:K, 6ppp:C, 6ppp:K, 6ppq:C, 6ppv:C
16 3jb9:E 98 44 0.2152 0.1735 0.3864 0.006 3jb9:b
17 8ro0:f 72 44 0.2025 0.2222 0.3636 0.007 8ro1:f
18 8ro0:d 94 74 0.2152 0.1809 0.2297 0.007 8ro1:d
19 7w59:b 102 49 0.2278 0.1765 0.3673 0.026 7abg:m, 7abi:m, 6ahd:a, 7b0y:j, 8c6j:b, 8ch6:8, 7dvq:i, 9fmd:i, 8h6e:5a, 8h6e:4a, 8h6j:5a, 8h6j:4a, 8h6k:5a, 8h6l:5a, 8i0p:a, 8i0p:m, 8i0r:a, 8i0r:m, 8i0s:m, 8i0t:a, 8i0t:m, 8i0u:m, 8i0v:a, 8i0v:m, 8i0w:a, 8i0w:i, 6icz:i, 4pjo:B, 4pjo:b, 4pjo:P, 4pjo:p, 8q7q:b, 8q7v:b, 8q7w:b, 8q7x:b, 8q91:h, 6qdv:k, 8qo9:5b, 8qo9:4b, 6qw6:4b, 6qw6:5b, 6qx9:1b, 6qx9:5b, 6qx9:2b, 6qx9:4b, 8qxd:4b, 8qxd:5b, 8qzs:5b, 8qzs:2b, 8r08:1b, 8r08:4b, 8r08:5b, 8r09:5b, 8r0a:5b, 8r0b:5b, 8rc0:h, 8rm5:2b, 8rm5:5b, 8ro2:b, 7vpx:k, 7w59:i, 7w5a:b, 7w5a:i, 7w5b:b, 7w5b:i, 4wzj:B, 5xjc:b, 5xjc:i, 8y6o:a, 8y6o:h, 8y6o:o, 8y7e:i, 5yzg:b, 5yzg:i, 5z56:b, 5z56:i, 5z57:b, 5z57:i, 5z58:b, 5z58:i
20 9fmd:b 87 41 0.1772 0.1609 0.3415 0.031 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
21 3jb9:J 73 60 0.1772 0.1918 0.2333 0.032 3jb9:o
22 6bk8:f 80 42 0.2278 0.2250 0.4286 0.059 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
23 8ro0:b 98 40 0.1646 0.1327 0.3250 0.077 8ro1:b
24 4m7a:F 66 47 0.2278 0.2727 0.3830 0.092
25 5vsu:C 81 82 0.2532 0.2469 0.2439 0.095 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
26 7b9v:q 75 40 0.1772 0.1867 0.3500 0.096 7b9v:f, 6bk8:b, 7dco:j, 6exn:q, 6exn:f, 6g90:f, 6g90:x, 5gam:f, 5gan:q, 5gan:f, 5gao:q, 5gm6:h, 5gmk:h, 5gmk:w, 6j6g:h, 6j6g:w, 6j6h:h, 6j6h:w, 6j6n:h, 6j6n:w, 6j6q:h, 6j6q:w, 5lj3:f, 5lj5:f, 5mps:f, 5mq0:f, 6n7p:P, 6n7r:P, 6n7x:P, 5nrl:x, 5nrl:q, 5nrl:f, 7oqc:f, 8w2o:P, 5wsg:h, 5wsg:H, 5y88:c, 5y88:j, 5ylz:c, 5ylz:j, 5zwm:U, 5zwm:j, 5zwn:f, 5zwo:U, 5zwo:j
27 6n7p:M 107 77 0.2278 0.1682 0.2338 0.13 7b9v:m, 7b9v:j, 6bk8:a, 7dco:n, 6exn:m, 6exn:j, 6g90:i, 6g90:u, 5gam:j, 5gan:m, 5gan:j, 5gao:m, 5gm6:g, 5gmk:g, 5gmk:e, 6j6g:g, 6j6g:e, 6j6h:g, 6j6h:e, 6j6n:g, 6j6n:e, 6j6q:g, 6j6q:e, 3jcm:Q, 3jcm:U, 5lj3:j, 5lj3:m, 5lj5:j, 5lj5:m, 5mps:j, 5mq0:j, 6n7r:M, 6n7x:M, 5nrl:u, 5nrl:m, 5nrl:i, 7oqb:u, 7oqc:i, 7oqe:i, 7oqe:u, 8w2o:M, 5wsg:g, 5wsg:W, 5y88:g, 5y88:n, 5ylz:g, 5ylz:n, 5zwm:R, 5zwm:c, 5zwm:n, 5zwn:c, 5zwo:c, 5zwo:R, 5zwo:n
28 8y6o:q 104 72 0.1899 0.1442 0.2083 0.15 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
29 3jb9:I 73 47 0.2025 0.2192 0.3404 0.24 3jb9:n
30 7pkt:v 120 51 0.1772 0.1167 0.2745 0.58
31 4wzj:MM 80 51 0.1772 0.1750 0.2745 0.62 7abg:b, 7abi:b, 6ahd:Q, 6ahd:d, 7b0y:f, 8c6j:q, 8c6j:f, 8ch6:h, 8ch6:2, 7dvq:f, 7dvq:m, 9fmd:m, 9fmd:f, 8h6e:5d, 8h6e:4d, 8h6j:5d, 8h6j:4d, 8h6k:5d, 8h6k:4d, 8h6l:5d, 8h6l:4d, 8i0p:d, 8i0r:d, 8i0s:d, 8i0s:i, 8i0t:d, 8i0t:i, 8i0u:d, 8i0u:i, 8i0v:d, 8i0v:i, 8i0w:d, 8i0w:m, 6id1:f, 5mqf:i, 5mqf:b, 5o9z:i, 4pjo:F, 4pjo:f, 4pjo:T, 4pjo:t, 8q7q:f, 8q7v:f, 8q7w:f, 8q7x:f, 8q91:m, 6qdv:q, 6qdv:f, 8qo9:2f, 8qo9:5f, 8qo9:4f, 7qtt:h, 6qw6:4f, 6qw6:5f, 6qx9:1f, 6qx9:5f, 6qx9:2f, 6qx9:4f, 8qxd:2f, 8qxd:4f, 8qxd:5f, 8qzs:5f, 8qzs:2f, 8qzs:4f, 8r08:1f, 8r08:2f, 8r08:4f, 8r08:5f, 8r09:2f, 8r09:5f, 8r09:4f, 8r0a:5f, 8r0a:2f, 8r0a:4f, 8r0b:2f, 8r0b:4f, 8r0b:5f, 8rc0:m, 8rm5:2f, 8rm5:5f, 8rm5:4f, 8ro2:f, 6v4x:F, 7vpx:m, 7w59:f, 7w59:m, 7w5a:f, 7w5a:m, 7w5b:f, 7w5b:m, 4wzj:F, 4wzj:M, 4wzj:T, 4wzj:FF, 4wzj:TT, 4wzj:FFF, 4wzj:MMM, 4wzj:TTT, 4wzj:FFFF, 4wzj:MMMM, 4wzj:TTTT, 5xjc:f, 5xjc:m, 8y6o:f, 8y6o:m, 8y6o:t, 8y7e:m, 5yzg:f, 5yzg:m, 5z56:m, 5z57:m, 5z58:m
32 6ppn:H 94 46 0.2025 0.1702 0.3478 0.78 6ppn:P, 6ppp:H, 6ppp:P
33 3jb9:G 95 81 0.2152 0.1789 0.2099 1.5 3jb9:l
34 6qw6:63 85 86 0.2152 0.2000 0.1977 2.7 6ah0:r, 6qx9:63, 8qxd:63, 8r08:63, 8r09:63, 8r0a:63, 8r0b:63, 8rm5:63
35 6qw6:66 72 45 0.1392 0.1528 0.2444 2.7 6qx9:66
36 4wzj:KK 104 48 0.1519 0.1154 0.2500 3.0 7abg:h, 7abi:h, 6ahd:c, 7b0y:e, 8c6j:m, 8c6j:a, 7evo:a, 9fmd:k, 9fmd:d, 8h6e:5c, 8h6e:4c, 8h6j:5c, 8h6j:4c, 8h6k:5c, 8h6l:5c, 8hk1:a, 8i0p:c, 8i0p:h, 8i0r:c, 8i0r:h, 8i0s:c, 8i0s:h, 8i0t:h, 8i0u:c, 8i0u:h, 8i0v:c, 8i0v:h, 8i0w:c, 6icz:d, 6id0:d, 6id1:d, 5mqf:h, 5mqf:a, 4pjo:D, 4pjo:d, 4pjo:r, 8q7q:c, 8q7v:c, 8q7w:c, 8q7x:c, 8q91:j, 6qdv:m, 6qdv:j, 8qo9:22, 8qo9:52, 8qo9:42, 6qw6:42, 6qw6:52, 6qx9:12, 6qx9:52, 6qx9:22, 6qx9:42, 8qxd:22, 8qxd:42, 8qxd:52, 8qzs:52, 8qzs:22, 8r08:12, 8r08:42, 8r08:22, 8r08:52, 8r09:22, 8r09:52, 8r09:42, 8r0a:52, 8r0a:42, 8r0a:22, 8r0b:22, 8r0b:42, 8r0b:52, 8rc0:j, 8rm5:22, 8rm5:52, 8rm5:42, 8ro2:d, 7vpx:a, 7vpx:i, 7w59:d, 7w5a:d, 7w5b:d, 4wzj:D, 4wzj:K, 4wzj:R, 4wzj:DD, 4wzj:RR, 4wzj:DDD, 4wzj:KKK, 4wzj:RRR, 4wzj:DDDD, 4wzj:KKKK, 4wzj:RRRR, 5xjc:d, 6y53:h, 6y5q:h, 8y6o:c, 8y6o:j, 5yzg:d, 5z56:d, 5z57:d, 5z58:d
37 6n7r:K 124 43 0.1899 0.1210 0.3488 3.5 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
38 6ppq:F 71 47 0.1646 0.1831 0.2766 3.7 6ppn:F, 6ppn:N, 6ppp:F, 6ppp:N, 6ppv:F
39 6ipw:A 221 26 0.1013 0.0362 0.3077 6.0 6ipw:B, 6ipw:C, 6ipw:D
40 8bdb:A 480 30 0.1266 0.0208 0.3333 6.1 8bdb:C, 8bdb:E, 8bdb:G, 8bdb:I, 8bdb:K, 8bdb:M, 8bdb:O
41 5nv3:A 467 42 0.1646 0.0278 0.3095 6.1 5nv3:E, 5nv3:B, 5nv3:F, 5nv3:C, 5nv3:G, 5nv3:D, 5nv3:H
42 6s6b:I 284 46 0.1899 0.0528 0.3261 8.3 6s8b:I, 6s8e:I, 6s91:I, 6sh8:I, 6shb:I, 6sic:I
43 2okj:B 504 27 0.1139 0.0179 0.3333 8.7 2okj:A, 3vp6:A, 3vp6:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218