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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
VMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVG
LCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK

The query sequence (length=122) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 7a01:e3 124 122 1.0000 0.9839 1.0000 5.56e-86 7a09:v, 5a2q:M, 5aj0:BM, 9bdl:AS12, 9bdn:AS12, 9bdp:AS12, 8bhf:N3, 9bkd:m, 9bln:m, 8btk:Al, 4d5l:M, 4d61:M, 6d90:NN, 6d9j:NN, 9f1b:Al, 9f1c:Al, 9f1d:Al, 6fec:r, 5flx:M, 6g18:M, 6g51:M, 6g53:M, 6g5h:M, 6g5i:M, 8g5y:SM, 8g5z:SM, 8g60:SM, 8g61:SM, 8g6j:SM, 8glp:SM, 6gz3:BM, 6gz4:BM, 6gz5:BM, 6hcf:N1, 6hcj:N2, 6hcm:N1, 6hcq:N2, 8ifd:3J, 8ife:3J, 6ip5:3J, 6ip6:3J, 6ip8:3J, 3j7p:SM, 3j7r:SM, 3jag:MM, 3jah:MM, 3jai:MM, 3jaj:SM, 3jan:SM, 7jqb:N, 7jqc:N, 5k0y:r, 8k2c:SM, 7k5i:M, 4kzx:M, 4kzy:M, 4kzz:M, 5lks:SM, 7ls1:M3, 7ls2:M3, 5lzs:MM, 5lzt:MM, 5lzu:MM, 5lzv:MM, 5lzw:MM, 5lzx:MM, 5lzy:MM, 5lzz:MM, 7mdz:MM, 7mq8:LA, 7mq9:LA, 7mqa:LA, 6mtb:MM, 6mtc:MM, 6mtd:MM, 6mte:MM, 7nwg:N2, 7nwh:MM, 7nwi:MM, 7o7y:Al, 7o7z:Al, 7o80:Al, 7o81:Al, 5oa3:M, 6ole:SM, 6olf:SM, 6olg:BM, 6oli:SM, 6olz:BM, 6om0:SM, 6om7:SM, 8oz0:q, 8p03:O, 8p09:O, 8p2k:Al, 6p4g:N, 6p4h:N, 6p5i:N, 6p5j:N, 6p5k:N, 6p5n:N, 8pj1:m, 8pj2:m, 8pj3:m, 8pj4:m, 8pj5:m, 8pj6:m, 8ppk:M, 8ppl:AM, 8q7z:Al, 8q87:Al, 7qgg:SM, 8qoi:SM, 7qp6:m, 7qp7:m, 6qzp:SM, 7r4x:M, 6r5q:RR, 6r6g:RR, 6r6p:RR, 6r7q:RR, 8scb:MM, 6sgc:N1, 7syg:N, 7syh:N, 7syi:N, 7syj:N, 7syk:N, 7syl:N, 7sym:N, 7syn:N, 7syo:N, 7syp:N, 7syq:N, 7syr:N, 7sys:N, 7syt:N, 7syu:N, 7syv:N, 7syw:N, 7syx:N, 5t2c:AM, 8t4s:M, 7toq:AS12, 7tor:AS12, 7tql:O, 4ug0:SM, 4ujc:CM, 4ujd:CM, 4uje:BM, 4v6x:AM, 5vyc:M1, 5vyc:M2, 5vyc:M3, 5vyc:M4, 5vyc:M5, 5vyc:M6, 6w2s:N, 6w2t:N, 7wtt:M, 7wtu:M, 7wtv:M, 7wtw:M, 7wtx:M, 7wtz:M, 7wu0:M, 6xa1:SM, 7xnx:SM, 7xny:SM, 8xsx:SM, 8xsy:SM, 8xsz:SM, 8xxl:SM, 8xxm:SM, 8xxn:SM, 6y0g:SM, 6yal:O, 6yam:O, 6yan:O, 6ybs:m, 8yoo:SM, 8yop:SM, 6z6l:SM, 6z6m:SM, 6z6n:SM, 7zjw:SX, 7zjx:SX, 6zlw:O, 6zm7:SM, 6zme:SM, 6zmi:SM, 6zmo:SM, 6zmt:O, 6zmw:m, 6zn5:O, 6zoj:M, 6zol:M, 6zon:v, 6zp4:v, 6zuo:M, 6zv6:M, 6zvh:M, 6zvj:v, 6zvk:e3, 6zxd:M, 6zxe:M, 6zxf:M, 6zxg:M, 6zxh:M
2 4v6w:AM 119 116 0.6393 0.6555 0.6724 2.51e-52 6xu6:AM, 6xu7:AM, 6xu8:AM
3 4v7e:BM 123 118 0.6148 0.6098 0.6356 4.09e-52 8r57:M
4 7olc:SM 118 113 0.6148 0.6356 0.6637 1.58e-50 7old:SM, 8oo0:SM, 7r81:N2, 7z3n:SM, 7z3o:SM
5 9bh5:AM 117 115 0.5820 0.6068 0.6174 5.76e-44 9cai:AM
6 6zj3:SQ 122 117 0.5574 0.5574 0.5812 1.35e-42
7 8c3a:CZ 119 114 0.5492 0.5630 0.5877 2.88e-42 8c3a:O, 8cq7:O, 8cq7:CZ, 8cqw:O, 8cqw:CZ, 8cre:O, 8cre:CZ, 8oeq:O, 8oeq:CZ, 7pzy:N, 7q08:N, 7q0f:N, 7q0p:N, 7q0r:N
8 7qvp:Rf 78 101 0.6393 1.0000 0.7723 2.95e-41 6y57:Sf
9 8auv:C 117 117 0.5902 0.6154 0.6154 1.71e-39 8b2l:C1
10 8i7j:M 122 117 0.4836 0.4836 0.5043 1.15e-32 6fyx:M, 6fyy:M, 6gsm:M, 6gsn:M, 5it7:M, 5it9:M, 3j80:M, 3j81:M, 3jam:M, 3jap:M, 8rw1:M, 8s8d:M, 8s8e:M, 8s8f:M, 8s8g:M, 8s8h:M, 8s8i:M, 8s8j:M, 6uz7:M
11 8cbj:M 125 117 0.5246 0.5120 0.5470 1.37e-31 7a1g:D, 7b7d:D, 8bqd:D, 8bqx:D, 8cah:D, 8cas:F, 7d5s:SN, 5dat:C2, 5dat:c2, 5dc3:C2, 5dc3:c2, 5dge:C2, 5dge:c2, 5dgf:C2, 5dgf:c2, 5dgv:C2, 5dgv:c2, 6eml:D, 8eub:BM, 8evp:BM, 8evq:BM, 8evr:BM, 8evs:BM, 8evt:BM, 8ewb:BM, 8ewc:BM, 6fai:M, 5fcj:C2, 5fcj:c2, 6gq1:AC, 6gqb:AC, 6gqv:AC, 6hhq:N, 6hhq:c2, 5i4l:C2, 5i4l:c2, 6i7o:D, 6i7o:Db, 3j6x:12, 3j6y:12, 3j77:12, 3j78:12, 5juo:JB, 5jup:JB, 5jus:JB, 5jut:JB, 5juu:JB, 8k2d:SM, 8k82:SM, 6ke6:SN, 6lqp:SN, 6lqu:SN, 5lyb:C2, 5m1j:M2, 5mc6:D, 5mei:c2, 5mei:N, 7mpi:BM, 7mpj:BM, 7n8b:BM, 5ndg:C2, 5ndg:c2, 5ndv:c2, 5ndw:C2, 5ndw:c2, 7nrc:SD, 7nrd:SD, 5obm:C2, 5obm:c2, 5on6:c2, 5on6:N, 7osa:eS12, 6q8y:D, 6rbd:M, 6rbe:M, 7rr5:SM, 6s47:BN, 6snt:M, 6sv4:D, 6sv4:Db, 6sv4:Dc, 6t4q:SM, 6t7i:SM, 6t7t:SM, 6t83:Mb, 6t83:n, 5tbw:N, 5tbw:c2, 6tb3:D, 5tga:C2, 5tga:c2, 5tgm:C2, 5tgm:c2, 6tnu:D, 4u3m:C2, 4u3m:c2, 4u3n:C2, 4u3n:c2, 4u3u:C2, 4u3u:c2, 4u4n:C2, 4u4n:c2, 4u4o:C2, 4u4o:c2, 4u4q:C2, 4u4q:c2, 4u4r:C2, 4u4r:c2, 4u4u:C2, 4u4u:c2, 4u4y:C2, 4u4y:c2, 4u4z:C2, 4u4z:c2, 4u50:C2, 4u50:c2, 4u51:C2, 4u51:c2, 4u52:C2, 4u52:c2, 4u53:C2, 4u53:c2, 4u55:C2, 4u55:c2, 4u56:C2, 4u56:c2, 4u6f:C2, 4u6f:c2, 4uer:U, 4v88:AM, 4v88:CM, 4v8y:AM, 4v8z:AM, 6wdr:M, 6woo:MM, 5wyj:SN, 6y7c:M, 6z6j:SM, 6z6k:SM, 6zce:N, 7zpq:AM, 7zrs:AM, 6zu9:F, 7zuw:AM, 7zux:DM, 6zvi:u, 7zw0:sD
12 7ase:h 121 117 0.3852 0.3884 0.4017 1.01e-29 5opt:i
13 4v8m:AF 121 108 0.3770 0.3802 0.4259 2.20e-27 8ova:AF
14 6az1:Q 115 108 0.3525 0.3739 0.3981 8.40e-25 8ovj:SQ, 8rxh:SQ, 8rxx:SQ
15 5fci:C2 124 114 0.4590 0.4516 0.4912 2.27e-21 5fci:c2, 5lyb:c2
16 5ndv:C2 102 114 0.4344 0.5196 0.4649 1.92e-20
17 4bts:AU 124 104 0.2869 0.2823 0.3365 9.25e-19 4bts:BU, 4bts:CU, 4bts:DU, 4v5o:AU, 4v5o:BU
18 8fvy:M 103 95 0.2787 0.3301 0.3579 9.30e-11 8g4s:M
19 6rm3:SM0 119 108 0.2459 0.2521 0.2778 5.46e-09
20 8p5d:SM0 113 108 0.2541 0.2743 0.2870 7.87e-08 8p60:SM0, 8p60:RM0, 7qca:SM0
21 7qep:C2 118 114 0.2705 0.2797 0.2895 4.01e-07
22 5xyi:M 103 78 0.2131 0.2524 0.3333 1.14e-06
23 8hku:L7A1 123 110 0.2705 0.2683 0.3000 5.94e-06 8hku:L7A2, 8hkv:L7A1, 8hkv:L7A2, 8hkx:SL7A, 8hky:L7A1, 8hky:L7A2, 8hky:SL7A, 8hkz:L7A1, 8hkz:L7A2, 8hkz:SL7A, 8hl1:SL7A, 8hl1:L7A1, 8hl1:L7A2, 8hl2:L7A1, 8hl2:L7A2, 8hl2:SL7A, 8hl3:L7A1, 8hl3:L7A2, 8hl3:SL7A, 8hl4:L7A1, 8hl4:L7A2, 8hl4:SL7A, 8hl5:L7A1, 8hl5:L7A2, 8hl5:SL7A, 8wkp:SL7A, 8wq2:SL7A, 8wq4:SL7A
24 6tmf:b 123 59 0.1721 0.1707 0.3559 5.86e-05
25 8rxh:LG 241 87 0.2131 0.1079 0.2989 7.15e-05 8a3w:G, 8a98:G, 6az3:G, 3jcs:G, 8ovj:G, 8rxx:LG, 5t2a:v
26 4v8m:Bx 240 87 0.2049 0.1042 0.2874 2.52e-04 8ova:Bx, 8ove:Bx, 5t5h:x
27 5gin:C 122 117 0.2459 0.2459 0.2564 3.35e-04 5gin:D, 5gin:L, 5gio:C, 5gio:D, 5gio:L, 5gip:C, 5gip:D, 5gip:M, 5gip:N, 3id5:C, 3id5:G, 5jpq:U, 5jpq:V, 3pla:C, 3pla:D, 3pla:L
28 6q8u:C 122 80 0.2049 0.2049 0.3125 4.56e-04 4bw0:B, 4c4w:C, 4c4w:G, 5fj4:C, 5fj4:G, 5g4u:C, 5g4u:D, 5g4u:G, 5g4u:H, 5g4u:K, 5g4u:L, 5g4v:C, 5g4v:D, 5g4v:G, 5g4v:H, 6hct:C, 6hct:D, 6hct:G, 6q8u:D, 1rlg:A, 1rlg:B
29 5y7m:A 125 56 0.1557 0.1520 0.3393 4.98e-04 4by9:G, 4by9:J, 4by9:D, 4by9:M, 5dcv:A, 5dcv:C, 3hax:D, 3hay:D, 3hjw:C, 2hvy:D, 5jb3:3, 5jbh:3, 3lwo:C, 3lwp:C, 3lwq:C, 3lwr:C, 3lwv:C, 3nmu:G, 3nmu:C, 3nvi:B, 3nvi:D, 3nvk:E, 3nvk:H, 7ozq:B, 7ozq:D, 7ozq:C, 7ozq:A, 6skf:BH, 6skf:BI, 6skg:BH, 6skg:BI, 6sw9:3, 6swc:3, 6swe:3, 6th6:BH, 6th6:BI, 6tph:A, 4v4n:B3, 4v4n:AG, 4v6u:A3, 4v6u:BG, 4v6u:B4, 5xtm:A, 5xtm:C, 5y7m:C, 7zag:3, 7zah:3, 7zai:3, 7zhg:3
30 6zu5:LG0 202 58 0.1230 0.0743 0.2586 0.51
31 2ale:A 132 64 0.1393 0.1288 0.2656 0.86 7ajt:CF, 7ajt:CG, 7aju:CF, 7aju:CG, 7d4i:3G, 7d4i:3H, 7d5s:3G, 7d5s:3H, 7d5t:3G, 7d5t:3H, 7d63:3G, 7d63:3H, 5gan:K, 5gap:K, 3jcm:M, 6ke6:3G, 6ke6:3H, 6lqp:3G, 6lqp:3H, 6lqq:3G, 6lqq:3H, 6lqr:3G, 6lqr:3H, 6lqs:3G, 6lqs:3H, 6lqt:3G, 6lqt:3H, 6lqu:3G, 6lqu:3H, 6lqv:3G, 6lqv:3H, 6nd4:e, 6nd4:f, 5nrl:K, 4nut:A, 7suk:SE, 7suk:SF, 5tzs:f, 5wlc:SE, 5wlc:SF, 5wyj:3G, 5wyj:3H, 5wyk:3G, 5wyk:3H, 6zqa:CF, 6zqb:CF, 6zqb:CG, 6zqc:CF, 6zqc:CG, 6zqd:CF, 6zqd:CG, 6zqe:CF, 6zqe:CG, 5zwm:M, 5zwo:M
32 3loo:B 341 71 0.1557 0.0557 0.2676 1.1 3loo:A, 3loo:C
33 7odx:A 350 90 0.1721 0.0600 0.2333 1.4
34 4j7c:B 217 74 0.1557 0.0876 0.2568 1.8 2hms:A, 2hms:B, 2hms:C, 2hms:D, 2hmt:A, 2hmt:B, 2hmu:A, 2hmu:B, 2hmv:A, 2hmv:B, 2hmw:A, 2hmw:B, 4j7c:A, 4j7c:C, 4j7c:D, 4j7c:E, 4j7c:F, 4j7c:G, 4j7c:H, 4j90:A, 4j90:B, 4j91:A, 4j91:B, 4j91:C, 4j91:D, 8k16:A, 8k16:B, 8k1k:A, 8k1k:B, 8k1s:A, 8k1s:B, 8k1s:C, 8k1s:D, 8k1s:E, 8k1s:F, 8k1s:G, 8k1s:H, 8k1t:A, 8k1t:B, 8k1t:C, 8k1t:D, 8k1t:E, 8k1t:F, 8k1t:G, 8k1t:H, 8k1u:A, 8k1u:B, 8k1u:C, 8k1u:D, 8k1u:E, 8k1u:F, 8k1u:G, 8k1u:H, 1lsu:A, 1lsu:B, 6s2j:A, 6s2j:B, 6s5b:A, 6s5b:B, 6s5b:C, 6s5b:D, 6s5b:E, 6s5b:F, 6s5b:G, 6s5b:H, 6s5c:A, 6s5c:B, 6s5d:A, 6s5d:B, 6s5e:A, 6s5e:B, 6s5e:C, 6s5e:D, 6s5e:E, 6s5e:F, 6s5e:G, 6s5e:H, 6s5g:A, 6s5g:B, 6s5g:C, 6s5g:D, 6s5g:E, 6s5g:F, 6s5g:G, 6s5g:H, 6s5n:A, 6s5n:B, 6s5n:C, 6s5n:D, 6s5n:E, 6s5n:F, 6s5n:G, 6s5n:H, 6s5o:A, 6s5o:B, 6s5o:C, 6s5o:D, 6s5o:E, 6s5o:F, 6s5o:G, 6s5o:H, 6s7r:A, 6s7r:B, 6s7r:C, 6s7r:D, 6s7r:E, 6s7r:F, 6s7r:G, 6s7r:H, 6s7r:I, 6s7r:J, 6s7r:K, 6s7r:L, 6s7r:M, 6s7r:N, 6s7r:O, 6s7r:P, 8xmh:A, 8xmh:B, 8xmh:C, 8xmh:D, 8xmh:E, 8xmh:F, 8xmh:G, 8xmh:H, 8xmi:A, 8xmi:B, 8xmi:C, 8xmi:D, 8xmi:E, 8xmi:F, 8xmi:G, 8xmi:H
35 5oql:V 121 64 0.1230 0.1240 0.2344 3.0 5oql:W, 6rxt:CE, 6rxt:CF, 6rxu:CE, 6rxu:CF, 6rxv:CE, 6rxv:CF, 6rxx:CE, 6rxx:CF, 6rxy:CE, 6rxy:CF, 6rxz:CE, 6rxz:CF
36 6rm3:LG0 195 61 0.1066 0.0667 0.2131 3.2
37 3ewd:A 364 65 0.1230 0.0412 0.2308 3.7 3ewc:A, 2pgf:A, 2pgr:A, 2qvn:A
38 6k0a:I 116 59 0.1393 0.1466 0.2881 3.7 6k0a:J, 6k0b:I, 6k0b:J, 1sds:A, 1sds:C, 1sds:B
39 1qz9:A 404 32 0.0820 0.0248 0.3125 4.2
40 3j79:J 229 59 0.1393 0.0742 0.2881 4.8 3jbn:AJ, 3jbo:AJ, 3jbp:AJ, 8tpu:AJ, 5umd:J
41 7qep:L8 197 58 0.0984 0.0609 0.2069 5.4
42 3jrv:B 144 31 0.0984 0.0833 0.3871 5.8 3jrv:A
43 6eji:A 360 31 0.0984 0.0333 0.3871 7.1 6eji:B, 6ejj:A, 6ejj:B, 6ejk:A, 6ejk:B
44 7xdv:A 283 31 0.0984 0.0424 0.3871 7.5 7xdv:B, 7xdw:A, 7xdw:B, 7xdx:A, 7xdx:B, 7xdy:A, 7xdy:B
45 6ttl:A 479 15 0.0902 0.0230 0.7333 7.9 6ttl:B
46 8fru:G 197 63 0.1393 0.0863 0.2698 8.9 8br8:LI, 8brm:LI, 8bsi:LI, 8bsj:LI, 8btd:LI, 8btr:LI, 7pwg:G, 7pwo:G2
47 6vfu:C 428 45 0.1066 0.0304 0.2889 9.8 6vfu:A, 6vfu:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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