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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEAL
NGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYGTPWTHQDRLD
QIKFYGENKLNTYIYAPKDDPYHREKWREPYPESEMQRMQELINASAENKVDFVFGISPGIDIRFDGDAGEEDFNHLITK
AESLYDMGVRSFAIYWDDIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRAYTRIFAETVDPS
IEVMWTGPGVVTNEIPLSDAQLISGIYNRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKIS
IHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASA
LIEELYGEFARMEEACNNLKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSS
FAVISEKVAQSFIQEALSFDLTLI

The query sequence (length=584) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2v5d:A 722 584 0.9914 0.8019 0.9914 0.0 2cbi:A, 2cbi:B, 2cbj:A, 2cbj:B, 2j1a:A, 2j1e:A, 2j62:A, 2j62:B, 2j7m:A, 7khv:A, 7khv:B, 7khv:C, 7khv:D, 7khv:E, 7khv:F, 5oxd:A, 6rhe:A, 2v5c:A, 2v5c:B, 2vur:A, 2vur:B, 2wb5:A, 2wb5:B, 2x0y:A, 2x0y:B, 2xpk:A, 2xpk:B, 2ydq:A, 2ydr:A, 2yds:A, 4zxl:A
2 7ou8:AAA 714 510 0.3305 0.2703 0.3784 7.70e-110 5abe:A, 5abe:B, 5abf:A, 5abf:B, 5abg:A, 5abg:B, 5abh:A, 5abh:B, 4ais:A, 4ais:B, 4aiu:A, 2chn:A, 2chn:B, 2cho:A, 2cho:B, 5fky:A, 5fky:B, 5fl0:A, 5fl0:B, 5fl1:A, 5fl1:B, 2j47:A, 2j4g:A, 2j4g:B, 2jiw:A, 2jiw:B, 7k41:A, 5mi4:A, 5mi5:A, 5mi6:A, 5mi7:A, 7ou8:BBB, 4ur9:A, 4ur9:B, 2vvn:A, 2vvn:B, 2vvs:A, 2w4x:A, 2w66:A, 2w66:B, 2w67:A, 2w67:B, 2wca:A, 2wzh:A, 2wzi:A, 2wzi:B, 2x0h:A, 2x0h:B, 2xj7:A, 2xj7:B, 2xm1:A, 2xm1:B, 2xm2:A, 2xm2:B
3 5diy:A 463 302 0.1849 0.2333 0.3576 4.80e-53 5diy:B
4 6pv4:C 608 533 0.2671 0.2566 0.2927 4.36e-50 6pv4:A, 6pv4:B, 6pv4:D
5 7yeh:C 344 328 0.1798 0.3052 0.3201 3.78e-48
6 5m7t:A 451 283 0.1695 0.2195 0.3498 4.21e-47 5m7s:A, 5m7s:B, 5m7t:B, 5m7u:A, 5m7u:B, 7ou6:AAA, 7ou6:BBB, 6pm9:A, 6pm9:B, 6pm9:C, 6pm9:D, 5uhl:A, 5uhl:C, 5uho:A, 5uho:C
7 5vvx:C 431 282 0.1661 0.2251 0.3440 1.83e-46 5un8:A, 5un8:C, 5un8:B, 5un8:D, 5un9:A, 5un9:B, 5vvt:A, 5vvt:C, 5vvu:A, 5vvu:C, 5vvv:A, 5vvv:C
8 7khs:A 449 280 0.1438 0.1871 0.3000 3.23e-35 7khs:B, 7khs:D, 2xsb:A
9 7khs:C 427 267 0.1387 0.1897 0.3034 5.64e-35
10 3sur:A 504 206 0.0873 0.1012 0.2476 7.10e-04 3sus:A, 3sut:A, 3suu:A, 3suv:A, 3suw:A
11 2gk1:I 440 96 0.0479 0.0636 0.2917 0.025 2gk1:J, 2gk1:K, 2gk1:L
12 7ezt:B 727 110 0.0497 0.0399 0.2636 0.028
13 8wm7:C 658 65 0.0342 0.0304 0.3077 0.029 8w9m:C
14 5fcz:A 499 85 0.0394 0.0461 0.2706 0.28 4c7f:A, 4c7f:B, 4c7g:A, 1hp5:A, 1jak:A, 1m01:A, 1m03:A, 1m04:A
15 6q63:A 751 67 0.0377 0.0293 0.3284 0.41 6q63:B, 6q63:C
16 7dva:A 523 81 0.0411 0.0459 0.2963 0.44 7dva:B, 7dvb:A, 7dvb:B, 7dvb:C, 7dvb:D
17 7wdt:A 819 86 0.0377 0.0269 0.2558 0.64 7wdu:A, 6z14:JJJ
18 8pxv:B 634 104 0.0479 0.0442 0.2692 0.99 8pxv:C
19 1yfq:A 342 116 0.0599 0.1023 0.3017 2.8 4bl0:A, 4bl0:D
20 7doh:L 218 33 0.0240 0.0642 0.4242 2.8
21 1o7a:A 483 61 0.0325 0.0393 0.3115 3.0 2gk1:N, 2gk1:O, 2gk1:P, 2gk1:R, 2gk1:T, 3lmy:A, 3lmy:B, 1now:A, 1now:B, 1np0:D, 1np0:E, 1np0:F, 1o7a:B, 1o7a:C, 1o7a:D, 1o7a:E, 1o7a:F
22 8hvc:A 602 58 0.0308 0.0299 0.3103 3.2 8hvb:A, 8hvd:A
23 6fsz:MM 978 63 0.0342 0.0204 0.3175 3.7 7ajt:EN, 7aju:EN, 6ft6:MM, 5ooq:A, 5ooq:B, 2xgj:A
24 2xgj:B 777 63 0.0342 0.0257 0.3175 4.4
25 6zns:A 635 72 0.0325 0.0299 0.2639 4.4
26 7rlv:B 219 37 0.0257 0.0685 0.4054 4.8 7rlv:D, 7rlv:F, 7rlw:B, 7rlw:D, 7rlx:B, 7rly:D, 7rly:F, 7rly:B, 7rlz:B, 7rlz:C, 6zvf:L
27 5fm7:B 422 40 0.0205 0.0284 0.3000 5.6
28 5koh:A 483 72 0.0291 0.0352 0.2361 5.8 5koh:C, 5koj:A, 5koj:C
29 8oo7:E 443 40 0.0205 0.0271 0.3000 5.9 8av6:E, 8av6:D, 8av6:F, 6fhs:E, 6fhs:D, 6fhs:F, 6fml:E, 6fml:D, 6fml:F, 8oo7:D, 8oo7:F, 8ooc:D, 8ooc:E, 8ooc:F, 8oop:D, 8oop:E, 8oop:F, 8oor:D, 8oor:E, 8oor:F, 4ww4:B
30 4lc9:A 567 73 0.0394 0.0406 0.3151 6.4
31 1h97:A 147 67 0.0274 0.1088 0.2388 6.7 1h97:B, 1kfr:A
32 3dh9:A 482 95 0.0428 0.0519 0.2632 7.3 3dgh:A, 3dgh:B, 3dh9:B, 2nvk:X
33 6je8:A 469 61 0.0308 0.0384 0.2951 9.4 6jea:A, 6jeb:A
34 5ue8:A 847 111 0.0394 0.0272 0.2072 9.6 5ue8:B, 1y8f:A
35 8fr7:A 1275 49 0.0325 0.0149 0.3878 9.8 8fr7:C, 8fr7:B
36 1aj8:A 371 73 0.0411 0.0647 0.3288 9.8 1aj8:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218