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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VLSAEEIHLIEASVEQFGAPLLLLDCDVIRQQYRALKNALPNVTLHYALKPLPHPVVVRTLLAEGASFDLATTGEVELVA
SEGVPADLTIHTHPIKRDADIRDALAYGCNVFVVDNLNELEKFKAYRDDVELLVRLSFSKKFGCSPEQALVIIETAKEWN
IRIKGLSFHVGSQTTNPNKYVEAIHTCRHVMEQVVERGLPALSTLDIGGGFPVNYTQQVMPIDQFCAPINEALSLLPETV
HVLAEPGRFICAPAVTSVASVMGQAEREGQIWYYLDDGIYGSFSGLMFDDARYPLTTIKGELIPSVLSGPTCDSVDVIAE
NILLPKLNNGDLVIGRTMGAYTSATATDFNFFKRAQTIALNEF

The query sequence (length=363) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2plj:A 376 365 1.0000 0.9654 0.9945 0.0 2plj:B, 2plk:A, 2plk:B
2 5gjo:A 385 373 0.3554 0.3351 0.3458 2.66e-69 5gjn:A, 5gjo:B, 5gjp:A
3 2oo0:A 419 346 0.3416 0.2959 0.3584 2.71e-57 5bwa:A, 7odc:A, 2on3:A, 2on3:B, 2oo0:B, 7s3f:A, 7s3f:B, 7s3g:A, 7s3g:B, 7u6p:A, 7u6p:B, 7u6u:A, 7u6u:B, 4zgy:A
4 1f3t:B 381 348 0.3361 0.3202 0.3506 8.89e-57 1f3t:A, 1f3t:C, 1f3t:D, 1njj:A, 1njj:B, 1njj:C, 1njj:D, 1qu4:A, 1qu4:B, 1qu4:C, 1qu4:D, 1szr:C, 1szr:D, 1szr:A, 1szr:B, 2tod:A, 2tod:B, 2tod:C, 2tod:D
5 2nv9:B 372 329 0.2893 0.2823 0.3191 1.31e-47 2nv9:A, 2nv9:C, 2nv9:D, 2nv9:E, 2nv9:F, 2nv9:G, 2nv9:H, 2nva:A, 2nva:B, 2nva:C, 2nva:D, 2nva:E, 2nva:F, 2nva:G, 2nva:H
6 2yxx:A 385 373 0.2424 0.2286 0.2359 2.93e-24
7 1hkv:A 446 394 0.2590 0.2108 0.2386 1.93e-22 1hkv:B
8 7ru7:A 412 366 0.2176 0.1917 0.2158 1.58e-20 2j66:A
9 3c5q:A 394 367 0.2342 0.2157 0.2316 6.49e-18 2qgh:A
10 5x7m:A 443 386 0.2534 0.2077 0.2383 1.70e-17 5x7m:B, 5x7n:A, 5x7n:B
11 4xg1:B 418 388 0.2617 0.2273 0.2448 3.20e-17 4xg1:C, 4xg1:D
12 4xg1:A 393 376 0.2645 0.2443 0.2553 1.23e-16
13 6knh:C 384 354 0.2369 0.2240 0.2429 2.56e-16 6knh:A, 6knh:B, 6kni:A, 6kni:B, 6kni:C, 6knk:A, 6knk:B, 6knk:C
14 1tuf:A 434 382 0.2452 0.2051 0.2330 5.73e-15 1tuf:B, 1twi:A, 1twi:B, 1twi:C, 1twi:D
15 1knw:A 421 385 0.2617 0.2257 0.2468 8.19e-15 1ko0:A
16 7kh2:D 415 377 0.2011 0.1759 0.1936 3.66e-14 7kh2:A, 7kh2:B, 7kh2:C
17 8d4i:A 462 396 0.2534 0.1991 0.2323 8.06e-10 8d2y:A, 8d4i:C, 8d5d:A, 8d5d:B, 8d5r:A, 8d5r:B, 8d88:A, 8d88:B
18 6n2a:A 422 375 0.2314 0.1991 0.2240 1.94e-07 6n2a:B, 6n2f:B, 6n2f:A
19 3nzp:B 591 246 0.1598 0.0981 0.2358 3.52e-06 3nzp:A
20 3n29:A 371 286 0.1736 0.1698 0.2203 0.004 3n29:B
21 6hiv:CR 314 147 0.1047 0.1210 0.2585 0.010 6hiw:CR, 6hiy:CR, 6hiz:CR, 7pub:CR
22 3nzq:A 628 79 0.0606 0.0350 0.2785 0.039 3nzq:B
23 7aat:A 401 159 0.1047 0.0948 0.2390 2.9 7aat:B, 8aat:A, 8aat:B, 9aat:A, 9aat:B, 1aka:A, 1aka:B, 1akb:A, 1akc:A, 1ama:A, 1ivr:A, 1map:A, 1maq:A, 1oxo:A, 1oxo:B, 1oxp:A, 1tar:A, 1tar:B, 1tas:A, 1tas:B, 1tat:A, 1tat:B
24 4etp:A 379 46 0.0386 0.0369 0.3043 4.5 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
25 2yaj:C 871 61 0.0468 0.0195 0.2787 4.6 2y8n:A, 2yaj:A
26 5fsx:A 233 81 0.0661 0.1030 0.2963 5.0 5fsx:B, 5fsy:A
27 3vyr:B 371 40 0.0413 0.0404 0.3750 7.8 3vys:B, 3vyt:B, 3vyu:B, 2z1d:A, 2z1d:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218