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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGQFVKVSAEREPAN
IDWATDGVEIVLEATGFFASKEKAEQHIHENGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAK
ALQDNFGVKQGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGS
VTELVATLEKDVTVEEVNAAMKAAANDSYGYTEDPIVSSDIVGISYGSLFDATQTKVLTVDGNQLVKVVSWYDNEMSYTS
QLVRTLEYFAKIA

The query sequence (length=333) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5utm:A 345 333 0.9940 0.9594 0.9940 0.0 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
2 5m6d:A 346 333 0.9189 0.8844 0.9189 0.0 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
3 5vmt:B 334 330 0.7087 0.7066 0.7152 1.33e-174 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
4 6fzi:B 332 329 0.7207 0.7229 0.7295 1.46e-171 6fzi:A, 6fzi:C, 6fzi:D
5 3lvf:P 338 334 0.6907 0.6805 0.6886 5.50e-169 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
6 5vmt:E 293 326 0.6607 0.7509 0.6748 1.90e-154
7 5ld5:C 342 339 0.6396 0.6228 0.6283 1.37e-149 5ld5:A, 5ld5:B, 5ld5:D
8 7c5o:O 338 334 0.5946 0.5858 0.5928 6.00e-138 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
9 7www:A 336 337 0.5856 0.5804 0.5786 2.47e-137
10 8hmn:D 340 339 0.5796 0.5676 0.5693 9.31e-134 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
11 7jwk:C 333 333 0.5285 0.5285 0.5285 2.35e-127 7jwk:A, 7jwk:B, 7jwk:D
12 3cmc:O 334 335 0.5495 0.5479 0.5463 1.20e-118 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
13 1hdg:O 332 337 0.5285 0.5301 0.5223 2.38e-118 1hdg:Q
14 3hja:A 334 333 0.5075 0.5060 0.5075 2.13e-116 3hja:B, 3hja:C, 3hja:D
15 8hrq:B 336 336 0.5616 0.5565 0.5565 1.26e-114 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
16 4mvj:B 332 336 0.5105 0.5120 0.5060 2.39e-110 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
17 2ep7:B 339 344 0.5195 0.5103 0.5029 3.78e-110 2ep7:A
18 8br4:A 339 342 0.5315 0.5221 0.5175 2.94e-107 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
19 4p8r:A 331 335 0.4865 0.4894 0.4836 8.81e-107 4p8r:B, 4p8r:C, 4p8r:D
20 4lsm:A 331 334 0.4715 0.4743 0.4701 2.20e-106 4lsm:B
21 3gnq:C 335 333 0.4985 0.4955 0.4985 4.66e-102 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
22 1cer:O 331 332 0.5105 0.5136 0.5120 2.12e-101 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
23 6ghr:B 342 339 0.4985 0.4854 0.4897 6.10e-99 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
24 3cif:A 338 335 0.4685 0.4615 0.4657 3.80e-98 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
25 3doc:A 335 340 0.4925 0.4896 0.4824 6.00e-98 3doc:B, 3doc:C, 3doc:D
26 1obf:O 335 335 0.4835 0.4806 0.4806 1.26e-97 1obf:P
27 7xzg:A 334 337 0.4685 0.4671 0.4629 1.60e-97 7xzg:B, 7xzg:C, 7xzg:D
28 8de5:A 338 339 0.4685 0.4615 0.4602 6.34e-97
29 3l0d:A 332 337 0.4655 0.4669 0.4599 7.33e-97 3l0d:B
30 8oha:B 336 336 0.4625 0.4583 0.4583 1.36e-96 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
31 6ok4:A 334 333 0.4505 0.4491 0.4505 4.26e-96 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
32 1ywg:O 337 328 0.4565 0.4510 0.4634 1.33e-95 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
33 7bew:A 330 334 0.4625 0.4667 0.4611 5.38e-94 7bex:A
34 6px2:A 332 340 0.4895 0.4910 0.4794 7.36e-94 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
35 6nlx:C 335 329 0.4565 0.4537 0.4620 1.03e-93 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
36 2vyn:D 334 334 0.4655 0.4641 0.4641 1.56e-93 2vyv:D
37 6m61:O 336 335 0.4505 0.4464 0.4478 3.01e-93 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
38 3sth:C 340 337 0.4625 0.4529 0.4570 8.24e-93 3sth:A, 3sth:B, 3sth:D
39 6m5x:O 334 335 0.4625 0.4611 0.4597 1.02e-92 6m5x:R, 6m5x:P, 6m5x:Q
40 4k9d:A 338 339 0.4625 0.4556 0.4543 4.50e-92 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
41 3pym:A 332 337 0.4505 0.4518 0.4451 1.02e-90 3pym:B
42 1dss:G 333 336 0.4505 0.4505 0.4464 1.14e-90 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
43 1nbo:O 337 330 0.4474 0.4421 0.4515 1.76e-88 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
44 3gpd:R 334 335 0.4354 0.4341 0.4328 1.97e-88 3gpd:G
45 3b1j:A 338 340 0.4895 0.4822 0.4794 7.36e-88 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
46 3h9e:P 337 332 0.4294 0.4243 0.4307 5.42e-87 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
47 3e5r:O 336 338 0.4354 0.4315 0.4290 2.74e-84 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
48 1a7k:A 358 351 0.4535 0.4218 0.4302 9.72e-84 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
49 6qun:O 334 338 0.4264 0.4251 0.4201 3.86e-81 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
50 3dmt:A 359 353 0.4354 0.4039 0.4108 7.29e-81 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
51 3k2b:A 337 330 0.4565 0.4510 0.4606 7.67e-81 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
52 2i5p:O 309 335 0.4174 0.4498 0.4149 8.19e-80 2i5p:P
53 7q54:C 368 344 0.4685 0.4239 0.4535 2.12e-76 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
54 7zq3:R 348 339 0.4625 0.4425 0.4543 4.05e-76 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
55 9iil:A 341 344 0.3844 0.3754 0.3721 4.91e-72 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
56 2xf8:M 327 341 0.3784 0.3853 0.3695 3.31e-67 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
57 8jb1:A 468 344 0.3814 0.2714 0.3692 1.07e-62 8jb1:B
58 4p0d:A 471 149 0.0991 0.0701 0.2215 0.24
59 1ys4:A 348 67 0.0541 0.0517 0.2687 0.69 1ys4:B
60 3ec7:A 336 46 0.0601 0.0595 0.4348 0.87 3ec7:B, 3ec7:C, 3ec7:D, 3ec7:E, 3ec7:F, 3ec7:G, 3ec7:H
61 8d3x:A 989 75 0.0601 0.0202 0.2667 2.7 8d3u:A, 8d3w:A
62 1cf2:P 336 214 0.1592 0.1577 0.2477 4.4 1cf2:R, 1cf2:O, 1cf2:Q
63 5e3x:A 489 17 0.0330 0.0225 0.6471 5.0
64 5ik7:A 381 71 0.0511 0.0446 0.2394 5.5 1dyk:A, 5ik4:A, 5ik5:A, 5ik7:B, 5ik8:B, 5ik8:A, 1okq:A, 1qu0:A, 1qu0:B, 1qu0:C, 1qu0:D
65 6e9b:D 368 98 0.0721 0.0652 0.2449 6.0
66 3b8e:A 998 75 0.0601 0.0200 0.2667 6.6 3b8e:C, 7d91:A, 7d92:A, 7d93:A, 7d93:C, 7d94:A, 7d94:C, 7ddf:A, 7ddf:C, 7ddh:A, 7ddh:C, 7ddi:A, 7ddi:C, 7ddk:A, 7ddk:C, 7ddl:A, 7ddl:C, 7e1z:A, 7e20:A, 7e21:A, 4hqj:A, 4hqj:C, 4hyt:A, 4hyt:C, 8jbk:A, 8jbk:C, 8jbl:A, 8jbl:C, 8jbm:A, 8jbm:C, 3kdp:A, 3kdp:C, 1mo8:A, 3n23:A, 3n23:C, 7qtv:A, 7qtv:C, 4res:A, 4res:C, 4ret:A, 4ret:C, 3wgu:A, 3wgu:C, 3wgv:A, 3wgv:C, 7wys:A, 7wys:C, 7wyt:A, 7wyt:C, 4xe5:A, 7yzr:A, 7yzr:C, 7z04:A, 7z04:C
67 6ks6:d 524 54 0.0511 0.0324 0.3148 7.0 6ks6:D, 4v81:D, 4v81:L, 4v81:l, 4v8r:AD, 4v8r:Ad, 4v8r:BD, 4v8r:Bd, 4v94:D, 4v94:L, 4v94:d, 4v94:l, 7ylw:D, 7ylw:d, 7ylx:D, 7ylx:d, 7yly:D, 7yly:d
68 7bbm:A 153 44 0.0420 0.0915 0.3182 7.6 3emm:A, 3wjc:A, 3wjc:B
69 4ihc:B 395 117 0.0961 0.0810 0.2735 8.1 4ihc:C, 4ihc:D, 4ihc:E, 4ihc:F, 4ihc:H
70 4a37:B 376 87 0.0661 0.0585 0.2529 8.7 4a37:A, 4a38:A, 4a38:B, 4a39:A, 4a39:B
71 1ecx:B 365 35 0.0450 0.0411 0.4286 8.9 1ecx:A, 1eg5:A, 1eg5:B
72 5eqt:A 249 56 0.0541 0.0723 0.3214 9.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218