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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEI
QRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWME
WQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVA
FAKFEENQKEFERVRVIYKYALDRISKQELFKNYTIFEKKFGDRRGKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAE
AVREVNVPPIQEKRHWKRYIWINYALYEELEAKDPERTRQASLELIPHKKAKMWILYAQFEIRQKARRALGTSIGKCPKK
LFKVYIELELQLREFDREKFLEFGPENCTSWIELETILGDIDRARLAISQPRLDMPEVLWIDFEIEQEETERTRNYRRLL
QRTQHVKVIFAFELSSGKEGSLTKCRQINKTMRNCEEKEERLMLLESFEEEFGTASDKERVDKLMEKVKKRRKVQTDDGS
DAGWEEYF

The query sequence (length=568) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8i0w:J 571 571 1.0000 0.9947 0.9947 0.0 7dvq:J, 8i0u:J, 8i0v:J, 6icz:J, 6id0:J, 6id1:J, 6qdv:S, 7w59:J, 7w5a:J, 7w5b:J, 5xjc:J, 5yzg:J, 5z56:J, 5z57:J, 5z58:J
2 8c6j:S 635 624 0.9824 0.8787 0.8942 0.0 7abi:O, 8ch6:X, 6ff4:O, 8i0r:J, 8i0s:J, 8i0t:J, 5mqf:O, 7qtt:X, 6zym:O
3 8ro0:J 574 586 0.5722 0.5662 0.5546 0.0 8ro1:J
4 3jb9:R 575 249 0.2570 0.2539 0.5863 9.05e-96
5 3jb9:R 575 267 0.1197 0.1183 0.2547 3.66e-06
6 6j6g:d 566 571 0.3398 0.3410 0.3380 5.79e-88 7b9v:S, 6j6h:d, 6j6n:d, 6j6q:d, 5lqw:R
7 7dco:J 554 572 0.3415 0.3502 0.3392 6.79e-80 5y88:I
8 6bk8:T 483 455 0.2923 0.3437 0.3648 2.38e-76 6exn:S, 5lj3:S, 5lj5:S, 5mps:S, 5mq0:S
9 5ylz:I 517 466 0.2887 0.3172 0.3519 4.02e-70
10 5gmk:d 549 237 0.1655 0.1712 0.3966 6.24e-52 5gm6:d, 5wsg:d
11 5gmk:d 549 256 0.1092 0.1129 0.2422 1.06e-07 5gm6:d, 5wsg:d
12 8ro2:I 753 288 0.1356 0.1023 0.2674 3.38e-11
13 8ro2:I 753 228 0.0863 0.0651 0.2149 1.39e-06
14 8ro2:I 753 172 0.0687 0.0518 0.2267 2.27e-05
15 8ro2:I 753 396 0.1549 0.1169 0.2222 0.008
16 8ro2:I 753 130 0.0511 0.0385 0.2231 0.75
17 6qw6:5J 803 249 0.1004 0.0710 0.2289 1.12e-09 8h6e:4G, 8h6j:4G, 8h6k:4G, 8h6l:4G, 8qp8:N, 6qx9:5J, 8y6o:G
18 6qw6:5J 803 527 0.1937 0.1370 0.2087 3.84e-07 8h6e:4G, 8h6j:4G, 8h6k:4G, 8h6l:4G, 8qp8:N, 6qx9:5J, 8y6o:G
19 6qw6:5J 803 255 0.1056 0.0747 0.2353 1.85e-06 8h6e:4G, 8h6j:4G, 8h6k:4G, 8h6l:4G, 8qp8:N, 6qx9:5J, 8y6o:G
20 6qw6:5J 803 95 0.0370 0.0262 0.2211 0.001 8h6e:4G, 8h6j:4G, 8h6k:4G, 8h6l:4G, 8qp8:N, 6qx9:5J, 8y6o:G
21 8r09:N 834 249 0.0968 0.0659 0.2209 1.91e-09 6ahd:N, 5o9z:G, 8q7n:N, 8qo9:N, 8qpe:N, 8qzs:N, 8r0b:N, 8rc0:E, 8rm5:N
22 8r09:N 834 529 0.1972 0.1343 0.2117 3.56e-08 6ahd:N, 5o9z:G, 8q7n:N, 8qo9:N, 8qpe:N, 8qzs:N, 8r0b:N, 8rc0:E, 8rm5:N
23 8r09:N 834 255 0.1056 0.0719 0.2353 1.34e-06 6ahd:N, 5o9z:G, 8q7n:N, 8qo9:N, 8qpe:N, 8qzs:N, 8r0b:N, 8rc0:E, 8rm5:N
24 8r09:N 834 103 0.0405 0.0276 0.2233 0.001 6ahd:N, 5o9z:G, 8q7n:N, 8qo9:N, 8qpe:N, 8qzs:N, 8r0b:N, 8rc0:E, 8rm5:N
25 7suk:LP 359 173 0.0651 0.1031 0.2139 1.63e-04 5wlc:LP
26 7d4i:B6 377 162 0.0616 0.0928 0.2160 1.88e-04 7ajt:UF, 7d5s:B6, 7d5t:B6, 7d63:B6, 6ke6:B6, 6lqp:B6, 6lqq:B6, 6lqr:B6, 6lqs:B6, 6lqt:B6, 6lqu:B6, 6lqv:B6, 6zqa:UF, 6zqb:UF, 6zqc:UF
27 6rxy:Cz 275 215 0.0792 0.1636 0.2093 5.42e-04 6rxz:Cz
28 6rxy:Cz 275 174 0.0757 0.1564 0.2471 0.004 6rxz:Cz
29 5oql:E 331 90 0.0423 0.0725 0.2667 0.015 6rxt:UF, 6rxu:UF, 6rxv:UF, 6rxy:UF, 6rxz:UF
30 5oql:E 331 164 0.0669 0.1148 0.2317 0.032 6rxt:UF, 6rxu:UF, 6rxv:UF, 6rxy:UF, 6rxz:UF
31 7zy4:B 306 142 0.0651 0.1209 0.2606 0.027 7zy4:A
32 7zy4:B 306 307 0.1144 0.2124 0.2117 0.078 7zy4:A
33 7zy4:B 306 184 0.0704 0.1307 0.2174 1.5 7zy4:A
34 5nrl:J 800 216 0.0810 0.0575 0.2130 0.038 5gan:J, 5gap:J
35 5nrl:J 800 146 0.0563 0.0400 0.2192 0.95 5gan:J, 5gap:J
36 5nrl:J 800 88 0.0352 0.0250 0.2273 4.3 5gan:J, 5gap:J
37 8qoz:N 457 222 0.0792 0.0985 0.2027 0.21 8qpa:N, 8qpb:N
38 7d5s:RD 265 182 0.0775 0.1660 0.2418 0.41 6lqu:RD, 7suk:NJ, 5wlc:NJ
39 7d5s:RD 265 82 0.0405 0.0868 0.2805 0.55 6lqu:RD, 7suk:NJ, 5wlc:NJ
40 7d5s:RD 265 234 0.0845 0.1811 0.2051 0.80 6lqu:RD, 7suk:NJ, 5wlc:NJ
41 7mq8:LP 567 126 0.0493 0.0494 0.2222 1.4 7mq9:LP, 7mqa:LP
42 7mq8:LP 567 103 0.0405 0.0406 0.2233 4.7 7mq9:LP, 7mqa:LP
43 7mq8:LP 567 293 0.1144 0.1146 0.2218 8.3 7mq9:LP, 7mqa:LP
44 4hr6:C 264 104 0.0440 0.0947 0.2404 2.7 5y97:C
45 5fub:A 337 59 0.0282 0.0475 0.2712 3.1 5g02:A
46 7pua:F9 540 237 0.1004 0.1056 0.2405 4.6 7pub:F9, 6sga:F9, 6sgb:F9
47 6n7p:D 544 59 0.0246 0.0257 0.2373 4.7 6g90:E, 6n7r:D, 6n7x:D, 7oqc:E, 7oqe:E, 8w2o:D, 5zwn:T
48 5zwn:U 583 141 0.0546 0.0532 0.2199 5.8 7oqc:D, 7oqe:D
49 3jcm:G 734 48 0.0264 0.0204 0.3125 6.3 5zwm:N, 5zwo:N
50 3ruq:A 516 88 0.0370 0.0407 0.2386 7.7 3kfb:A, 3kfb:B, 3kfb:C, 3kfb:D, 3kfb:E, 3kfb:F, 3kfb:G, 3kfb:H, 7rak:U, 7rak:A, 7rak:B, 7rak:C, 7rak:D, 7rak:E, 7rak:F, 7rak:G, 7rak:H, 7rak:I, 7rak:J, 7rak:K, 7rak:L, 7rak:M, 7rak:N, 7rak:O, 3ruq:B, 3ruq:C, 3ruq:D, 3rus:A, 3rus:B, 3rus:C, 3rus:D, 3ruv:A, 3ruv:B, 3ruv:C, 3ruv:D, 3ruw:A, 3ruw:B, 3ruw:C, 3ruw:D
51 7miz:x 143 82 0.0387 0.1538 0.2683 9.6 7miz:k, 7tnq:w, 7tnq:x
52 8im8:A 557 28 0.0229 0.0233 0.4643 9.9 8im8:B, 8im8:C, 8im8:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218