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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VKKVDDVTGEKVREAFEQFLEDFSVGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPFLQKG
LRRVVRKYAPELLEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQ
SFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIV
VPDVTQLGLPGVKPSSNSGVTGLRSLGVRDLTYKISFLACHVISIGRDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRS
IAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAV
VRDEDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSL
RGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKE
LRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRV

The query sequence (length=619) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7v3u:6 646 642 0.9887 0.9474 0.9533 0.0 7qhs:6, 7v3u:F, 7v3v:6, 7v3v:F, 7w8g:6, 7w8g:F, 7z13:6, 7z13:e
2 5v8f:6 692 624 0.9661 0.8642 0.9583 0.0 8b9a:6, 8b9b:6, 8b9c:6, 6eyc:6, 3ja8:6, 8kg6:6, 8kg8:6, 8kg9:6, 7p30:6, 7p30:E, 7p5z:6, 7p5z:E, 8p5e:6, 8p62:6, 8p63:6, 7pmk:6, 7pmn:6, 6ptn:m, 6ptn:6, 6pto:l, 6pto:6, 7pt6:6, 7pt6:F, 7pt7:6, 7pt7:F, 6rqc:6, 6skl:6, 6sko:6, 6u0m:6, 5u8s:6, 8w7m:6, 8xgc:6
3 5u8t:6 661 631 0.9354 0.8759 0.9176 0.0 6wgi:6
4 7w1y:6 716 646 0.5363 0.4637 0.5139 0.0 7w1y:E
5 6xtx:6 679 633 0.5186 0.4728 0.5071 0.0 8b9d:6, 7pfo:6, 7plo:6, 6xty:6
6 6rax:6 628 636 0.5057 0.4984 0.4921 0.0 6ray:6
7 8ouw:6 707 635 0.4943 0.4328 0.4819 0.0
8 6raw:6 601 630 0.4992 0.5141 0.4905 0.0 6raz:6
9 8q6p:6 395 329 0.3183 0.4987 0.5988 2.68e-142
10 4r7y:A 591 627 0.3861 0.4044 0.3812 2.02e-125 4r7y:B, 4r7z:A, 4r7z:B, 4r7z:C, 4r7z:D, 4r7z:E, 4r7z:F, 4r7z:G, 4r7z:H, 4r7z:I, 4r7z:P, 4r7z:J, 4r7z:K, 4r7z:L, 4r7z:M, 4r7z:N, 4r7z:O
11 6xtx:7 598 623 0.3716 0.3846 0.3692 8.04e-122 6xty:7
12 4fdg:B 592 619 0.3764 0.3936 0.3764 3.88e-121 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
13 8x7u:D 654 578 0.3619 0.3425 0.3875 2.12e-120 8x7u:E, 8x7u:C, 8x7u:B, 8x7u:F, 8x7u:A
14 7w1y:F 643 544 0.3586 0.3453 0.4081 1.85e-118 7w1y:7
15 7plo:7 607 644 0.3748 0.3822 0.3602 3.04e-114 7pfo:7
16 8ouw:4 619 632 0.3700 0.3700 0.3623 1.14e-112
17 6rax:2 605 611 0.3393 0.3471 0.3437 3.07e-112 6raw:2, 6ray:2
18 8b9d:7 576 632 0.3667 0.3941 0.3592 8.97e-112
19 5v8f:4 741 562 0.3425 0.2861 0.3772 1.50e-110 5bk4:C, 5bk4:4, 6eyc:4, 6f0l:C, 3ja8:4, 7p30:4, 7p30:C, 7p5z:C, 7p5z:4, 7pt6:4, 7pt6:D, 7pt7:4, 7pt7:D, 6rqc:4, 7v3u:4, 7v3u:D, 7v3v:4, 7v3v:D, 7w8g:4, 7w8g:D
20 7v3u:7 699 517 0.3279 0.2904 0.3926 1.68e-110 5bk4:F, 5bk4:7, 6eyc:7, 3ja8:7, 7p30:7, 7p30:F, 7p5z:7, 7p5z:F, 7v3u:G, 7v3v:7, 7v3v:G, 7w8g:7, 7w8g:G
21 5v8f:7 725 517 0.3231 0.2759 0.3868 6.87e-110 8b9a:7, 8b9b:7, 8b9c:7, 3jc6:7, 3jc7:7, 8kg6:7, 8kg8:7, 8p5e:7, 8p62:7, 8p63:7, 7pt6:7, 7pt6:G, 7pt7:7, 7pt7:G, 7qhs:7, 6rqc:7, 6sko:7, 8w7m:7, 7z13:7, 7z13:f
22 6rax:4 626 569 0.3393 0.3355 0.3691 1.08e-109 6raw:4, 6ray:4, 6raz:4
23 7pt6:2 629 608 0.3409 0.3355 0.3470 1.10e-109 5bk4:2, 5bk4:A, 6eyc:2, 6f0l:A, 6f0l:2, 3ja8:2, 7p30:2, 7p30:A, 7p5z:2, 7p5z:A, 7pt6:B, 7pt7:2, 7pt7:B, 6rqc:2, 6sko:2, 5u8s:2, 7v3u:2, 7v3u:B, 7v3v:2, 7v3v:B, 5v8f:2, 8w7m:2, 7w8g:2, 7w8g:B
24 7w1y:2 706 621 0.3360 0.2946 0.3349 1.54e-108 7pfo:2, 7plo:2, 8q6o:A, 8q6o:2, 8q6p:2, 7w1y:A, 6xtx:2, 6xty:2
25 7w1y:4 653 529 0.3312 0.3139 0.3875 1.97e-108 7w1y:C, 6xtx:4, 6xty:4
26 8kg8:4 697 531 0.3279 0.2912 0.3823 6.03e-108 8b9a:4, 8b9b:4, 8b9c:4, 8kg6:4, 8p5e:4, 8p62:4, 8p63:4, 7pmk:4, 7pmn:4, 7qhs:4, 6sko:4, 8w7m:4, 7z13:4, 7z13:c
27 6raz:7 601 639 0.3764 0.3877 0.3646 5.17e-107 6ray:7
28 8b9d:4 677 621 0.3506 0.3205 0.3494 1.21e-105 7pfo:4, 7plo:4
29 6rax:7 632 647 0.3764 0.3687 0.3601 1.26e-105 6raw:7
30 8ouw:7 632 552 0.3247 0.3180 0.3641 2.07e-105
31 6skl:4 679 527 0.3215 0.2931 0.3776 3.47e-103 8kg9:4, 8xgc:4
32 8kg9:7 636 512 0.3069 0.2987 0.3711 1.37e-102 7pmk:7, 7pmn:7, 6skl:7, 8xgc:7
33 6xtx:3 608 615 0.3376 0.3438 0.3398 2.22e-102
34 8xgc:2 778 627 0.3360 0.2674 0.3317 2.67e-102 8kg6:2, 8kg8:2, 8kg9:2, 8p5e:2, 8p62:2, 8p63:2, 7pmk:2, 7pmn:2, 6ptn:i, 6ptn:2, 6pto:h, 6pto:2, 7qhs:2, 6skl:2, 6u0m:2, 7z13:2, 7z13:a
35 5u8t:2 583 612 0.3247 0.3448 0.3284 4.37e-100
36 8b9d:2 576 638 0.3312 0.3559 0.3213 7.17e-99
37 8w7m:3 619 522 0.3134 0.3134 0.3716 9.27e-99 8b9a:3, 8b9b:3, 8b9c:3, 7pmk:3, 6skl:3, 8xgc:3
38 7pmn:5 660 641 0.3409 0.3197 0.3292 1.50e-98
39 8ouw:3 619 528 0.3037 0.3037 0.3561 3.80e-98
40 5v8f:3 654 634 0.3619 0.3425 0.3533 3.96e-98 5bk4:B, 5bk4:3, 6eyc:3, 6f0l:3, 6f0l:B, 3ja8:3, 7p30:3, 7p30:B, 7p5z:3, 7p5z:B, 6ptn:j, 6ptn:3, 6pto:i, 6pto:3, 6rqc:3, 6sko:3, 6u0m:3, 5u8s:3, 5u8t:3
41 6raz:2 559 610 0.3279 0.3631 0.3328 7.41e-98
42 8p5e:5 695 621 0.3247 0.2892 0.3237 1.26e-97 6eyc:5, 6f0l:D, 6f0l:5, 3ja8:5, 8kg6:5, 8kg8:5, 8kg9:5, 7p30:5, 7p30:D, 7p5z:5, 7p5z:D, 8p62:5, 8p63:5, 7pmk:5, 6ptn:l, 6ptn:5, 6pto:k, 6pto:5, 7pt6:5, 7pt6:E, 7pt7:5, 7pt7:E, 7qhs:5, 6rqc:5, 6skl:5, 6u0m:5, 5u8s:5, 5u8t:5, 7v3u:5, 7v3u:E, 7v3v:5, 7v3v:E, 7w8g:5, 7w8g:E, 8xgc:5, 7z13:5, 7z13:d
43 7w1y:B 651 666 0.3473 0.3303 0.3228 1.44e-96 7w1y:3
44 7pt7:C 633 659 0.3570 0.3491 0.3354 3.71e-96
45 6hv9:3 558 510 0.3150 0.3495 0.3824 4.55e-96
46 8p5e:3 649 681 0.3603 0.3436 0.3275 5.47e-96 8kg6:3, 8kg8:3, 8kg9:3, 8p62:3, 8p63:3, 7pt6:3, 7pt6:C, 7pt7:3, 7qhs:3, 7v3u:3, 7v3u:C, 7v3v:3, 7v3v:C, 7w8g:3, 7w8g:C, 7z13:3, 7z13:b
47 7plo:3 628 655 0.3441 0.3392 0.3252 1.45e-95 7pfo:3
48 7w1y:5 710 634 0.3344 0.2915 0.3265 3.10e-94 7plo:5, 7w1y:D
49 8ouw:2 701 636 0.3312 0.2924 0.3223 1.16e-93
50 5bk4:D 661 643 0.3296 0.3086 0.3173 2.03e-93 5bk4:5
51 8b9d:3 569 622 0.3360 0.3656 0.3344 5.65e-93
52 6wgi:3 637 636 0.3473 0.3375 0.3381 7.82e-93
53 7pfo:5 605 633 0.3263 0.3339 0.3191 2.14e-92 8b9d:5
54 6ray:3 600 521 0.3021 0.3117 0.3589 8.72e-90 6raw:3, 6raz:3
55 8s91:A 602 564 0.3166 0.3256 0.3475 1.27e-88 7dp3:A, 8s91:B, 8s91:C, 8s94:A, 8s94:C, 8s94:B
56 6rax:3 625 539 0.3021 0.2992 0.3469 1.71e-87
57 6rax:5 620 638 0.3312 0.3306 0.3213 3.17e-87 6ray:5, 6raz:5
58 8b9a:5 533 590 0.3069 0.3565 0.3220 3.62e-85 8b9b:5, 8b9c:5, 6sko:5
59 6hv9:5 628 633 0.3231 0.3185 0.3160 6.05e-85
60 6xtx:5 577 628 0.3183 0.3414 0.3137 4.41e-83 6xty:5
61 7wi7:A 565 560 0.3102 0.3398 0.3429 7.68e-83
62 6raw:5 576 629 0.3231 0.3472 0.3180 4.20e-82
63 6hv9:2 549 600 0.3150 0.3552 0.3250 1.94e-81
64 8s91:D 621 504 0.2811 0.2802 0.3452 2.68e-81 7dpd:A, 7dpd:B, 8s91:E, 8s91:F, 8s94:D, 8s94:F, 8s94:E
65 8q6p:3 370 338 0.2246 0.3757 0.4112 1.40e-80
66 8b9a:2 568 626 0.3037 0.3310 0.3003 5.57e-77 8b9b:2, 8b9c:2
67 7wi7:B 566 493 0.2714 0.2968 0.3408 1.69e-75
68 8q6p:5 321 334 0.2229 0.4299 0.4132 6.84e-75
69 8ouw:5 541 625 0.2973 0.3401 0.2944 2.15e-69
70 8w7m:5 529 590 0.2763 0.3233 0.2898 6.16e-69
71 8q6p:7 298 329 0.2246 0.4664 0.4225 4.32e-66
72 8q6o:E 249 279 0.1729 0.4297 0.3835 1.73e-58 8q6o:6
73 8q6o:F 275 158 0.0905 0.2036 0.3544 1.68e-25 8q6o:7
74 4pof:A 255 239 0.1163 0.2824 0.3013 2.78e-21 5iy0:A, 5iy0:B, 5iy0:C, 5iy0:D, 5iy0:E, 5iy0:F, 4pof:B, 4pof:C, 4pof:D, 4pof:E, 4pof:F, 4pog:A, 4pog:E, 4pog:F, 4pog:K, 4pog:L, 4pog:G, 4pog:H, 4pog:I, 4pog:J, 4pog:B, 4pog:C, 4pog:D, 4ywl:A, 4ywl:B, 4ywl:C, 4ywl:D, 4ywl:E, 4ywl:F, 4ywl:G, 4ywl:H, 4ywl:I, 4ywl:J, 4ywm:A, 4ywm:B, 4ywm:C, 4ywm:D, 4ywm:E, 4ywm:F, 4ywm:G, 4ywm:H, 4ywm:I, 4ywm:J
75 8q6o:C 258 238 0.1034 0.2481 0.2689 1.09e-19 8q6o:4
76 1ltl:E 242 239 0.1163 0.2975 0.3013 6.15e-18 1ltl:A, 1ltl:B, 1ltl:C, 1ltl:D, 1ltl:F
77 4me3:A 246 233 0.0937 0.2358 0.2489 2.15e-15
78 8q6o:D 256 236 0.0808 0.1953 0.2119 9.10e-10 8q6o:5
79 8beg:A 650 91 0.0388 0.0369 0.2637 0.014 8beg:B
80 4qht:C 248 183 0.0630 0.1573 0.2131 0.55 6luf:A, 6luf:B, 6luf:C, 6luf:D, 6luf:E, 6luf:F, 6luf:G, 4qht:A, 4qht:B, 4qht:D, 4qht:E, 4qht:F, 4qht:G
81 2r65:A 249 115 0.0549 0.1365 0.2957 0.82 2r65:B, 2r65:C, 2r65:D, 2r65:E
82 8opr:A 651 53 0.0226 0.0215 0.2642 1.4
83 6eom:A 524 127 0.0420 0.0496 0.2047 3.9
84 3jtm:A 351 30 0.0226 0.0399 0.4667 5.0 3n7u:A, 3n7u:B, 3n7u:C, 3n7u:D, 3n7u:E, 3n7u:F, 3n7u:G, 3n7u:H, 3n7u:I, 3n7u:J, 3n7u:K, 3n7u:L
85 6g99:B 41 11 0.0129 0.1951 0.7273 5.2
86 6qpa:A 310 41 0.0226 0.0452 0.3415 5.4 6qpa:B, 6qpa:C, 6qpa:D, 6qpa:E, 6qpa:F, 6qpa:G, 6qpa:H, 6qpa:I, 6qpa:J, 6qpa:K, 6qpa:L, 6qpa:M, 6qpa:N, 6qpa:O, 6qpa:P, 6qpa:Q, 6qpa:R, 6qpa:T, 6qpa:U, 6qpa:V, 6qpa:W, 6qpa:Y, 6qpa:Z
87 6v59:A 419 38 0.0226 0.0334 0.3684 5.4 6nx0:A, 6v59:B
88 1ny5:B 385 102 0.0420 0.0675 0.2549 9.1 4bs1:A, 4bs1:B, 4bt0:A, 4bt0:B, 4bt1:A, 4bt1:B, 4ly6:A, 4ly6:B, 4ly6:C, 4ly6:D, 4ly6:E, 4ly6:G, 4ly6:H, 4ly6:I, 4ly6:J, 4ly6:K, 4ly6:L, 4ly6:M, 4ly6:N, 4ly6:O, 4ly6:P, 4ly6:Q, 4ly6:R, 4ly6:S, 4ly6:T, 4ly6:U, 4ly6:V, 4ly6:W, 4ly6:X, 4lzz:A, 4lzz:B, 4lzz:C, 4lzz:D, 4lzz:E, 4lzz:F, 4lzz:G, 4lzz:H, 4lzz:I, 4lzz:J, 4lzz:K, 4lzz:L, 4lzz:M, 4lzz:N, 4lzz:O, 4lzz:P, 4lzz:Q, 4lzz:R, 4lzz:S, 4lzz:T, 4lzz:U, 4lzz:V, 4lzz:W, 4lzz:X, 3m0e:A, 3m0e:B, 3m0e:C, 3m0e:D, 3m0e:E, 3m0e:F, 3m0e:G, 1ny5:A, 1ny6:A, 1ny6:B, 1ny6:C, 1ny6:D, 1ny6:E, 1ny6:F, 1ny6:G, 1ny6:H, 1ny6:I, 1ny6:J, 1ny6:K, 1ny6:L, 1ny6:M, 1ny6:N, 1zy2:A
89 5nrl:J 800 39 0.0210 0.0163 0.3333 9.2 5gan:J, 5gap:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218