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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMR
VYFEKPRTTVGWKGLINDPHLDGTFDINFGLSQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVH
RELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQ
LRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEE
LLALLAGANKKRMARA

The query sequence (length=336) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5dcb:C 348 335 0.9940 0.9598 0.9970 0.0 5cz0:A, 5cz0:B, 5cz0:C, 5cz0:D, 5czs:A, 5czs:B, 5czs:C, 5czs:D, 5czt:A, 5czt:B, 5czt:C, 5czt:D, 5d02:A, 5d02:B, 5d02:C, 5d02:D, 5d03:A, 5d03:B, 5d03:C, 5d03:D, 5d04:C, 5d04:D, 5d05:A, 5d05:B, 5d05:C, 5d05:D, 5d09:A, 5d09:B, 5d09:C, 5d09:D, 5dcb:A, 5dcb:B, 5dcb:D, 5dcd:A, 5dcd:B, 5dcd:C, 5dcd:D, 5dce:A, 5dce:B, 5dce:C, 5dce:D, 4hsn:A, 4hsn:B, 4hsn:C, 4hsn:D, 4hso:A, 4hso:B, 4hso:C, 4hso:D, 4ixx:A, 4ixx:B, 4ixx:C, 4ixx:D, 4uc5:A, 4uc5:B, 4uc5:C, 4uc5:D, 4ucg:A, 4ucg:B, 4ucg:C, 4ucg:D, 4uma:A, 4uma:B, 4uma:C, 4uma:D, 4umb:A, 4umb:B, 4umb:C, 4umb:D, 4umc:A, 4umc:B, 4umc:C, 4umc:D
2 1kfl:A 350 336 0.6518 0.6257 0.6518 7.80e-158 5cks:A, 5cks:B, 5cks:C, 5cks:D, 8e0s:A, 8e0s:B, 8e0s:C, 8e0s:D, 8e0t:B, 8e0t:C, 8e0v:A, 8e0v:B, 8e0v:C, 8e0v:D, 8e0x:A, 8e0x:B, 8e0x:C, 8e0x:D, 8e0y:C, 1gg1:A, 1gg1:B, 1gg1:C, 1gg1:D, 1kfl:B, 1kfl:C, 1kfl:D, 1kfl:E, 1kfl:F, 1kfl:G, 1kfl:H, 1n8f:A, 1n8f:B, 1n8f:C, 1n8f:D, 1qr7:A, 1qr7:B, 1qr7:C, 1qr7:D, 7rud:B, 7rud:C, 7rud:D, 7rue:A, 7rue:B, 7rue:C, 7rue:D
3 3tqk:A 341 335 0.5268 0.5191 0.5284 2.78e-134
4 7reu:B 358 340 0.5268 0.4944 0.5206 2.03e-123 7reu:A
5 6agm:A 334 309 0.5030 0.5060 0.5469 4.60e-123 6agm:B, 6agm:C, 6agm:D
6 1of6:A 350 336 0.5417 0.5200 0.5417 4.22e-120 1hfb:A, 1hfb:B, 1hfb:C, 1hfb:D, 1hfb:E, 1hfb:F, 1hfb:G, 1hfb:H, 1oab:A, 1oab:B, 1of6:B, 1of6:C, 1of6:D, 1of6:E, 1of6:F, 1of6:G, 1of6:H, 1of8:A, 1of8:B, 1ofa:B, 1ofa:A, 1ofb:A, 1ofb:B, 1ofo:A, 1ofo:B, 1ofq:A, 1ofq:B, 1ofq:C, 1ofq:D, 1ofr:A, 1ofr:H, 1ofr:C, 1ofr:D, 1ofr:E, 1ofr:F, 1ofr:G, 1ofr:B, 1og0:A, 1og0:B, 1og0:C, 1og0:D, 1og0:E, 1og0:F, 1og0:G, 1og0:H
7 6dcf:D 1176 45 0.0536 0.0153 0.4000 0.84 6vvv:D
8 6vvt:D 1200 45 0.0536 0.0150 0.4000 0.86
9 6z11:D 1254 45 0.0536 0.0144 0.4000 0.87 6ccv:D, 6eyd:D, 6f6w:D, 5tw1:D, 5vi5:D, 5vi8:D, 6vvs:D
10 6cce:D 1195 45 0.0536 0.0151 0.4000 0.87
11 1j0a:A 325 80 0.0625 0.0646 0.2625 1.0 1j0a:B, 1j0a:C, 1j0b:A, 1j0b:B, 1j0b:C, 1j0b:D, 1j0b:E, 1j0b:F, 1j0b:G, 1j0b:H, 1j0b:I, 1j0b:J, 1j0b:K, 1j0b:L, 1j0b:M, 1j0b:N, 1j0b:O, 1j0b:P, 1j0b:Q, 1j0b:R, 1j0b:S, 1j0b:T, 1j0b:U, 1j0b:V, 1j0b:W, 1j0b:X
12 8i23:D 1154 45 0.0476 0.0139 0.3556 1.5 8i24:D
13 8duj:A 3823 65 0.0536 0.0047 0.2769 1.7
14 2a21:A 263 46 0.0417 0.0532 0.3043 1.8 2a21:B, 2a2i:A, 2a2i:B, 3e0i:A, 3e0i:B, 3e12:A, 3e12:B, 2ef9:A, 2ef9:B, 1fwn:A, 1fwn:B, 1fws:A, 1fws:B, 1fwt:A, 1fwt:B, 1fww:A, 1fww:B, 1fx6:A, 1fx6:B, 1fxp:A, 1fxp:B, 1fxq:A, 1fxq:B, 1fy6:A, 1fy6:B, 1jcx:A, 1jcx:B, 1jcy:A, 1jcy:B, 1lrn:A, 1lrn:B, 1lro:A, 1lro:B, 1lrq:A, 1lrq:B, 2nwr:A, 2nwr:B, 2nws:A, 2nws:B, 2nx1:A, 2nx1:B, 2nx3:A, 2nx3:B, 2nx3:C, 2nx3:D, 2nx3:E, 2nx3:F, 2nx3:G, 2nx3:H, 2nx3:I, 2nx3:J, 2nx3:K, 2nx3:L, 2nxg:A, 2nxg:B, 2nxh:A, 2nxh:B, 2nxh:C, 2nxh:D, 2nxh:E, 2nxh:F, 2nxh:G, 2nxh:H, 2nxh:I, 2nxh:J, 2nxh:K, 2nxh:L, 2nxi:A, 2nxi:B, 2nxi:C, 2nxi:D, 2nxi:E, 2nxi:F, 2nxi:G, 2nxi:H, 2nxi:I, 2nxi:J, 2nxi:K, 2nxi:L, 1pck:A, 1pck:B, 1pcw:A, 1pcw:B, 1pe1:A, 1pe1:B, 1t8x:A, 1t8x:B, 1t96:A, 1t96:B, 1zha:A, 1zha:B, 1zji:A, 1zji:B
15 7ob9:M 388 89 0.0714 0.0619 0.2697 2.0
16 4pxq:A 516 73 0.0625 0.0407 0.2877 5.0 4pxq:B
17 8weq:C 394 70 0.0744 0.0635 0.3571 6.1 8weq:A, 8weq:B
18 8ej3:D 1281 35 0.0446 0.0117 0.4286 9.2 6bzo:D, 6c04:D, 6c05:D, 6c06:D, 6dv9:D, 6dvb:D, 6dvc:D, 6dvd:D, 6dve:D, 8e74:D, 8e79:D, 8e82:D, 8e8m:D, 8e95:D, 6edt:D, 6ee8:D, 6eec:D, 8ehq:D, 8eoe:D, 8eof:D, 8eos:D, 8eot:D, 8exy:D, 6fbv:D, 8hih:D, 6jcx:D, 6jcy:D, 7kif:D, 7kim:D, 7kin:D, 6kon:D, 6koo:D, 6kop:D, 6koq:D, 6m7j:D, 7p5x:AD, 7pp4:d, 8q3i:D, 7q4u:D, 7q4u:J, 7q4u:P, 7q4u:W, 7q4u:CA, 7q4u:IA, 7q4u:OA, 7q4u:UA, 7q59:D, 7q59:d, 7rwi:D, 6tye:D, 6tyf:D, 6tyg:D, 7u22:D, 5uh5:D, 5uh6:D, 5uh8:D, 5uh9:D, 5uha:D, 5uhb:D, 5uhc:D, 5uhd:D, 5uhe:D, 5uhf:D, 5uhg:D, 6vvx:D, 6vvy:D, 6vvz:D, 6vw0:D, 6yxu:D, 6yys:D, 7z8q:d, 7zf2:D, 5zx2:D, 5zx3:D
19 7f75:D 1142 45 0.0476 0.0140 0.3556 9.7 7ckq:D
20 6wvk:D 1184 45 0.0476 0.0135 0.3556 9.8 6wvj:D
21 6zca:Y 1127 45 0.0476 0.0142 0.3556 9.9 6zfb:Y, 6zfb:y

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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