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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMIDEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYY
PVSVDAKHGKNLKKVEAAAIKATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIGNKPGVTKQQQWIKVG
NALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQNDLARLKSHYNIEVPEDAEIIAWFDAIGK
KRGLIRRGNEIDYEAVIELIIYDIRNAKIGNYCFDIFKDMTEELANDAN

The query sequence (length=289) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6g0z:A 290 289 1.0000 0.9966 1.0000 0.0 6g0z:B, 6g12:A, 6g12:B, 6g14:B, 6g14:A, 6g15:A, 6g15:B
2 1puj:A 261 269 0.4879 0.5402 0.5242 4.09e-96 6ppk:W
3 7pd3:z 311 235 0.2734 0.2540 0.3362 9.76e-37 8pk0:z, 8qsj:z
4 7o9k:C 255 217 0.2388 0.2706 0.3180 1.50e-28 7o9m:C
5 3cnl:A 233 266 0.2595 0.3219 0.2820 6.30e-27 3cnn:A, 3cno:A
6 6yxy:EM 330 297 0.2907 0.2545 0.2828 4.25e-25
7 6yxx:EM 308 200 0.2215 0.2078 0.3200 5.66e-24
8 7am2:BT 300 230 0.2249 0.2167 0.2826 8.90e-24
9 8fkt:NB 387 279 0.2422 0.1809 0.2509 3.28e-16 8fkp:NB, 8fku:NB, 8fkv:NB, 8fkw:NB, 8fkx:NB, 8fky:NB, 8fkz:NB, 8fl0:NB, 8ink:u, 8ipd:u, 8ipx:u, 8ipy:u
10 6n8n:W 377 180 0.1903 0.1459 0.3056 2.58e-14 6n8o:W
11 6qtz:o 325 173 0.1834 0.1631 0.3064 2.05e-13 6qik:o, 6ri5:o, 6rzz:o, 6s05:o
12 5t62:W 306 190 0.2076 0.1961 0.3158 9.23e-13
13 6n8j:m 378 253 0.2145 0.1640 0.2451 9.21e-12
14 7btb:m 469 253 0.2145 0.1322 0.2451 9.59e-12 7bt6:m, 6ft6:m, 3jct:m, 6m62:m, 7oh3:m, 7ohq:m, 7oht:m, 7ug6:m, 7uoo:m, 7uqb:m, 7uqz:m, 7uui:m, 7v08:m, 6ylg:m, 6ylh:m
15 8fl2:NC 511 253 0.2180 0.1233 0.2490 3.18e-11 8fkz:NC, 8fl0:NC, 8fl3:NC, 8fl4:NC, 8idt:A, 8idy:A, 8ie3:A, 8ine:A, 8inf:A, 8ink:w, 8ipd:w, 8ipx:w, 8ipy:w, 8ir1:w, 8ir3:w
16 8pv1:Cd 462 254 0.2007 0.1255 0.2283 1.08e-10 8pv2:Cd, 8pv3:Cd, 8pv4:Cd, 8pv5:Cd, 8pv6:Cd, 8pv7:Cd, 8pv8:Cd, 8pvk:Cd, 8pvl:Cd
17 8i9w:CL 397 194 0.1834 0.1335 0.2732 1.35e-10 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL
18 7of1:m 229 153 0.1453 0.1834 0.2745 6.12e-08
19 6lsr:1 247 119 0.1315 0.1538 0.3193 2.62e-06
20 1xzq:A 449 98 0.1073 0.0690 0.3163 2.84e-06 1xzq:B
21 1xzq:A 449 127 0.1211 0.0780 0.2756 4.82e-04 1xzq:B
22 7am2:BV 199 68 0.0865 0.1256 0.3676 3.90e-05
23 2qu8:A 194 162 0.1384 0.2062 0.2469 4.25e-05
24 3j8g:X 418 163 0.1488 0.1029 0.2638 9.97e-05
25 3j8g:X 418 26 0.0484 0.0335 0.5385 1.3
26 1mky:A 407 164 0.1488 0.1057 0.2622 1.13e-04
27 1mky:A 407 51 0.0727 0.0516 0.4118 0.005
28 6yxy:EQ 471 52 0.0761 0.0467 0.4231 2.59e-04
29 5m7h:A 420 133 0.1142 0.0786 0.2481 2.69e-04 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
30 5m7h:A 420 50 0.0692 0.0476 0.4000 0.12 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
31 5dn8:A 405 60 0.0865 0.0617 0.4167 2.84e-04
32 5dn8:A 405 128 0.1142 0.0815 0.2578 0.022
33 8fl4:SR 593 98 0.0934 0.0455 0.2755 3.28e-04 8fkr:SR, 8fks:SR
34 3a1s:A 255 77 0.0865 0.0980 0.3247 3.47e-04 3a1s:B, 3a1t:A, 3a1u:A, 3a1u:B
35 8ir1:4 620 98 0.0934 0.0435 0.2755 3.57e-04 8fkt:SR, 8fku:SR, 8fkv:SR, 8fkw:SR, 8fkx:SR, 8fky:SR, 8fkz:SR, 8fl0:SR, 8fl2:SR, 8fl3:SR, 8fl6:SR, 8fl7:SR, 8fl9:SR, 8fla:SR, 8flb:SR, 8flc:SR, 8fld:SR, 8fle:SR, 8flf:SR, 8idt:4, 8idy:4, 8ie3:4, 8ine:4, 8inf:4, 8ink:4, 8ipd:4, 8ipx:4, 8ipy:4, 8ir3:4, 6lss:4, 6lu8:4
36 3w5j:A 194 66 0.0796 0.1186 0.3485 6.84e-04
37 2wjg:A 170 53 0.0761 0.1294 0.4151 0.001 2wjg:B, 2wjh:A, 2wjh:B, 2wji:A, 2wji:B, 2wjj:A, 2wjj:B
38 7nrc:So 347 86 0.0830 0.0692 0.2791 0.002
39 2cxx:A 184 80 0.1003 0.1576 0.3625 0.002 2cxx:B, 2cxx:C
40 1svw:A 190 66 0.0761 0.1158 0.3333 0.002 1svi:A, 1svw:B
41 3iev:A 302 62 0.0969 0.0927 0.4516 0.003 7c1o:A, 3r9w:A, 3r9x:A
42 6xrs:B 392 155 0.1280 0.0944 0.2387 0.003 6xrs:A, 6xrs:D, 6xrs:C
43 6xrs:B 392 68 0.0830 0.0612 0.3529 0.096 6xrs:A, 6xrs:D, 6xrs:C
44 8csq:a 263 54 0.0761 0.0837 0.4074 0.005
45 3i8x:B 261 52 0.0692 0.0766 0.3846 0.005 3hyt:A, 3hyt:B, 3hyt:C, 3i8x:A, 3i8x:C, 4r98:A, 4r98:B
46 2e87:A 356 74 0.1038 0.0843 0.4054 0.006
47 2e87:A 356 64 0.0727 0.0590 0.3281 0.034
48 3ec1:A 311 57 0.0727 0.0675 0.3684 0.006 3ec1:B
49 1u0l:A 278 160 0.1488 0.1547 0.2687 0.007 1u0l:B, 1u0l:C
50 7ohy:b 375 101 0.0865 0.0667 0.2475 0.009
51 8etc:b 415 109 0.0969 0.0675 0.2569 0.014 8esq:b, 8etj:b
52 8eti:b 391 109 0.0969 0.0716 0.2569 0.015 8esr:b, 8etg:b
53 2dyk:A 150 53 0.0761 0.1467 0.4151 0.019 2dyk:B
54 2gj8:D 172 70 0.0796 0.1337 0.3286 0.024 2gj8:A, 2gj8:B, 2gj8:C, 2gj9:A, 2gj9:B, 2gj9:C, 2gj9:D, 2gja:A, 2gja:B
55 1wf3:A 296 79 0.1003 0.0980 0.3671 0.025
56 2wib:A 261 52 0.0692 0.0766 0.3846 0.026 2wib:B, 2wic:A
57 3ieu:A 293 54 0.0830 0.0819 0.4444 0.026 3ieu:B
58 7rr5:R 355 85 0.0969 0.0789 0.3294 0.030
59 8pv1:CH 627 115 0.0969 0.0447 0.2435 0.032 8i9r:CH, 8i9t:CH, 8i9v:CH, 8i9w:CH, 8i9x:CH, 8i9y:CH, 8i9z:CH, 8ia0:CH, 8pv2:CH, 8pv3:CH, 8pv4:CH, 8pv5:CH, 8pv6:CH, 8pv7:CH, 8pv8:CH, 8pvk:CH, 8pvl:CH
60 7y9i:A 362 21 0.0554 0.0442 0.7619 0.035
61 3pqc:B 194 60 0.0727 0.1082 0.3500 0.038 3pqc:A
62 3b1v:A 264 52 0.0657 0.0720 0.3654 0.038 3b1w:A, 3b1w:B, 3b1w:C, 3b1w:D, 3b1x:A, 3b1x:B, 3b1y:A, 7bvu:A, 7bvu:B, 7bwv:A, 7bwv:B, 3lx5:A, 3lx8:A, 4non:A, 4non:B, 3ss8:A, 3ss8:B, 3tah:A, 3tah:B
63 8v83:b 423 65 0.0692 0.0473 0.3077 0.049 6elz:b, 6em1:b, 6em5:b, 7ohp:b, 7ohr:b, 7ohs:b, 7ohu:b, 7ohv:b, 8v84:b
64 5cyp:D 227 49 0.0727 0.0925 0.4286 0.058
65 6ylg:b 613 65 0.0692 0.0326 0.3077 0.066 7nac:b, 7of1:b, 7r7a:b, 6ylh:b
66 8hfr:rA 647 65 0.0692 0.0309 0.3077 0.068 7bt6:b, 7btb:b, 6c0f:W, 6ft6:b, 3jct:b, 5jcs:o, 6m62:b, 6n8j:b, 6n8k:b, 7nad:b, 7oh3:b, 7ohq:b, 7oht:b, 7r72:b, 7u0h:b, 7ug6:b, 7uoo:b, 7uqb:b, 7uqz:b, 7v08:b, 4v7f:o, 8v87:b, 6ylx:b, 6yly:b, 7z34:b
67 8kie:y 363 26 0.0519 0.0413 0.5769 0.074
68 8r1a:A 587 59 0.0830 0.0409 0.4068 0.075 2b8w:A, 2b8w:B, 2b92:A, 2b92:B, 2bc9:A, 8cqb:A, 8cqb:B, 2d4h:A, 1f5n:A, 6loj:B, 8r1a:B, 8r1a:C, 8r1a:D, 8r1a:E, 8r1a:F
69 3h2y:A 309 86 0.0934 0.0874 0.3140 0.081
70 7am2:BU 463 88 0.0796 0.0497 0.2614 0.085
71 2d4h:B 284 61 0.0830 0.0845 0.3934 0.17
72 6yxx:EA 532 89 0.0865 0.0470 0.2809 0.19 7aoi:XL, 6yxy:EA
73 3geh:A 442 75 0.0865 0.0566 0.3333 0.22
74 5cyo:A 272 64 0.0761 0.0809 0.3438 0.26 5cyo:B, 4yqf:B, 4yqf:A
75 6vs4:A 223 57 0.0727 0.0942 0.3684 0.29 6vs4:B
76 4jyb:A 323 24 0.0484 0.0433 0.5833 0.34 8dpb:A, 8dpb:B, 4jyb:B, 4jyc:D, 4lc1:A, 4lc1:B, 2qm7:A, 2qm7:B
77 2dby:A 355 18 0.0450 0.0366 0.7222 0.35
78 7odt:t 316 58 0.0727 0.0665 0.3621 0.35
79 5ee3:B 364 21 0.0484 0.0385 0.6667 0.46 5ee3:A, 5ee9:A
80 2www:D 314 88 0.0830 0.0764 0.2727 0.81 2www:A, 2www:B, 2www:C
81 8peu:A 419 130 0.1038 0.0716 0.2308 1.2 1a8v:A, 1a8v:B, 2a8v:A, 2a8v:B, 7adb:a, 7adb:b, 7adb:c, 7adb:d, 7adb:e, 7adb:f, 7adc:a, 7adc:b, 7adc:f, 7adc:c, 7adc:d, 7adc:e, 7add:a, 7add:f, 7add:b, 7add:c, 7add:d, 7add:e, 7ade:a, 7ade:f, 7ade:b, 7ade:c, 7ade:d, 7ade:e, 6duq:A, 6duq:B, 6duq:F, 6duq:E, 6duq:L, 6duq:G, 6duq:H, 6duq:K, 6duq:C, 6duq:I, 6duq:D, 6duq:J, 8e3h:e, 8e3h:f, 8e3h:c, 8e3h:b, 8e3h:a, 8e3h:d, 8e5l:e, 8e5l:f, 8e5l:c, 8e5l:b, 8e5l:a, 8e5l:d, 8e5p:e, 8e5p:f, 8e5p:c, 8e5p:b, 8e5p:a, 8e5p:d, 8e6w:e, 8e6w:f, 8e6w:c, 8e6w:b, 8e6w:a, 8e6w:d, 8e70:e, 8e70:f, 8e70:c, 8e70:b, 8e70:a, 8e70:d, 2ht1:B, 2ht1:A, 3ice:A, 3ice:B, 3ice:C, 3ice:D, 3ice:E, 3ice:F, 5jji:A, 5jji:B, 5jji:C, 5jji:D, 5jji:E, 5jji:F, 5jjk:A, 5jjk:B, 5jjk:C, 5jjk:D, 5jjk:E, 5jjk:F, 5jjl:A, 5jjl:B, 5jjl:C, 5jjl:D, 5jjl:E, 5jjl:F, 8peu:B, 8peu:C, 8peu:D, 8peu:E, 8peu:F, 8peu:I, 8peu:J, 8peu:K, 8peu:L, 8peu:M, 8pew:A, 8pew:B, 8pew:C, 8pew:D, 8pew:E, 8pew:F, 8pew:G, 8pew:H, 8pew:I, 8pew:J, 8pew:K, 8pew:L, 8pew:M, 8pew:N, 8pew:O, 8pew:P, 8pex:A, 8pex:B, 8pex:C, 8pex:D, 8pex:E, 8pex:F, 8pex:I, 8pex:J, 8pex:K, 8pex:L, 8pex:M, 8pex:N, 8pey:B, 8pey:C, 8pey:D, 8pey:E, 8pey:F, 8pey:G, 8pey:A, 8pey:J, 8pey:K, 8pey:L, 8pey:M, 8pey:N, 8ptg:A, 8ptg:B, 8ptg:C, 8ptg:D, 8ptg:E, 8ptg:F, 8ptm:C, 8ptm:D, 8ptm:E, 8pto:B, 8pto:C, 8pto:D, 1pv4:A, 1pv4:C, 1pv4:D, 1pv4:E, 1pv4:F, 1pvo:A, 1pvo:C, 1pvo:D, 1pvo:E, 1pvo:F, 1pvo:B, 8q3n:A, 8q3n:B, 8q3n:C, 8q3n:D, 8q3n:E, 8q3n:F, 8q3o:A, 8q3o:B, 8q3o:C, 8q3o:D, 8q3o:E, 8q3p:a, 8q3p:r, 8q3p:q, 8q3p:p, 8q3p:o, 8q3p:n, 8q3p:m, 8q3p:l, 8q3p:k, 8q3p:j, 8q3p:i, 8q3p:b, 8q3p:c, 8q3p:d, 8q3p:e, 8q3p:f, 8q3p:g, 8q3p:h, 8q3q:a, 8q3q:r, 8q3q:q, 8q3q:p, 8q3q:o, 8q3q:n, 8q3q:m, 8q3q:l, 8q3q:k, 8q3q:j, 8q3q:i, 8q3q:h, 8q3q:g, 8q3q:f, 8q3q:e, 8q3q:d, 8q3q:c, 8q3q:b, 6wa8:A, 6wa8:B, 6wa8:C, 6wa8:D, 6wa8:E, 6wa8:F, 6xas:B, 6xas:C, 6xas:D, 6xas:E, 6xas:F, 6xav:B, 1xpo:A, 1xpo:B, 1xpo:C, 1xpo:D, 1xpo:E, 1xpo:F, 1xpr:A, 1xpr:B, 1xpr:C, 1xpr:D, 1xpr:E, 1xpr:F, 1xpu:A, 1xpu:B, 1xpu:C, 1xpu:D, 1xpu:E, 1xpu:F, 6z9p:a, 6z9p:b, 6z9p:c, 6z9p:d, 6z9p:e, 6z9p:f, 6z9q:a, 6z9q:f, 6z9q:b, 6z9q:c, 6z9q:d, 6z9q:e, 6z9r:a, 6z9r:f, 6z9r:b, 6z9r:c, 6z9r:d, 6z9r:e, 6z9s:a, 6z9s:f, 6z9s:b, 6z9s:c, 6z9s:d, 6z9s:e, 6z9t:a, 6z9t:f, 6z9t:b, 6z9t:c, 6z9t:d, 6z9t:e
82 8pey:I 380 130 0.1038 0.0789 0.2308 1.3
83 8hsr:C 367 33 0.0450 0.0354 0.3939 1.4 8hsj:A, 8hsj:B, 8hsj:C, 8hsj:D, 8hsj:E, 8hsj:F, 8hsl:A, 8hsl:B, 8hsl:C, 8hsl:D, 8hsl:E, 8hsl:F, 8hsr:A, 8hsr:B, 8hsr:F, 8hsr:D, 8hsr:E
84 3izy:P 537 60 0.0692 0.0372 0.3333 1.4
85 8gju:F 332 84 0.0796 0.0693 0.2738 1.5 8gju:D, 8gju:A, 8gju:B
86 6gaw:BC 571 62 0.0692 0.0350 0.3226 1.8 6gaz:BC, 6gb2:BC, 7po2:7, 8qrn:7, 6rw5:7
87 2yv5:A 293 122 0.0969 0.0956 0.2295 1.9
88 2ohf:A 327 22 0.0415 0.0367 0.5455 2.3
89 7owj:F 197 23 0.0346 0.0508 0.4348 2.6 7owe:E, 7owe:F, 7owe:D, 7owe:A, 7owe:B, 7owe:C, 7owj:A, 7owj:B, 7owj:C, 7owj:D, 7owj:E, 7owk:B, 7owk:A, 7owk:C, 7owk:D, 7owk:E, 7owk:F, 7owl:A, 7owl:B, 7owl:C, 7owl:D, 7owl:E, 7owl:F
90 4zi2:A 185 36 0.0415 0.0649 0.3333 2.7 3bh6:A, 3bh7:A, 1fzq:A, 4goj:A, 4goj:B, 7ok7:A, 7ok7:B, 7ok7:C, 7ok7:D, 7ok7:E, 7ok7:F, 4zi2:B, 4zi3:A, 4zi3:B
91 6xyw:AO 452 45 0.0450 0.0288 0.2889 3.0
92 4kjz:C 458 96 0.0969 0.0611 0.2917 3.1 4b43:A, 4b44:A, 4b47:A, 4b48:A, 4kjz:A
93 7e5a:B 471 59 0.0761 0.0467 0.3729 3.1 7e5a:A
94 5cyp:A 248 54 0.0657 0.0766 0.3519 3.2 5cyp:B, 5cyp:C
95 6k1z:A 544 120 0.1107 0.0588 0.2667 3.2
96 7ckf:A 256 67 0.0830 0.0938 0.3582 3.2 7ckf:B
97 6uqq:C 280 65 0.0657 0.0679 0.2923 4.1 3sop:A, 3sop:B, 6uqq:D, 4z51:A, 4z54:A, 4z54:B
98 6v11:C 503 58 0.0692 0.0398 0.3448 4.3 6v11:A, 6v11:B, 6v11:F
99 7cq3:A 298 52 0.0554 0.0537 0.3077 4.4 7cq2:B, 7cq4:A
100 2qag:C 224 67 0.0830 0.1071 0.3582 4.4
101 6vkj:A 305 59 0.0761 0.0721 0.3729 4.5
102 5ady:6 426 47 0.0554 0.0376 0.3404 4.6 8g31:6, 8g34:6, 8g38:6, 7yla:6
103 3tw4:A 218 49 0.0588 0.0780 0.3469 4.7 3tw4:B
104 3tk1:A 293 28 0.0554 0.0546 0.5714 4.7
105 2iyv:A 179 23 0.0415 0.0670 0.5217 5.0 3baf:A, 4bqs:A, 4bqs:B, 4bqs:C, 2dfn:A, 2dft:A, 2dft:B, 2dft:C, 2dft:D, 2g1k:A, 2iyq:A, 2iyr:A, 2iyr:B, 2iys:A, 2iyu:A, 2iyw:A, 2iyx:A, 2iyy:A, 2iyz:A, 1l4u:A, 1l4y:A, 1u8a:A, 1we2:A, 1zyu:A
106 3tk1:B 319 28 0.0554 0.0502 0.5714 5.2
107 6mq9:B 267 60 0.0623 0.0674 0.3000 5.6 6mq9:A, 6mq9:D, 6mq9:C, 6mqb:A, 6mqk:A, 6mqk:D, 6mqk:B, 6mqk:C, 6mql:A
108 7cq2:A 274 52 0.0554 0.0584 0.3077 6.0
109 8dkt:A 264 67 0.0727 0.0795 0.3134 6.3
110 7mq8:SI 844 27 0.0450 0.0154 0.4815 7.7 7mq9:SI
111 7mqa:SI 803 27 0.0450 0.0162 0.4815 8.1
112 5ksz:A 398 52 0.0450 0.0327 0.2500 8.3 5kso:A, 5ksp:A, 5ksp:B, 5ksy:A, 5kty:A, 5ku1:A
113 5lmv:a 502 68 0.0761 0.0438 0.3235 8.6
114 4c0r:A 239 74 0.0588 0.0711 0.2297 8.7 4c0r:B
115 3gee:A 427 21 0.0381 0.0258 0.5238 8.8
116 7rll:B 177 28 0.0381 0.0621 0.3929 9.2 7rll:A
117 6rxt:CI 822 26 0.0450 0.0158 0.5000 9.7 6rxu:CI, 6rxv:CI, 6rxx:CI, 6rxy:CI, 6rxz:CI

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218