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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VIPKKNVPTSKRETYTEDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDIDRAIAYLFPSGLFEKRARPVMKHPEQIFPR
QRAIQWGEDGRPFHYLFYTGKQSYYSLMHDVYGMLLNLEKHQVIGSRWLIKEELEEMLVEKLSDLDYMQFIRLLEKLLTS
QCGAAEEEFVQRFRRSVTLESKKQLIEPVQYDEQGMAFSKSEGKRKTAKAEAIVYKHGSGRIKVNGIDYQLYFPITQDRE
QLMFPFHFVDRLGKHDVTCTVSGGGRSAQAGAIRLAMAKALCSFVTEDEVEWMRQAGLLTTDPRVRERKKPGQEGARRKF
TWKKR

The query sequence (length=325) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7p2e:G 330 325 1.0000 0.9848 1.0000 0.0 7a5f:G6, 7a5g:G6, 7a5i:G6, 7a5k:G6, 8any:AG, 8csp:G, 8csq:G, 8csr:G, 8css:G, 8cst:G, 8csu:G, 3j9m:AG, 8k2a:SI, 7l08:AG, 6nu2:AG, 6nu3:AG, 7og4:AG, 8oir:Ag, 8ois:Ag, 7pnx:G, 7pny:G, 7pnz:G, 7po0:G, 7po1:G, 7po2:G, 7po3:G, 7qi4:AG, 7qi5:AG, 7qi6:AG, 8qrk:G, 8qrl:G, 8qrm:G, 8qrn:G, 6rw4:G, 6rw5:G, 6vlz:AG, 6vmi:AG, 8xt0:SI, 8xt2:SI, 6zm5:AG, 6zm6:AG, 6zs9:AG, 6zsa:AG, 6zsb:AG, 6zsc:AG, 6zsd:AG, 6zse:AG, 6zsg:AG
2 7pnt:G 325 325 0.8523 0.8523 0.8523 0.0 7pnu:G, 7pnv:G, 7pnw:G
3 6gaw:AI 328 328 0.8215 0.8140 0.8140 0.0 5aj3:I, 5aj4:AI, 6gaz:AI, 7nqh:AI, 7nql:AI, 7nsi:AI, 7nsj:AI, 8oin:Ag, 8oip:Ag, 6ydp:AI, 6ydw:AI
4 3jd5:I 311 311 0.8062 0.8424 0.8424 0.0 6neq:I, 6nf8:I
5 6xyw:Bh 123 120 0.1477 0.3902 0.4000 8.67e-23
6 6yw5:II 247 232 0.2308 0.3036 0.3233 3.45e-22 6ywe:II, 6ywx:II, 6ywy:II
7 8fmw:I 131 130 0.1538 0.3817 0.3846 1.24e-20
8 8uu5:i 127 123 0.1569 0.4016 0.4146 1.29e-20 7nhn:j, 8uu4:i, 8uu6:i, 8uu7:i, 8uu8:i, 8uu9:i
9 7nhk:j 128 123 0.1569 0.3984 0.4146 2.25e-19 6o8w:i, 6o8x:i, 6o8y:i, 6o8z:i, 6o90:i, 7p7q:j, 7p7r:j, 7p7s:j, 7p7t:j, 7p7u:j, 6w6p:i, 6wua:i
10 8om2:I 231 174 0.1908 0.2684 0.3563 3.11e-19 8d8k:I, 8d8l:I, 5mrc:II, 5mre:II, 5mrf:II, 8om3:I, 8om4:I
11 8a22:Bi 282 209 0.2215 0.2553 0.3445 7.14e-19 8apn:Bi, 8apo:Bi
12 5myj:AI 129 123 0.1569 0.3953 0.4146 1.80e-18
13 8bh6:i 128 129 0.1569 0.3984 0.3953 3.87e-18 7aso:H, 7asp:q, 7bge:i, 8bh7:i, 8byv:i, 6fxc:Ai, 6fxc:Bi, 7kwg:i, 5li0:i, 5nd8:i, 5nd9:i, 5ngm:Ai, 7nhl:j, 7nhm:j, 8p2f:j, 8p2g:j, 8p2h:j, 7p48:i, 6s0x:i, 6s13:i, 5tcu:SH, 8y38:i, 8y39:i, 6yef:i
14 4v6g:AL 128 123 0.1508 0.3828 0.3984 1.62e-17 5a9z:BM, 5aa0:BM, 4aqy:I, 7azo:S9A, 7azo:S9B, 7azs:S9A, 7azs:S9B, 9b00:1i, 9b00:2i, 4b3m:I, 4b3r:I, 4b3s:I, 4b3t:I, 6b4v:RA, 6b4v:VC, 6boh:SA, 6boh:XC, 6bok:QA, 6bok:TC, 5br8:I, 6buw:QI, 6buw:XI, 6bz6:QI, 6bz6:XI, 6bz7:QI, 6bz7:XI, 6bz8:QI, 6bz8:XI, 6c5l:AI, 6c5l:CI, 6cae:1i, 6cae:2i, 6cao:I, 6cap:I, 6caq:I, 6car:I, 6cas:I, 6cfj:1i, 6cfj:2i, 6cfk:1i, 6cfk:2i, 6cfl:1i, 6cfl:2i, 8cvj:1i, 8cvj:2i, 8cvk:1i, 8cvk:2i, 8cvl:1i, 8cvl:2i, 5czp:XI, 5czp:QI, 6czr:1i, 6czr:2i, 5d8b:JA, 5d8b:FC, 5dfe:XI, 5dfe:QI, 5dox:1i, 5dox:2i, 5doy:1i, 5doy:2i, 4dr1:I, 4dr2:I, 4dr3:I, 4dr4:I, 4dr5:I, 4dr6:I, 4dr7:I, 6dti:I, 4duy:I, 4duz:I, 7dug:I, 7duh:I, 7dui:I, 7duj:I, 7duk:I, 7dul:I, 4dv0:I, 4dv1:I, 4dv2:I, 4dv3:I, 4dv4:I, 4dv5:I, 4dv6:I, 4dv7:I, 2e5l:I, 5e7k:8E, 5e7k:82, 5e81:8E, 5e81:82, 8ekb:1i, 8ekb:2i, 5el4:8E, 5el4:82, 5el5:8E, 5el5:82, 5el6:8E, 5el6:82, 5el7:8E, 5el7:82, 8ev6:1i, 8ev6:2i, 8ev7:1i, 8ev7:2i, 2f4v:I, 5f8k:1i, 5f8k:2i, 8fc1:1i, 8fc1:2i, 8fc2:1i, 8fc2:2i, 8fc3:1i, 8fc3:2i, 8fc4:1i, 8fc4:2i, 8fc5:1i, 8fc5:2i, 8fc6:1i, 8fc6:2i, 5fdu:1i, 5fdu:2i, 5fdv:1i, 5fdv:2i, 1fjg:I, 6fkr:1i, 6fkr:2i, 8fom:QI, 8fom:XI, 8fon:QI, 8fon:XI, 8g29:1i, 8g29:2i, 8g2a:1i, 8g2a:2i, 8g2b:1i, 8g2b:2i, 8g2c:1i, 8g2c:2i, 8g2d:1i, 8g2d:2i, 4gkj:I, 4gkk:I, 6gsj:8E, 6gsj:82, 6gsk:8E, 6gsk:82, 6gsl:8E, 6gsl:82, 6gzq:I2, 6gzx:I3, 6gzx:I4, 6gzz:I3, 6gzz:I4, 5hau:1i, 5hau:2i, 5hcp:1i, 5hcp:2i, 5hcq:1i, 5hcq:2i, 5hcr:1i, 5hcr:2i, 5hd1:1i, 5hd1:2i, 2hhh:I, 1hnw:I, 1hnx:I, 1hnz:I, 1hr0:I, 1i94:I, 1i95:I, 1i96:I, 1i97:I, 1ibk:I, 1ibl:I, 1ibm:I, 5ib7:8E, 5ib7:82, 5ib8:8E, 5ib8:82, 5ibb:8E, 5ibb:82, 5imq:M, 5imr:M, 5iwa:I, 5j30:QI, 5j30:XI, 5j3c:QI, 5j3c:XI, 5j4b:1i, 5j4b:2i, 5j4c:1i, 5j4c:2i, 5j4d:RA, 5j4d:WC, 1j5e:I, 5j8b:i, 4ji0:I, 4ji1:I, 4ji2:I, 4ji3:I, 4ji4:I, 4ji5:I, 4ji6:I, 4ji7:I, 4ji8:I, 7jql:1i, 7jql:2i, 7jqm:1i, 7jqm:2i, 4jv5:I, 4jya:I, 4k0k:I, 4khp:I, 4kvb:I, 4l47:QI, 4l47:XI, 4l71:QI, 4l71:XI, 4lel:QI, 4lel:XI, 4lf4:I, 4lf5:I, 4lf6:I, 4lf7:I, 4lf8:I, 4lf9:I, 4lfa:I, 4lfb:I, 4lfc:I, 4lfz:QI, 4lfz:XI, 7lh5:AI, 7lh5:CI, 5lmn:I, 5lmo:I, 5lmp:I, 5lmq:I, 5lmr:I, 5lms:I, 5lmt:I, 5lmu:I, 5lmv:I, 4lnt:QI, 4lnt:XI, 4lsk:QI, 4lsk:XI, 4lt8:QI, 4lt8:XI, 7md7:1i, 7md7:2i, 6mkn:I, 6mpf:I, 6mpi:I, 6n1d:AS09, 6n1d:BS09, 1n32:I, 1n33:I, 1n34:I, 1n36:I, 6n9e:1i, 6n9e:2i, 6n9f:1i, 6n9f:2i, 5ndj:8E, 5ndj:82, 5ndk:8E, 5ndk:82, 6nd5:1i, 6nd5:2i, 6nd6:1i, 6nd6:2i, 6ndk:QI, 6ndk:XI, 6nsh:QI, 6nsh:XI, 6nta:QI, 6nta:XI, 6nuo:QI, 6nuo:XI, 6nwy:QI, 6nwy:XI, 4nxm:I, 4nxn:I, 6ny6:I, 6o3m:QI, 6o3m:XI, 6o97:1i, 6o97:2i, 6of1:1i, 6of1:2i, 6of6:QI, 6of6:XI, 6oj2:QI, 6oj2:XI, 6ope:QI, 6ope:XI, 6ord:QI, 6ord:XI, 6osi:QI, 6osi:XI, 3oto:I, 5ot7:H, 6otr:QI, 6otr:XI, 4ox9:I, 6oxa:QI, 6oxa:XI, 6oxi:QI, 6oxi:XI, 4p6f:QI, 4p6f:XI, 4p70:QI, 4p70:XI, 6q95:n, 6qnq:8E, 6qnq:82, 6qnr:8E, 6qnr:82, 7rq8:1i, 7rq8:2i, 7rq9:1i, 7rq9:2i, 7rqa:1i, 7rqa:2i, 7rqb:1i, 7rqb:2i, 7rqc:1i, 7rqc:2i, 7rqd:1i, 7rqd:2i, 7rqe:1i, 7rqe:2i, 3t1h:I, 3t1y:I, 8t8b:1i, 8t8b:2i, 8t8c:1i, 8t8c:2i, 4tua:QI, 4tua:XI, 4tub:QI, 4tub:XI, 4tuc:QI, 4tuc:XI, 4tud:QI, 4tud:XI, 4tue:QI, 4tue:XI, 7u2h:1i, 7u2h:2i, 7u2i:1i, 7u2i:2i, 7u2j:1i, 7u2j:2i, 6ucq:1i, 6ucq:2i, 8ud6:1i, 8ud6:2i, 8ud7:1i, 8ud7:2i, 8ud8:1i, 8ud8:2i, 6uo1:1i, 6uo1:2i, 5uq7:i, 5uq8:i, 2uu9:I, 2uua:I, 2uub:I, 2uuc:I, 8uvr:1i, 8uvr:2i, 8uvs:1i, 8uvs:2i, 2uxb:I, 2uxc:I, 2uxd:I, 7v2l:I, 7v2m:I, 7v2n:I, 7v2o:I, 7v2p:I, 7v2q:I, 4v49:AI, 4v4a:AI, 4v4g:AI, 4v4g:CI, 4v4g:EI, 4v4g:GI, 4v4g:II, 4v4i:j, 4v4j:j, 4v4p:BL, 4v4r:AI, 4v4s:AI, 4v4t:AI, 4v4x:AL, 4v4y:AL, 4v4z:AL, 4v51:AI, 4v51:CI, 4v5a:AI, 4v5a:CI, 4v5c:AI, 4v5c:CI, 4v5d:AI, 4v5d:CI, 4v5e:AI, 4v5e:CI, 4v5f:AI, 4v5f:CI, 4v5g:AI, 4v5g:CI, 4v5j:AI, 4v5j:CI, 4v5k:AI, 4v5k:CI, 4v5l:AI, 4v5m:AI, 4v5n:AI, 4v5p:AI, 4v5p:CI, 4v5q:AI, 4v5q:CI, 4v5r:AI, 4v5r:CI, 4v5s:AI, 4v5s:CI, 4v63:AI, 4v63:CI, 4v67:AI, 4v67:CI, 4v68:AI, 4v6a:AI, 4v6a:CI, 4v6f:BL, 4v6f:CL, 4v6g:CL, 4v7j:Ai, 4v7j:Bi, 4v7k:Ai, 4v7k:Bi, 4v7l:AI, 4v7l:CI, 4v7m:AI, 4v7m:CI, 4v7p:AI, 4v7p:DI, 4v7w:AI, 4v7w:CI, 4v7x:AI, 4v7x:CI, 4v7y:AI, 4v7y:CI, 4v7z:AI, 4v7z:CI, 4v83:AI, 4v83:CI, 4v84:AI, 4v84:CI, 4v87:BL, 4v87:CL, 4v8a:CI, 4v8a:DI, 4v8b:AL, 4v8b:CL, 4v8c:CL, 4v8c:DL, 4v8d:AL, 4v8d:CL, 4v8e:BL, 4v8e:DL, 4v8f:BL, 4v8f:CL, 4v8g:AI, 4v8g:CI, 4v8h:AI, 4v8h:CI, 4v8i:AI, 4v8i:CI, 4v8j:AI, 4v8j:CI, 4v8n:AI, 4v8n:CI, 4v8o:AI, 4v8q:BI, 4v8u:AI, 4v8u:CI, 4v8x:AI, 4v8x:CI, 5v8i:1i, 5v8i:2i, 4v90:AI, 4v95:AI, 4v95:CI, 4v97:AI, 4v97:CI, 4v9a:AL, 4v9a:CL, 4v9b:AL, 4v9b:CL, 4v9h:AI, 4v9i:AI, 4v9i:CI, 4v9j:AI, 4v9j:CI, 4v9k:AI, 4v9k:CI, 4v9l:AI, 4v9l:CI, 4v9m:AI, 4v9m:CI, 4v9n:AI, 4v9n:CI, 4v9q:BI, 4v9q:DI, 4v9r:AI, 4v9r:CI, 4v9s:AI, 4v9s:CI, 5vp2:1i, 5vp2:2i, 5vpo:QI, 5vpo:XI, 5vpp:QI, 5vpp:XI, 2vqe:I, 2vqf:I, 8vtu:1i, 8vtu:2i, 8vtv:1i, 8vtv:2i, 8vtw:1i, 8vtw:2i, 8vtx:1i, 8vtx:2i, 8vty:1i, 8vty:2i, 1vvj:QI, 1vvj:XI, 1vy4:AI, 1vy4:CI, 1vy5:AI, 1vy5:CI, 1vy6:AI, 1vy6:CI, 1vy7:AI, 1vy7:CI, 4w29:AI, 4w29:CI, 4w2e:i, 4w2f:AI, 4w2f:CI, 4w2g:AI, 4w2g:CI, 4w2h:AI, 4w2h:CI, 4w2i:AI, 4w2i:CI, 4w4g:QI, 4w4g:XI, 5w4k:1i, 5w4k:2i, 5wis:1i, 5wis:2i, 5wit:1i, 5wit:2i, 5wnp:I, 5wnq:I, 5wnr:I, 5wns:I, 5wnt:I, 5wnu:I, 5wnv:I, 4wpo:BI, 4wpo:DI, 4wq1:8E, 4wq1:82, 4wqf:BI, 4wqf:DI, 4wqr:8E, 4wqr:82, 4wqu:BI, 4wqu:DI, 4wqy:BI, 4wqy:DI, 4wr6:8E, 4wr6:82, 4wra:8E, 4wra:82, 4wro:8E, 4wsd:8E, 4wsd:82, 4wsm:8E, 4wsm:82, 4wt1:8E, 4wt1:82, 4wt8:AI, 4wt8:BI, 4wu1:8E, 4wu1:82, 4wzd:8E, 4wzd:82, 4wzo:8E, 4wzo:82, 4x62:I, 4x64:I, 4x65:I, 4x66:I, 4xej:AS09, 4xej:BS09, 6xhv:1i, 6xhv:2i, 6xhw:1i, 6xhw:2i, 6xhx:1i, 6xhx:2i, 6xhy:1i, 6xhy:2i, 1xmo:I, 1xmq:I, 1xnq:I, 1xnr:I, 6xqd:1i, 6xqd:2i, 6xqe:1i, 6xqe:2i, 4y4o:1i, 4y4o:2i, 4y4p:1i, 4y4p:2i, 4yhh:I, 4ypb:QI, 4ypb:XI, 4yy3:I, 4yzv:QI, 4yzv:XI, 4z3s:1i, 4z3s:2i, 4z8c:1i, 4z8c:2i, 4zer:1i, 4zer:2i, 5zlu:O, 2zm6:I, 4zsn:QI, 4zsn:XI
15 3j9w:AI 130 126 0.1538 0.3846 0.3968 1.06e-16 8buu:i, 8cdu:J, 8cdv:J, 8cec:N, 8ced:J, 8cee:J, 6ha1:i, 6ha8:i, 6htq:i, 5njt:I, 7o5b:I, 8qcq:i, 7qgu:n, 7qh4:m, 8qpp:I, 7qv1:i, 7qv2:i, 7qv3:i, 8r55:I
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22 7pkq:i 154 126 0.1292 0.2727 0.3333 2.55e-11
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38 6zj3:SL 143 157 0.1662 0.3776 0.3439 1.21e-07
39 5jb3:K 135 123 0.1169 0.2815 0.3089 1.83e-07 5jbh:K, 6skf:Al, 6skg:Al, 6sw9:K, 6swc:K, 6swe:K, 6th6:Al, 4v4n:BK, 4v6u:AK, 7zag:K, 7zah:K, 7zai:K, 7zhg:K
40 3j7a:M 138 130 0.1323 0.3116 0.3308 2.26e-07 3jbn:M, 3jbo:M, 3jbp:M, 6okk:M, 8tpu:SM
41 5xxu:Q 138 132 0.1477 0.3478 0.3636 4.14e-07
42 8r57:Q 145 130 0.1385 0.3103 0.3462 6.96e-07 8ip8:la, 8ip9:la, 8ipa:la, 8ipb:la, 8jiw:BQ, 4v3p:SI, 4v7e:BQ
43 6v39:i 127 131 0.1446 0.3701 0.3588 7.44e-07 7m4u:i, 7m4w:i, 7m4x:i, 7m4y:i, 7m4z:i, 7ryf:i, 7ryg:i, 7ryh:i, 7uvv:i, 7uvw:i, 7uvx:i, 7uvy:i, 7uvz:i, 7uw1:i, 6v3a:i, 6v3b:i, 6v3e:i, 6ys5:j, 6ytf:j
44 7qep:C6 141 133 0.1138 0.2624 0.2782 4.99e-06
45 4bts:AI 143 133 0.1262 0.2867 0.3083 9.17e-06 4bts:BI, 4bts:CI, 4bts:DI, 4v5o:AI, 4v5o:BI
46 8fvy:Q 158 129 0.1292 0.2658 0.3256 4.67e-05 8br8:ST, 8brm:ST, 8bsi:ST, 8bsj:ST, 8btd:ST, 8btr:ST, 8g4s:Q, 7pwf:Q, 7pwo:Q1
47 8p5d:SQ0 142 141 0.1169 0.2676 0.2695 0.003 8p60:SQ0, 8p60:RQ0, 7qca:SQ0
48 6rm3:SQ0 152 142 0.1138 0.2434 0.2606 0.004
49 6zu5:SQ0 127 123 0.1108 0.2835 0.2927 0.023
50 6df1:H 220 35 0.0492 0.0727 0.4571 0.25 6df2:H, 6df2:B
51 6dwi:J 214 35 0.0431 0.0654 0.4000 2.2 6dwi:D, 6dwi:H, 6dwi:L
52 5hm1:A 119 41 0.0523 0.1429 0.4146 2.8 5hm1:B, 5hm1:C
53 2zad:A 344 158 0.1323 0.1250 0.2722 3.4 3deq:A, 3deq:B, 3deq:C, 3deq:D, 3der:A, 3der:B, 3der:C, 3der:D, 3des:A, 3des:B, 3des:C, 3des:D, 3dfy:A, 3dfy:B, 3dfy:C, 3dfy:D, 3dfy:E, 3dfy:F, 3dfy:G, 3dfy:H, 3dfy:I, 3dfy:J, 3dfy:K, 3dfy:L, 3dfy:M, 3dfy:N, 3dfy:O, 3dfy:P, 2zad:B, 2zad:C, 2zad:D
54 8e2l:C 461 36 0.0523 0.0369 0.4722 5.2 8e2l:A, 8e2l:B, 8e2l:D, 8e2l:E, 8e2l:F
55 2exr:A 491 45 0.0523 0.0346 0.3778 5.8 2q4w:A
56 4hs8:H 225 35 0.0431 0.0622 0.4000 6.8
57 5dm0:B 272 66 0.0615 0.0735 0.3030 7.6 5dly:A, 5dm0:A, 4kvz:A
58 8rda:H 222 35 0.0431 0.0631 0.4000 9.5 8rdf:H
59 1f4x:H 216 34 0.0431 0.0648 0.4118 9.6 1f4y:H
60 8fbw:C 231 35 0.0400 0.0563 0.3714 9.8 8fbw:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218