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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VHNDVTVPDFSAYRREDVMDATTSSQTSSEDRKGFSYLVTATACVATAYAAKNVVTQFISSLSASADVLALSKIEIKLSD
IPEGKNVAFKWRGKPLFVRHRTQAEINQEAEVDVSKLRDPQHDLDRVKKPEWVILVGVCTHLGCVPIANSGDFGGYYCPC
HGSHYDASGRIRKGPAPYNLEVPTYQFVGDDLVVVG

The query sequence (length=196) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3cwb:E 196 196 1.0000 1.0000 1.0000 7.43e-148 3cwb:R, 3h1h:E, 3h1h:R, 3h1i:R, 3h1i:E, 3h1j:R, 3h1j:E, 3h1k:E, 3h1k:R, 3h1l:E, 3h1l:R, 3l70:E, 3l70:R, 3l71:E, 3l71:R, 3l72:E, 3l72:R, 3l73:E, 3l73:R, 3l74:E, 3l74:R, 3l75:E, 3l75:R, 3tgu:E, 3tgu:R, 4u3f:E, 4u3f:R
2 2a06:E 196 195 0.8061 0.8061 0.8103 1.18e-118 2a06:R, 1bcc:E, 2bcc:E, 3bcc:E, 1be3:E, 1bgy:Q, 4d6t:R, 4d6u:R, 7dkf:Q1, 2fyu:E, 5gpn:E, 5gpn:Q, 5gup:2, 5gup:4, 6haw:E, 8iog:C, 8iog:c, 5j4z:AE, 5j4z:AP, 5j7y:AE, 5j7y:AP, 5j8k:AE, 5j8k:AP, 5klv:E, 1l0l:E, 1l0n:E, 5luf:q, 6nhg:E, 5nmi:E, 1ntk:E, 1ntm:E, 1ntz:E, 1nu1:E, 7o37:E, 7o37:P, 7o3c:E, 7o3c:P, 7o3h:E, 7o3h:P, 5okd:E, 8p65:E, 8p65:R, 1pp9:R, 1pp9:E, 1ppj:R, 1ppj:E, 8pw5:E, 8pw5:P, 8pw6:E, 8pw6:P, 8pw7:E, 8pw7:P, 6q9e:f1, 6q9e:f2, 6qbx:f1, 6qbx:f2, 6qc2:f1, 6qc2:f2, 6qc3:f1, 6qc3:f2, 6qc4:f1, 6qc4:f2, 7r3v:E, 1rie:A, 1sqb:E, 1sqp:E, 1sqq:E, 1sqv:E, 1sqx:E, 7tay:E, 7tz6:E, 7tz6:R, 8ugd:3E, 8ugd:3R, 8uge:3E, 8uge:3R, 8ugf:3E, 8ugf:3R, 8ugg:3E, 8ugg:3R, 8ugh:3E, 8ugh:3R, 8ugi:3E, 8ugi:3R, 8ugj:3E, 8ugj:3R, 8ugk:3E, 8ugk:3R, 8ugn:3E, 8ugn:3R, 8ugr:3E, 8ugr:3R, 8ugr:6E, 8ugr:6R, 5xte:C, 5xte:P, 5xth:AC, 5xth:AP, 5xti:AC, 5xti:AP, 6xvf:E, 2ybb:e, 2ybb:E, 6zfs:E, 6zft:E, 6zfu:E
3 7rja:C 181 187 0.5204 0.5635 0.5455 7.76e-80 7rja:M, 7rjb:E, 7rjc:E, 7rjd:E, 7rje:C, 7rje:M
4 8ab7:P 186 189 0.5153 0.5430 0.5344 3.66e-78 8ab7:E, 8ab8:P, 8ab9:P, 8aba:P, 8abb:P, 8abe:P, 8abf:P, 8abg:P, 8abh:P, 8abi:P, 8abj:P, 8abk:P, 8abm:P, 8ac3:P, 8ac4:P, 8ac5:P
5 8q1b:E 182 188 0.5102 0.5495 0.5319 1.88e-76 8q1b:P
6 3cx5:P 185 184 0.5102 0.5405 0.5435 2.12e-76 3cx5:E, 3cxh:P, 3cxh:E, 8e7s:C, 8e7s:c, 8ec0:C, 8ec0:c, 1ezv:E, 6giq:E, 6giq:P, 6hu9:E, 6hu9:P, 2ibz:E, 1kb9:E, 1kyo:E, 1kyo:P, 1p84:E, 4pd4:E, 6t0b:E, 6t0b:P, 6t15:E, 6t15:P, 6ymx:E, 6ymx:P
7 8bpx:AD 196 164 0.4541 0.4541 0.5427 1.61e-67 8bel:D, 8bel:N, 8bpx:BD, 8bq5:AD, 8bq5:BD, 8bq6:AD, 8bq6:BD
8 8iuf:QE 231 184 0.3878 0.3290 0.4130 3.04e-54 8iuf:Qe, 8iuj:QE, 8iuj:Qe
9 8ibd:AE 109 176 0.4745 0.8532 0.5284 3.10e-53 8ibg:AE
10 2yiu:F 174 153 0.3571 0.4023 0.4575 1.35e-47 2yiu:C
11 1zrt:E 183 184 0.3878 0.4153 0.4130 5.72e-47 6xi0:E, 6xi0:R, 6xkt:E, 6xkt:R, 6xku:E, 6xku:R, 6xkv:E, 6xkv:R, 6xkw:E, 6xkw:R, 6xkx:E, 6xkx:R, 6xkz:E, 6xkz:R, 1zrt:R
12 8asi:E 181 154 0.3418 0.3702 0.4351 3.29e-41 8asi:A, 8asj:A, 8asj:E, 2fyn:C, 2fyn:F, 2fyn:I, 2fyn:L, 2fyn:O, 2fyn:R, 5kkz:G, 5kkz:C, 5kkz:Q, 5kkz:M, 5kli:C, 5kli:G, 5kli:M, 5kli:Q, 6nhh:C, 6nhh:G, 6nin:C, 6nin:G, 6nin:M, 6nin:Q, 6nin:U, 6nin:Y, 2nuk:A, 2num:A, 2nve:A, 2nvf:A, 2nvg:A, 2nwf:A, 2qjk:C, 2qjk:F, 2qjk:I, 2qjk:L, 2qjk:O, 2qjk:R, 2qjp:F, 2qjp:C, 2qjp:L, 2qjp:I, 2qjy:F, 2qjy:C, 2qjy:L, 2qjy:I, 2qjy:R, 2qjy:O, 7tce:C, 7tce:G, 7tce:M, 7tce:Q, 7tlj:G, 7tlj:C
13 8smr:Z 194 180 0.3520 0.3557 0.3833 8.42e-32 8smr:C, 8snh:C, 8snh:Z
14 7yr9:A 146 143 0.2449 0.3288 0.3357 1.03e-22 7yr9:B, 7yra:A, 7yra:B
15 8b6j:E 245 108 0.2092 0.1673 0.3796 1.31e-21 8b6j:e, 8bqs:E, 8bqs:e, 8gym:qE, 8gym:qe, 8gym:QE, 8gym:Qe, 8gzu:qE, 8gzu:qe, 8gzu:QE, 8gzu:Qe, 7tgh:3E
16 3azc:A 133 60 0.1378 0.2030 0.4500 8.04e-11
17 4h44:D 166 96 0.1684 0.1988 0.3438 8.10e-11 4ogq:D, 2zt9:D
18 2d2c:D 168 58 0.1429 0.1667 0.4828 8.73e-11 2d2c:Q, 2e74:D, 2e75:D, 2e76:D, 4h0l:D, 4h13:D, 4i7z:D, 4pv1:D, 1vf5:D, 1vf5:Q
19 7r0w:D 169 45 0.1173 0.1361 0.5111 5.94e-10 7r0w:L, 7zxy:D, 7zxy:L
20 6rqf:L 179 45 0.1173 0.1285 0.5111 2.11e-09 7qrm:D, 7qrm:L, 1rfs:A, 6rqf:D, 7zyv:D, 7zyv:L
21 1q90:C 126 50 0.1276 0.1984 0.5000 5.80e-09
22 6kls:A 134 137 0.2092 0.3060 0.2993 6.43e-08 6kls:D, 6klv:A, 6klv:D
23 5cxm:A 99 93 0.1276 0.2525 0.2688 6.34e-07 5cxm:B, 5cxm:C, 5cxm:D
24 8hn2:A 110 45 0.1020 0.1818 0.4444 3.60e-05 8hn2:B
25 7e1v:A 378 98 0.1531 0.0794 0.3061 0.004 7e1v:M, 7e1w:M, 7e1w:A, 7e1x:M, 7e1x:A, 8hcr:A, 8hcr:M
26 3fou:A 156 29 0.0765 0.0962 0.5172 0.006 3fou:B, 1nyk:A, 1nyk:B
27 1jm1:A 202 115 0.1684 0.1634 0.2870 0.007
28 8cff:B 134 63 0.1122 0.1642 0.3492 0.016 8cff:D, 8cff:F, 8cff:H, 8cgs:B, 8cgs:D, 8cgs:F, 8cgs:H, 8ch9:B, 8ch9:D, 8ch9:F, 8ch9:H, 1g8k:B, 1g8k:D, 1g8k:F, 1g8k:H
29 1g8j:D 129 63 0.1071 0.1628 0.3333 0.050 1g8j:B
30 7qhm:A 402 41 0.0816 0.0398 0.3902 0.064 7q21:A, 7q21:a, 7qhm:N, 7qho:A, 7qho:N
31 8e73:E 74 41 0.0765 0.2027 0.3659 0.17 8e73:Q
32 6adq:A 382 98 0.1429 0.0733 0.2857 0.21 6adq:M, 6hwh:A, 6hwh:B, 8ovc:M, 8ovc:G, 8ovd:M, 8ovd:G, 7rh5:M, 7rh5:Y, 7rh6:M, 7rh6:Y, 7rh7:Y, 7rh7:M
33 7ygh:B 184 45 0.0918 0.0978 0.4000 1.1 7ygh:A, 7ygl:A, 7ygl:B, 7yhl:A, 7yhl:B
34 5j7o:F 622 86 0.1276 0.0402 0.2907 1.3 5j7o:A, 5j7o:B, 5j7o:C, 5j7o:D, 5j7o:E, 5j7u:A, 5j7u:B, 5j7u:C, 5j7u:D, 5j7u:E, 5j7u:F, 5j7u:G, 5j7u:H, 5j7u:I, 5j7u:J, 5j7u:K, 5j7u:L
35 7elb:A 1937 105 0.1684 0.0170 0.3143 2.2 7ckm:A, 7elb:C, 6kld:A, 6kle:A, 6klh:A, 6klh:C
36 8om5:A 828 47 0.0816 0.0193 0.3404 2.9 8omo:A
37 5lkm:B 346 41 0.0561 0.0318 0.2683 4.1
38 2bmo:A 437 42 0.0663 0.0297 0.3095 4.7 2bmq:A, 2bmr:A
39 8ag6:A 896 47 0.0816 0.0179 0.3404 5.2 2o8b:A, 2o8c:A, 2o8d:A, 2o8e:A, 2o8f:A, 8olx:A, 8om9:A, 8oma:A, 8omq:A, 3thw:A, 3thx:A, 3thy:A, 3thz:A
40 5lkm:A 390 41 0.0561 0.0282 0.2683 5.5 5lkm:C
41 5xbp:A 444 42 0.0663 0.0293 0.3095 7.4 5xbp:D, 5xbp:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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