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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VHHDGFQTVKATIDWEHPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDILPMAH
ALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNRLYADDSPEAVIRAATV
YNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEDERYYELFIRYMDELWPHVIGY
VDYLTELGKRQQQLARTYALEIDYDLLRHYVIKQFNLRKKQISRTK

The query sequence (length=286) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5dcs:A 287 286 1.0000 0.9965 1.0000 0.0 5dco:A, 5dcr:A, 5ekb:A, 6f65:A, 6f6b:A, 6f6c:A, 6f6c:B, 6f6e:A, 6f6e:B, 6f6f:A, 6f6g:A, 6f6g:B, 6f6h:A, 6f6h:B, 6f6k:A, 6f6k:B, 6f6l:A, 6f6l:B, 6f6m:A, 6f6m:B, 4hr0:A, 4hr4:A, 6i90:A, 6i92:A, 6i93:A, 6i94:A, 6i95:A, 5omj:A, 5omk:A, 6qjv:A, 6qk0:A, 6qk0:B, 6qk1:A, 6qk2:A, 6qk2:B, 4xb9:A, 4xbv:A, 4xbv:B, 4xbw:A
2 6qrz:A 274 263 0.3601 0.3759 0.3916 9.48e-57
3 7qbp:A 291 284 0.3566 0.3505 0.3592 1.91e-56
4 7qbk:A 284 275 0.3636 0.3662 0.3782 4.40e-56
5 4ac8:A 311 233 0.3322 0.3055 0.4077 6.47e-52 4ac8:B, 4ac8:C, 4ac8:D, 3ee4:A
6 5v4t:A 212 102 0.1119 0.1509 0.3137 1.41e-04 5v4t:B
7 3hf1:B 286 223 0.1818 0.1818 0.2332 2.94e-04 3hf1:A, 2vux:A
8 8dq5:B 265 210 0.1538 0.1660 0.2095 3.09e-04
9 7aik:A 321 279 0.2238 0.1994 0.2294 0.001 7ail:A, 7q39:AAA, 7q3c:AAA
10 6d9f:B 322 163 0.1434 0.1273 0.2515 0.002 6d9f:A
11 2rcc:C 311 195 0.1538 0.1415 0.2256 0.004 2rcc:B
12 6y2n:A 306 205 0.1503 0.1405 0.2098 0.005
13 2vux:B 255 104 0.0979 0.1098 0.2692 0.014
14 5olk:A 395 212 0.1573 0.1139 0.2123 0.022 5olk:B, 5olk:C, 5olk:D, 6sf5:A, 6sf5:B
15 2o1z:A 288 203 0.1853 0.1840 0.2611 0.025 2o1z:B, 2p1i:A, 2p1i:B, 2p1i:C, 2p1i:D, 2p1i:E, 2p1i:F, 2p1i:G, 2p1i:H
16 6cwq:A 308 227 0.1538 0.1429 0.1938 0.033 6cwo:A, 6cwo:B, 6cwp:B, 6cwp:A, 6cwq:B, 8dq4:A, 8dq4:B, 8dq5:A
17 8dq3:D 297 198 0.1503 0.1448 0.2172 0.050 8dq3:A, 8dq3:B, 8dq3:C
18 1h0n:A 288 212 0.1573 0.1562 0.2123 0.067 1h0o:A, 2uw2:A, 3vpm:A, 3vpm:B, 3vpn:A, 3vpn:B, 3vpo:A, 3vpo:B, 1w68:A, 1w69:A, 1xsm:A
19 6zjk:A 317 199 0.1608 0.1451 0.2312 1.7 6zjk:C, 6zjk:D, 6zjk:B
20 8wy4:A 451 67 0.0559 0.0355 0.2388 2.4 8wy4:B, 8wy4:D, 8wy4:C, 8wy5:A, 8wy5:B, 8wy5:C, 8wy5:D, 8x51:A, 8x51:B
21 8x5i:D 557 67 0.0559 0.0287 0.2388 2.6 8x5i:B
22 8x5i:A 477 67 0.0559 0.0335 0.2388 2.6 8x5i:C, 8x5n:A, 8x5n:D, 8x5n:B, 8x5n:C
23 7rk5:B 501 116 0.1049 0.0599 0.2586 3.3 7rk5:A
24 7mdi:E 353 23 0.0385 0.0312 0.4783 5.7 7mdi:G, 7mdi:F, 7mdi:H
25 6z5u:A 254 36 0.0455 0.0512 0.3611 6.2
26 1jk0:A 334 45 0.0490 0.0419 0.3111 8.9
27 7mq8:SM 290 94 0.0839 0.0828 0.2553 9.6 7mq9:SM, 7mqa:SM

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218