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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VGDLVIEESTYTARLKGRALELTYKEFELLKYLAQHAGRVFTRAQLLQEVWGYDFFGGTRTVDVHVRRLRAKLGPEYDSM
IGTVRNVGYKFVRPS

The query sequence (length=95) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hig:A 98 95 0.9684 0.9388 0.9684 2.91e-61 8hig:B, 8hml:A, 8hml:B
2 8hih:O 217 95 0.8526 0.3733 0.8526 1.14e-56 8hih:P, 8hih:N, 8hih:Q
3 6cqg:A 98 91 0.5158 0.5000 0.5385 7.53e-26
4 2oqr:A 226 83 0.4000 0.1681 0.4578 1.02e-20
5 2z33:A 104 89 0.3895 0.3558 0.4157 1.02e-18 1gxp:A, 1gxp:B, 1gxp:E, 1gxp:F
6 7e1b:A 209 90 0.4842 0.2201 0.5111 2.17e-17 7e1b:B, 7e1b:C, 7e1b:H, 7e1b:D, 7e1b:E, 7e1b:F, 7e1b:G, 7e1h:A, 7e1h:B, 7e1h:E
7 2gwr:A 225 96 0.4421 0.1867 0.4375 6.66e-17 3nhz:B, 3nhz:C, 3nhz:D
8 1ys6:B 227 93 0.4421 0.1850 0.4516 1.22e-16 1ys6:A, 1ys7:A, 1ys7:B
9 8uvx:A 222 95 0.3368 0.1441 0.3368 1.23e-12 8uvk:A, 8uvk:B, 8uvx:B
10 4b09:A 218 90 0.3684 0.1606 0.3889 1.32e-12 4b09:B, 4b09:C, 4b09:D, 4b09:E, 4b09:F, 4b09:G, 4b09:I, 4b09:K
11 5ed4:E 224 93 0.3263 0.1384 0.3333 1.61e-12 5ed4:A, 5ed4:B, 5ed4:F, 2pmu:E
12 4nhj:A 102 92 0.3684 0.3431 0.3804 4.85e-12 4nhj:B
13 5x5l:E 98 84 0.3053 0.2959 0.3452 5.56e-09 5x5l:B, 5x5l:H, 5x5l:A
14 8jo2:H 219 91 0.3474 0.1507 0.3626 9.62e-08 8jo2:I, 4s04:A, 4s04:B, 4s04:E, 4s04:F, 4s05:A, 4s05:B, 3w9s:A, 3w9s:B
15 5ju7:A 107 100 0.3263 0.2897 0.3100 2.99e-07
16 6lxn:A 110 76 0.2632 0.2273 0.3289 1.79e-06 6lxn:B
17 4kny:B 226 99 0.3263 0.1372 0.3131 2.19e-06 4kfc:A, 4kfc:B, 4kny:A, 1zh2:A, 1zh2:B, 1zh4:A, 1zh4:B
18 7lza:A 219 75 0.2737 0.1187 0.3467 1.33e-05 7lz9:A
19 1p6x:A 333 53 0.2105 0.0601 0.3774 0.054 1p6x:B, 1p72:A, 1p72:B, 1p73:A, 1p73:B, 1p73:C, 1p73:D, 1p75:A, 1p75:B, 1p75:C, 1p75:D
20 5cvi:B 215 37 0.1474 0.0651 0.3784 0.33 5cvi:A
21 1unf:X 214 47 0.1579 0.0701 0.3191 0.47
22 7d5s:RI 252 65 0.2000 0.0754 0.2923 1.7 7ajt:UZ, 6ke6:RI, 6lqp:RI, 6lqu:RI, 7suk:SN, 5wlc:SN, 5wyj:U5, 5wyk:U5, 5ydt:U5, 6zqa:UZ, 6zqb:UZ, 6zqc:UZ
23 8t2j:A 339 49 0.1474 0.0413 0.2857 2.5
24 8e73:G2 258 29 0.1158 0.0426 0.3793 3.4 6x89:G2
25 5zlu:d 176 21 0.1368 0.0739 0.6190 4.7 5a9z:AH, 5aa0:AH, 7azo:L6A, 7azo:L6B, 7azs:L6A, 7azs:L6B, 9b00:1H, 9b00:2H, 6b4v:I, 6b4v:MB, 6boh:I, 6boh:NB, 6bok:I, 6bok:LB, 6buw:RH, 6buw:YH, 6bz6:RH, 6bz6:YH, 6bz7:RH, 6bz7:YH, 6bz8:RH, 6bz8:YH, 6c5l:BH, 6c5l:DH, 6cae:1H, 6cae:2H, 6cfj:1H, 6cfj:2H, 6cfk:1H, 6cfk:2H, 6cfl:1H, 6cfl:2H, 8cvj:1H, 8cvj:2H, 8cvk:1H, 8cvk:2H, 8cvl:1H, 8cvl:2H, 5czp:YH, 5czp:RH, 6czr:1H, 6czr:2H, 5d8b:E, 5d8b:AB, 5dfe:YH, 5dfe:RH, 5dox:1H, 5dox:2H, 5doy:1H, 5doy:2H, 5e7k:51, 5e81:51, 8ekb:1H, 8ekb:2H, 5el4:51, 5el5:51, 5el6:51, 5el7:51, 8ev6:1H, 8ev6:2H, 8ev7:1H, 8ev7:2H, 5f8k:1H, 5f8k:2H, 8fc1:1H, 8fc1:2H, 8fc2:1H, 8fc2:2H, 8fc3:1H, 8fc3:2H, 8fc4:1H, 8fc4:2H, 8fc5:1H, 8fc5:2H, 8fc6:1H, 8fc6:2H, 5fdu:1H, 5fdu:2H, 5fdv:1H, 5fdv:2H, 6fkr:1H, 6fkr:2H, 8fom:RH, 8fom:YH, 8fon:RH, 8fon:YH, 8g29:1H, 8g29:2H, 8g2a:1H, 8g2a:2H, 8g2b:1H, 8g2b:2H, 8g2c:1H, 8g2c:2H, 8g2d:1H, 8g2d:2H, 6gsj:51, 6gsj:59, 6gsk:51, 6gsk:59, 6gsl:51, 6gsl:59, 6gzq:G1, 6gzx:G1, 6gzx:G2, 6gzz:G1, 6gzz:G2, 5hau:1H, 5hau:2H, 5hcp:1H, 5hcp:2H, 5hcq:1H, 5hcq:2H, 5hcr:1H, 5hcr:2H, 5hd1:1H, 5hd1:2H, 5ib7:51, 5ib7:59, 5ib8:51, 5ib8:59, 5ibb:51, 5ibb:59, 5imq:e, 5imr:e, 5j30:RH, 5j30:YH, 5j3c:RH, 5j3c:YH, 5j4b:1H, 5j4b:2H, 5j4c:1H, 5j4c:2H, 5j4d:I, 5j4d:NB, 5j8b:H, 7jql:1H, 7jql:2H, 7jqm:1H, 7jqm:2H, 4l47:RH, 4l47:YH, 4l71:RH, 4l71:YH, 4lel:RH, 4lel:YH, 4lfz:RH, 4lfz:YH, 7lh5:BH, 7lh5:DH, 4lnt:RH, 4lnt:YH, 4lsk:RH, 4lsk:YH, 4lt8:RH, 4lt8:YH, 7md7:1H, 7md7:2H, 6n1d:AL06, 6n1d:BL06, 6n9e:1H, 6n9e:2H, 6n9f:1H, 6n9f:2H, 5ndj:51, 5ndj:59, 5ndk:51, 5ndk:59, 6nd5:1H, 6nd5:2H, 6nd6:1H, 6nd6:2H, 6ndk:RH, 6ndk:YH, 6nsh:RH, 6nsh:YH, 6nta:RH, 6nta:YH, 6nuo:RH, 6nuo:YH, 6nwy:RH, 6nwy:YH, 6o3m:RH, 6o3m:YH, 6o97:1H, 6o97:2H, 6of1:1H, 6of1:2H, 6of6:RH, 6of6:YH, 6oj2:RH, 6oj2:YH, 6ope:RH, 6ope:YH, 6ord:RH, 6ord:YH, 6osi:RH, 6osi:YH, 5ot7:k, 6otr:RH, 6otr:YH, 6oxa:RH, 6oxa:YH, 6oxi:RH, 6oxi:YH, 4p6f:RH, 4p6f:YH, 4p70:RH, 4p70:YH, 6q95:F, 6qnq:51, 6qnq:59, 6qnr:51, 6qnr:59, 7rq8:1H, 7rq8:2H, 7rq9:1H, 7rq9:2H, 7rqa:1H, 7rqa:2H, 7rqb:1H, 7rqb:2H, 7rqc:1H, 7rqc:2H, 7rqd:1H, 7rqd:2H, 7rqe:1H, 7rqe:2H, 8t8b:1H, 8t8b:2H, 8t8c:1H, 8t8c:2H, 4tua:RH, 4tua:YH, 4tub:RH, 4tub:YH, 4tuc:RH, 4tuc:YH, 4tud:RH, 4tud:YH, 4tue:RH, 4tue:YH, 7u2h:1H, 7u2h:2H, 7u2i:1H, 7u2i:2H, 7u2j:1H, 7u2j:2H, 6ucq:1H, 6ucq:2H, 8ud6:1H, 8ud6:2H, 8ud7:1H, 8ud7:2H, 8ud8:1H, 8ud8:2H, 6uo1:1H, 6uo1:2H, 5uq7:H, 5uq8:H, 8uvr:1H, 8uvr:2H, 8uvs:1H, 8uvs:2H, 4v4i:F, 4v4j:F, 4v4x:BH, 4v4y:BH, 4v4z:BH, 4v51:BH, 4v51:DH, 4v5a:BH, 4v5a:DH, 4v5c:BH, 4v5c:DH, 4v5d:BH, 4v5d:DH, 4v5e:BH, 4v5e:DH, 4v5f:BH, 4v5f:DH, 4v5g:BH, 4v5g:DH, 4v5j:BH, 4v5j:DH, 4v5k:BH, 4v5k:DH, 4v5l:BH, 4v5m:BH, 4v5n:BH, 4v5p:BH, 4v5p:DH, 4v5q:BH, 4v5q:DH, 4v5r:BH, 4v5r:DH, 4v5s:BH, 4v5s:DH, 4v63:BH, 4v63:DH, 4v67:BH, 4v67:DH, 4v68:BH, 4v6a:BH, 4v6a:DH, 4v6f:AH, 4v6f:DH, 4v6g:BH, 4v6g:DH, 4v7j:AH, 4v7j:BH, 4v7k:AH, 4v7k:BH, 4v7l:BH, 4v7l:DH, 4v7m:BH, 4v7m:DH, 4v7p:BG, 4v7p:CG, 4v7w:BH, 4v7w:DH, 4v7x:BH, 4v7x:DH, 4v7y:BH, 4v7y:DH, 4v7z:BH, 4v7z:DH, 4v83:BG, 4v83:DG, 4v84:BG, 4v84:DG, 4v87:AH, 4v87:DH, 4v8a:AH, 4v8a:BH, 4v8b:BH, 4v8b:DH, 4v8c:AH, 4v8c:BH, 4v8d:BH, 4v8d:DH, 4v8e:AH, 4v8e:CH, 4v8f:AH, 4v8f:DH, 4v8g:BH, 4v8g:DH, 4v8h:BH, 4v8h:DH, 4v8i:BH, 4v8i:DH, 4v8j:BH, 4v8j:DH, 4v8n:BH, 4v8n:DH, 4v8o:BH, 4v8q:AH, 4v8u:BH, 4v8u:DH, 4v8x:BH, 4v8x:DH, 5v8i:1H, 5v8i:2H, 4v90:BH, 4v95:BH, 4v95:DH, 4v97:BH, 4v97:DH, 4v9a:BH, 4v9a:DH, 4v9b:BH, 4v9b:DH, 4v9h:BH, 4v9i:BH, 4v9i:DH, 4v9j:BH, 4v9j:DH, 4v9k:BH, 4v9k:DH, 4v9l:BH, 4v9l:DH, 4v9m:BH, 4v9m:DH, 4v9n:BH, 4v9n:DH, 4v9q:AH, 4v9q:CH, 4v9r:BH, 4v9r:DH, 4v9s:BH, 4v9s:DH, 5vp2:1H, 5vp2:2H, 5vpo:RH, 5vpo:YH, 5vpp:RH, 5vpp:YH, 8vtu:1H, 8vtu:2H, 8vtv:1H, 8vtv:2H, 8vtw:1H, 8vtw:2H, 8vtx:1H, 8vtx:2H, 8vty:1H, 8vty:2H, 1vvj:RH, 1vvj:YH, 1vy4:BH, 1vy4:DH, 1vy5:BH, 1vy5:DH, 1vy6:BH, 1vy6:DH, 1vy7:BH, 1vy7:DH, 4w29:BH, 4w29:DH, 4w2e:H, 4w2f:BH, 4w2f:DH, 4w2g:BH, 4w2g:DH, 4w2h:BH, 4w2h:DH, 4w2i:BH, 4w2i:DH, 4w4g:RH, 4w4g:YH, 5w4k:1H, 5w4k:2H, 5wis:1H, 5wis:2H, 5wit:1H, 5wit:2H, 4wpo:AH, 4wpo:CH, 4wq1:51, 4wq1:59, 4wqf:AH, 4wqf:CH, 4wqr:51, 4wqr:59, 4wqu:AH, 4wqu:CH, 4wqy:AH, 4wqy:CH, 4wr6:51, 4wr6:59, 4wra:51, 4wra:59, 4wro:51, 4wsd:51, 4wsd:59, 4wsm:51, 4wsm:59, 4wt1:51, 4wt1:59, 4wt8:CF, 4wt8:DF, 4wu1:51, 4wu1:59, 4wzd:51, 4wzd:59, 4wzo:51, 4wzo:59, 4xej:AL06, 4xej:BL06, 6xhv:1H, 6xhv:2H, 6xhw:1H, 6xhw:2H, 6xhx:1H, 6xhx:2H, 6xhy:1H, 6xhy:2H, 6xqd:1H, 6xqd:2H, 6xqe:1H, 6xqe:2H, 4y4o:1H, 4y4o:2H, 4y4p:1H, 4y4p:2H, 4ypb:RH, 4ypb:YH, 4yzv:RH, 4yzv:YH, 4z3s:1H, 4z3s:2H, 4z8c:1H, 4z8c:2H, 4zer:1H, 4zer:2H, 4zsn:RH, 4zsn:YH
26 5hnf:A 280 26 0.1053 0.0357 0.3846 8.3 5hlt:B, 5hlt:A, 5hnh:A, 2vla:A
27 3dz8:A 178 31 0.1158 0.0618 0.3548 8.7 8a4b:B, 8a4b:D, 8a4c:B, 8a4c:D
28 8cdu:C 708 89 0.2421 0.0325 0.2584 9.1 8cec:C, 8ced:C, 8cee:C
29 4e51:A 415 29 0.1368 0.0313 0.4483 9.3 4e51:B
30 6fmr:A 475 22 0.1053 0.0211 0.4545 9.6 4d2b:A, 4d2d:A, 5d58:A, 5d59:A, 6eia:A, 6fmy:A, 6ghj:A, 5oxl:A, 5oxm:A, 5oxn:A, 5oxo:A, 5oxq:A, 4xnj:A, 6yof:A, 6yog:A
31 5oxp:A 462 22 0.1053 0.0216 0.4545 9.7 7ac6:A, 4d2c:A, 5d6k:A, 5oxk:A, 4xni:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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