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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VEVLSVVTGEDSITQIELYLNPRMGVNSPDLPTTSNWYTYTYDLQPKGSSPDQPIKENLPAYSVARVSLPMLNTLQMWEA
ISVKTEVVGISSLINVHYWDMKRVHDYGAGIPVSGVNYHMFAIGGEPLDLQGLVLDYQTQYPKTGPITIETVLGRKMTPK
NQGLDPQAKAKLDKDGNYPIEVWCPDPSKNENSRYYGSIQTGSQTPTVLQFSNTLTTVLLDENGVGPLCKGDGLFISCAD
IVGFLFKTSGKMALHGLPRYFNVTLRKRWVK

The query sequence (length=271) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6zlz:B 371 280 1.0000 0.7305 0.9679 0.0 4fmh:B, 4fmh:H, 4fmh:K, 4fmh:M, 4fmh:O, 4fmh:Q, 4fmh:T, 4fmi:A, 4fmi:T, 4fmi:E, 4fmi:M, 4fmj:K, 4fmj:M, 4fmj:O, 4fmj:Q, 4fmj:S, 4fmj:T, 4fmj:H, 6zlz:A, 6zlz:C, 6zlz:D, 6zlz:E, 6zlz:F
2 4mby:A 277 279 0.6015 0.5884 0.5842 1.96e-104 4mby:B, 4mby:C, 4mby:D, 4mby:E, 4mby:G, 4mby:I, 4mby:H, 4mby:J, 4mby:F, 4mbz:B, 4mbz:A, 4mbz:C, 4mbz:E, 4mbz:D, 4mbz:I, 4mbz:H, 4mbz:J, 4mbz:F
3 4u60:C 274 278 0.5720 0.5657 0.5576 3.53e-104 6hku:B, 6hku:C, 6hku:F, 6hku:I, 6hku:J, 6hku:D, 6hkv:A, 6hkv:B, 6hkv:C, 6hkv:D, 6hkv:E, 6hkv:F, 6hkv:G, 6hkv:H, 6hkv:I, 6hkv:J, 4u60:A, 4u60:D, 4u60:E, 4u60:B, 4u61:A, 4u61:B, 4u61:C, 4u61:E, 4u61:H, 4u61:I, 4u61:J, 4u62:B, 4u62:C, 4u62:J
4 4pos:J 274 279 0.6052 0.5985 0.5878 2.79e-101 4por:B, 4por:A, 4por:C, 4por:D, 4por:E, 4por:F, 4por:H, 4por:G, 4por:I, 4por:J, 4pos:B, 4pos:A, 4pos:C, 4pos:E, 4pos:D, 4pos:G, 4pos:F, 4pos:H, 4pos:I, 4pot:B, 4pot:A, 4pot:C, 4pot:D, 4pot:E, 4pot:G, 4pot:F, 4pot:H, 4pot:I, 4pot:J
5 6y9i:CCC 280 281 0.5720 0.5536 0.5516 2.05e-98
6 1sid:B 367 287 0.5646 0.4169 0.5331 4.92e-97 1cn3:A, 1cn3:B, 1cn3:D, 1cn3:E, 5cpw:A, 5cpw:B, 5cpw:C, 5cpw:D, 5cpw:E, 5cpx:A, 5cpx:B, 5cpx:C, 5cpx:D, 5cpx:E, 5cpy:A, 5cpy:B, 5cpy:C, 5cpy:D, 5cpy:E, 5cpz:A, 5cpz:B, 5cpz:C, 5cpz:D, 5cpz:E, 5cq0:A, 5cq0:B, 5cq0:C, 5cq0:D, 5cq0:E, 1sid:A, 1sid:C, 1sid:D, 1sid:E, 1sid:F, 1sie:A, 1sie:B, 1sie:C, 1sie:D, 1sie:E, 1sie:F, 1vps:A, 1vps:B, 1vps:C, 1vps:D, 1vps:E
7 6y5y:D 285 285 0.5720 0.5439 0.5439 2.72e-96 6y5x:A, 6y5x:C, 6y5x:D, 6y5x:E, 6y5x:I, 6y5y:A, 6y5y:B, 6y5y:C, 6y5y:E, 6y5y:F, 6y5y:G, 6y5y:H, 6y5y:I, 6y5y:J
8 6y66:GGG 268 278 0.5461 0.5522 0.5324 1.21e-95 6y66:AAA, 6y66:BBB, 6y66:CCC, 6y66:DDD, 6y66:EEE, 6y66:FFF, 6y66:HHH, 6y66:III, 6y66:JJJ
9 6y60:AAA 260 268 0.5572 0.5808 0.5634 8.66e-95 6y60:DDD, 6y60:EEE, 6y60:FFF, 6y60:HHH, 6y60:III, 6y60:JJJ, 6y60:BBB, 6y60:CCC, 6y60:GGG
10 6y6a:M 269 281 0.5535 0.5576 0.5338 3.22e-94 6y6a:A, 6y6a:B, 6y6a:C, 6y6a:E, 6y6a:F, 6y6a:G, 6y6a:I, 6y6a:J, 6y6a:K, 6y6a:L, 6y6a:N, 6y6a:O, 6y6a:Q, 6y6a:R, 6y6a:S, 6y6a:T, 6y6a:V, 6y6a:X, 6y6a:Y, 6y6a:Z, 6y6a:a, 6y6a:b, 6y6a:c, 6y6a:d, 6y6a:e, 6y6a:f, 6y6a:j, 6y6a:n
11 7b6s:FFF 271 281 0.5387 0.5387 0.5196 1.32e-92 7b6s:AAA, 7b6s:BBB, 7b6s:CCC, 7b6s:DDD, 7b6s:EEE, 7b6s:GGG, 7b6s:HHH, 7b6s:III, 7b6s:JJJ, 7b6t:AAA, 7b6t:CCC, 7b6t:DDD, 7b6t:FFF, 7b6t:HHH, 7b6t:JJJ, 7b6t:GGG, 7b6t:III, 7b6u:AAA, 7b6u:BBB, 7b6u:CCC, 7b6u:DDD, 7b6u:EEE, 7b6u:FFF, 7b6u:GGG, 7b6u:HHH, 7b6u:III, 7b6u:JJJ, 7b6v:AAA, 7b6v:BBB, 7b6v:CCC, 7b6v:DDD, 7b6v:EEE, 7b6v:FFF, 7b6v:GGG, 7b6v:HHH, 7b6v:III, 7b6v:JJJ, 6y63:AAA, 6y63:BBB, 6y63:HHH, 6y63:III, 6y63:EEE, 6y63:DDD, 6y63:GGG, 6y64:D, 6y64:F, 6y64:G, 6y64:J, 6y64:B, 6y64:A, 6y64:C, 6y64:E, 6y64:H, 6y64:I
12 3bwr:A 267 277 0.4945 0.5019 0.4838 4.63e-88 3bwr:C, 3bwr:E
13 6esb:1 347 278 0.4797 0.3746 0.4676 7.21e-84 7b6a:AAA, 7b6a:EEE, 7b6a:BBB, 7b6a:CCC, 7b6c:DDD, 7b6c:EEE, 7b6c:III, 7b6c:JJJ, 6esb:6, 6esb:2, 6esb:3, 6esb:4, 6esb:5, 4mj0:A, 4mj0:B, 4mj0:C, 4mj0:D, 7zip:DDD, 7ziq:AAA, 7ziq:BBB, 7ziq:DDD
14 7zim:CCC 265 277 0.4686 0.4792 0.4585 1.68e-80 4jcf:C, 3nxd:C, 3nxd:B, 4x0z:B, 4x0z:C, 4x0z:D, 4x10:B, 4x10:C, 4x10:D, 4x11:B, 4x11:E, 4x11:A, 4x12:A, 4x12:B, 4x12:E, 4x13:B, 4x13:C, 4x13:E, 4x14:B, 4x14:C, 4x14:D, 4x15:B, 4x15:C, 4x15:D, 4x16:B, 4x16:C, 4x16:D, 4x17:C, 4x17:D, 4x17:B, 7zil:BBB, 7zil:CCC, 7zil:DDD, 7zim:BBB, 7zim:DDD, 7zin:BBB, 7zin:CCC, 7zin:DDD, 7zio:BBB, 7zio:CCC, 7zio:DDD
15 4tpg:A 459 52 0.0590 0.0349 0.3077 0.32 4lep:A, 4lep:B, 4tph:A, 4tpj:B, 4tpj:A
16 1jfk:A 134 89 0.0959 0.1940 0.2921 0.92 3li6:A, 3li6:D, 3li6:G, 3li6:J, 2m7m:A, 2m7n:A, 2nxq:A, 2nxq:B, 3ulg:A, 3ulg:B, 5xop:A, 5xop:B, 5xop:C, 5xop:D, 5xop:E, 5xop:F
17 6o9n:A 613 97 0.1107 0.0489 0.3093 2.7 6o9n:B
18 7azq:A 199 42 0.0517 0.0704 0.3333 2.8 7azq:E, 7azr:A, 7azr:E
19 8w1o:K 1290 32 0.0406 0.0085 0.3438 3.1
20 4nf2:A 307 84 0.0627 0.0554 0.2024 5.2 4nf2:B, 4nf2:C
21 8fcy:A 2864 82 0.0849 0.0080 0.2805 6.9 8fd6:A, 8fdt:A
22 8pqw:A 2892 82 0.0849 0.0080 0.2805 7.0 8pqy:A, 8pqz:A, 8pqz:J
23 5nug:A 2920 82 0.0849 0.0079 0.2805 7.4 5nug:B
24 7z8g:A 3047 82 0.0849 0.0075 0.2805 7.5 8fdu:A, 7z8l:f

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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