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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VETPPEVVDFMVSLAEAPRGGRVLEPACAHGPFLRAFREAHGTGYRFVGVEIDPKALDLPPWAEGILADFLLWEPGEAFD
LILGNPPYGIVGEASKYPIHVFKAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLLKPGGVLVFVVPATWLVLEDFALLREF
LAREGKTSVYYLGEVFPQKKVSAVVIRFQKSGKGLSLWDTQESESGFTPILWAEYPHWEGEIIRFETEETRKLEISGMPL
GDLFHIRFAARSPEFKKHPAVRKEPGPGLVPVLTGRNLKPGWVDYEKNHSGLWMPKERAKELRDFYATPHLVVAHTKGTR
VVAAWDERAYPWREEFHLLPKEGVRLDPSSLVQWLNSEAMQKHVRTLYRDFVPHLTLRMLERLPVRREYGFHT

The query sequence (length=393) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2np6:A 394 393 0.9975 0.9949 0.9975 0.0 2adm:A, 2adm:B, 1aqi:A, 1aqi:B, 1aqj:A, 1aqj:B, 1g38:A, 1g38:D, 2ibs:A, 2ibs:D, 2ibt:A, 2ibt:D, 2ih2:A, 2ih2:D, 2ih4:A, 2ih4:D, 2ih5:A, 2jg3:A, 2jg3:D, 2np6:D, 2np7:A
2 7qw6:A 556 160 0.1094 0.0773 0.2687 2.00e-08 7qw5:A, 7qw7:A
3 7lt5:B 576 243 0.1476 0.1007 0.2387 1.65e-04 8cxs:A, 8cxs:B, 8cxs:C, 8cxt:A, 8cxt:B, 8cxt:C, 8cxu:A, 8cxu:B, 8cxu:C, 8cxv:A, 8cxv:B, 8cxv:C, 8cxw:A, 8cxw:B, 8cxw:C, 8cxx:A, 8cxx:B, 8cxx:C, 8cxy:A, 8cxy:B, 8cxy:C, 8cxz:A, 8cxz:B, 8cxz:C, 8cy0:A, 8cy0:B, 8cy0:C, 8cy1:A, 8cy1:B, 8cy1:C, 8cy2:A, 8cy2:B, 8cy2:C, 8cy3:A, 8cy3:B, 8cy3:C, 8cy4:A, 8cy4:B, 8cy4:C, 8cy5:A, 8cy5:B, 8cy5:C, 8fs1:A, 8fs1:B, 8fs1:C, 8fs2:A, 8fs2:B, 8fs2:C, 7lni:A, 7lni:B, 7lni:C, 7lnj:A, 7lnj:B, 7lnj:C, 7lt5:A, 7lt5:C, 7rfk:A, 7rfk:B, 7rfk:C, 7rfl:A, 7rfl:B, 7rfl:C, 7rfm:A, 7rfm:B, 7rfm:C, 7rfn:A, 7rfn:B, 7rfn:C, 8vpg:A, 8vpg:B, 8vpg:C, 8vph:A, 8vph:B, 8vph:C, 8vpi:A, 8vpi:B, 8vpi:C
4 2f8l:A 323 189 0.1094 0.1331 0.2275 0.003
5 2okc:B 426 221 0.1425 0.1315 0.2534 0.011 2okc:A
6 8c45:A 1218 90 0.0662 0.0213 0.2889 0.014 8c45:B, 8q56:A
7 3tm5:A 368 135 0.0992 0.1060 0.2889 0.019 3tlj:A, 3tlj:B, 3tm4:A, 3tm4:B, 3tm5:B
8 7eew:A 610 296 0.1705 0.1098 0.2264 0.056
9 8bpl:A 316 71 0.0662 0.0823 0.3662 0.30
10 7vru:A 497 110 0.0738 0.0584 0.2636 0.31 7vs4:A
11 5b1s:A 294 51 0.0458 0.0612 0.3529 0.37 5b1s:B, 5b1s:C, 5b1s:D, 3bwc:A, 3bwc:B, 5y4p:A, 5y4p:B, 5y4p:C, 5y4p:D, 5y4q:A, 5y4q:B, 5y4q:C, 5y4q:D, 4yuv:A, 4yuv:B, 4yuw:A, 4yuw:B, 4yux:A, 4yux:B, 4yuy:A, 4yuy:B, 4yuz:A, 4yuz:B, 4yuz:C, 4yuz:D, 4yv0:A, 4yv0:B, 4yv0:C, 4yv0:D, 4yv1:A, 4yv1:B, 4yv1:C, 4yv1:D, 4yv2:A, 4yv2:B
12 5bxy:A 155 85 0.0712 0.1806 0.3294 0.55 5bxy:B
13 4qdg:B 302 58 0.0483 0.0629 0.3276 0.64 4qdg:A
14 9c3s:A 250 53 0.0534 0.0840 0.3962 0.80 9c3s:B, 9c3s:C, 9c3s:D, 9c3t:A, 9c3t:B, 9c3t:C, 9c3t:D, 9c3u:A, 9c3u:B, 9c3u:C, 9c3u:D, 8urk:A, 8urk:B, 8urk:C, 8urk:D
15 5z3g:Y 438 205 0.1094 0.0982 0.2098 2.5 6c0f:p, 6cb1:p, 8e5t:p, 7nac:D, 7ohr:D, 7ohs:D, 7ohv:D, 7ohw:D, 7ohx:D, 7r6q:D, 7r7a:D, 8v87:D
16 5e1z:B 169 46 0.0433 0.1006 0.3696 3.9 5e1x:A, 5e20:A
17 7c9k:B 233 29 0.0305 0.0515 0.4138 5.7 7c9k:A
18 7c9m:C 260 29 0.0305 0.0462 0.4138 7.0 7c7m:A, 7c9m:A, 7c9m:B, 7c9m:D
19 5j92:B 259 46 0.0407 0.0618 0.3478 8.4 5j92:A, 5j92:C, 5j92:D
20 1np6:B 169 110 0.0687 0.1598 0.2455 9.3
21 3orh:A 230 49 0.0407 0.0696 0.3265 9.6 3orh:B, 3orh:C, 3orh:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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