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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VETPPEVVDFMVSLAEAPRGGRVLEPACAHGPFLRAFREAHGTGYRFVGVEIDPKALDLPPWAEGILADFLLWEPGEAFD
LILGNPPYGIVAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLLKPGGVLVFVVPATWLVLEDFALLREFLAREGKTSVYYL
GEVFPQKKVSAVVIRFQKSGKGLSLWDTQESESGFTPILWAEYPHWEGEIIRFETEETRKLEISGMPLGDLFHIRFAARS
PEFKKHPAVRKEPGPGLVPVLTGRNLKPGWVDYEKNHSGLWMPKERAKELRDFYATPHLVVAHTKGTRVVAAWDERAYPW
REEFHLLPKEGVRLDPSSLVQWLNSEAMQKHVRTLYRDFVPHLTLRMLERLPVRREYGFHT

The query sequence (length=381) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2np6:A 394 393 0.9974 0.9645 0.9669 0.0 2adm:A, 2adm:B, 1aqi:A, 1aqi:B, 1aqj:A, 1aqj:B, 1g38:A, 1g38:D, 2ibs:A, 2ibs:D, 2ibt:A, 2ibt:D, 2ih2:A, 2ih2:D, 2ih4:A, 2ih4:D, 2ih5:A, 2jg3:A, 2jg3:D, 2np6:D, 2np7:A
2 7qw6:A 556 154 0.1155 0.0791 0.2857 5.51e-09 7qw5:A, 7qw7:A
3 7lt5:B 576 237 0.1549 0.1024 0.2489 6.08e-05 8cxs:A, 8cxs:B, 8cxs:C, 8cxt:A, 8cxt:B, 8cxt:C, 8cxu:A, 8cxu:B, 8cxu:C, 8cxv:A, 8cxv:B, 8cxv:C, 8cxw:A, 8cxw:B, 8cxw:C, 8cxx:A, 8cxx:B, 8cxx:C, 8cxy:A, 8cxy:B, 8cxy:C, 8cxz:A, 8cxz:B, 8cxz:C, 8cy0:A, 8cy0:B, 8cy0:C, 8cy1:A, 8cy1:B, 8cy1:C, 8cy2:A, 8cy2:B, 8cy2:C, 8cy3:A, 8cy3:B, 8cy3:C, 8cy4:A, 8cy4:B, 8cy4:C, 8cy5:A, 8cy5:B, 8cy5:C, 8fs1:A, 8fs1:B, 8fs1:C, 8fs2:A, 8fs2:B, 8fs2:C, 7lni:A, 7lni:B, 7lni:C, 7lnj:A, 7lnj:B, 7lnj:C, 7lt5:A, 7lt5:C, 7rfk:A, 7rfk:B, 7rfk:C, 7rfl:A, 7rfl:B, 7rfl:C, 7rfm:A, 7rfm:B, 7rfm:C, 7rfn:A, 7rfn:B, 7rfn:C, 8vpg:A, 8vpg:B, 8vpg:C, 8vph:A, 8vph:B, 8vph:C, 8vpi:A, 8vpi:B, 8vpi:C
4 2f8l:A 323 177 0.1076 0.1269 0.2316 7.26e-04
5 2okc:B 426 211 0.1444 0.1291 0.2607 0.001 2okc:A
6 8c45:A 1218 82 0.0630 0.0197 0.2927 0.007 8c45:B, 8q56:A
7 3tm5:A 368 127 0.0971 0.1005 0.2913 0.011 3tlj:A, 3tlj:B, 3tm4:A, 3tm4:B, 3tm5:B
8 5b1s:A 294 165 0.1129 0.1463 0.2606 0.13 5b1s:B, 5b1s:C, 5b1s:D, 3bwc:A, 3bwc:B, 5y4p:A, 5y4p:B, 5y4p:C, 5y4p:D, 5y4q:A, 5y4q:B, 5y4q:C, 5y4q:D, 4yuv:A, 4yuv:B, 4yuw:A, 4yuw:B, 4yux:A, 4yux:B, 4yuy:A, 4yuy:B, 4yuz:A, 4yuz:B, 4yuz:C, 4yuz:D, 4yv0:A, 4yv0:B, 4yv0:C, 4yv0:D, 4yv1:A, 4yv1:B, 4yv1:C, 4yv1:D, 4yv2:A, 4yv2:B
9 7vru:A 497 159 0.0997 0.0765 0.2390 0.25 7vs4:A
10 5ybb:A 487 214 0.1391 0.1088 0.2477 0.43 5ybb:B
11 2cww:B 382 57 0.0551 0.0550 0.3684 0.45 2cww:A
12 5bxy:A 155 85 0.0735 0.1806 0.3294 0.53 5bxy:B
13 4qdg:B 302 58 0.0499 0.0629 0.3276 0.65 4qdg:A
14 9c3s:A 250 53 0.0551 0.0840 0.3962 0.78 9c3s:B, 9c3s:C, 9c3s:D, 9c3t:A, 9c3t:B, 9c3t:C, 9c3t:D, 9c3u:A, 9c3u:B, 9c3u:C, 9c3u:D, 8urk:A, 8urk:B, 8urk:C, 8urk:D
15 4ylf:B 468 107 0.0761 0.0620 0.2710 3.1 4ylf:D, 4yry:B, 4yry:D
16 5z3g:Y 438 205 0.1129 0.0982 0.2098 3.1 6c0f:p, 6cb1:p, 8e5t:p, 7nac:D, 7ohr:D, 7ohs:D, 7ohv:D, 7ohw:D, 7ohx:D, 7r6q:D, 7r7a:D, 8v87:D
17 5e1z:B 169 46 0.0446 0.1006 0.3696 3.7 5e1x:A, 5e20:A
18 7c9k:B 233 29 0.0315 0.0515 0.4138 5.7 7c9k:A
19 7c9m:C 260 29 0.0315 0.0462 0.4138 7.1 7c7m:A, 7c9m:A, 7c9m:B, 7c9m:D
20 5j92:B 259 46 0.0420 0.0618 0.3478 8.8 5j92:A, 5j92:C, 5j92:D
21 1np6:B 169 110 0.0709 0.1598 0.2455 8.9
22 3orh:A 230 42 0.0394 0.0652 0.3571 9.8 3orh:B, 3orh:C, 3orh:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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