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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VEPVVVIDGKGHLVGRLASVVAKQLLNGQKIVVVRAEELNISGEFFRNKLKYHDFLRFRAPSRIFYKALRGMVSHKTARG
KAALERLKVFEGIPPPYDKKKRVVVPQALRVLRLKPGRKYTTLGKLSTSVGWKYEDVVAKLEAKRKVSSAEYYAKKRAFT
KKVASANATAAESDVAKQLAALGY

The query sequence (length=184) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v6i:BK 199 197 1.0000 0.9246 0.9340 8.02e-128 8aaf:B, 8agt:B, 8agu:B, 8agv:B, 8agw:B, 8agx:B, 8agz:B, 5apn:O, 5apo:O, 7azy:V, 7b7d:LQ, 8bip:LO, 8bjq:LO, 8bn3:M6, 8bqd:AU, 8bqx:AU, 7bt6:O, 7btb:O, 6c0f:O, 6cb1:O, 8ccs:A, 8cdl:A, 8cdr:A, 8ceh:A, 8cf5:A, 8cg8:A, 8cgn:A, 8civ:A, 8cku:A, 8cmj:A, 5dat:M6, 5dat:m6, 5dc3:M6, 5dc3:m6, 5dge:M6, 5dge:m6, 5dgf:M6, 5dgf:m6, 5dgv:M6, 5dgv:m6, 8e5t:O, 6elz:O, 6em1:O, 6em3:O, 6em4:O, 6em5:O, 8eub:AO, 8evp:AO, 8evq:AO, 8evr:AO, 8evs:AO, 8evt:AO, 8ewb:AO, 8ewc:AO, 5fci:M6, 5fci:m6, 5fcj:M6, 5fcj:m6, 6ft6:O, 5gak:Q, 6gq1:O, 6gqb:O, 6gqv:O, 5h4p:O, 6hd7:Q, 8hfr:O6, 6hhq:w, 6hhq:CQ, 5i4l:M6, 5i4l:m6, 6i7o:AU, 6i7o:XU, 3j6x:56, 3j6y:56, 3j77:66, 3j78:66, 3jct:O, 5jcs:O, 5juo:T, 5jup:T, 5jus:T, 5jut:T, 5juu:T, 8k2d:LO, 8k82:LO, 5lyb:M6, 5lyb:m6, 5m1j:K5, 6m62:O, 5mc6:AU, 5mei:w, 5mei:CQ, 7mpi:AO, 7mpj:AO, 6n8j:O, 6n8k:O, 6n8l:O, 6n8m:b, 6n8n:b, 6n8o:b, 7n8b:AO, 7nac:O, 5ndg:M6, 5ndg:m6, 5ndv:M6, 5ndv:m6, 5ndw:M6, 5ndw:m6, 7nrc:LQ, 7nrd:LQ, 5obm:M6, 5obm:m6, 7of1:O, 7oh3:O, 7ohp:O, 7ohq:O, 7ohr:O, 7ohs:O, 7oht:O, 7ohu:O, 7ohv:O, 7ohw:O, 7ohx:O, 7ohy:O, 6oig:O, 5on6:w, 5on6:CQ, 7osa:uL13, 7osm:uL13, 8p8m:JW, 8p8n:JW, 8p8u:JW, 8pfr:JW, 6q8y:AU, 7r7a:O, 6r84:Q, 6r86:Q, 6r87:Q, 7rr5:LO, 6s47:AQ, 6snt:u, 6sv4:AU, 6sv4:XU, 6sv4:zU, 6t4q:LO, 5t62:b, 5t6r:b, 6t7i:LO, 6t7t:LO, 6t83:Oy, 6t83:Qa, 5tbw:w, 5tbw:CQ, 6tb3:AU, 5tga:M6, 5tga:m6, 5tgm:M6, 5tgm:m6, 6tnu:AU, 7too:AL16, 7top:AL16, 7u0h:O, 4u3m:M6, 4u3m:m6, 4u3n:M6, 4u3n:m6, 4u3u:M6, 4u3u:m6, 4u4n:M6, 4u4n:m6, 4u4o:M6, 4u4o:m6, 4u4q:M6, 4u4q:m6, 4u4r:M6, 4u4r:m6, 4u4u:M6, 4u4u:m6, 4u4y:M6, 4u4y:m6, 4u4z:M6, 4u4z:m6, 4u50:M6, 4u50:m6, 4u51:M6, 4u51:m6, 4u52:M6, 4u52:m6, 4u53:M6, 4u53:m6, 4u55:M6, 4u55:m6, 4u56:M6, 4u56:m6, 4u6f:M6, 4u6f:m6, 7ug6:O, 7uoo:O, 7uqb:O, 7uqz:O, 7v08:O, 4v4b:BM, 4v7f:J, 4v7r:BP, 4v7r:DP, 4v88:BO, 4v88:DO, 4v8t:O, 4v8y:BO, 4v8z:BO, 8v83:O, 8v84:O, 8v87:O, 4v91:O, 6woo:O, 6xiq:O, 6xir:O, 8y0u:LO, 6ylg:O, 6ylh:O, 6ylx:O, 6yly:O, 5z3g:S, 7z34:O, 6z6j:LO, 6z6k:LO, 7zpq:BN, 7zrs:BN, 7zs5:BP, 7zuw:BN, 7zux:EN, 7zw0:LR
2 6qik:J 197 196 0.8913 0.8325 0.8367 2.14e-111 6qt0:J, 6qtz:J, 6ri5:J, 6rzz:J, 6s05:J
3 5it7:OO 198 196 0.8478 0.7879 0.7959 1.56e-107 6uz7:AO
4 8c3a:w 199 196 0.8152 0.7538 0.7653 1.31e-100 8c3a:BJ, 8cq7:w, 8cq7:BJ, 8cqw:w, 8cqw:BJ, 8cre:w, 8cre:BJ, 8oeq:w, 8oeq:BJ, 7pzy:w, 7q08:w, 7q0f:w, 7q0p:w, 7q0r:w, 8q5i:w
5 8i9p:LO 204 200 0.7120 0.6422 0.6550 4.98e-87 8i9r:LO, 8i9t:LO, 8i9v:LO, 8i9w:LO, 8i9x:LO, 8i9y:LO, 8i9z:LO, 8ia0:LO, 7olc:LO, 7old:LO, 8oo0:LO, 8pv1:LO, 8pv2:LO, 8pv3:LO, 8pv4:LO, 8pv5:LO, 8pv6:LO, 8pv7:LO, 8pv8:LO, 8pvk:LO, 8pvl:LO, 7r81:Q1, 7z3n:LO, 7z3o:LO
6 4v7h:BM 178 142 0.7011 0.7247 0.9085 8.43e-87
7 8esq:O 196 196 0.7011 0.6582 0.6582 1.57e-84 8esr:O, 8etc:O, 8etg:O, 8eth:O, 8eti:O, 8etj:O, 8eug:O, 8eui:O, 8eup:O, 8euy:O, 8ev3:O
8 7oya:O1 204 197 0.5870 0.5294 0.5482 1.89e-68 7oyb:O1
9 8glp:LO 202 171 0.5543 0.5050 0.5965 2.34e-68 7a01:w2, 8a3d:I, 5aj0:AO, 8b5l:O, 8b6c:O, 9bdl:AL16, 9bdn:AL16, 9bdp:AL16, 7bhp:LO, 8bhf:B1, 8bpo:N2, 8btk:BO, 7cpu:LO, 7cpv:LO, 4d5y:O, 4d67:O, 6d90:O, 6d9j:O, 9f1b:BO, 9f1c:BO, 9f1d:BO, 7f5s:LO, 8fkp:L7, 8fkq:L7, 8fkr:L7, 8fks:L7, 8fkt:L7, 8fku:L7, 8fkv:L7, 8fkw:L7, 8fkx:L7, 8fky:L7, 8fkz:L7, 8fl0:L7, 8fl2:L7, 8fl3:L7, 8fl4:L7, 8fl6:L7, 8fl7:L7, 8fl9:L7, 8fla:L7, 8flb:L7, 8flc:L7, 8fld:L7, 8fle:L7, 8flf:L7, 6frk:O, 6ftg:O, 6fti:O, 6ftj:O, 8g5y:LO, 8g5z:LO, 8g60:LO, 8g61:LO, 8g6j:LO, 6gz3:AO, 6gz4:AO, 6gz5:AO, 6hcf:O3, 6hcj:O3, 6hcm:O3, 6hcq:O3, 8idt:V, 8idy:V, 8ie3:V, 8ifd:2I, 8ife:2I, 8ine:V, 8inf:V, 8ink:V, 6ip5:2I, 6ip6:2I, 6ip8:2I, 8ipd:V, 8ipx:V, 8ipy:V, 8ir1:V, 8ir3:V, 3j7o:O, 3j7p:O, 3j7q:O, 3j7r:O, 3j92:O, 3jag:O, 3jah:O, 3jai:O, 3jaj:O, 3jan:O, 8jdj:T, 8jdk:T, 8jdl:T, 8jdm:T, 8k2c:LO, 5lks:LO, 6lqm:V, 6lsr:V, 6lss:V, 7ls1:I2, 7ls2:I2, 6lu8:V, 5lzs:O, 5lzt:O, 5lzu:O, 5lzv:O, 5lzw:O, 5lzx:O, 5lzy:O, 5lzz:O, 7mdz:O, 6mtb:O, 6mtc:O, 6mtd:O, 6mte:O, 7nfx:O, 7nwg:O3, 7nwh:O, 7nwi:O, 7o7y:BO, 7o7z:BO, 7o80:BO, 7o81:BO, 7obr:O, 8ohd:LO, 8oj0:LO, 8oj5:LO, 8oj8:LO, 6ole:P, 6olf:P, 6olg:AO, 6oli:P, 6olz:AO, 6om0:P, 6om7:P, 7ow7:I, 7oyc:O1, 7oyd:O, 8p2k:BO, 6p5i:AO, 6p5j:AO, 6p5k:AO, 6p5n:AO, 8q7z:BO, 8q87:BO, 8qfd:O, 7qgg:P, 8qoi:LO, 7qvp:LO, 7qvp:MO, 7qwq:O, 7qwr:O, 7qws:O, 6qzp:LO, 6r5q:O, 6r6g:O, 6r6p:O, 6r7q:O, 8rjb:O, 8rjc:O, 8rjd:O, 8scb:O, 6sgc:O2, 6swa:N, 5t2c:I, 6t59:O3, 7tm3:O, 7toq:AL16, 7tor:AL16, 7tut:O, 7ucj:O, 7uck:O, 4ug0:LO, 4ujc:BO, 4ujd:AO, 4uje:CO, 4v5z:Bj, 4v6x:CO, 6w6l:P, 6xa1:LO, 7xnx:LO, 7xny:LO, 8xsx:LO, 8xsy:LO, 8xsz:LO, 6y0g:LO, 8y0w:LO, 8y0x:LO, 6y2l:LO, 6y57:LO, 6y6x:LO, 8yoo:LO, 8yop:LO, 6z6l:LO, 6z6m:LO, 6z6n:LO, 7zjw:LR, 7zjx:LR, 6zm7:LO, 6zme:LO, 6zmi:LO, 6zmo:LO, 6zvk:w2
10 4v6w:CO 205 196 0.5707 0.5122 0.5357 9.06e-65 6xu6:CO, 6xu7:CO, 6xu8:CO
11 4v3p:LK 206 191 0.5163 0.4612 0.4974 2.37e-63 8ip8:FB, 8ipa:FB, 8ipb:FB, 8jiv:CO, 4v7e:CO
12 8azw:d 205 191 0.5163 0.4634 0.4974 5.86e-62 8b2l:d3, 7qiw:Q, 7qiz:Q
13 5xxb:N 200 192 0.5326 0.4900 0.5104 1.90e-61
14 4v8p:BI 198 196 0.5326 0.4949 0.5000 3.14e-59 4v8p:CI, 4v8p:EI, 4v8p:GI
15 9bh5:CO 201 195 0.5217 0.4776 0.4923 1.22e-58 9cai:CO
16 3j79:K 201 164 0.4837 0.4428 0.5427 9.27e-58 3jbn:AK, 3jbo:AK, 3jbp:AK, 8tpu:AK, 5umd:K
17 6zj3:LW 208 170 0.4293 0.3798 0.4647 1.05e-51
18 5xy3:O 196 193 0.4783 0.4490 0.4560 8.23e-49
19 8fru:O 196 194 0.4022 0.3776 0.3814 1.52e-40 8br8:LP, 8brm:LP, 8bsi:LP, 8bsj:LP, 8btd:LP, 8btr:LP, 7pwg:O, 7pwo:O2
20 8a98:H 221 167 0.4076 0.3394 0.4491 2.24e-39 8a3w:H, 6az3:H, 3jcs:H, 8ovj:H, 8rxh:LH, 8rxx:LH, 5t2a:M
21 5t5h:O 202 188 0.4185 0.3812 0.4096 1.25e-37
22 8ova:BO 221 166 0.3913 0.3258 0.4337 9.66e-37 8ove:BO, 4v8m:BO
23 6zu5:LO0 196 165 0.3424 0.3214 0.3818 8.88e-34
24 6rm3:LO0 173 150 0.2935 0.3121 0.3600 5.52e-27
25 8p5d:LO0 198 172 0.2935 0.2727 0.3140 1.36e-23 8p60:LO0, 8p60:KO0, 7qca:LO0
26 7qep:M6 196 192 0.3533 0.3316 0.3385 1.86e-22
27 6skf:BK 142 142 0.2717 0.3521 0.3521 4.57e-16 6skg:BK, 6th6:BK, 4v4n:AI, 4v6u:BI
28 4v9f:J 144 136 0.2446 0.3125 0.3309 5.32e-16 3cc2:J, 3cc4:J, 3cc7:J, 3cce:J, 3ccj:J, 3ccl:J, 3ccm:J, 3ccq:J, 3ccr:J, 3ccs:J, 3ccu:J, 3ccv:J, 3cd6:J, 3cma:J, 3cme:J, 3cpw:I, 3cxc:I, 1ffk:G, 3g4s:J, 3g6e:J, 3g71:J, 3i55:J, 3i56:J, 1jj2:I, 1k73:K, 1k8a:K, 1k9m:K, 1kc8:K, 1kd1:K, 1kqs:I, 1m1k:K, 1m90:K, 1n8r:K, 1nji:K, 2otj:J, 2otl:J, 3ow2:I, 1q7y:K, 1q81:K, 1q82:K, 1q86:K, 2qa4:J, 2qex:J, 1qvf:I, 1qvg:I, 1s72:J, 4v4p:AM, 4v4r:BN, 4v4s:BN, 4v4t:BN, 1vq4:J, 1vq5:J, 1vq6:J, 1vq7:J, 1vq8:J, 1vq9:J, 1vqk:J, 1vql:J, 1vqm:J, 1vqn:J, 1vqo:J, 1vqp:J, 1w2b:I, 1yhq:J, 1yi2:J, 1yij:J, 1yit:J, 1yj9:J, 1yjn:J, 1yjw:J
29 7unr:L 142 131 0.1957 0.2535 0.2748 3.55e-08 8cd1:J, 6spb:J, 6spd:J, 6spf:J, 6spg:J, 7unu:L, 7unv:L, 7unw:L
30 8hku:L13P 140 142 0.2500 0.3286 0.3239 3.19e-07 8hkv:L13P, 8hky:L13P, 8hkz:L13P, 8hl1:L13P, 8hl2:L13P, 8hl3:L13P, 8hl4:L13P, 8hl5:L13P
31 7m4v:I 142 131 0.1957 0.2535 0.2748 2.38e-06 7m4w:I, 7m4x:I, 7m4y:I, 7m4z:I, 7ryf:I, 7ryg:I, 7ryh:I, 7uvv:I, 7uvw:I, 7uvx:I, 7uvy:I, 7uvz:I, 7uw1:I, 6v39:I, 6v3a:I, 6v3b:I, 6v3d:I, 6yhs:F, 6ysi:F
32 8rd8:IX 142 121 0.1739 0.2254 0.2645 1.58e-05 8rdv:IX, 8rdw:IX
33 7a0r:G 143 136 0.1957 0.2517 0.2647 1.11e-04 7a0s:G, 7a18:G, 3cf5:G, 3dll:G, 5dm6:G, 5dm7:G, 4io9:G, 4ioa:G, 4ioc:G, 5jvg:G, 5jvh:G, 3pio:G, 3pip:G, 1sm1:H, 4u67:G, 4v4g:BK, 4v4g:DK, 4v4g:FK, 4v4g:HK, 4v4g:JK, 4wfn:G, 1xbp:H, 2zjp:G, 2zjq:G, 2zjr:G
34 8buu:J 144 122 0.1467 0.1875 0.2213 1.22e-04 7aqc:J, 7aqd:J, 7as8:N, 7as9:N, 6ha1:J, 6ha8:J, 6htq:J, 3j3v:J, 3j3w:J, 3j9w:BM, 5njt:c, 7o5b:e, 7ope:N, 6ppf:J, 6ppk:J, 6pvk:J, 8qcq:J, 7qgu:J, 7qh4:J, 8qpp:e, 7qv1:J, 7qv2:J, 7qv3:J, 8r55:e, 8s1p:J, 8s1u:J, 7s9u:J, 7sae:J, 6tnn:c, 6tpq:c
35 5mmi:K 203 126 0.1902 0.1724 0.2778 2.30e-04 6eri:AJ, 5h1s:L, 5mlc:L, 5mmm:K, 4v61:BL, 5x8p:K, 5x8t:K
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38 5myj:BM 147 134 0.2011 0.2517 0.2761 0.001
39 7jil:J 150 113 0.1576 0.1933 0.2566 0.001
40 6xyw:Aj 155 137 0.1902 0.2258 0.2555 0.008
41 5zeb:K 147 117 0.1739 0.2177 0.2735 0.008 6dzi:K, 6dzp:K, 8fr8:T, 8kab:K, 5o60:K, 5o61:K, 7s0s:L, 8v9j:L, 8v9k:L, 8v9l:L, 8whx:M, 8why:M, 8wi7:M, 8wi8:M, 8wib:M, 8wic:M, 7xam:K, 5xym:J, 8xz3:K, 7y41:K, 5zep:K, 5zet:K
42 7pkt:i 152 110 0.1685 0.2039 0.2818 0.020
43 5mrc:H 160 110 0.1739 0.2000 0.2909 0.025 3j6b:H, 5mre:H, 5mrf:H
44 7asm:H 145 117 0.1522 0.1931 0.2393 0.10 7asn:H, 7aso:M, 7asp:H, 6ddd:V, 6ddg:V, 6fxc:AH, 6fxc:BH, 5hkv:G, 5hl7:G, 6hma:H, 5li0:M, 5nd8:M, 5nd9:M, 5ngm:AH, 7nhl:M, 7nhm:M, 5nrg:G, 8p2f:M, 8p2g:M, 8p2h:M, 7p48:H, 6s0x:H, 6s0z:H, 6s12:H, 6s13:H, 6sj6:M, 5t7v:LM, 5tcu:LM, 7ttu:V, 7ttw:V, 4wce:G, 4wf9:G, 4wfa:G, 4wfb:G, 6wqn:V, 6wqq:V, 6wrs:V, 6wru:V, 8y36:H, 8y37:H, 8y38:H, 8y39:H, 6yef:M
45 7xzi:A 1598 106 0.1739 0.0200 0.3019 0.23
46 9c4g:i 146 117 0.1576 0.1986 0.2479 0.32 8crx:i, 8cvm:i
47 8uu4:L 143 112 0.1304 0.1678 0.2143 0.64 8a57:M, 8a5i:M, 8a63:M, 7nhn:M, 8uu5:L, 8uu6:L, 8uu7:L, 8uu8:L, 8uu9:L, 8uua:L
48 6i5x:B 261 108 0.1522 0.1073 0.2593 2.2 6i5x:A, 6i5x:C, 6i5x:D
49 6kev:A 317 63 0.1033 0.0599 0.3016 3.1
50 7pw4:C 310 81 0.1141 0.0677 0.2593 3.9 6l54:C, 7pw5:C, 7pw7:C, 7pw8:C, 7pw9:C, 6syt:C, 6z3r:C
51 4ydp:A 83 48 0.0815 0.1807 0.3125 5.2 4ydp:B
52 5jiz:A 151 32 0.0652 0.0795 0.3750 6.1 6bq8:A, 5bv6:A, 5jix:A
53 1ohd:A 338 38 0.0707 0.0385 0.3421 6.2 1ohe:A
54 6ywe:H 183 110 0.1522 0.1530 0.2545 6.8 6yws:H, 6ywv:H, 6ywx:H, 6ywy:H
55 2cs8:A 108 59 0.0815 0.1389 0.2542 7.2
56 7mvv:A 1542 26 0.0435 0.0052 0.3077 8.7 4knh:B, 7tbi:I1, 7tbi:I2, 7tbj:I1, 7tbj:I2, 7tbj:I3, 7tbj:I4, 7tbj:I5, 7tbk:I1, 7tbk:I2, 7tbk:I3, 7tbk:I4, 7tbk:I5, 7tbl:I1, 7tbl:I2, 7tbl:I3, 7tbl:I4, 7tbl:I5, 7tbm:I1, 7tbm:I2, 7tbm:I3, 7tbm:I4, 7tbm:I5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218