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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKDMTRIRIDELEPRRPR
YRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPGAWEETFK
THSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDL
GIFWLNAAETWVDISSNTPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVL
EVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYV
KTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRD
IHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGG
FFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLW
VQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIV
PRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIE
RVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPGVSVASDWSIHLR

The query sequence (length=854) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ief:A 858 857 0.9988 0.9942 0.9953 0.0 5h9o:A, 5h9o:C, 5hjo:A, 5hjo:C, 5hjr:A, 5hjr:C, 5ied:A, 5iee:A, 5ieg:A, 7jty:A, 7jty:C, 7k9n:A, 7k9n:C, 7k9o:A, 7k9o:C, 7k9q:A, 7k9q:C, 7k9t:A, 7k9t:C, 7kad:A, 7kad:C, 7kb6:A, 7kb6:C, 7kb8:A, 7kb8:C, 7kbj:A, 7kbj:C, 7kbr:A, 7kbr:C, 7kry:A, 7kry:C
2 5dky:A 928 882 0.4543 0.4181 0.4399 0.0 5dkz:A, 5dl0:A
3 5kzw:A 850 704 0.2799 0.2812 0.3395 2.61e-105 8cb1:A, 8cb6:A, 5kzx:A, 5nn4:A, 5nn5:A, 5nn6:A, 5nn8:A, 7p2z:AaA, 7p32:AAA
4 3wem:A 830 682 0.2553 0.2627 0.3196 2.06e-92 3w37:A, 3wel:A, 3wen:A, 3weo:A
5 3l4u:A 864 691 0.2518 0.2488 0.3111 7.62e-86 3ctt:A, 3l4t:A, 3l4v:A, 3l4w:A, 3l4x:A, 3l4y:A, 3l4z:A, 2qmj:A
6 3lpp:B 869 824 0.2681 0.2635 0.2779 1.10e-81 3lpp:D
7 6c9x:A 666 666 0.2073 0.2658 0.2658 4.64e-78 6c9x:B, 6c9z:A, 6c9z:B, 6ca1:A, 6ca1:B, 6ca3:A, 6ca3:B, 3mkk:B, 3mkk:A, 3pha:A, 3pha:B, 3pha:C, 3pha:D, 3poc:B, 3poc:A
8 6jr7:A 812 616 0.2084 0.2192 0.2890 2.85e-70 6jr7:B, 6jr7:C, 6jr7:D, 6jr8:A, 6jr8:B, 6jr8:C, 6jr8:D
9 3top:A 890 642 0.2155 0.2067 0.2866 5.41e-66 3top:B
10 4ba0:A 781 583 0.1979 0.2164 0.2899 1.05e-56 4b9y:A, 4b9z:A, 5i23:A, 5i24:A, 5npb:A, 5npc:A, 5npd:A, 5npe:A, 7p4c:AAA, 7p4d:AAA, 8rw3:C, 8rw3:A, 8rw3:B
11 5jov:A 949 560 0.1792 0.1612 0.2732 6.99e-47
12 7knc:A 919 541 0.1686 0.1567 0.2662 7.14e-42
13 5zn7:A 680 669 0.1979 0.2485 0.2526 3.84e-41 5zn7:C, 5zn7:D, 5zn7:F, 5zn7:H
14 5x7o:A 1247 541 0.1674 0.1147 0.2643 7.97e-41 5x7o:B, 5x7p:B, 5x7p:A, 5x7q:A, 5x7q:B, 5x7r:A, 5x7r:B, 5x7s:A, 5x7s:B
15 2xvk:A 944 552 0.1651 0.1494 0.2554 2.18e-40 2xvl:A
16 7xoi:B 436 379 0.1230 0.2408 0.2770 7.72e-40 7xoi:D, 7xoi:F, 7xoi:H, 7xoi:J, 7xoi:L, 7xoi:N, 7xoi:P
17 7xoi:A 465 309 0.1124 0.2065 0.3107 3.95e-39 7xoi:C, 7xoi:E, 7xoi:G, 7xoi:I, 7xoi:K, 7xoi:M, 7xoi:O
18 2f2h:A 773 555 0.1698 0.1876 0.2613 1.93e-38 2f2h:B, 2f2h:C, 2f2h:D, 2f2h:E, 2f2h:F, 1xsk:A, 1xsk:B, 1xsk:C, 1xsk:E
19 6dru:A 718 597 0.1803 0.2145 0.2580 4.44e-35 6dru:B
20 5hxm:A 1060 497 0.1417 0.1142 0.2435 2.51e-32 5f7u:A, 5hpo:A, 5i0d:A, 5i0d:B, 4kmq:A, 4kwu:A
21 4xpq:A 670 559 0.1663 0.2119 0.2540 3.60e-29 4xpp:A, 4xps:A
22 5x3j:A 718 590 0.1756 0.2089 0.2542 4.39e-26 5x3j:B, 5x3k:A, 5x3k:B
23 5i0g:B 730 596 0.1721 0.2014 0.2466 6.00e-26 5f7s:A, 5f7s:B, 5i0e:B, 5i0f:B
24 7wj9:A 733 500 0.1323 0.1542 0.2260 1.12e-25 7wj9:B, 7wj9:C, 7wj9:D, 7wj9:F, 7wj9:E, 7wjb:A, 7wjc:A, 7wjd:A, 7wje:A, 7wjf:A
25 6m77:A 907 312 0.0867 0.0816 0.2372 4.55e-25 7f7q:A, 7f7r:A
26 4amw:A 1025 738 0.1920 0.1600 0.2222 1.88e-23 4amw:B, 4amw:C, 4amw:D, 4amx:A, 4amx:B, 4amx:C, 4amx:D, 2x2i:A, 2x2i:B, 2x2i:C, 2x2i:D, 2x2j:A, 2x2j:B, 2x2j:C, 2x2j:D
27 5aed:A 674 389 0.1206 0.1528 0.2648 3.99e-23 5aed:B, 5aee:A, 5aee:B, 5aeg:A, 5aeg:B, 5oht:A, 5oht:B
28 8r56:D 673 401 0.1101 0.1397 0.2344 6.08e-21 8r56:A, 8r56:B, 8r56:C
29 6pnr:A 667 391 0.1136 0.1454 0.2481 1.38e-20 6pnr:C
30 7ofx:B 665 395 0.1265 0.1624 0.2734 1.65e-19 7ofx:A, 7ofx:C, 7ofx:D, 5ohs:A, 5ohs:B, 5ohs:C, 5ohs:D, 5ohs:E, 5ohs:F, 5ohs:G, 5ohs:H, 5ohy:A, 5ohy:B, 5ohy:C, 5ohy:D
31 8j51:A 510 410 0.1218 0.2039 0.2537 5.64e-16 8j51:B, 8j52:A, 8j52:B
32 7qqg:B 623 424 0.1253 0.1717 0.2524 1.63e-12 7qqg:A, 7qqg:C, 7qqh:A, 7qqh:B, 7qqh:C, 7qqh:D
33 7qqg:D 496 423 0.1241 0.2137 0.2506 8.79e-11
34 8fmw:AL 145 38 0.0152 0.0897 0.3421 0.99 8fn2:L
35 5b8i:A 359 81 0.0246 0.0585 0.2593 1.0 6tz7:A
36 7d5s:5K 175 97 0.0281 0.1371 0.2474 1.0 7ajt:UX, 7aju:UX, 7d4i:5K, 7d5t:5K, 7d63:5K, 6ke6:5K, 6lqp:5K, 6lqq:5K, 6lqr:5K, 6lqs:5K, 6lqt:5K, 6lqu:5K, 6lqv:5K, 7suk:SL, 5wlc:SL, 5wyj:U4, 5wyk:U4, 6zqb:UX, 6zqc:UX, 6zqd:UX, 6zqe:UX, 6zqg:UX
37 5vxc:A 301 114 0.0328 0.0930 0.2456 1.3 5vxo:A, 5vxo:B, 5vxo:C
38 7rka:A 211 98 0.0269 0.1090 0.2347 8.4
39 3thu:A 405 57 0.0187 0.0395 0.2807 9.1 3thu:B, 3thu:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218