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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGD
GEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYTEIRYRQRYLDL
LINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDK
VYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKV
SIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKY
HRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFQLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILF
PTMRPA

The query sequence (length=486) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6agt:B 506 505 1.0000 0.9605 0.9624 0.0 6agt:A, 6agt:C, 6agt:D, 7bt5:A, 7bt5:B, 6hcu:A, 6hcu:B, 6hcv:A, 6hcv:B, 8k9s:A, 8k9s:B, 8k9u:A, 8k9u:B, 8k9v:A, 8k9v:B, 8k9w:A, 8k9w:B, 8k9x:A, 8k9x:B, 6ka6:A, 6ka6:B, 6ka6:C, 6ka6:D, 6kab:A, 6kab:B, 6kab:C, 6kab:D, 6kbf:A, 6kbf:B, 6kcn:A, 6kcn:B, 6kcn:C, 6kcn:D, 6kct:A, 6kct:B, 6kct:C, 6kct:D, 6l3y:B, 6l3y:A, 6l4q:B, 6l4q:A, 6m0t:A, 6m0t:B, 6m0t:C, 6m0t:D, 4pg3:A, 4pg3:B, 4pg3:C, 4pg3:D, 4ycv:A, 4ycv:B, 4ycv:C, 4ycv:D, 5zh2:B, 5zh3:A, 5zh3:B, 5zh4:A, 5zh4:B, 5zh5:A, 5zh5:B
2 5zh2:A 464 485 0.9527 0.9978 0.9546 0.0
3 6bni:A 502 499 0.5514 0.5339 0.5371 0.0 6bni:B, 6c86:A, 6c86:B, 5eln:A, 5eln:B, 5eln:C, 5eln:D, 5elo:A, 5elo:B, 5elo:C, 5elo:D, 6hcw:A, 6hcw:B, 7zog:A, 7zog:B, 7zog:C, 7zog:D
4 6chd:A 506 507 0.5576 0.5356 0.5345 0.0 3bju:A, 3bju:B, 3bju:C, 3bju:D, 6chd:B, 4dpg:A, 4dpg:B, 4dpg:C, 4dpg:D, 4dpg:E, 4dpg:F, 4dpg:G, 4dpg:H, 7ea9:A, 7ea9:B, 7ea9:C, 7ea9:D, 6ild:A, 6ild:B, 6ilh:A, 6ilh:B, 4ycu:A, 4ycu:B, 4ycw:A, 4ycw:B, 4ycw:E, 4ycw:F
5 5hgq:B 482 489 0.5432 0.5477 0.5399 0.0 5hgq:A, 5hgq:D, 5hgq:C
6 7f6w:A 506 509 0.5123 0.4921 0.4892 9.88e-170
7 4up7:A 529 503 0.4630 0.4253 0.4473 9.60e-149 4up9:A, 4upa:A
8 3a74:A 484 483 0.4239 0.4256 0.4265 1.98e-120 3a74:B, 3a74:C, 3a74:D, 3e9h:A, 3e9h:B, 3e9h:C, 3e9h:D, 3e9i:A, 3e9i:B, 3e9i:C, 3e9i:D
9 1e1t:A 485 500 0.4259 0.4268 0.4140 5.35e-115 1e1o:A, 1e22:A, 1e24:A, 1lyl:A, 1lyl:B, 1lyl:C, 5yzx:A, 5yzx:B, 5yzx:C
10 1bbu:A 486 506 0.4218 0.4218 0.4051 1.62e-108
11 4ex5:A 486 500 0.3827 0.3827 0.3720 1.65e-97 4ex5:B
12 6aqg:C 490 502 0.3663 0.3633 0.3546 5.07e-97 6aqg:A, 6aqg:B, 6aqg:D, 5vl1:A, 5vl1:B, 5vl1:C, 5vl1:D
13 6wbd:B 485 506 0.3807 0.3814 0.3656 2.15e-96 6wbd:A
14 6nrz:A 517 516 0.3724 0.3501 0.3508 4.21e-93 6nrz:B, 6ns0:A, 6ns0:B, 6o3f:A, 6o3f:B
15 6aqh:B 490 506 0.3560 0.3531 0.3419 1.73e-85 6aqh:A, 6aqh:C, 6aqh:D
16 7qh8:A 471 499 0.3519 0.3631 0.3427 6.60e-80 7qhn:A, 7qi8:A
17 3a5z:C 324 336 0.1728 0.2593 0.2500 1.24e-23 3a5y:B, 3a5y:C, 3a5y:D, 3a5z:A, 3a5z:E, 3a5z:G, 3g1z:A, 3g1z:B
18 3a5y:A 297 336 0.1667 0.2727 0.2411 4.95e-22
19 1b8a:A 438 410 0.2119 0.2352 0.2512 6.94e-19 1b8a:B, 3nel:A, 3nem:A, 3nem:B
20 1asy:A 490 353 0.1626 0.1612 0.2238 4.25e-12 1asy:B, 1asz:A, 1asz:B
21 4wj3:M 589 139 0.0844 0.0696 0.2950 3.70e-11 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
22 4wj3:M 589 92 0.0597 0.0492 0.3152 8.20e-08 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
23 1c0a:A 585 144 0.0885 0.0735 0.2986 4.65e-10 1il2:A, 1il2:B
24 1c0a:A 585 55 0.0514 0.0427 0.4545 1.19e-06 1il2:A, 1il2:B
25 6sjc:B 581 157 0.0782 0.0654 0.2420 6.18e-10 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
26 6sjc:B 581 109 0.0720 0.0602 0.3211 9.69e-08 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
27 5w25:A 583 179 0.0988 0.0823 0.2682 1.83e-09 5w25:B
28 5w25:A 583 33 0.0329 0.0274 0.4848 0.001 5w25:B
29 4o2d:B 515 180 0.0988 0.0932 0.2667 1.23e-08
30 4o2d:B 515 54 0.0473 0.0447 0.4259 3.80e-05
31 4o2d:A 580 180 0.0988 0.0828 0.2667 1.30e-08 4rmf:A
32 4o2d:A 580 54 0.0473 0.0397 0.4259 4.68e-05 4rmf:A
33 3kfu:C 377 376 0.1564 0.2016 0.2021 2.52e-08 3kfu:A, 3kfu:D, 3kfu:B
34 2xgt:B 433 163 0.0967 0.1085 0.2883 2.81e-06 2xgt:A, 2xti:A, 2xti:B
35 8tc8:A 435 468 0.2058 0.2299 0.2137 1.77e-05 8h53:A, 8h53:B, 8h53:C, 8h53:D, 8tc8:B, 8tc8:C, 8tc8:D, 8tc9:A, 8tc9:B, 8tc9:C, 8tc9:D
36 1x54:A 434 347 0.1646 0.1843 0.2305 2.11e-05 1x55:A
37 3m4p:A 435 336 0.1379 0.1540 0.1994 7.03e-05 3m4p:B, 3m4p:C, 3m4p:D
38 3p8v:A 294 331 0.1399 0.2313 0.2054 0.029 3p8v:B, 3p8y:A, 3p8y:B, 3reu:A, 3reu:B, 3rex:A, 3rex:B, 3rl6:A, 3rl6:B
39 7u0r:B 278 116 0.0679 0.1187 0.2845 0.21 8c49:A, 8c49:B, 8dqg:D, 8dqg:A, 8dqh:D, 8dqh:A, 8dqi:D, 8dqi:A, 8dqj:D, 7u0r:A
40 6hxi:C 410 81 0.0535 0.0634 0.3210 0.28 6hxi:A, 6znw:A
41 8ci0:AAA 666 193 0.0885 0.0646 0.2228 1.2 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
42 7by6:A 299 26 0.0267 0.0435 0.5000 1.8
43 3mbo:E 375 84 0.0453 0.0587 0.2619 2.3 3mbo:A, 3mbo:C, 3mbo:H
44 7dpi:C 292 26 0.0267 0.0445 0.5000 2.3 7dpi:A
45 3l4g:C 508 55 0.0370 0.0354 0.3273 3.4 3l4g:A, 3l4g:E, 3l4g:G, 3l4g:I, 3l4g:K, 3l4g:M, 3l4g:O
46 2du3:A 534 68 0.0350 0.0318 0.2500 3.7 2du5:A, 2du6:A
47 2du4:A 466 68 0.0350 0.0365 0.2500 3.7 2du3:B, 2du5:B, 2du6:B
48 5mgu:A 407 44 0.0309 0.0369 0.3409 4.0 3cmq:A, 3hfv:A, 5mgh:A, 5mgw:A, 8p8x:A, 3teg:A, 3tup:A
49 6z1p:BS 433 130 0.0658 0.0739 0.2462 4.7
50 6ha8:V 541 42 0.0267 0.0240 0.3095 6.7
51 4ylr:A 331 163 0.0782 0.1148 0.2331 7.3 4yls:A
52 5hb3:C 709 27 0.0288 0.0197 0.5185 8.0 5hb3:A, 7tbi:D1, 7tbi:D2, 7tbi:D3, 7tbi:D4
53 3m49:A 665 84 0.0473 0.0346 0.2738 9.7 3hyl:A, 3hyl:B, 3m49:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218