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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VDICTAKPRDIPMNPMCIYRSPQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGAC
NDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDF
KENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQE
GKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQL
QDMGLVDLFSPEKSKLPGIDDLYVSDAFHKAFLEVNEEGAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIF
MGRVANPCV

The query sequence (length=409) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1e03:L 423 423 1.0000 0.9669 0.9669 0.0 1azx:I, 1azx:L, 2b5t:I, 1br8:I, 1e03:I, 3evj:I, 3evj:L, 2gd4:I, 2gd4:C, 1jvq:I, 3kcg:I, 1lk6:I, 1nq9:I, 1nq9:L, 1r1l:I, 1sr5:A, 1tb6:I
2 4zk0:A 367 377 0.3447 0.3842 0.3740 3.49e-75
3 7qrn:A 364 386 0.3276 0.3681 0.3472 4.20e-65
4 2arq:A 360 383 0.3178 0.3611 0.3394 2.29e-62 2arr:A, 1jrr:A
5 8h4x:A 330 330 0.3007 0.3727 0.3727 3.65e-60
6 8gxv:A 353 376 0.2983 0.3456 0.3245 1.03e-59
7 1ova:A 385 367 0.2910 0.3091 0.3243 1.55e-56
8 4aqh:B 383 377 0.2641 0.2820 0.2865 2.55e-53 1a7c:A, 4aqh:A, 4aqh:C, 7aqf:A, 7aqg:A, 1dvm:A, 1dvm:C, 1dvm:D, 4g8o:D, 4g8r:A, 4g8r:B, 4ic0:A, 4ic0:C, 3q02:A, 3q02:B, 3q03:A, 3q03:B, 3r4l:A, 3ut3:B
9 1jmj:A 397 383 0.3081 0.3174 0.3290 1.09e-52
10 4c49:A 367 378 0.2958 0.3297 0.3201 5.78e-52 4bb2:A, 4bb2:B, 4c49:B, 4c49:C, 4c49:D, 2vdy:A, 2vdy:B
11 4dy7:F 378 363 0.2861 0.3095 0.3223 2.05e-51
12 5hgc:A 373 373 0.2885 0.3164 0.3164 2.04e-49
13 1hp7:A 376 373 0.2689 0.2926 0.2949 1.25e-43 7ael:AAA, 7api:A, 8api:A, 9api:A, 6i4v:A, 1iz2:A, 7npl:A, 8pi2:A, 4pyw:A
14 7b2t:A 342 329 0.2494 0.2982 0.3100 4.25e-42 7b2t:B
15 6hgg:A 339 341 0.2714 0.3274 0.3255 1.65e-41 6ftp:A, 6hgf:A, 6hgi:A, 6hgk:A, 6hgl:A, 6hgm:A, 5om2:A, 5om3:A, 5om7:A
16 1lq8:G 330 338 0.2445 0.3030 0.2959 3.89e-39 3dy0:A, 1lq8:A, 1lq8:C, 1lq8:E
17 7rbw:A 381 389 0.2665 0.2861 0.2802 4.98e-39 7rbw:B
18 7npk:A 352 372 0.2616 0.3040 0.2876 1.28e-36
19 6f4v:A 341 331 0.2641 0.3167 0.3263 1.96e-36
20 3zha:A 380 376 0.2200 0.2368 0.2394 7.51e-35 4au2:A, 4au2:B, 4au2:D, 4au3:A, 4au3:B, 4au3:C, 4au3:D, 7bdu:A, 7bdu:B, 7bee:A, 7bee:B, 7bfi:A, 7bfi:C, 7bfi:D, 7bfi:B, 3zha:B, 3zha:C, 3zha:D, 3zha:K, 3zha:L, 3zha:P, 3zha:Q
21 4x30:A 372 380 0.2567 0.2823 0.2763 1.24e-34 2ceo:A, 2ceo:B, 2riw:A, 2riw:B, 2xn3:A, 2xn3:B, 2xn5:A, 2xn6:A, 2xn6:B, 2xn7:A, 2xn7:B, 4yia:A, 4yia:B
22 5ncw:A 334 315 0.2372 0.2904 0.3079 1.59e-34 5nct:A
23 2v95:A 342 374 0.2421 0.2895 0.2647 1.40e-31
24 6los:A 369 380 0.2567 0.2846 0.2763 1.54e-30
25 4au2:C 338 376 0.2029 0.2456 0.2207 3.79e-26
26 8h4x:B 32 28 0.0342 0.4375 0.5000 0.009
27 8qqk:B 263 73 0.0538 0.0837 0.3014 0.38 1cyx:A, 1fft:B, 8go3:B, 7n9z:G, 6wti:B, 7xmc:B, 7xmd:B
28 3w6x:A 225 73 0.0587 0.1067 0.3288 0.46 3w6x:B, 3w6x:C, 3w6x:F
29 6pd2:C 616 56 0.0440 0.0292 0.3214 0.59 6pd1:A, 6pd1:B, 6pd1:D, 6pd2:A, 6pd2:B, 6pd2:D
30 1as4:B 33 25 0.0293 0.3636 0.4800 0.79
31 6hgi:B 35 31 0.0318 0.3714 0.4194 0.88 6ftp:B, 6hgf:B, 6hgg:B, 6hgj:B, 6hgk:B, 6hgl:B, 5om2:B, 5om3:B, 5om7:B
32 7ohd:B 134 48 0.0416 0.1269 0.3542 1.1
33 2ovq:B 444 58 0.0489 0.0450 0.3448 1.8 2ovr:B, 7t1y:B, 7t1z:B, 5v4b:B
34 5dat:S3 223 101 0.0685 0.1256 0.2772 2.4 7a1g:A, 7b7d:A, 8bn3:S3, 8bqd:A, 8bqx:A, 8cah:A, 8cas:B, 8cbj:D, 5dat:s3, 5dc3:S3, 5dc3:s3, 5dge:S3, 5dge:s3, 5dgf:S3, 5dgf:s3, 5dgv:S3, 5dgv:s3, 8eub:BD, 8evp:BD, 8evq:BD, 8evr:BD, 8evs:BD, 8evt:BD, 8ewb:BD, 8ewc:BD, 6fai:D, 5fci:S3, 5fci:s3, 5fcj:S3, 5fcj:s3, 6gq1:t, 6gqb:t, 6gqv:t, 6hhq:E, 6hhq:s3, 5i4l:S3, 5i4l:s3, 6i7o:A, 6i7o:Ab, 3j6x:S3, 3j6y:S3, 3j77:S3, 3j78:S3, 5juo:AB, 5jup:AB, 5jus:AB, 5jut:AB, 5juu:AB, 8k2d:SD, 8k82:SD, 5lyb:S3, 5lyb:s3, 5m1j:D2, 5mc6:A, 5mei:s3, 5mei:E, 7mpi:BD, 7mpj:BD, 7n8b:BD, 5ndg:S3, 5ndg:s3, 5ndv:S3, 5ndv:s3, 5ndw:S3, 5ndw:s3, 7nrc:SA, 7nrd:SA, 5obm:S3, 5obm:s3, 5on6:s3, 5on6:E, 6q8y:A, 6rbe:D, 7rr5:SD, 6s47:BE, 6snt:D, 6sv4:A, 6sv4:Ab, 6sv4:Ac, 6t4q:SD, 6t7i:SD, 6t7t:SD, 6t83:Db, 6t83:e, 5tbw:E, 5tbw:s3, 6tb3:A, 5tga:S3, 5tga:s3, 5tgm:S3, 5tgm:s3, 6tnu:A, 4u3m:S3, 4u3m:s3, 4u3n:S3, 4u3n:s3, 4u3u:S3, 4u3u:s3, 4u4n:S3, 4u4n:s3, 4u4o:S3, 4u4o:s3, 4u4q:S3, 4u4q:s3, 4u4r:S3, 4u4r:s3, 4u4u:S3, 4u4u:s3, 4u4y:S3, 4u4y:s3, 4u4z:S3, 4u4z:s3, 4u50:S3, 4u50:s3, 4u51:S3, 4u51:s3, 4u52:S3, 4u52:s3, 4u53:S3, 4u53:s3, 4u55:S3, 4u55:s3, 4u56:S3, 4u56:s3, 4u6f:S3, 4u6f:s3, 4uer:C, 4v88:AD, 4v88:CD, 4v8y:AD, 4v8z:AD, 4v92:BD, 6wdr:D, 6woo:DD, 6xiq:t, 6xir:t, 6z6j:SD, 6z6k:SD, 6zce:E, 7zpq:AD, 7zrs:AD, 6zu9:B, 7zuw:AD, 7zux:DD, 6zvi:l, 7zw0:sA
35 6p8v:G 320 75 0.0465 0.0594 0.2533 3.4 6p80:A, 6u7b:A, 6u7b:C
36 4grs:A 333 39 0.0367 0.0450 0.3846 3.7 4c1k:A, 4c1k:B, 4c1k:C, 4c1k:D, 4c1k:E, 4c1k:F, 4c1l:A, 4c1l:B, 4grs:C, 4grs:B, 4grs:D, 1zco:A, 1zco:B
37 5m1k:B 189 29 0.0367 0.0794 0.5172 3.8 5m1n:A, 5m1n:B, 5m1o:A, 5m1o:B, 5m1p:A, 5m1q:A
38 8f9x:A 230 45 0.0318 0.0565 0.2889 9.2 8f9x:B, 8f9x:C, 8f9x:D, 8f9x:E, 8f9x:F, 8f9x:G, 8f9x:H, 8f9x:I, 8f9x:J
39 6avz:B 347 105 0.0660 0.0778 0.2571 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218