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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VDICTAKPRDIPMNPMCIYRSPEEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFA
MTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGA
KLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCS
ASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDG
FSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPF
LVFIREVPLNTIIFMGRVANPCV

The query sequence (length=423) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1e03:L 423 423 1.0000 1.0000 1.0000 0.0 1azx:I, 1azx:L, 2b5t:I, 1br8:I, 1e03:I, 3evj:I, 3evj:L, 2gd4:I, 2gd4:C, 1jvq:I, 3kcg:I, 1lk6:I, 1nq9:I, 1nq9:L, 1r1l:I, 1sr5:A, 1tb6:I
2 4zk0:A 367 382 0.3546 0.4087 0.3927 1.64e-74
3 7qrn:A 364 390 0.3168 0.3681 0.3436 1.20e-64
4 2arq:A 360 387 0.3097 0.3639 0.3385 1.15e-62 2arr:A, 1jrr:A
5 8h4x:A 330 334 0.2979 0.3818 0.3772 8.89e-62
6 8gxv:A 353 379 0.2908 0.3484 0.3245 3.06e-60
7 1ova:A 385 369 0.2837 0.3117 0.3252 8.05e-59
8 4dy7:F 378 363 0.2719 0.3042 0.3168 2.14e-54
9 4aqh:B 383 379 0.2530 0.2794 0.2823 5.64e-54 1a7c:A, 4aqh:A, 4aqh:C, 7aqf:A, 7aqg:A, 1dvm:A, 1dvm:C, 1dvm:D, 4g8o:D, 4g8r:A, 4g8r:B, 4ic0:A, 4ic0:C, 3q02:A, 3q02:B, 3q03:A, 3q03:B, 3r4l:A, 3ut3:B
10 4c49:A 367 381 0.2861 0.3297 0.3176 5.35e-53 4bb2:A, 4bb2:B, 4c49:B, 4c49:C, 4c49:D, 2vdy:A, 2vdy:B
11 1jmj:A 397 389 0.3002 0.3199 0.3265 1.20e-50
12 5hgc:A 373 378 0.2837 0.3217 0.3175 1.80e-49
13 6hgg:A 339 346 0.2790 0.3481 0.3410 8.85e-45 6ftp:A, 6hgf:A, 6hgi:A, 6hgk:A, 6hgl:A, 6hgm:A, 5om2:A, 5om3:A, 5om7:A
14 1hp7:A 376 376 0.2648 0.2979 0.2979 1.04e-44 7ael:AAA, 7api:A, 8api:A, 9api:A, 6i4v:A, 1iz2:A, 7npl:A, 8pi2:A, 4pyw:A
15 7b2t:A 342 333 0.2459 0.3041 0.3123 3.09e-44 7b2t:B
16 1lq8:G 330 340 0.2364 0.3030 0.2941 4.35e-41 3dy0:A, 1lq8:A, 1lq8:C, 1lq8:E
17 7rbw:A 381 393 0.2553 0.2835 0.2748 4.31e-38 7rbw:B
18 6f4v:A 341 333 0.2577 0.3196 0.3273 8.86e-37
19 7npk:A 352 376 0.2553 0.3068 0.2872 1.86e-36
20 5ncw:A 334 318 0.2293 0.2904 0.3050 5.31e-36 5nct:A
21 4x30:A 372 384 0.2577 0.2930 0.2839 6.28e-36 2ceo:A, 2ceo:B, 2riw:A, 2riw:B, 2xn3:A, 2xn3:B, 2xn5:A, 2xn6:A, 2xn6:B, 2xn7:A, 2xn7:B, 4yia:A, 4yia:B
22 3zha:A 380 380 0.2128 0.2368 0.2368 6.66e-35 4au2:A, 4au2:B, 4au2:D, 4au3:A, 4au3:B, 4au3:C, 4au3:D, 7bdu:A, 7bdu:B, 7bee:A, 7bee:B, 7bfi:A, 7bfi:C, 7bfi:D, 7bfi:B, 3zha:B, 3zha:C, 3zha:D, 3zha:K, 3zha:L, 3zha:P, 3zha:Q
23 2v95:A 342 381 0.2340 0.2895 0.2598 1.61e-30
24 6los:A 369 405 0.2624 0.3008 0.2741 2.67e-29
25 4au2:C 338 380 0.1939 0.2426 0.2158 2.68e-25
26 8h4x:B 32 28 0.0331 0.4375 0.5000 0.008
27 8qqk:B 263 73 0.0520 0.0837 0.3014 0.42 1cyx:A, 1fft:B, 8go3:B, 7n9z:G, 6wti:B, 7xmc:B, 7xmd:B
28 3w6x:A 225 73 0.0567 0.1067 0.3288 0.43 3w6x:B, 3w6x:C, 3w6x:F
29 1as4:B 33 25 0.0284 0.3636 0.4800 0.62
30 6hgi:B 35 31 0.0307 0.3714 0.4194 0.68 6ftp:B, 6hgf:B, 6hgg:B, 6hgj:B, 6hgk:B, 6hgl:B, 5om2:B, 5om3:B, 5om7:B
31 7ohd:B 134 48 0.0402 0.1269 0.3542 1.3
32 2ovq:B 444 58 0.0473 0.0450 0.3448 1.8 2ovr:B, 7t1y:B, 7t1z:B, 5v4b:B
33 5m1k:B 189 29 0.0355 0.0794 0.5172 4.1 5m1n:A, 5m1n:B, 5m1o:A, 5m1o:B, 5m1p:A, 5m1q:A
34 4grs:A 333 39 0.0355 0.0450 0.3846 4.2 4c1k:A, 4c1k:B, 4c1k:C, 4c1k:D, 4c1k:E, 4c1k:F, 4c1l:A, 4c1l:B, 4grs:C, 4grs:B, 4grs:D, 1zco:A, 1zco:B
35 6p8v:G 320 75 0.0449 0.0594 0.2533 4.3 6p80:A, 6u7b:A, 6u7b:C
36 8wfx:A 801 73 0.0496 0.0262 0.2877 7.1
37 8f9x:A 230 45 0.0307 0.0565 0.2889 9.3 8f9x:B, 8f9x:C, 8f9x:D, 8f9x:E, 8f9x:F, 8f9x:G, 8f9x:H, 8f9x:I, 8f9x:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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