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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VDARQRLKEVEVDDNGQFMTTDFGGNIEEQFSLKAGGRGSTLLEDFIFRQKLQHFDHERIPERVVHARGAGAHGIFTSYG
DWSNITAASFLGAKDKQTPVFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIRFPDLIHSVK
PSPDNEVPQAATAHDSAWDFFSSQPSALHTLFWAMSGNGIPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGKAAL
VWEEAQVLAGKNADFHRQDLWDAIESGNAPSWELAVQLIDEDKAQAYGFDLLDPTKFLPEEFAPLQVLGEMTLNRNPMNY
FAETEQISFQPGHIVRGVDFTEDPLLQGRLYSYLDTQLNRHRGPNFEQLPINRPVSGVHNNHRDGQGQAWIHKNIHHYSP
SYLNKGYPAQANQTVGRGFFTTPGRTASGVLNRELSATFDDHYTQPRLFFNSLTPVEQQFVINAIRFEASHVTNEQVKKN
VLEQLNKISNDVAKRVAVALGLEAPQPDPTYYHNNVTRGVSIFNESLPTIATLRVGVLSTTKGGSLDKAKALKEQLEKDG
LKVTVIAEYLASGVDQTYSAADATAFDAVVVAEGAERVFSGKGAMSPLFPAGRPSQILTDGYRWGKPVAAVGSAKKALQS
IGVEEKEAGVYAGAQDEVIKGVEEGLKVFKFLERFAVDGD

The query sequence (length=680) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4aj9:C 682 679 0.9985 0.9956 1.0000 0.0 4aj9:A, 4aj9:B, 4aj9:D, 4bim:A, 4bim:B, 4bim:C, 4bim:D, 3ej6:A, 3ej6:B, 3ej6:C, 3ej6:D, 6nsw:A, 6nsw:B, 6nsw:C, 6nsw:D, 6nsy:A, 6nsy:B, 6nsy:C, 6nsy:D, 6nsz:A, 6nsz:B, 6nsz:C, 6nsz:D, 6nt0:A, 6nt0:B, 6nt0:C, 6nt0:D, 6nt1:A, 6nt1:B, 6nt1:C, 6nt1:D, 3zj4:A, 3zj4:B, 3zj4:C, 3zj4:D, 3zj5:A, 3zj5:B, 3zj5:C, 3zj5:D
2 7wca:B 679 676 0.7074 0.7084 0.7115 0.0 4aue:A, 4aue:B, 4aue:C, 4aue:D, 4aul:A, 4aul:B, 4aul:C, 4aul:D, 4aum:A, 4aum:B, 4aum:C, 4aum:D, 4aun:A, 4aun:B, 4aun:C, 4aun:D, 4aun:E, 4aun:F, 4aun:G, 4aun:H, 4b2y:A, 4b2y:B, 4b2y:C, 4b2y:D, 4b31:A, 4b31:B, 4b31:C, 4b31:D, 4b40:A, 4b40:B, 4b40:C, 4b40:D, 4b5k:A, 4b5k:B, 4b5k:C, 4b5k:D, 4b7a:A, 4b7a:B, 4b7a:C, 4b7a:D, 7vn0:A, 7vn0:B, 7vn0:C, 7vn0:D, 7wca:A, 7wca:C, 7wca:D, 5xvz:A, 5xvz:B, 5xvz:C, 5xvz:D, 5xy4:A, 5xy4:B, 5xy4:C, 5xy4:D, 5xzm:A, 5xzm:B, 5xzm:C, 5xzm:D, 5xzn:A, 5xzn:B, 5xzn:C, 5xzn:D, 5y17:A, 5y17:B, 5y17:C, 5y17:D, 5yem:A, 5yem:B, 5yem:C, 5yem:D, 5zz1:A, 5zz1:B, 5zz1:D, 5zz1:C
3 2iuf:A 688 688 0.6294 0.6221 0.6221 0.0 2iuf:E, 2xf2:A, 2xf2:E
4 5bv2:P 747 664 0.4441 0.4043 0.4548 0.0 4bfl:A, 4bfl:B, 4bfl:C, 4bfl:D, 5bv2:Q, 5bv2:R, 5bv2:S, 6by0:A, 6by0:B, 6by0:C, 6by0:D, 1cf9:A, 1cf9:B, 1cf9:C, 1cf9:D, 4enp:A, 4enp:B, 4enp:C, 4enp:D, 4enq:A, 4enq:B, 4enq:C, 4enq:D, 4enr:A, 4enr:B, 4enr:C, 4enr:D, 4ens:A, 4ens:B, 4ens:C, 4ens:D, 4ent:A, 4ent:B, 4ent:C, 4ent:D, 4enu:A, 4enu:B, 4enu:C, 4enu:D, 4env:A, 4env:B, 4env:C, 4env:D, 4enw:A, 4enw:B, 4enw:C, 4enw:D, 1gg9:A, 1gg9:B, 1gg9:C, 1gg9:D, 1gge:A, 1gge:B, 1gge:C, 1gge:D, 1ggf:A, 1ggf:B, 1ggf:C, 1ggf:D, 1ggh:A, 1ggh:B, 1ggh:C, 1ggh:D, 1ggj:A, 1ggj:B, 1ggj:C, 1ggj:D, 1ggk:A, 1ggk:B, 1ggk:C, 1ggk:D, 1iph:A, 1iph:B, 1iph:C, 1iph:D, 6jqq:A, 6jqq:B, 6jqq:C, 6jqq:D, 1p7y:A, 1p7y:B, 1p7y:C, 1p7y:D, 1p7z:A, 1p7z:B, 1p7z:C, 1p7z:D, 1p80:A, 1p80:B, 1p80:C, 1p80:D, 1p81:A, 1p81:B, 1p81:C, 1p81:D, 3p9p:A, 3p9p:B, 3p9p:C, 3p9p:D, 3p9q:A, 3p9q:B, 3p9q:C, 3p9q:D, 3p9r:A, 3p9r:B, 3p9r:C, 3p9r:D, 3p9s:A, 3p9s:B, 3p9s:C, 3p9s:D, 3pq2:A, 3pq2:B, 3pq2:C, 3pq2:D, 3pq3:A, 3pq3:B, 3pq3:C, 3pq3:D, 3pq4:A, 3pq4:B, 3pq4:C, 3pq4:D, 3pq5:A, 3pq5:B, 3pq5:C, 3pq5:D, 3pq6:A, 3pq6:B, 3pq6:C, 3pq6:D, 3pq7:A, 3pq7:B, 3pq7:C, 3pq7:D, 3pq8:A, 3pq8:B, 3pq8:C, 3pq8:D, 1qf7:A, 1qf7:B, 1qf7:C, 1qf7:D, 1qws:A, 1qws:B, 1qws:C, 1qws:D, 3ttt:A, 3ttt:B, 3ttt:C, 3ttt:D, 3ttu:A, 3ttu:B, 3ttu:C, 3ttu:D, 3ttv:A, 3ttv:B, 3ttv:C, 3ttv:D, 3ttw:A, 3ttw:B, 3ttw:C, 3ttw:D, 3ttx:A, 3ttx:B, 3ttx:C, 3ttx:D, 3vu3:A, 1ye9:A, 1ye9:E, 1ye9:B, 1ye9:F, 1ye9:C, 1ye9:G, 1ye9:D, 1ye9:H, 1ye9:I, 1ye9:M, 1ye9:J, 1ye9:N, 1ye9:K, 1ye9:O, 1ye9:L, 1ye9:P, 6ztv:A, 6ztv:B, 6ztv:C, 6ztv:D, 6ztw:A, 6ztw:B, 6ztw:C, 6ztw:D, 6ztw:E, 6ztw:F, 6ztw:G, 6ztw:H, 6ztx:A, 6ztx:B, 6ztx:C, 6ztx:D
5 8j4q:D 724 657 0.4191 0.3936 0.4338 0.0 8j4q:A, 8j4q:B, 8j4q:C, 8j4r:A, 8j4r:B, 8j4r:C, 8j4r:D, 6lfk:A, 6lfk:B, 6lfk:C, 6lfk:D
6 1sy7:A 698 502 0.3515 0.3424 0.4761 9.90e-164 1sy7:B
7 2a9e:A 491 483 0.3015 0.4175 0.4244 7.09e-122 2a9e:B, 2iqf:A, 2iqf:B, 1qwl:A, 1qwl:B, 1qwm:A, 1qwm:B
8 1si8:A 474 486 0.3059 0.4388 0.4280 7.97e-121 1si8:B, 1si8:C, 1si8:D
9 4qoq:A 481 369 0.2676 0.3784 0.4932 7.39e-118 4qol:A, 4qol:B, 4qol:C, 4qol:D, 4qom:A, 4qom:B, 4qom:C, 4qom:D, 4qon:A, 4qon:B, 4qon:C, 4qon:D, 4qoo:A, 4qoo:B, 4qoo:C, 4qoo:D, 4qop:A, 4qop:B, 4qop:C, 4qop:D, 4qoq:B, 4qoq:C, 4qoq:D, 4qor:A, 4qor:B, 4qor:C, 4qor:D
10 4cab:A 507 378 0.2662 0.3570 0.4788 5.83e-107 4cab:B, 4cab:C, 4cab:D
11 2j2m:A 480 369 0.2559 0.3625 0.4715 7.48e-107 2j2m:B, 2j2m:C, 2j2m:D
12 7p8w:A 502 505 0.2824 0.3825 0.3802 4.77e-106 9bdj:A, 9bdj:B, 9bdj:C, 9bdj:D, 4blc:A, 4blc:B, 4blc:C, 4blc:D, 7cat:A, 7cat:B, 8cat:A, 8cat:B, 1dgb:A, 1dgb:B, 1dgb:C, 1dgb:D, 1dgf:A, 1dgf:B, 1dgf:C, 1dgf:D, 1dgg:A, 1dgg:B, 1dgg:C, 1dgg:D, 1dgh:A, 1dgh:B, 1dgh:C, 1dgh:D, 7di8:A, 7di8:B, 7di8:C, 7di8:D, 8el9:A, 8el9:B, 8el9:C, 8el9:D, 1f4j:A, 1f4j:B, 1f4j:C, 1f4j:D, 5gkn:A, 5gkn:B, 5gkn:C, 5gkn:D, 8hid:A, 8hid:B, 8hid:C, 8hid:D, 3j7b:A, 3j7b:B, 3j7b:C, 3j7b:D, 6jnt:A, 6jnt:B, 6jnt:C, 6jnt:D, 6jnu:A, 6jnu:B, 6jnu:C, 6jnu:D, 3nwl:A, 3nwl:B, 3nwl:C, 3nwl:D, 7p8w:B, 7p8w:C, 7p8w:D, 6pm7:A, 6pm7:B, 6po0:A, 6po0:B, 6po0:C, 6po0:D, 8pvd:A, 1qqw:A, 1qqw:B, 1qqw:C, 1qqw:D, 3re8:A, 3re8:B, 3re8:C, 3re8:D, 3rgp:A, 3rgp:B, 3rgp:C, 3rgp:D, 3rgs:A, 3rgs:B, 3rgs:C, 3rgs:D, 8sgv:B, 8sgv:A, 8sgv:C, 8sgv:D, 1tgu:A, 1tgu:B, 1tgu:C, 1tgu:D, 1th2:A, 1th2:B, 1th2:C, 1th2:D, 1th3:A, 1th3:B, 1th3:C, 1th3:D, 1th4:A, 1th4:B, 1th4:C, 1th4:D, 7vd9:A, 7vd9:B, 7vd9:C, 7vd9:D, 8wzh:B, 8wzh:A, 8wzh:C, 8wzh:D, 8wzj:B, 8wzj:A, 8wzj:C, 8wzj:D, 8wzk:B, 8wzk:A, 8wzk:C, 8wzk:D, 8wzm:B, 8wzm:A, 8wzm:C, 8wzm:D
13 2xq1:B 494 474 0.2750 0.3785 0.3945 2.05e-104 2xq1:C, 2xq1:D, 2xq1:E, 2xq1:F, 2xq1:G, 2xq1:H, 2xq1:I, 2xq1:J, 2xq1:K, 2xq1:L, 2xq1:M, 2xq1:N, 2xq1:O, 2xq1:P
14 1e93:A 476 451 0.2676 0.3824 0.4035 6.41e-104 2cag:A, 2cah:A, 1h6n:A, 1h7k:A, 3hb6:A, 1m85:A, 1mqf:A, 1nm0:A
15 4e37:B 480 478 0.2765 0.3917 0.3933 5.42e-103 4e37:A, 4e37:C, 4e37:D
16 2isa:A 482 352 0.2412 0.3402 0.4659 1.28e-102 2isa:B, 2isa:C, 2isa:D, 2isa:E, 2isa:F, 2isa:G, 2isa:H
17 6pt7:A 500 449 0.2662 0.3620 0.4031 4.35e-102
18 4b7f:A 515 482 0.2750 0.3631 0.3880 1.29e-100 4b7f:B, 4b7f:C, 4b7f:D, 4b7g:A, 4b7g:B, 4b7g:C, 4b7g:D, 4b7h:A, 4b7h:B, 4b7h:C, 4b7h:D
19 1m7s:A 484 417 0.2574 0.3616 0.4197 1.72e-99 1m7s:B, 1m7s:C, 1m7s:D
20 6rjn:A 502 472 0.2618 0.3546 0.3771 3.93e-94 6rjn:B, 6rjn:C, 6rjn:D
21 6rjr:A 505 424 0.2485 0.3347 0.3986 2.07e-90 6rjr:B, 6rjr:C, 6rjr:D
22 1gwe:A 498 360 0.2221 0.3032 0.4194 7.99e-89 1gwf:A, 1gwh:A, 1hbz:A
23 1a4e:A 488 424 0.2397 0.3340 0.3844 8.73e-87 1a4e:B, 1a4e:C, 1a4e:D
24 3e4w:A 303 292 0.1000 0.2244 0.2329 4.93e-14 3e4w:B, 3e4y:A
25 3faw:A 775 129 0.0471 0.0413 0.2481 1.4 3fax:A
26 8t41:A 859 79 0.0338 0.0268 0.2911 2.5
27 2wno:A 119 37 0.0235 0.1345 0.4324 3.0
28 6o9l:Q 430 57 0.0250 0.0395 0.2982 3.3 8bvw:W, 8byq:W, 7eg9:U, 7ega:U, 7egb:U, 7egc:U, 7ena:EA, 7enc:EA, 5gpy:A, 8gxq:EA, 8gxs:EA, 5iy6:Q, 5iy8:Q, 5iy9:Q, 5iya:Q, 5iyb:Q, 5iyc:Q, 5iyd:Q, 7lbm:Q, 7nvr:W, 7nvs:W, 7nvt:W, 7nvu:W, 7nvy:W, 7nvz:W, 7nw0:W, 8s51:W, 8s52:W, 8s54:W, 8s55:W, 8s5n:W, 1vd4:A, 8wak:U, 8wal:U, 8wan:U, 8wao:U, 8wap:U, 8waq:U, 8war:U, 8was:U
29 7oho:AAA 605 88 0.0368 0.0413 0.2841 3.9 6qh5:A, 8t1o:A, 4uqi:A, 2vgl:A
30 2ya1:A 981 139 0.0515 0.0357 0.2518 4.1 2j44:A, 2ya0:A, 2ya2:A
31 7qy5:B 320 71 0.0309 0.0656 0.2958 4.4 7qy5:D
32 7v9o:A 860 45 0.0191 0.0151 0.2889 5.9 7v9n:A, 7v9p:A, 7v9p:B, 7v9q:A
33 1out:A 142 42 0.0235 0.1127 0.3810 6.9 1ouu:A, 1ouu:C
34 8tbx:A 458 57 0.0221 0.0328 0.2632 8.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218