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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHFDKST
SSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDV
PEPYNHVSKYCASLGHKANHSFTPNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVEL
KAFQAT

The query sequence (length=246) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h3i:B 293 227 0.9228 0.7747 1.0000 1.45e-171 5ayf:A, 3cbm:A, 3cbo:A, 3cbp:A, 4e47:A, 4e47:B, 4e47:C, 4e47:D, 5eg2:A, 2f69:A, 4j7f:A, 4j7i:A, 4j83:A, 4j8o:A, 4jds:A, 4jds:B, 4jds:C, 4jds:D, 4jlg:A, 4jlg:B, 3m53:A, 3m54:A, 3m55:A, 3m56:A, 3m57:A, 3m58:A, 3m59:A, 3m5a:A, 1mt6:A, 1n6a:A, 1n6c:A, 1o9s:A, 1o9s:B, 3os5:A, 3vuz:A, 3vv0:A, 1xqh:A, 1xqh:E, 5ylt:A
2 7td5:F 447 210 0.2154 0.1186 0.2524 9.75e-06
3 7td5:A 497 206 0.2114 0.1046 0.2524 1.06e-05
4 7kso:A 395 201 0.2154 0.1342 0.2637 4.87e-05 7ksr:A, 7ktp:A
5 7at8:A 311 126 0.1504 0.1190 0.2937 3.86e-04
6 8t9g:C 536 122 0.1463 0.0672 0.2951 4.70e-04 8fyh:A, 8fyh:G
7 8tas:E 570 122 0.1463 0.0632 0.2951 4.83e-04 8tb9:E
8 5ij7:B 469 122 0.1463 0.0768 0.2951 4.85e-04 6b3w:A, 6b3w:B, 6c23:K, 6c24:K, 5ij7:A, 5ij8:A, 5ij8:B, 4w2r:A, 4w2r:B
9 5hyn:A 581 122 0.1463 0.0620 0.2951 5.41e-04 5hyn:F, 5hyn:K, 5hyn:Q, 5ls6:A, 5ls6:G, 5ls6:J, 5ls6:D
10 6wkr:C 606 122 0.1463 0.0594 0.2951 5.56e-04 4mi0:A, 4mi5:A, 8t9g:I
11 9c8u:A 475 122 0.1463 0.0758 0.2951 5.93e-04
12 5wg6:A 517 122 0.1463 0.0696 0.2951 0.001 5wg6:C
13 7w6l:C 158 134 0.1504 0.2342 0.2761 0.029 5f59:A, 5f6k:C, 5f6k:E, 6kiw:K, 7w6l:E
14 7bre:B 163 135 0.1301 0.1963 0.2370 0.033 7bre:E
15 6nzo:S 233 138 0.1504 0.1588 0.2681 0.11 6px3:S
16 4au7:A 243 41 0.0691 0.0700 0.4146 0.52 4au7:B, 3rq4:A
17 5d6j:A 630 30 0.0488 0.0190 0.4000 2.5 5ey8:A, 5ey8:B, 5ey8:C, 5ey8:D, 5ey8:E, 5ey8:F, 5ey8:G, 5ey8:H, 5icr:A, 5icr:B, 5icr:C, 5icr:D
18 2y2l:B 476 124 0.0976 0.0504 0.1935 2.6 2fff:B, 2jch:A, 2je5:A, 2je5:B, 2xd1:A, 2xd1:B, 2xd5:A, 2xd5:B, 2y2g:A, 2y2g:B, 2y2h:A, 2y2h:B, 2y2i:A, 2y2j:A, 2y2k:A, 2y2l:A, 2y2m:A, 2y2n:A, 2y2o:A, 2y2p:A, 2y2q:A, 2y2q:B, 7zui:AAA, 7zuj:AAA, 7zuk:AAA, 7zul:AAA
19 1cm5:A 759 30 0.0488 0.0158 0.4000 3.4 1cm5:B, 1h16:A, 1h17:A, 1h18:A, 1h18:B, 1mzo:A, 1mzo:B
20 4f3s:A 231 49 0.0691 0.0736 0.3469 3.9 4dz1:A
21 5tfm:A 320 43 0.0569 0.0437 0.3256 5.0 5tfl:A, 5tfl:B
22 8hyk:A 306 47 0.0528 0.0425 0.2766 5.6 7x4p:A
23 5diy:A 463 76 0.0772 0.0410 0.2500 6.0 5diy:B
24 5wfd:B 774 122 0.1220 0.0388 0.2459 9.2 5wfc:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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