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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VCNRLEQILVKTQWAQSYGEAENRAAFSRDLFSELFNIQGSSRALFSGVGVDDMNSAAFTAHCLRVTGALNRLISQLDQQ
ATINADLAHLAGQHASRNLDASNFAAMGQAVMSVVPTHLDCFNQHAWGECYERIASGISG

The query sequence (length=140) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2d2m:A 140 140 1.0000 1.0000 1.0000 2.88e-102 2d2n:A, 7e96:A, 7e97:A, 7e98:A, 7e99:A, 2zfo:A, 2zs0:A, 2zs1:A
2 7vlc:A 146 140 0.4429 0.4247 0.4429 8.88e-39 7vlc:E, 7vld:A, 7vld:E, 7vle:A, 7vle:E, 7vlf:A, 7vlf:E, 3wct:A, 3wct:E, 3wcu:A, 3wcu:E, 3wcv:A, 3wcv:E, 3wcw:A, 3wcw:E
3 1yhu:A 145 140 0.4357 0.4207 0.4357 1.48e-35 1yhu:E, 1yhu:I, 1yhu:M, 1yhu:Q, 1yhu:U
4 2gtl:B 145 140 0.3929 0.3793 0.3929 1.35e-29 2gtl:F, 2gtl:J, 5m3l:B, 5m3l:F, 5m3l:J, 1x9f:B, 1x9f:F, 1x9f:J
5 1yhu:B 144 142 0.3714 0.3611 0.3662 1.86e-29 1yhu:F, 1yhu:J, 1yhu:N, 1yhu:R, 1yhu:V
6 2d2m:B 142 141 0.3929 0.3873 0.3901 2.70e-29 2d2n:B, 7e96:B, 7e97:B, 7e98:B, 7e99:B, 2zfo:B, 2zs0:B, 2zs1:B
7 7vlc:B 144 141 0.3643 0.3542 0.3617 9.20e-29 7vlc:F, 7vld:B, 7vld:F, 7vle:B, 7vle:F, 7vlf:B, 7vlf:F, 3wct:B, 3wct:F, 3wcu:B, 3wcu:F, 3wcv:B, 3wcv:F, 3wcw:B, 3wcw:F
8 4u8u:B 142 140 0.3714 0.3662 0.3714 2.44e-28 4u8u:F, 4u8u:J, 4u8u:Q, 4u8u:U, 4u8u:Y, 4u8u:f, 4u8u:j, 4u8u:n
9 4u8u:D 141 140 0.3357 0.3333 0.3357 1.11e-26 4u8u:H, 4u8u:L, 4u8u:S, 4u8u:W, 4u8u:a, 4u8u:h, 4u8u:l, 4u8u:p, 4wch:D
10 7vlf:D 149 142 0.3714 0.3490 0.3662 1.78e-26 7vlc:D, 7vlc:H, 7vld:D, 7vld:H, 7vle:D, 7vle:H, 7vlf:H, 3wct:D, 3wct:H, 3wcu:D, 3wcu:H, 3wcv:D, 3wcv:H, 3wcw:D, 3wcw:H
11 7e96:C 147 142 0.3714 0.3537 0.3662 2.39e-26 2d2m:C, 2d2n:C, 7e97:C, 7e98:C, 7e99:C, 2zfo:C, 2zs0:C, 2zs1:C
12 1yhu:D 149 137 0.3357 0.3154 0.3431 1.20e-23 1yhu:H, 1yhu:L, 1yhu:P, 1yhu:T, 1yhu:X
13 2gtl:A 147 127 0.3214 0.3061 0.3543 1.87e-23 2gtl:E, 2gtl:I, 5m3l:A, 5m3l:E, 5m3l:I, 1x9f:A, 1x9f:E, 1x9f:I
14 2gtl:D 140 139 0.3500 0.3500 0.3525 9.29e-22 2gtl:H, 2gtl:L, 5m3l:D, 5m3l:H, 5m3l:L, 1x9f:D, 1x9f:H, 1x9f:L
15 7vlf:C 150 137 0.3143 0.2933 0.3212 7.94e-21 7vlc:C, 7vlc:G, 7vld:C, 7vld:G, 7vle:C, 7vle:G, 7vlf:G, 3wct:C, 3wct:G, 3wcu:C, 3wcu:G, 3wcv:C, 3wcv:G, 3wcw:C, 3wcw:G
16 1yhu:C 148 126 0.3143 0.2973 0.3492 1.13e-19 1yhu:G, 1yhu:K, 1yhu:O, 1yhu:S, 1yhu:W
17 4u8u:C 151 147 0.2929 0.2715 0.2789 7.85e-18 4u8u:G, 4u8u:K, 4u8u:R, 4u8u:V, 4u8u:Z, 4u8u:g, 4u8u:k, 4u8u:o
18 4u8u:A 148 134 0.2929 0.2770 0.3060 7.98e-17 4u8u:E, 4u8u:I, 4u8u:P, 4u8u:T, 4u8u:X, 4u8u:e, 4u8u:i, 4u8u:m
19 2gtl:C 149 142 0.2857 0.2685 0.2817 3.76e-15 2gtl:G, 2gtl:K, 5m3l:C, 5m3l:G, 5m3l:K, 1x9f:C, 1x9f:G, 1x9f:K
20 2d2m:D 145 141 0.3071 0.2966 0.3050 4.84e-11 2d2n:D, 7e96:D, 7e97:D, 7e98:D, 7e99:D, 2zfo:D, 2zs0:D, 2zs1:D
21 8oup:B 151 117 0.2071 0.1921 0.2479 0.001 8oup:A, 8oup:C, 8oup:D
22 1f5o:A 149 116 0.1857 0.1745 0.2241 0.006 1f5o:B, 1f5o:C, 1f5o:D, 1f5o:E, 1f5o:F, 1f5p:A, 1f5p:B, 1f5p:C, 1f5p:D, 1f5p:E, 1f5p:F, 2lhb:A, 3lhb:A, 3lhb:B, 3lhb:C, 3lhb:D, 3lhb:E, 3lhb:F, 3lhb:G, 3lhb:H, 3lhb:I, 3lhb:J, 3lhb:K, 3lhb:L, 1uc3:A, 1uc3:B, 1uc3:C, 1uc3:D, 1uc3:E, 1uc3:F, 1uc3:G, 1uc3:H, 1uc3:I, 1uc3:J, 1uc3:K, 1uc3:L
23 1hlb:A 157 134 0.2143 0.1911 0.2239 0.008
24 1v4u:A 143 107 0.1929 0.1888 0.2523 0.038 1v4u:C, 1v4w:A, 1v4w:C, 1v4x:A, 1v4x:C
25 3qqq:A 150 145 0.2143 0.2000 0.2069 0.040 3qqq:B, 3qqr:A, 3qqr:B
26 1cg5:B 141 85 0.1571 0.1560 0.2588 0.046 1cg8:B
27 4h2l:B 146 143 0.2357 0.2260 0.2308 0.088 5ker:D, 5ker:F, 5ker:H, 5ker:B
28 8wix:A 141 110 0.2000 0.1986 0.2545 0.11 8wiy:A, 8wiz:A
29 2dc3:A 172 145 0.2214 0.1802 0.2138 0.38 3ag0:A, 4b3w:A, 4b3w:B, 2dc3:B, 1umo:A, 1umo:B, 1urv:A, 1urv:B, 1ury:A, 1ury:B, 1ut0:A, 1ut0:B, 1ux9:A, 1ux9:B, 1v5h:A
30 3zhw:A 154 129 0.1714 0.1558 0.1860 0.38 3zhw:B
31 2oif:G 154 150 0.2286 0.2078 0.2133 0.49 2oif:A, 2oif:B, 2oif:C, 2oif:D, 2oif:E, 2oif:F, 2oif:H
32 3d1k:B 146 111 0.2000 0.1918 0.2523 0.50 4g51:B, 4g51:D, 3gkv:B, 3gqg:B, 3gqg:D, 2h8d:B, 2h8d:D, 2h8f:B, 2h8f:D, 1hbh:B, 1hbh:D, 4iro:B, 4iro:D, 1la6:B, 5lfg:B, 5lfg:D, 3nfe:B, 3nfe:D, 3ng6:B, 3ng6:D, 4odc:B, 1pbx:B, 2peg:B, 1s5x:B, 1s5y:B, 1s5y:D, 1t1n:B
33 8a3l:u 94 58 0.1357 0.2021 0.3276 1.0 7abz:V, 7ac7:V, 7acj:V, 7acr:V, 5ady:V, 5afi:V, 5aka:V, 8akn:u, 8am9:u, 8ana:u, 8ap4:u, 9ax7:u, 9ax8:V, 8aye:u, 8b0x:u, 7b5k:V, 8b7y:d, 3bbx:V, 8bf7:S, 8bge:S, 8bgh:S, 8bh4:S, 8bhj:S, 8bhl:S, 8bhn:S, 8bhp:S, 8bil:S, 8bim:S, 7bl2:V, 7bl3:V, 7bl4:V, 7bl5:V, 7bl6:V, 6bu8:24, 7bv8:W, 6by1:CV, 6by1:DV, 6c4i:W, 8c8x:V, 8c8y:V, 8c8z:V, 8c90:V, 8c94:V, 8c95:V, 8ceu:u, 8cgd:u, 8cgk:u, 8cgv:u, 9cg5:u, 9cg6:u, 9cg7:u, 7cpj:V, 4csu:W, 1d6k:A, 7d6z:V, 7d80:t, 1dfu:P, 6dnc:Z, 8eiu:u, 8ekc:X, 8emm:u, 6enf:V, 6enj:V, 6enu:V, 9fbv:u, 8fiz:DC, 8fto:u, 8fzd:X, 8fze:X, 8fzf:X, 8fzg:X, 8fzh:X, 8fzi:X, 8fzj:X, 8g2u:V, 8g31:V, 8g34:V, 8g38:V, 8g6w:u, 8g6x:u, 8g6y:u, 8g7p:X, 8g7q:X, 8g7r:X, 8g7s:X, 5gad:W, 5gae:W, 5gaf:W, 5gag:W, 5gah:W, 6gbz:V, 6gc0:V, 6gc4:V, 6gc8:V, 6gwt:V, 6gxm:V, 6gxn:V, 6gxo:V, 6gxp:V, 6h4n:V, 5h5u:W, 6h58:V, 6h58:VV, 6hrm:V, 8hsp:u, 8htz:u, 8hu1:u, 6i0y:8, 6i7v:DW, 6i7v:CW, 8ifb:u, 8ifc:u, 5iqr:V, 5it8:CW, 5it8:DW, 8j1z:u, 2j28:V, 3j5l:V, 5j5b:CW, 5j5b:DW, 3j7z:V, 5j7l:CW, 5j7l:DW, 3j8g:W, 5j88:CW, 5j88:DW, 5j8a:CW, 5j8a:DW, 3j9y:V, 3j9z:LT, 5j91:CW, 5j91:DW, 3ja1:LX, 3jbu:w, 3jbv:w, 3jcd:V, 3jce:V, 3jcj:U, 3jcn:V, 5jc9:CW, 5jc9:DW, 7jss:v, 7jsw:v, 7jsz:v, 5jte:BV, 7jt1:v, 7jt2:v, 7jt3:v, 5ju8:BV, 7k00:u, 7k50:v, 7k51:v, 7k52:v, 7k53:v, 7k54:v, 7k55:v, 5kcr:1Z, 5kcs:1Z, 5kps:V, 5kpv:U, 5kpw:U, 5kpx:U, 5l3p:Z, 6lkq:d, 7lv0:v, 7lvk:d, 5lza:V, 5lzb:V, 5lzc:V, 5lzd:V, 5lze:V, 5lzf:V, 7m5d:V, 5mdv:V, 5mdw:V, 5mdy:V, 5mdz:V, 5mgp:V, 7n1p:LY, 7n2c:LY, 7n2u:LY, 7n2v:LY, 7n30:LY, 7n31:LY, 7nbu:u, 5nco:W, 5np6:t, 7nso:V, 7nsp:V, 7nsq:V, 5nwy:i, 7nwt:V, 7nww:U, 7o19:BV, 7o1a:BV, 7o1c:BV, 5o2r:V, 6o9j:V, 6o9k:V, 6ofx:v, 6og7:v, 6ogf:v, 6ogg:v, 6ogi:v, 7oif:U, 7oig:U, 7oii:U, 7oiz:u, 7oj0:u, 6om6:V, 6ore:V, 6orl:V, 6osk:V, 6osq:V, 6ost:V, 6ot3:V, 7ot5:U, 7otc:V, 6ouo:V, 8p16:V, 8p17:V, 8p18:V, 7p3k:u, 8peg:y, 8phj:u, 6pj6:d, 7pjs:V, 7pjt:V, 7pju:V, 7pjv:V, 7pjw:V, 7pjx:V, 7pjy:V, 7pjz:V, 8pkl:y, 8pva:u, 7q4k:BV, 8q4f:u, 6q97:V, 6q98:V, 6q9a:V, 8qbt:V, 6qdw:w, 7qg8:i, 7qgh:i, 7qgn:i, 7qgr:i, 8qk7:V, 8qoa:u, 7qq3:d, 6qul:W, 8r6c:u, 8r8m:u, 8rpy:V, 8rpz:V, 8rq0:V, 8rq2:V, 6s0k:W, 7s1g:d, 7s1h:d, 7s1i:d, 7s1j:d, 7s1k:d, 7sa4:V, 7ss9:v, 7ssd:v, 7ssl:v, 7ssn:v, 7sso:v, 7ssw:v, 7st2:v, 7st6:v, 7st7:v, 8syl:X, 6szs:V, 8t5d:V, 8t5h:V, 6tbv:L251, 6tc3:L251, 7tos:L25, 4u1u:BV, 4u1u:DV, 4u1v:BV, 4u1v:DV, 4u20:BV, 4u20:DV, 4u24:BV, 4u24:DV, 4u25:BV, 4u25:DV, 4u26:BV, 4u26:DV, 4u27:BV, 4u27:DV, 5u4i:W, 6u48:CW, 5u9f:24, 5u9g:24, 7ug7:LY, 7uph:u, 8upo:4, 8upr:4, 8uql:4, 8uqm:4, 8uqp:4, 8ur0:4, 8urh:4, 8uri:4, 8urx:4, 8ury:4, 4uy8:8, 5uyk:24, 5uyl:24, 5uym:24, 5uyn:24, 5uyp:24, 5uyq:24, 4v4h:BV, 4v4h:DV, 4v4q:BV, 4v4q:DV, 4v4v:BT, 4v4w:BT, 4v50:BV, 4v50:DV, 4v52:BV, 4v52:DV, 4v53:BV, 4v53:DV, 4v54:BV, 4v54:DV, 4v55:BV, 4v55:DV, 4v56:BV, 4v56:DV, 4v57:BV, 4v57:DV, 4v5b:AV, 4v5b:CV, 4v5h:BW, 4v5y:BV, 4v5y:DV, 4v64:BV, 4v64:DV, 4v65:BC, 4v66:BC, 4v69:BV, 4v6c:BV, 4v6c:DV, 4v6d:BV, 4v6d:DV, 4v6e:BV, 4v6e:DV, 4v6k:AW, 4v6l:BW, 4v6m:BV, 4v6n:AX, 4v6o:BX, 4v6p:BX, 4v6q:BX, 4v6r:BX, 4v6s:AX, 4v6t:BV, 4v6v:BZ, 4v6y:BV, 4v6z:BV, 4v70:BV, 4v71:BV, 4v72:BV, 4v73:BV, 4v74:BV, 4v75:BV, 4v76:BV, 4v77:BV, 4v78:BV, 4v79:BV, 4v7a:BV, 4v7b:BV, 4v7c:BX, 4v7d:AY, 4v7i:AV, 4v7s:BV, 4v7s:DV, 4v7t:BV, 4v7t:DV, 4v7u:BV, 4v7u:DV, 4v7v:BV, 4v7v:DV, 4v85:BZ, 4v89:BZ, 4v9c:BV, 4v9c:DV, 4v9d:CV, 4v9d:DV, 4v9o:AV, 4v9o:CV, 4v9o:EV, 4v9o:GV, 4v9p:AV, 4v9p:CV, 4v9p:EV, 4v9p:GV, 8vs9:L25, 8vsa:L25, 6vu3:4, 6vwl:T, 6vwm:T, 6vwn:T, 6vyq:4, 6vyr:4, 6vys:4, 6vyt:4, 6vyu:4, 6vyw:4, 6vyx:4, 6vyy:4, 6vyz:4, 6vz2:4, 6vz3:4, 6vz5:4, 6vz7:4, 6vzj:4, 8w51:W, 5wdt:V, 6wd0:v, 6wd1:v, 6wd2:v, 6wd3:v, 6wd4:v, 6wd5:v, 6wd6:v, 6wd7:v, 6wd8:v, 6wd9:v, 6wda:v, 6wdb:v, 6wdc:v, 6wdd:v, 6wde:v, 6wdf:v, 6wdg:v, 6wdh:v, 6wdi:v, 6wdj:v, 6wdk:v, 6wdl:v, 6wdm:v, 5we4:V, 5we6:V, 4wf1:BV, 4wf1:DV, 5wf0:V, 5wfk:V, 5wfs:V, 6wnt:v, 6wnv:v, 6wnw:v, 4woi:BV, 4woi:CV, 4www:RV, 4www:YV, 6x6t:4, 6x7f:4, 6x7k:4, 6x9q:4, 6xdq:4, 6xdr:4, 6xgf:4, 6xii:4, 6xij:4, 6xz7:V, 6xza:V2, 6xzb:V2, 6y69:V, 7y7c:u, 7y7d:u, 7y7e:u, 7y7f:u, 7y7g:u, 7y7h:u, 4ybb:CW, 4ybb:DW, 7yla:d, 6ys3:w, 6ysr:V, 6yss:V, 6yst:V, 6ysu:V, 7z20:w, 7zod:w, 7zp8:w, 7zq5:w, 7zq6:w, 6ztj:BW, 6ztl:BW, 6ztm:BW, 6ztn:BW, 6zto:BW, 6ztp:BW, 7zta:L251, 6zu1:BW
34 1wmu:B 146 91 0.1500 0.1438 0.2308 1.2 1v75:B, 2z6n:B
35 6djq:B 330 32 0.0714 0.0303 0.3125 1.3
36 4p07:A 570 36 0.1143 0.0281 0.4444 2.5 3elq:A, 3elq:B, 3ets:A, 3ets:B, 3ett:A, 3ett:B, 4p04:B, 4p05:A, 4p05:B, 4p06:A, 4p06:B, 4p07:B
37 6tmf:G 220 28 0.0714 0.0455 0.3571 4.6
38 4z61:A 610 63 0.1143 0.0262 0.2540 4.6 4z5w:B, 4z5w:A, 4z61:B
39 4avd:A 110 85 0.1643 0.2091 0.2706 5.2 4ave:A, 4f68:A, 4f69:A, 4f6b:A, 4f6d:A, 4f6f:A, 4f6g:A, 4f6i:A, 4f6j:A, 1kr7:A, 1v07:A, 2vyy:A, 2vyz:A, 2xkg:A, 2xkh:A, 2xki:A
40 3mkb:A 140 56 0.1071 0.1071 0.2679 5.6 3mkb:C
41 1gcv:A 140 106 0.1714 0.1714 0.2264 5.6 1gcv:C, 1gcw:A, 1gcw:C
42 5ve7:A 282 25 0.0714 0.0355 0.4000 5.8
43 3ak5:A 970 54 0.1143 0.0165 0.2963 6.7 3ak5:B, 3ak5:C, 3ak5:D
44 7r49:H 77 27 0.0786 0.1429 0.4074 7.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218