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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VARSKGYRSKTRKLLEKKVREKGAIPKLSLLMHDYSQGEYVVVKINPSIHKGMPHRRYHGKVGLVVGKRGKAYEVKVNIG
DKERVLIVRPEHLIPFN

The query sequence (length=97) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hku:L21E 97 97 1.0000 1.0000 1.0000 2.38e-65 8hkv:L21E, 8hky:L21E, 8hkz:L21E, 8hl1:L21E, 8hl2:L21E, 8hl3:L21E, 8hl4:L21E, 8hl5:L21E
2 6skf:BU 96 95 0.4124 0.4167 0.4211 3.18e-20 6skg:BU, 6th6:BU, 4v4n:AR, 4v6u:BR
3 6rm3:LT0 159 92 0.4330 0.2642 0.4565 1.96e-16
4 8p5d:LT0 156 62 0.3093 0.1923 0.4839 3.50e-16 8p60:LT0, 8p60:KT0, 7qca:LT0
5 4v3p:LU 164 94 0.4124 0.2439 0.4255 7.77e-16 8ip8:BA, 8ipa:BA, 8ipb:BA, 8jiv:CT, 4v7e:CT
6 6zu5:LT0 160 97 0.3918 0.2375 0.3918 7.64e-15
7 8azw:J 163 92 0.3918 0.2331 0.4130 2.19e-14 8b2l:J3, 7qiw:V, 7qiz:V
8 3cc2:Q 95 90 0.3608 0.3684 0.3889 4.69e-14 3cc4:Q, 3cc7:Q, 3cce:Q, 3ccj:Q, 3ccl:Q, 3ccm:Q, 3ccq:Q, 3ccr:Q, 3ccs:Q, 3ccu:Q, 3ccv:Q, 3cd6:Q, 3cma:Q, 3cme:Q, 3cpw:P, 3cxc:P, 1ffk:N, 3g4s:Q, 3g6e:Q, 3g71:Q, 3i55:Q, 3i56:Q, 1jj2:P, 1k73:R, 1k8a:R, 1k9m:R, 1kc8:R, 1kd1:R, 1kqs:P, 1m1k:R, 1m90:R, 1n8r:R, 1nji:R, 2otj:Q, 2otl:Q, 3ow2:P, 1q7y:R, 1q81:R, 1q82:R, 1q86:R, 2qa4:Q, 2qex:Q, 1qvf:P, 1qvg:P, 1s72:Q, 4v9f:Q, 1vq4:Q, 1vq5:Q, 1vq6:Q, 1vq7:Q, 1vq8:Q, 1vq9:Q, 1vqk:Q, 1vql:Q, 1vqm:Q, 1vqn:Q, 1vqo:Q, 1vqp:Q, 1w2b:P, 1yhq:Q, 1yi2:Q, 1yij:Q, 1yit:Q, 1yj9:Q, 1yjn:Q, 1yjw:Q
9 8c3a:2 159 95 0.3918 0.2390 0.4000 8.65e-14 8c3a:BO, 8cq7:2, 8cq7:BO, 8cqw:2, 8cqw:BO, 8cre:2, 8cre:BO, 8oeq:2, 8oeq:BO, 7pzy:2, 7q08:2, 7q0f:2, 7q0p:2, 7q0r:2, 8q5i:2
10 8br8:LU 157 96 0.3608 0.2229 0.3646 3.34e-13 8brm:LU, 8bsi:LU, 8bsj:LU, 8btd:LU, 8btr:LU, 8fru:T, 7pwg:T, 7pwo:T2
11 8hfr:Tl 160 97 0.3814 0.2313 0.3814 1.15e-12 8aaf:G, 8agt:G, 8agu:G, 8agv:G, 8agw:G, 8agx:G, 8agz:G, 5apn:T, 5apo:T, 7azy:u, 7b7d:Lp, 8bip:LT, 8bjq:LT, 8bn3:N1, 8bqd:BJ, 8bqx:BJ, 7bt6:T, 7btb:T, 8ccs:F, 8cdl:F, 8cdr:F, 8ceh:F, 8cf5:F, 8cg8:F, 8cgn:F, 8civ:F, 8cku:F, 8cmj:F, 5dat:N1, 5dat:n1, 5dc3:N1, 5dc3:n1, 5dge:N1, 5dge:n1, 5dgf:N1, 5dgf:n1, 5dgv:N1, 5dgv:n1, 6elz:T, 8eub:AT, 8evp:AT, 8evq:AT, 8evr:AT, 8evs:AT, 8evt:AT, 8ewb:AT, 8ewc:AT, 5fci:N1, 5fci:n1, 5fcj:N1, 5fcj:n1, 6ft6:T, 5gak:V, 6gq1:T, 6gqb:T, 6gqv:T, 5h4p:T, 6hd7:V, 6hhq:2, 6hhq:CV, 5i4l:N1, 5i4l:n1, 6i7o:BJ, 6i7o:YJ, 5it7:TT, 3j6x:61, 3j6y:61, 3j77:71, 3j78:71, 3jct:T, 5jcs:T, 5juo:Y, 5jup:Y, 5jus:Y, 5jut:Y, 5juu:Y, 8k2d:LT, 8k82:LT, 5lyb:N1, 5lyb:n1, 5m1j:T5, 6m62:T, 5mc6:BJ, 5mei:2, 5mei:CV, 7mpi:AT, 7mpj:AT, 6n8j:T, 6n8k:T, 6n8l:T, 6n8m:g, 6n8n:g, 6n8o:g, 7n8b:AT, 7nac:T, 5ndg:N1, 5ndg:n1, 5ndv:N1, 5ndv:n1, 5ndw:N1, 5ndw:n1, 7nrc:LV, 7nrd:LV, 5obm:N1, 5obm:n1, 7of1:T, 7oh3:T, 7ohq:T, 7oht:T, 6oig:T, 5on6:2, 5on6:CV, 7osa:eL21, 7osm:eL21, 8p8m:QT, 8p8n:QT, 8p8u:QT, 8pfr:QT, 6q8y:BJ, 6qik:T, 6qt0:T, 6qtz:T, 7r7a:T, 6r84:V, 6r86:V, 6r87:V, 6ri5:T, 7rr5:LT, 6rzz:T, 6s05:T, 6s47:AV, 6snt:z, 6sv4:BJ, 6sv4:YJ, 6sv4:ZJ, 6t4q:LT, 5t62:g, 5t6r:g, 6t7i:LT, 6t7t:LT, 6t83:Ty, 6t83:E, 5tbw:2, 5tbw:CV, 6tb3:BJ, 5tga:N1, 5tga:n1, 5tgm:N1, 5tgm:n1, 6tnu:BJ, 7too:AL21, 7top:AL21, 4u3m:N1, 4u3m:n1, 4u3n:N1, 4u3n:n1, 4u3u:N1, 4u3u:n1, 4u4n:N1, 4u4n:n1, 4u4o:N1, 4u4o:n1, 4u4q:N1, 4u4q:n1, 4u4r:N1, 4u4r:n1, 4u4u:N1, 4u4u:n1, 4u4y:N1, 4u4y:n1, 4u4z:N1, 4u4z:n1, 4u50:N1, 4u50:n1, 4u51:N1, 4u51:n1, 4u52:N1, 4u52:n1, 4u53:N1, 4u53:n1, 4u55:N1, 4u55:n1, 4u56:N1, 4u56:n1, 4u6f:N1, 4u6f:n1, 7ug6:T, 7uoo:T, 7uqb:T, 7uqz:T, 6uz7:AT, 7v08:T, 4v4b:BQ, 4v6i:BU, 4v7f:T, 4v7h:BQ, 4v7r:BT, 4v7r:DT, 4v88:BT, 4v88:DT, 4v8t:T, 4v8y:BT, 4v8z:BT, 4v91:T, 6woo:T, 6xiq:T, 6xir:T, 8y0u:LT, 6ylg:T, 6ylh:T, 6ylx:T, 6yly:T, 7z34:T, 6z6j:LT, 6z6k:LT, 7zpq:BS, 7zrs:BS, 7zs5:BU, 7zuw:BS, 7zux:ES, 7zw0:LW
12 5t5h:U 126 94 0.3402 0.2619 0.3511 5.11e-12
13 4v8m:BU 158 94 0.3299 0.2025 0.3404 1.12e-11 8ova:BU, 8ove:BU
14 8rxh:LS 158 94 0.3505 0.2152 0.3617 1.26e-11 8a3w:S, 8a98:S, 6az3:S, 3jcs:S, 8ovj:S, 8rxx:LS, 5t2a:S
15 5xy3:T 158 96 0.3402 0.2089 0.3438 3.53e-11
16 8eui:T 159 62 0.2784 0.1698 0.4355 5.78e-11 8eug:T
17 5xxb:S 154 94 0.3505 0.2208 0.3617 6.93e-11
18 7olc:LT 158 62 0.2784 0.1709 0.4355 2.04e-10 8i9p:LT, 8i9r:LT, 8i9t:LT, 8i9v:LT, 8i9w:LT, 8i9x:LT, 8i9y:LT, 8i9z:LT, 8ia0:LT, 7old:LT, 8oo0:LT, 8pv1:LT, 8pv2:LT, 8pv3:LT, 8pv4:LT, 8pv5:LT, 8pv6:LT, 8pv7:LT, 8pv8:LT, 8pvk:LT, 8pvl:LT, 7z3n:LT, 7z3o:LT
19 7qep:N1 159 102 0.3918 0.2390 0.3725 3.30e-10
20 4v8p:BP 156 98 0.3814 0.2372 0.3776 5.93e-10 4v8p:CP, 4v8p:EP, 4v8p:GP
21 7oya:T1 157 94 0.3711 0.2293 0.3830 6.35e-10 7oyb:T1
22 7oyc:T1 157 94 0.3608 0.2229 0.3723 9.48e-10
23 7r81:V1 159 62 0.2577 0.1572 0.4032 1.16e-09
24 4v6w:CT 158 94 0.3505 0.2152 0.3617 2.43e-09 6xu6:CT, 6xu7:CT, 6xu8:CT
25 7cpu:LT 160 97 0.3505 0.2125 0.3505 4.45e-09 7a01:72, 8a3d:N, 5aj0:AT, 8b5l:T, 8b6c:T, 9bdl:AL21, 9bdn:AL21, 9bdp:AL21, 7bhp:LT, 8bhf:G1, 8bpo:S2, 8btk:BT, 7cpv:LT, 4d5y:T, 4d67:T, 6d90:T, 6d9j:T, 9f1b:BT, 9f1c:BT, 9f1d:BT, 7f5s:LT, 8fkp:LE, 8fkq:LE, 8fkr:LE, 8fks:LE, 8fkt:LE, 8fku:LE, 8fkv:LE, 8fkw:LE, 8fkx:LE, 8fky:LE, 8fkz:LE, 8fl0:LE, 8fl2:LE, 8fl3:LE, 8fl4:LE, 8fl6:LE, 8fl7:LE, 8fl9:LE, 8fla:LE, 8flb:LE, 8flc:LE, 8fld:LE, 8fle:LE, 8flf:LE, 6frk:T, 6ftg:T, 6fti:T, 6ftj:T, 8g5y:LT, 8g5z:LT, 8g60:LT, 8g61:LT, 8g6j:LT, 8glp:LT, 6gz3:AT, 6gz4:AT, 6gz5:AT, 6hcf:T3, 6hcj:T3, 6hcm:T3, 6hcq:T3, 8idt:c, 8idy:c, 8ie3:c, 8ifd:2N, 8ife:2N, 8ine:c, 8inf:c, 8ink:T, 6ip5:2N, 6ip6:2N, 6ip8:2N, 8ipd:T, 8ipx:T, 8ipy:T, 8ir1:c, 8ir3:c, 3j7o:T, 3j7p:T, 3j7q:T, 3j7r:T, 3j92:T, 3jag:T, 3jah:T, 3jai:T, 3jaj:T, 3jan:T, 8jdj:Y, 8jdk:Y, 8jdl:Y, 8jdm:Y, 8k2c:LT, 5lks:LT, 6lqm:c, 6lsr:c, 6lss:c, 7ls1:N2, 7ls2:N2, 6lu8:c, 5lzs:T, 5lzt:T, 5lzu:T, 5lzv:T, 5lzw:T, 5lzx:T, 5lzy:T, 5lzz:T, 7mdz:T, 6mtb:T, 6mtc:T, 6mtd:T, 6mte:T, 7nfx:T, 7nwg:T3, 7nwh:T, 7nwi:T, 7o7y:BT, 7o7z:BT, 7o80:BT, 7o81:BT, 7obr:T, 8ohd:LT, 8oj0:LT, 8oj5:LT, 8oj8:LT, 6ole:U, 6olf:U, 6olg:AT, 6oli:U, 6olz:AT, 6om0:U, 6om7:U, 7ow7:N, 7oyd:T, 8p2k:BT, 6p5i:AT, 6p5j:AT, 6p5k:AT, 6p5n:AT, 8q7z:BT, 8q87:BT, 8qfd:T, 7qgg:U, 8qoi:LT, 7qvp:LT, 7qvp:MT, 7qwq:T, 7qwr:T, 7qws:T, 6qzp:LT, 6r5q:T, 6r6g:T, 6r6p:T, 6r7q:T, 8rjb:T, 8rjc:T, 8rjd:T, 8scb:T, 6sgc:T2, 6swa:R, 5t2c:N, 6t59:T3, 7tm3:T, 7toq:AL21, 7tor:AL21, 7tut:T, 7ucj:T, 7uck:T, 4ug0:LT, 4ujc:BT, 4ujd:AT, 4uje:CT, 4v5z:Bq, 4v6x:CT, 6w6l:U, 6xa1:LT, 7xnx:LT, 7xny:LT, 8xsx:LT, 8xsy:LT, 8xsz:LT, 6y0g:LT, 8y0w:LT, 8y0x:LT, 6y2l:LT, 6y57:LT, 6y6x:LT, 8yoo:LT, 8yop:LT, 6z6l:LT, 6z6m:LT, 6z6n:LT, 7zjw:LW, 7zjx:LW, 6zm7:LT, 6zme:LT, 6zmi:LT, 6zmo:LT, 6zvk:72
26 6zj3:Lh 158 94 0.3402 0.2089 0.3511 5.01e-08
27 9bh5:CT 160 96 0.3196 0.1938 0.3229 2.01e-07 9cai:CT
28 3j79:V 155 95 0.3196 0.2000 0.3263 1.55e-05 3jbn:AV, 3jbo:AV, 3jbp:AV, 8tpu:AV, 5umd:V
29 5zji:F 158 51 0.1753 0.1076 0.3333 0.084
30 5l8r:F 154 51 0.1753 0.1104 0.3333 1.7 7dkz:F, 4rku:F, 4y28:F, 6yac:F, 6yez:F, 6zoo:F, 6zxs:F
31 7mq8:SP 1993 46 0.1443 0.0070 0.3043 2.7 7mq9:SP
32 8bcv:F 158 51 0.1546 0.0949 0.2941 2.8 7ew6:F, 7ewk:F, 7f9o:F, 7f9o:j
33 7mqa:SP 2485 46 0.1443 0.0056 0.3043 2.8
34 8c9e:A 921 29 0.1134 0.0119 0.3793 3.7 8c9f:A, 8c9g:A, 8c9g:B
35 5y2f:A 297 69 0.1959 0.0640 0.2754 3.9 8ak5:A, 8ak5:B, 8ak6:A, 8ak6:B, 8ak7:A, 8ak7:B, 8ak8:A, 8ak8:B, 8ak9:A, 8ak9:B, 8aka:A, 8aka:B, 8akb:A, 8akb:B, 8akc:A, 8akc:B, 8akd:A, 8akd:B, 8ake:A, 8ake:B, 8akf:A, 8akf:B, 8akg:A, 8akg:B, 8bl0:A, 8bl0:B, 8bl1:A, 8bl1:B, 7cl0:A, 7cl1:A, 8cnm:A, 8cnm:B, 8cno:A, 8cno:B, 8f86:K, 8g57:K, 9g7h:A, 9g7h:B, 6hoy:A, 6hoy:B, 8i2b:A, 8i2b:B, 3k35:A, 3k35:B, 3k35:C, 3k35:D, 3k35:E, 3k35:F, 5mf6:A, 5mf6:B, 5mfp:A, 5mfp:B, 5mfz:A, 5mfz:B, 5mgn:A, 5mgn:B, 3pki:A, 3pki:B, 3pki:C, 3pki:D, 3pki:E, 3pki:F, 3pkj:A, 3pkj:B, 3pkj:C, 3pkj:D, 3pkj:E, 3pkj:F, 6qcd:A, 6qcd:B, 6qce:A, 6qce:B, 6qch:A, 6qch:B, 6qcj:A, 6qcj:B, 5x16:A, 6xuy:A, 6xuy:B, 6xv1:A, 6xv1:B, 6xv6:A, 6xv6:B, 6xv6:C, 6xv6:D, 6xv6:E, 6xv6:F, 6xvg:A, 6xvg:B, 6xvg:C, 6xvg:D, 6xvg:E, 6xvg:F, 3zg6:A, 6zu4:A, 6zu4:B
36 6ly5:f 162 51 0.1546 0.0926 0.2941 5.1 3lw5:F, 2o01:F, 2wsc:F, 2wse:F, 2wsf:F, 4xk8:F, 4xk8:f
37 6igz:F 163 53 0.1340 0.0798 0.2453 6.9
38 7w86:A 117 37 0.1443 0.1197 0.3784 7.1
39 5n6u:A 811 37 0.1546 0.0185 0.4054 8.4 5n6u:B, 5n6u:C, 5n6u:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218