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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VAFRFHQYQVVGRALPTPGDEQPKIYRMKLWATNEVRAKSKFWYFLRKLKKVKKSNGQMLAINEIFEKNPTTIKNYGIWL
RYQSRTGYHNMYKEYRDTTLNGAVEQMYTEMASRHRVRSPCIQIIKTATVNFKLCKRDNTKQFHNSKIKFPLVYQKVRPP
TRKLKTTYKATRPNLFM

The query sequence (length=177) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ip8:YA 177 177 1.0000 1.0000 1.0000 1.37e-133 8ipa:YA, 8ipb:YA, 8jiv:CS, 4v3p:LS, 4v6i:BS, 4v7e:CS
2 8azw:I 177 177 0.8927 0.8927 0.8927 5.73e-119 8b2l:I3, 7qiw:U, 7qiz:U
3 8a3d:M 176 170 0.4972 0.5000 0.5176 3.28e-62 7a01:62, 5aj0:AS, 8b5l:S, 8b6c:S, 9bdl:AL20, 9bdn:AL20, 9bdp:AL20, 7bhp:LS, 8bhf:F1, 8bpo:R2, 8btk:BS, 7cpu:LS, 7cpv:LS, 4d5y:S, 4d67:S, 6d90:S, 6d9j:S, 9f1b:BS, 9f1c:BS, 9f1d:BS, 7f5s:LS, 8fkp:LC, 8fkq:LC, 8fkr:LC, 8fks:LC, 8fkt:LC, 8fku:LC, 8fkv:LC, 8fkw:LC, 8fkx:LC, 8fky:LC, 8fkz:LC, 8fl0:LC, 8fl2:LC, 8fl3:LC, 8fl4:LC, 8fl6:LC, 8fl7:LC, 8fl9:LC, 8fla:LC, 8flb:LC, 8flc:LC, 8fld:LC, 8fle:LC, 8flf:LC, 6frk:S, 6ftg:S, 6fti:S, 6ftj:S, 8g5y:LS, 8g5z:LS, 8g60:LS, 8g61:LS, 8g6j:LS, 8glp:LS, 6gz3:AS, 6gz4:AS, 6gz5:AS, 6hcf:S3, 6hcj:S3, 6hcm:S3, 6hcq:S3, 8idt:b, 8idy:b, 8ie3:b, 8ifd:2M, 8ife:2M, 8ine:b, 8inf:b, 8ink:b, 6ip5:2M, 6ip6:2M, 6ip8:2M, 8ipd:b, 8ipx:b, 8ipy:b, 8ir1:b, 8ir3:b, 3j7o:S, 3j7p:S, 3j7q:S, 3j7r:S, 3j92:S, 3jag:S, 3jah:S, 3jai:S, 3jaj:S, 3jan:S, 8jdj:X, 8jdk:X, 8jdl:X, 8jdm:X, 8k2c:LS, 5lks:LS, 6lqm:b, 6lsr:b, 6lss:b, 7ls1:M2, 7ls2:M2, 6lu8:b, 5lzs:S, 5lzt:S, 5lzu:S, 5lzv:S, 5lzw:S, 5lzx:S, 5lzy:S, 5lzz:S, 7mdz:S, 6mtb:S, 6mtc:S, 6mtd:S, 6mte:S, 7nfx:S, 7nwg:S3, 7nwh:S, 7nwi:S, 7o7y:BS, 7o7z:BS, 7o80:BS, 7o81:BS, 7obr:S, 8ohd:LS, 8oj0:LS, 8oj5:LS, 8oj8:LS, 6ole:T, 6olf:T, 6olg:AS, 6oli:T, 6olz:AS, 6om0:T, 6om7:T, 7ow7:M, 7oya:S1, 7oyb:S1, 7oyc:S1, 7oyd:S, 8p2k:BS, 8q7z:BS, 8q87:BS, 8qfd:S, 7qgg:T, 8qoi:LS, 7qvp:LS, 7qvp:MS, 7qwq:S, 7qwr:S, 7qws:S, 6qzp:LS, 6r5q:S, 6r6g:S, 6r6p:S, 6r7q:S, 8rjb:S, 8rjc:S, 8rjd:S, 8scb:S, 6sgc:S2, 6swa:Q, 5t2c:M, 6t59:S3, 7tm3:S, 7toq:AL20, 7tor:AL20, 7tut:S, 7ucj:S, 7uck:S, 4ug0:LS, 4ujc:BS, 4ujd:AS, 4uje:CS, 4v6x:CS, 6w6l:T, 6xa1:LS, 7xnx:LS, 7xny:LS, 8xsx:LS, 8xsy:LS, 8xsz:LS, 6y0g:LS, 8y0w:LS, 8y0x:LS, 6y2l:LS, 6y57:LS, 6y6x:LS, 8yoo:LS, 8yop:LS, 6z6l:LS, 6z6m:LS, 6z6n:LS, 6zm7:LS, 6zme:LS, 6zmi:LS, 6zmo:LS, 6zvk:62
4 6p5i:AS 176 170 0.4689 0.4716 0.4882 1.18e-58 6p5j:AS, 6p5k:AS, 6p5n:AS, 7zjw:LV, 7zjx:LV
5 4v8p:AX 188 174 0.4915 0.4628 0.5000 3.48e-58 4v8p:DX, 4v8p:FX, 4v8p:HX
6 9bh5:CS 179 148 0.4463 0.4413 0.5338 4.01e-58 9cai:CS
7 4v6w:CS 173 158 0.4576 0.4682 0.5127 6.67e-58 6xu6:CS, 6xu7:CS, 6xu8:CS
8 5xxb:R 182 174 0.5028 0.4890 0.5115 1.84e-57
9 8i9p:LS 174 174 0.4859 0.4943 0.4943 9.79e-56 8i9r:LS, 8i9t:LS, 8i9v:LS, 8i9w:LS, 8i9x:LS, 8i9y:LS, 8i9z:LS, 8ia0:LS, 7olc:LS, 7old:LS, 8oo0:LS, 8pv1:LS, 8pv2:LS, 8pv3:LS, 8pv4:LS, 8pv5:LS, 8pv6:LS, 8pv7:LS, 8pv8:LS, 8pvk:LS, 8pvl:LS, 7z3n:LS, 7z3o:LS
10 7pzy:0 171 174 0.4746 0.4912 0.4828 9.94e-55 8c3a:0, 8c3a:BN, 8cq7:0, 8cq7:BN, 8cqw:0, 8cqw:BN, 8cre:0, 8cre:BN, 8oeq:0, 8oeq:BN, 7q08:0, 7q0f:0, 7q0p:0, 7q0r:0, 8q5i:0
11 7azy:s 172 173 0.4633 0.4767 0.4740 2.54e-54 8aaf:F, 8agt:F, 8agu:F, 8agv:F, 8agw:F, 8agx:F, 8agz:F, 5apn:S, 5apo:S, 7b7d:Lo, 8bip:LS, 8bjq:LS, 8bn3:N0, 8bqd:BH, 8bqx:BH, 7bt6:S, 7btb:S, 6c0f:S, 6cb1:S, 8ccs:E, 8cdl:E, 8cdr:E, 8ceh:E, 8cf5:E, 8cg8:E, 8cgn:E, 8civ:E, 8cku:E, 8cmj:E, 5dat:N0, 5dat:n0, 5dc3:N0, 5dc3:n0, 5dge:N0, 5dge:n0, 5dgf:N0, 5dgf:n0, 5dgv:N0, 5dgv:n0, 8e5t:S, 6elz:S, 6em1:S, 6em4:S, 6em5:S, 8eub:AS, 8evp:AS, 8evq:AS, 8evr:AS, 8evs:AS, 8evt:AS, 8ewb:AS, 8ewc:AS, 5fci:N0, 5fci:n0, 5fcj:N0, 5fcj:n0, 6ft6:S, 5gak:U, 6gq1:S, 6gqb:S, 6gqv:S, 5h4p:S, 6hd7:U, 8hfr:SZ, 6hhq:0, 6hhq:CU, 5i4l:N0, 5i4l:n0, 6i7o:BH, 6i7o:YH, 5it7:SS, 3j6x:60, 3j6y:60, 3j77:70, 3j78:70, 3jct:S, 5jcs:S, 5juo:X, 5jup:X, 5jus:X, 5jut:X, 5juu:X, 8k2d:LS, 8k82:LS, 5lyb:N0, 5lyb:n0, 5m1j:S5, 6m62:S, 5mc6:BH, 5mei:0, 5mei:CU, 7mpi:AS, 7mpj:AS, 6n8j:S, 6n8k:S, 6n8l:S, 6n8m:f, 6n8n:f, 6n8o:f, 7n8b:AS, 7nac:S, 5ndg:N0, 5ndg:n0, 5ndv:N0, 5ndv:n0, 5ndw:N0, 5ndw:n0, 7nrc:LU, 7nrd:LU, 5obm:N0, 5obm:n0, 7of1:S, 7oh3:S, 7ohp:S, 7ohq:S, 7ohr:S, 7ohs:S, 7oht:S, 7ohu:S, 7ohv:S, 7ohw:S, 7ohx:S, 7ohy:S, 6oig:S, 5on6:0, 5on6:CU, 7osa:eL20, 7osm:eL20, 8p8m:QS, 8p8n:QS, 8p8u:QS, 8pfr:QS, 6q8y:BH, 6qik:S, 6qt0:S, 6qtz:S, 7r7a:S, 6r84:U, 6r86:U, 6r87:U, 6ri5:S, 7rr5:LS, 6rzz:S, 6s05:S, 6s47:AU, 6snt:y, 6sv4:BH, 6sv4:YH, 6sv4:ZH, 6t4q:LS, 5t62:f, 5t6r:f, 6t7i:LS, 6t7t:LS, 6t83:Sy, 6t83:D, 5tbw:0, 5tbw:CU, 6tb3:BH, 5tga:N0, 5tga:n0, 5tgm:N0, 5tgm:n0, 6tnu:BH, 7too:AL20, 7top:AL20, 7u0h:S, 4u3m:N0, 4u3m:n0, 4u3n:N0, 4u3n:n0, 4u3u:N0, 4u3u:n0, 4u4n:N0, 4u4n:n0, 4u4o:N0, 4u4o:n0, 4u4q:N0, 4u4q:n0, 4u4r:N0, 4u4r:n0, 4u4u:N0, 4u4u:n0, 4u4y:N0, 4u4y:n0, 4u4z:N0, 4u4z:n0, 4u50:N0, 4u50:n0, 4u51:N0, 4u51:n0, 4u52:N0, 4u52:n0, 4u53:N0, 4u53:n0, 4u55:N0, 4u55:n0, 4u56:N0, 4u56:n0, 4u6f:N0, 4u6f:n0, 7ug6:S, 7uoo:S, 7uqb:S, 7uqz:S, 7v08:S, 4v88:BS, 4v88:DS, 4v8t:S, 4v8y:BS, 4v8z:BS, 8v83:S, 8v84:S, 8v87:S, 4v91:S, 6woo:S, 6xiq:S, 6xir:S, 8y0u:LS, 6ylg:S, 6ylh:S, 6ylx:S, 6yly:S, 5z3g:W, 7z34:S, 6z6j:LS, 6z6k:LS, 7zpq:BR, 7zrs:BR, 7zs5:BT, 7zuw:BR, 7zux:ER, 7zw0:LV
12 6uz7:AS 169 171 0.4576 0.4793 0.4737 1.90e-53
13 8etg:S 174 171 0.4689 0.4770 0.4854 5.03e-53 8esq:S, 8esr:S, 8etc:S, 8eth:S, 8eti:S, 8etj:S, 8eug:S, 8eui:S, 8eup:S, 8euy:S, 8ev3:S
14 3j79:U 180 150 0.4294 0.4222 0.5067 1.45e-52 3jbn:AU, 3jbo:AU, 3jbp:AU, 8tpu:AU, 5umd:U
15 6zj3:Lg 181 173 0.4802 0.4696 0.4913 6.30e-52
16 7r81:U1 173 174 0.4576 0.4682 0.4655 8.31e-52
17 5xy3:S 175 169 0.4124 0.4171 0.4320 1.61e-48
18 8fru:S 173 145 0.3446 0.3526 0.4207 1.60e-37 8br8:LT, 8brm:LT, 8bsi:LT, 8bsj:LT, 8btd:LT, 8btr:LT, 7pwg:S, 7pwo:S2
19 4v8m:BS 179 155 0.3220 0.3184 0.3677 1.14e-31 8ova:BS, 8ove:BS, 5t5h:S
20 8a3w:R 178 163 0.3164 0.3146 0.3436 5.12e-28 8a98:R, 6az3:R, 3jcs:R, 8ovj:R, 8rxh:LR, 8rxx:LR, 5t2a:Q
21 6zu5:LS0 169 152 0.2938 0.3077 0.3421 2.04e-26
22 7qep:N0 178 146 0.2655 0.2640 0.3219 1.66e-25
23 6rm3:LS0 179 148 0.2542 0.2514 0.3041 6.93e-19
24 8p5d:LS0 170 148 0.2712 0.2824 0.3243 1.95e-16 8p60:LS0, 8p60:KS0, 7qca:LS0
25 7d9f:A 591 60 0.1243 0.0372 0.3667 1.1 7d9f:B, 7d9g:A, 7d9g:B, 7d9h:A, 7d9h:B, 7d9i:A, 7d9i:B, 7d9j:A, 7d9j:B
26 1h3d:A 288 50 0.0904 0.0556 0.3200 1.4 1q1k:A
27 6xyw:Ay 111 59 0.1073 0.1712 0.3220 3.5
28 7mfp:B 354 64 0.0847 0.0424 0.2344 9.6 7mfo:A, 7mfo:B, 7mfo:C, 7mfo:D, 7mfo:E, 7mfo:F, 7mfo:G, 7mfo:H, 7mfo:I, 7mfo:J, 7mfp:A, 7mfp:C, 7mfp:D, 7mfq:A, 7mfq:B, 7mfq:C, 7mfq:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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