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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TYQERADELVVKIKDMFNALGDGDISPSAYDTAWVARLATISSDGSEKPRFPQALNWVFNNQLQDGSWGIESHFSLCDRL
LNTTNSVIALSVWKTGHSQVQQGAEFIAENLRLLNEEDELSPDFQIIFPALLQKAKALGINLPYDLPFIKYLSTTREARL
TDVSAAADNIPANMLNALEGLEEVIDWNKIMRFQSKDGSFLSSPASTACVLMNTGDEKCFTFLNNLLDKFGGCVPCMYSI
DLLERLSLVDNIEHLGIGRHFKQEIKGALDYVYRHWSERGIGWGRDSLVPDLNTTALGLRTLRMHGYNVSSDVLNNFKDE
NGRFFSSAGQTHVELRSVVNLFRASDLAFPDERAMDDARKFAEPYLREALATKISTNTKLFKEIEYVVEYPWHMSIPRLE
ARSYIDSYDDNYVWQRKTLYRMPSLSNSKCLELAKLDFNIVQSLHQEELKLLTRWWKESGMADINRVAEVYFSSATFEPE
YSATRIAFTKIGCLQVLFDDMADIFATLDELKSFTEGVKRWDTSLLHEIPECMQTCFKVWFKLMEEVNNDVVKVQGRDML
AHIRKPWELYFNCYVQEREWLEAGYIPTFEEYLKTYAISVGLGPCTLQPILLMGELVKDDVVEKVHYPSNMFELVSLSWR
LTNDTKTYQAEKARGQQASGIACYMKDNPGATEEDAIKHICRVVDRALKEASFEYFKPSNDIPMGCKSFIFNLRLCVQIF
YKEIKDYIRKVYIDPIQV

The query sequence (length=738) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3p5r:A 750 750 0.9973 0.9813 0.9813 0.0 3p5p:A, 3p5r:B
2 3sae:A 780 768 0.5081 0.4808 0.4883 0.0 3sdr:A, 3sdt:A, 3sdu:A, 3sdv:A
3 7y47:B 767 735 0.3726 0.3585 0.3741 4.78e-162
4 3pya:A 688 502 0.2873 0.3081 0.4223 1.47e-124 4lix:A, 3pyb:A
5 8ih5:A 689 505 0.2507 0.2685 0.3663 9.66e-103 8ih5:F, 8ih5:B, 8ih5:C, 8ih5:D, 8ih5:E
6 3n0g:B 524 463 0.2019 0.2844 0.3218 2.05e-70 3n0g:A
7 7xkw:A 499 502 0.2127 0.3146 0.3127 1.42e-66
8 2ong:A 543 478 0.2005 0.2726 0.3096 4.78e-64 2ong:B, 2onh:A, 2onh:B
9 5dhi:A 536 519 0.1965 0.2705 0.2794 1.07e-60 5dhk:A, 4di5:A, 5eas:A, 5eat:A, 5eau:A, 1hx9:A, 1hxa:A, 1hxc:A, 1hxg:A, 5ik0:A, 5ik6:A, 5ik9:A, 5ika:A, 5ikh:A, 5il3:A, 5il8:A, 5ild:A, 5ilh:A, 5ili:A, 5ily:A, 3lz9:A, 3m00:A, 3m01:A, 3m02:A, 4rnq:A
10 1n1z:A 537 458 0.2033 0.2793 0.3275 2.15e-60 1n1b:A, 1n1b:B, 1n1z:B, 1n20:A, 1n20:B, 1n21:A, 1n22:A, 1n22:B, 1n23:A, 1n23:B, 1n24:A, 1n24:B
11 3g4f:A 515 506 0.2019 0.2893 0.2945 3.65e-60 3g4f:B
12 5uv2:A 514 495 0.2005 0.2879 0.2990 4.42e-60 6onm:A, 5uv1:A
13 6a1i:A 522 511 0.2033 0.2874 0.2935 2.02e-51 6a1d:A, 6a1e:A, 6a3x:A, 7e9r:B, 7e9r:C, 6k16:A, 6o9p:A
14 7bzc:A 535 514 0.1856 0.2561 0.2665 3.89e-51 7bzb:A
15 6a2d:A 519 511 0.1978 0.2813 0.2857 7.83e-51 6a2c:A, 6a2c:B, 6a2d:B
16 8uat:F 351 94 0.0312 0.0655 0.2447 0.47 3hf3:A, 3hf3:B, 3hf3:C, 3hf3:D, 3hgj:A, 3hgj:B, 3hgj:C, 3hgj:D, 5nux:A, 5nux:B, 5nux:C, 5nux:D, 5ogt:A, 5ogt:B, 5ogt:C, 5ogt:D, 8uaj:A, 8uaj:B, 8uaj:C, 8uaj:D, 8uat:B, 8uat:C, 8uat:D, 8uat:E, 8uat:G, 8uat:H, 8uat:A
17 4v06:A 349 86 0.0366 0.0774 0.3140 2.3 4v06:B, 7wiy:B, 7wiy:C, 7wiy:D, 7wiy:A
18 6l1l:B 393 30 0.0203 0.0382 0.5000 2.5 6l1l:A, 6l1n:A, 6l1n:B, 6l1o:B, 6l1o:A
19 1r5a:A 214 45 0.0203 0.0701 0.3333 4.8
20 2hi4:A 480 61 0.0244 0.0375 0.2951 5.9
21 3gyb:A 261 65 0.0298 0.0843 0.3385 7.2 3gyb:B
22 3t3z:B 464 90 0.0298 0.0474 0.2444 9.1 3e4e:A, 3e4e:B, 3e6i:A, 3e6i:B, 3gph:A, 3gph:B, 3koh:A, 3koh:B, 3lc4:A, 3lc4:B, 3t3z:D, 3t3z:A, 3t3z:C
23 5myj:BQ 125 61 0.0244 0.1440 0.2951 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218